Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.078 0.162 0.286 63.0 -9999.0 0.0 63.0 KIRREL -0.022 0.11 -9999.0 0.0 -0.388 13.0 13.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.078 0.162 -9999.0 0.0 -0.286 63.0 63.0 PLCG1 0.036 0.009 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.031 0.033 -9999.0 0.0 -0.372 1.0 1.0 WASL 0.036 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.046 0.145 -9999.0 0.0 -0.217 69.0 69.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.07 0.135 -9999.0 0.0 -0.236 64.0 64.0 FYN -0.055 0.128 0.264 3.0 -0.21 64.0 67.0 mol:Ca2+ -0.043 0.144 -9999.0 0.0 -0.218 62.0 62.0 mol:DAG -0.042 0.145 -9999.0 0.0 -0.219 62.0 62.0 NPHS2 -0.027 0.104 -9999.0 0.0 -0.385 12.0 12.0 mol:IP3 -0.042 0.145 -9999.0 0.0 -0.219 62.0 62.0 regulation of endocytosis -0.043 0.128 -9999.0 0.0 -0.201 60.0 60.0 Nephrin/NEPH1/podocin/Cholesterol -0.054 0.137 -9999.0 0.0 -0.214 70.0 70.0 establishment of cell polarity -0.078 0.162 -9999.0 0.0 -0.286 63.0 63.0 Nephrin/NEPH1/podocin/NCK1-2 -0.027 0.145 -9999.0 0.0 -0.341 8.0 8.0 Nephrin/NEPH1/beta Arrestin2 -0.042 0.13 -9999.0 0.0 -0.203 60.0 60.0 NPHS1 -0.107 0.191 -9999.0 0.0 -0.381 57.0 57.0 Nephrin/NEPH1/podocin -0.051 0.133 -9999.0 0.0 -0.208 69.0 69.0 TJP1 0.037 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.037 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.038 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.042 0.146 -9999.0 0.0 -0.22 62.0 62.0 CD2AP 0.037 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.045 0.143 -9999.0 0.0 -0.217 62.0 62.0 GRB2 0.035 0.011 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.059 0.123 0.284 3.0 -0.204 62.0 65.0 cytoskeleton organization -0.092 0.149 -9999.0 0.0 -0.286 56.0 56.0 Nephrin/NEPH1 -0.048 0.115 -9999.0 0.0 -0.195 63.0 63.0 Nephrin/NEPH1/ZO-1 -0.045 0.14 -9999.0 0.0 -0.227 59.0 59.0