Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.059 0.2 0.593 73.0 -9999.0 0.0 73.0 KIRREL 0.004 0.033 -9999.0 0.0 -0.454 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.059 0.201 -9999.0 0.0 -0.594 73.0 73.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.056 0.15 -9999.0 0.0 -0.459 71.0 71.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.004 0.098 -9999.0 0.0 -0.551 1.0 1.0 FYN -0.031 0.142 -9999.0 0.0 -0.413 71.0 71.0 mol:Ca2+ -0.055 0.148 -9999.0 0.0 -0.455 71.0 71.0 mol:DAG -0.055 0.149 -9999.0 0.0 -0.457 71.0 71.0 NPHS2 -0.003 0.053 -9999.0 0.0 -0.829 2.0 2.0 mol:IP3 -0.055 0.149 -9999.0 0.0 -0.457 71.0 71.0 regulation of endocytosis -0.022 0.135 -9999.0 0.0 -0.385 71.0 71.0 Nephrin/NEPH1/podocin/Cholesterol -0.056 0.152 -9999.0 0.0 -0.467 71.0 71.0 establishment of cell polarity -0.059 0.2 -9999.0 0.0 -0.593 73.0 73.0 Nephrin/NEPH1/podocin/NCK1-2 -0.05 0.136 -9999.0 0.0 -0.417 71.0 71.0 Nephrin/NEPH1/beta Arrestin2 -0.022 0.137 -9999.0 0.0 -0.389 71.0 71.0 NPHS1 -0.084 0.259 -9999.0 0.0 -0.788 71.0 71.0 Nephrin/NEPH1/podocin -0.033 0.143 -9999.0 0.0 -0.416 71.0 71.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.056 0.15 -9999.0 0.0 -0.459 71.0 71.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.056 0.15 -9999.0 0.0 -0.459 71.0 71.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.03 0.146 -9999.0 0.0 -0.422 71.0 71.0 cytoskeleton organization -0.008 0.127 -9999.0 0.0 -0.548 2.0 2.0 Nephrin/NEPH1 -0.042 0.15 -9999.0 0.0 -0.451 70.0 70.0 Nephrin/NEPH1/ZO-1 -0.059 0.159 -9999.0 0.0 -0.494 70.0 70.0