Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.058 0.198 0.538 56.0 -9999.0 0.0 56.0 KIRREL -0.001 0.07 -9999.0 0.0 -0.658 4.0 4.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.058 0.199 -9999.0 0.0 -0.539 56.0 56.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.058 0.153 -9999.0 0.0 -0.51 38.0 38.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.01 0.108 -9999.0 0.0 -0.605 1.0 1.0 FYN -0.034 0.147 -9999.0 0.0 -0.461 38.0 38.0 mol:Ca2+ -0.057 0.152 -9999.0 0.0 -0.504 38.0 38.0 mol:DAG -0.057 0.152 -9999.0 0.0 -0.507 38.0 38.0 NPHS2 -0.007 0.077 -9999.0 0.0 -0.872 3.0 3.0 mol:IP3 -0.057 0.152 -9999.0 0.0 -0.507 38.0 38.0 regulation of endocytosis -0.025 0.139 -9999.0 0.0 -0.431 38.0 38.0 Nephrin/NEPH1/podocin/Cholesterol -0.059 0.156 -9999.0 0.0 -0.517 38.0 38.0 establishment of cell polarity -0.058 0.198 -9999.0 0.0 -0.538 56.0 56.0 Nephrin/NEPH1/podocin/NCK1-2 -0.052 0.14 -9999.0 0.0 -0.466 38.0 38.0 Nephrin/NEPH1/beta Arrestin2 -0.024 0.141 -9999.0 0.0 -0.436 38.0 38.0 NPHS1 -0.08 0.249 -9999.0 0.0 -0.716 52.0 52.0 Nephrin/NEPH1/podocin -0.034 0.148 -9999.0 0.0 -0.464 38.0 38.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.058 0.153 -9999.0 0.0 -0.51 38.0 38.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.058 0.153 -9999.0 0.0 -0.51 38.0 38.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.031 0.149 -9999.0 0.0 -0.47 38.0 38.0 cytoskeleton organization -0.015 0.139 -9999.0 0.0 -0.823 1.0 1.0 Nephrin/NEPH1 -0.041 0.149 -9999.0 0.0 -0.488 37.0 37.0 Nephrin/NEPH1/ZO-1 -0.059 0.158 -9999.0 0.0 -0.54 36.0 36.0