Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.021 0.117 0.254 1.0 -0.406 12.0 13.0 MAP3K8 0.026 0.02 -9999.0 0.0 -0.363 1.0 1.0 FOS 0.011 0.101 0.259 1.0 -0.375 13.0 14.0 PRKCA 0.025 0.012 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.02 0.048 -9999.0 0.0 -0.357 6.0 6.0 HRAS 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.001 0.097 -9999.0 0.0 -0.385 24.0 24.0 NRAS 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.043 0.023 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.015 0.092 -9999.0 0.0 -0.514 9.0 9.0 MAP2K1 0.003 0.098 -9999.0 0.0 -0.356 22.0 22.0 ELK1 0.025 0.014 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.001 0.084 -9999.0 0.0 -0.34 22.0 22.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.005 23.0 23.0 MAPK1 0.011 0.096 -9999.0 0.0 -0.415 14.0 14.0 RAF1 0.001 0.084 -9999.0 0.0 -0.34 22.0 22.0 KRAS 0.025 0.009 -9999.0 0.0 -9999.0 0.0 0.0