Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.041	0.168	0.391	1.0	-0.575	5.0	6.0
IHH	-0.095	0.246	0.244	1.0	-0.583	51.0	52.0
SHH Np/Cholesterol/GAS1	-0.055	0.111	-9999.0	0.0	-0.32	37.0	37.0
LRPAP1	0.019	0.004	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.055	0.11	0.318	37.0	-9999.0	0.0	37.0
SMO/beta Arrestin2	-0.079	0.196	0.317	1.0	-0.418	52.0	53.0
SMO	-0.089	0.197	-9999.0	0.0	-0.435	52.0	52.0
AKT1	-0.037	0.121	-9999.0	0.0	-0.489	7.0	7.0
ARRB2	0.018	0.005	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.019	0.06	0.254	5.0	-0.549	2.0	7.0
ADRBK1	0.019	0.003	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.089	0.195	-9999.0	0.0	-0.428	53.0	53.0
STIL	-0.063	0.169	0.28	8.0	-0.362	27.0	35.0
DHH N/PTCH2	0.014	0.099	-9999.0	0.0	-0.407	12.0	12.0
DHH N/PTCH1	-0.049	0.17	0.331	1.0	-0.329	61.0	62.0
PIK3CA	0.019	0.003	-9999.0	0.0	-9999.0	0.0	0.0
DHH	-0.003	0.12	0.254	4.0	-0.549	11.0	15.0
PTHLH	-0.071	0.231	0.482	1.0	-1.05	5.0	6.0
determination of left/right symmetry	-0.089	0.195	-9999.0	0.0	-0.428	53.0	53.0
PIK3R1	0.02	0.015	0.254	1.0	-9999.0	0.0	1.0
skeletal system development	-0.07	0.229	0.481	1.0	-1.033	5.0	6.0
IHH N/Hhip	-0.118	0.24	0.248	8.0	-0.435	86.0	94.0
DHH N/Hhip	-0.06	0.192	-9999.0	0.0	-0.415	55.0	55.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.089	0.195	-9999.0	0.0	-0.428	53.0	53.0
pancreas development	-0.076	0.229	0.254	14.0	-0.548	46.0	60.0
HHAT	0.019	0.004	-9999.0	0.0	-9999.0	0.0	0.0
PI3K	0.028	0.017	-9999.0	0.0	-0.173	1.0	1.0
EntrezGene:84976	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.019	0.041	0.254	2.0	-0.549	1.0	3.0
somite specification	-0.089	0.195	-9999.0	0.0	-0.428	53.0	53.0
SHH Np/Cholesterol/PTCH1	-0.081	0.17	0.324	1.0	-0.314	78.0	79.0
SHH Np/Cholesterol/PTCH2	-0.049	0.118	0.218	2.0	-0.32	37.0	39.0
SHH Np/Cholesterol/Megalin	-0.193	0.181	-9999.0	0.0	-0.353	134.0	134.0
SHH	-0.069	0.138	-9999.0	0.0	-0.407	36.0	36.0
catabolic process	-0.047	0.168	0.286	9.0	-0.344	54.0	63.0
SMO/Vitamin D3	-0.102	0.192	0.385	2.0	-0.393	53.0	55.0
SHH Np/Cholesterol/Hhip	-0.1	0.173	0.275	1.0	-0.355	72.0	73.0
LRP2	-0.252	0.274	-9999.0	0.0	-0.549	117.0	117.0
receptor-mediated endocytosis	-0.211	0.216	0.278	1.0	-0.528	57.0	58.0
SHH Np/Cholesterol/BOC	-0.054	0.114	-9999.0	0.0	-0.318	38.0	38.0
SHH Np/Cholesterol/CDO	-0.053	0.111	0.159	3.0	-0.319	36.0	39.0
mesenchymal cell differentiation	0.099	0.171	0.352	72.0	-0.272	1.0	73.0
mol:Vitamin D3	-0.085	0.172	0.332	3.0	-0.317	75.0	78.0
IHH N/PTCH2	-0.044	0.17	0.239	9.0	-0.366	52.0	61.0
CDON	0.022	0.03	0.254	4.0	-9999.0	0.0	4.0
IHH N/PTCH1	-0.042	0.171	0.275	7.0	-0.347	54.0	61.0
Megalin/LRPAP1	-0.17	0.214	-9999.0	0.0	-0.398	118.0	118.0
PTCH2	0.026	0.058	0.254	10.0	-0.549	1.0	11.0
SHH Np/Cholesterol	-0.053	0.107	-9999.0	0.0	-0.316	36.0	36.0
PTCH1	-0.047	0.169	0.286	9.0	-0.345	54.0	63.0
HHIP	-0.076	0.229	0.254	14.0	-0.549	46.0	60.0