Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.0 0.101 0.259 53.0 -9999.0 0.0 53.0 KIRREL 0.017 0.046 -9999.0 0.0 -0.374 4.0 4.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.001 0.101 -9999.0 0.0 -0.26 53.0 53.0 PLCG1 0.023 0.011 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.029 0.086 -9999.0 0.0 -0.215 17.0 17.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.004 0.061 -9999.0 0.0 -0.223 19.0 19.0 FYN -0.004 0.08 0.24 12.0 -0.202 21.0 33.0 mol:Ca2+ 0.024 0.081 -9999.0 0.0 -0.19 44.0 44.0 mol:DAG 0.025 0.081 -9999.0 0.0 -0.19 44.0 44.0 NPHS2 0.013 0.041 -9999.0 0.0 -0.364 3.0 3.0 mol:IP3 0.025 0.081 -9999.0 0.0 -0.19 44.0 44.0 regulation of endocytosis 0.022 0.075 -9999.0 0.0 -0.194 17.0 17.0 Nephrin/NEPH1/podocin/Cholesterol 0.015 0.082 -9999.0 0.0 -0.188 55.0 55.0 establishment of cell polarity 0.0 0.101 -9999.0 0.0 -0.259 53.0 53.0 Nephrin/NEPH1/podocin/NCK1-2 0.04 0.087 -9999.0 0.0 -0.31 1.0 1.0 Nephrin/NEPH1/beta Arrestin2 0.024 0.077 -9999.0 0.0 -0.196 17.0 17.0 NPHS1 -0.022 0.129 -9999.0 0.0 -0.363 51.0 51.0 Nephrin/NEPH1/podocin 0.018 0.077 -9999.0 0.0 -0.18 41.0 41.0 TJP1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.026 0.082 -9999.0 0.0 -0.191 44.0 44.0 CD2AP 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.028 0.09 -9999.0 0.0 -0.197 41.0 41.0 GRB2 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.013 0.078 0.214 18.0 -0.194 18.0 36.0 cytoskeleton organization -0.008 0.073 0.207 6.0 -0.262 19.0 25.0 Nephrin/NEPH1 0.006 0.07 -9999.0 0.0 -0.174 53.0 53.0 Nephrin/NEPH1/ZO-1 0.019 0.087 -9999.0 0.0 -0.203 52.0 52.0