Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
APC	108 (89%)	14	0.63259	1	0.93776	1	0.32807	0.861	NA	NA	0.64648	1	0.47996	0.947	0.72203	1	0.087279	0.47	0.12839	0.565	0.41975	0.942	NA	NA	NA	NA
CRIPAK	11 (9%)	111	NA	NA	NA	NA	0.2225	0.73	0.33627	0.866	0.29786	0.802	0.10076	0.489	0.00271	0.0874	0.00234	0.0874	0.00017	0.0136	0.00114	0.0608	0.26421	0.755	0.80031	1
TP53	91 (75%)	31	0.0062499	0.136	0.02342	0.292	0.19693	0.675	0.75762	1	0.24526	0.75	0.187	0.675	0.4858	0.947	0.097899	0.489	0.00382	0.108	0.024	0.292	0.48583	0.947	0.17315	0.651
NRAS	11 (9%)	111	0.5773	1	0.68862	1	0.024	0.292	0.65616	1	0.61638	1	0.00343	0.103	0.22795	0.73	0.57303	1	0.56703	1	0.25245	0.755	0.74397	1	0.15048	0.619
FMN2	14 (11%)	108	0.38177	0.915	0.93229	1	0.32709	0.861	0.39327	0.924	0.44743	0.947	0.1055	0.506	0.02543	0.292	0.10832	0.507	0.02115	0.292	0.03016	0.322	0.25786	0.755	0.89778	1
SHROOM4	7 (6%)	115	NA	NA	NA	NA	0.17748	0.66	0.46816	0.947	0.47924	0.947	0.75732	1	0.0262	0.292	0.00248	0.0874	0.00273	0.0874	0.00221	0.0874	0.086049	0.47	0.19173	0.675
RPTN	5 (4%)	117	NA	NA	NA	NA	0.83028	1	1	1	0.03607	0.328	0.46235	0.947	0.066949	0.423	0.04612	0.357	0.02586	0.292	0.069859	0.43	0.89273	1	0.39811	0.924
ARID1A	11 (9%)	111	0.75861	1	0.3406	0.87	0.077379	0.457	0.51956	0.978	0.88541	1	0.15211	0.619	0.63485	1	0.83048	1	0.28622	0.788	0.60477	1	0.89406	1	0.39754	0.924
CDH1	12 (10%)	110	NA	NA	NA	NA	0.54304	0.995	0.55135	1	1	1	0.19523	0.675	0.02056	0.292	0.0053799	0.124	0.00248	0.0874	0.0093299	0.166	0.76121	1	0.22485	0.73
RBM10	6 (5%)	116	0.26364	0.755	0.68873	1	0.42319	0.942	NA	NA	0.40388	0.928	0.80544	1	0.51452	0.978	0.91955	1	0.43481	0.945	0.55262	1	NA	NA	NA	NA
HAUS6	5 (4%)	117	NA	NA	NA	NA	0.10013	0.489	0.86365	1	0.4731	0.947	0.36701	0.915	0.094099	0.475	0.19605	0.675	0.28745	0.788	0.19246	0.675	1	1	0.053059	0.386
CTNNB1	19 (16%)	103	0.21214	0.712	0.42272	0.942	0.42344	0.942	0.7332	1	0.25681	0.755	0.04322	0.346	0.03748	0.328	4e-04	0.024	0.0081999	0.164	0.00025	0.0171	1	1	0.1695	0.651
GABRP	4 (3%)	118	NA	NA	NA	NA	0.43728	0.945	0.61498	1	NA	NA	NA	NA	0.38222	0.915	0.27646	0.776	0.81705	1	0.82434	1	NA	NA	NA	NA
PON3	4 (3%)	118	NA	NA	NA	NA	0.22827	0.73	1	1	NA	NA	NA	NA	0.056149	0.396	0.071489	0.434	0.02179	0.292	0.0333	0.328	0.089799	0.47	0.88739	1
RLIM	4 (3%)	118	NA	NA	NA	NA	1	1	0.41983	0.942	0.47138	0.947	0.53996	0.993	0.066029	0.423	0.03975	0.329	0.47196	0.947	0.51754	0.978	NA	NA	NA	NA
SMAD2	6 (5%)	116	0.49385	0.952	0.93374	1	0.38558	0.916	0.92468	1	0.13766	0.59	0.35178	0.893	0.96385	1	0.98898	1	0.73761	1	0.64081	1	NA	NA	NA	NA
TCF7L2	12 (10%)	110	0.48441	0.947	0.52399	0.982	0.080839	0.462	0.10879	0.507	0.57504	1	0.13415	0.585	0.98749	1	0.66901	1	0.67861	1	0.84237	1	0.49039	0.949	0.61589	1
OXSM	4 (3%)	118	NA	NA	NA	NA	0.699	1	0.48748	0.947	0.37097	0.915	0.079039	0.457	0.51487	0.978	0.084549	0.47	0.47713	0.947	0.3829	0.915	NA	NA	NA	NA
PCBP1	5 (4%)	117	NA	NA	NA	NA	0.23892	0.74	0.23699	0.739	0.26228	0.755	0.64766	1	0.03557	0.328	0.55463	1	0.70455	1	0.58455	1	NA	NA	NA	NA
KRAS	63 (52%)	59	0.00431	0.109	0.00409	0.109	0.12786	0.565	0.25226	0.755	0.30087	0.802	0.03624	0.328	0.43311	0.945	0.15786	0.626	1	1	0.053829	0.386	0.79948	1	0.092899	0.475
FLT1	8 (7%)	114	NA	NA	NA	NA	0.33526	0.866	1	1	0.55046	1	0.33116	0.864	0.051029	0.383	0.22218	0.73	0.17026	0.651	0.38066	0.915	0.15899	0.626	0.44105	0.947
SLC12A6	6 (5%)	116	NA	NA	NA	NA	0.0313	0.327	0.47311	0.947	0.17186	0.651	0.87052	1	0.03937	0.329	0.15087	0.619	0.5258	0.982	0.32781	0.861	NA	NA	NA	NA
AKAP9	7 (6%)	115	0.44984	0.947	0.84332	1	0.25405	0.755	0.4026	0.928	0.24377	0.75	0.26286	0.755	0.066699	0.423	0.03645	0.328	1	1	0.67712	1	NA	NA	NA	NA
VCX2	5 (4%)	117	NA	NA	NA	NA	1	1	0.29618	0.802	0.56999	1	0.14473	0.614	0.062929	0.42	0.12225	0.559	0.01657	0.274	0.0089199	0.166	0.7216	1	0.58993	1
ELF3	4 (3%)	118	0.45067	0.947	0.84441	1	0.43568	0.945	NA	NA	0.37229	0.915	0.15572	0.623	0.30046	0.802	0.15055	0.619	1	1	0.29163	0.795	NA	NA	NA	NA
PIK3CA	36 (30%)	86	0.12718	0.565	0.85647	1	0.8306	1	0.70423	1	0.086609	0.47	0.26339	0.755	9.9999e-06	0.0012	9.9999e-06	0.0012	9.9999e-06	0.0012	9.9999e-06	0.0012	0.82357	1	0.38299	0.915
BRAF	13 (11%)	109	0.093019	0.475	0.22031	0.73	0.10039	0.489	0.27211	0.773	0.84491	1	0.01613	0.274	0.0090499	0.166	0.1223	0.559	0.03621	0.328	0.03779	0.328	0.84256	1	0.02676	0.292
KIAA1804	10 (8%)	112	0.74208	1	0.68093	1	0.20285	0.691	NA	NA	0.52867	0.984	0.45874	0.947	0.46912	0.947	0.45827	0.947	0.050809	0.383	0.0054399	0.124	NA	NA	NA	NA
ERBB2	9 (7%)	113	0.68026	1	0.53126	0.985	0.87723	1	0.33743	0.866	0.10758	0.507	0.3926	0.924	0.02049	0.292	0.078249	0.457	0.72072	1	0.37986	0.915	1	1	0.80218	1
CDKL5	4 (3%)	118	NA	NA	NA	NA	0.90574	1	0.92557	1	1	1	0.80081	1	0.058379	0.406	0.37414	0.915	0.28066	0.783	0.51612	0.978	NA	NA	NA	NA
ZNF354C	5 (4%)	117	NA	NA	NA	NA	0.61902	1	0.47381	0.947	0.04162	0.339	0.71173	1	0.01895	0.292	0.20747	0.701	0.18015	0.665	0.19186	0.675	1	1	0.051849	0.383
LIG1	4 (3%)	118	NA	NA	NA	NA	0.56915	1	1	1	0.7237	1	0.53823	0.993	0.02474	0.292	0.12482	0.565	0.02229	0.292	0.03325	0.328	NA	NA	NA	NA
IQCD	3 (2%)	119	NA	NA	NA	NA	0.65826	1	NA	NA	NA	NA	NA	NA	0.089749	0.47	0.27456	0.775	0.56369	1	0.5705	1	NA	NA	NA	NA
ZBED4	4 (3%)	118	NA	NA	NA	NA	0.36321	0.913	0.9253	1	0.062759	0.42	0.46186	0.947	0.04609	0.357	0.56616	1	0.81881	1	1	1	NA	NA	NA	NA
GMCL1	4 (3%)	118	NA	NA	NA	NA	1	1	0.15491	0.623	0.13746	0.59	0.4637	0.947	0.089369	0.47	0.22778	0.73	0.47449	0.947	0.5166	0.978	1	1	0.23641	0.739
CIR1	3 (2%)	119	NA	NA	NA	NA	0.65774	1	0.92477	1	NA	NA	NA	NA	0.14574	0.614	0.23296	0.736	0.059789	0.41	0.19347	0.675	NA	NA	NA	NA
AGL	4 (3%)	118	NA	NA	NA	NA	0.19144	0.675	NA	NA	0.26388	0.755	0.85297	1	0.35403	0.894	0.6968	1	0.64091	1	0.82423	1	NA	NA	NA	NA
FAM123B	10 (8%)	112	0.57619	1	0.39827	0.924	0.068999	0.43	0.45022	0.947	0.42865	0.944	0.42195	0.942	0.42538	0.942	0.28433	0.788	1	1	0.67443	1	NA	NA	NA	NA
VANGL1	3 (2%)	119	NA	NA	NA	NA	0.0067999	0.142	NA	NA	1	1	1	1	0.066529	0.423	0.23225	0.736	0.02576	0.292	0.19311	0.675	NA	NA	NA	NA
CREBBP	10 (8%)	112	NA	NA	NA	NA	0.090049	0.47	0.65692	1	0.16904	0.651	0.42567	0.942	2e-05	0.00192	0.03824	0.328	0.075029	0.45	0.17369	0.651	0.93851	1	0.60738	1