Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.025 0.149 0.6 10.0 -9999.0 0.0 10.0 KIRREL 0.008 0.018 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.025 0.149 -9999.0 0.0 -0.601 10.0 10.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.016 0.138 -9999.0 0.0 -0.49 12.0 12.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.001 0.089 -9999.0 0.0 -0.52 2.0 2.0 FYN -0.018 0.123 -9999.0 0.0 -0.44 12.0 12.0 mol:Ca2+ -0.015 0.136 -9999.0 0.0 -0.485 12.0 12.0 mol:DAG -0.014 0.137 -9999.0 0.0 -0.488 12.0 12.0 NPHS2 -0.013 0.109 -9999.0 0.0 -0.808 3.0 3.0 mol:IP3 -0.014 0.137 -9999.0 0.0 -0.488 12.0 12.0 regulation of endocytosis -0.007 0.118 -9999.0 0.0 -0.412 12.0 12.0 Nephrin/NEPH1/podocin/Cholesterol -0.022 0.137 -9999.0 0.0 -0.495 12.0 12.0 establishment of cell polarity -0.025 0.149 -9999.0 0.0 -0.6 10.0 10.0 Nephrin/NEPH1/podocin/NCK1-2 -0.005 0.129 -9999.0 0.0 -0.45 12.0 12.0 Nephrin/NEPH1/beta Arrestin2 -0.007 0.12 -9999.0 0.0 -0.418 12.0 12.0 NPHS1 -0.037 0.189 -9999.0 0.0 -0.782 10.0 10.0 Nephrin/NEPH1/podocin -0.015 0.124 -9999.0 0.0 -0.443 12.0 12.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.014 0.138 -9999.0 0.0 -0.49 12.0 12.0 CD2AP 0.012 0.002 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.014 0.138 -9999.0 0.0 -0.49 12.0 12.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.018 0.129 -9999.0 0.0 -0.46 12.0 12.0 cytoskeleton organization -0.003 0.11 -9999.0 0.0 -0.524 3.0 3.0 Nephrin/NEPH1 -0.017 0.111 -9999.0 0.0 -0.447 10.0 10.0 Nephrin/NEPH1/ZO-1 -0.011 0.125 -9999.0 0.0 -0.493 10.0 10.0