Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.087 0.166 0.304 135.0 -9999.0 0.0 135.0 KIRREL 0.001 0.051 -9999.0 0.0 -0.425 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.088 0.166 -9999.0 0.0 -0.304 135.0 135.0 PLCG1 0.033 0.01 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.033 0.009 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.031 0.011 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.039 0.136 -9999.0 0.0 -0.226 122.0 122.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.06 0.118 -9999.0 0.0 -0.229 119.0 119.0 FYN -0.055 0.133 0.274 15.0 -0.215 134.0 149.0 mol:Ca2+ -0.041 0.135 -9999.0 0.0 -0.224 124.0 124.0 mol:DAG -0.041 0.136 -9999.0 0.0 -0.225 124.0 124.0 NPHS2 -0.01 0.038 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.041 0.136 -9999.0 0.0 -0.225 124.0 124.0 regulation of endocytosis -0.045 0.122 -9999.0 0.0 -0.202 133.0 133.0 Nephrin/NEPH1/podocin/Cholesterol -0.054 0.131 -9999.0 0.0 -0.224 134.0 134.0 establishment of cell polarity -0.087 0.166 -9999.0 0.0 -0.304 135.0 135.0 Nephrin/NEPH1/podocin/NCK1-2 -0.029 0.138 -9999.0 0.0 -0.207 132.0 132.0 Nephrin/NEPH1/beta Arrestin2 -0.044 0.124 -9999.0 0.0 -0.204 133.0 133.0 NPHS1 -0.148 0.219 -9999.0 0.0 -0.415 146.0 146.0 Nephrin/NEPH1/podocin -0.053 0.125 -9999.0 0.0 -0.216 134.0 134.0 TJP1 0.034 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.034 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.035 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.04 0.137 -9999.0 0.0 -0.226 124.0 124.0 CD2AP 0.031 0.026 -9999.0 0.0 -0.417 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 -0.043 0.14 -9999.0 0.0 -0.226 131.0 131.0 GRB2 0.034 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.058 0.126 0.25 23.0 -0.203 132.0 155.0 cytoskeleton organization -0.081 0.142 0.203 5.0 -0.285 117.0 122.0 Nephrin/NEPH1 -0.056 0.117 -9999.0 0.0 -0.207 135.0 135.0 Nephrin/NEPH1/ZO-1 -0.055 0.142 -9999.0 0.0 -0.239 134.0 134.0