Hybridization REF	p	difference	q	subclass
Composite Element REF	p	difference	q	subclass
RAD50|RAD50	0.0170243821413816	1.44252821932924	0.0877904068187389	1
CDKN1A|P21	9.54012293376126e-07	1.35073257533817	9.15851801641081e-05	1
GSK3A GSK3B|GSK3_PS9	1.83758777000887e-06	1.15134610164174	0.000117605617280568	1
SRC|SRC_PY527	0.000154253188822244	1.12084982279799	0.00370207653173386	1
PDK1|PDK1	0.0124074618614272	0.743540108445312	0.0744447711685632	1
GAB2|GAB2	0.00872556120152861	0.740024691731027	0.0620484352108701	1
AKT1 AKT2 AKT3|AKT_PS473	0.0328758271844238	0.712435327802455	0.136531230454042	1
NRG1|HEREGULIN	0.00908919314838213	0.681200331614955	0.0623258958746203	1
GSK3A GSK3B|GSK3-ALPHA-BETA_PS21_S9	1.97617857828052e-05	0.655695949418527	0.00094856571757465	1
TSC2|TUBERIN_PT1462	0.00185871951899685	0.634317653623884	0.0254910105462425	1
EIF4EBP1|4E-BP1_PT37_T46	0.00180639253804385	0.617199180030134	0.0254910105462425	1
MAP2K1|MEK1	0.00542854345103608	0.58389821005692	0.0496323972666156	1
YAP1|YAP_PS127	0.0084262325316737	0.579850381878348	0.0620484352108701	1
AKT1 AKT2 AKT3|AKT_PT308	0.0400774433790822	0.530093604891741	0.150879786838898	1
SFRS1|SF2	0.00519614868346761	0.511000486373884	0.0496323972666156	1
TSC2|TUBERIN	0.0161399051547306	0.438055828208705	0.0860794941585632	1
RB1|RB_PS807_S811	0.0432105726698327	0.42918305727567	0.153637591714961	1
RBM15|RBM15	0.0231170089375749	0.399931494454241	0.11096164290036	1
FRAP1|MTOR_PS2448	0.00115693195511466	0.395607224168527	0.020193721398365	1
BECN1|BECLIN	0.00245400656883496	0.385444889016741	0.0314112840810875	1
ERBB3|HER3	0.012068492189555	0.377847487922991	0.0744447711685632	1
PXN|PAXILLIN	0.00994504683041559	0.368886951811384	0.0658430686703377	1
DVL3|DVL3	0.0146428083132359	0.309448564226562	0.0826887998865086	1
BAD|BAD_PS112	0.00633049871826948	0.293185660422991	0.0544547953209445	1
AKT1S1|PRAS40_PT246	8.11680650845262e-05	0.288148139972098	0.00222632407088986	1
PRKAA1|AMPK_ALPHA	0.0150894161411351	0.275767633030134	0.0827762256885125	1
CHEK1|CHK1_PS345	0.00862634916774253	0.247816724405134	0.0620484352108701	1
EIF4G1|EIF4G	0.0334217074548956	0.223871997606027	0.136531230454042	1
YBX1|YB-1_PS102	2.72540302781883e-05	0.199248958012277	0.00104655476268243	1
BIRC2 |CIAP	0.000780538846525166	0.185679412159598	0.0149863458532832	1
MAPK9|JNK2	0.0424399966930417	0.184771737655134	0.153637591714961	1
EIF4EBP1|4E-BP1_PS65	0.0210278595723028	0.178210926445313	0.103521770202106	1
FOXO3|FOXO3A_PS318_S321	0.0350433366735109	0.145473486253348	0.137312666149267	1
BRCA2|BRCA2	0.0365860585370056	0.107796901981027	0.140490464782101	1
CDKN1B|P27_PT157	0.00780369040788826	-0.0765854863046875	0.0620484352108701	1
MET|C-MET_PY1235	0.0350325924467739	-0.0967003014921875	0.137312666149267	1
PRKCD|PKC-DELTA_PS664	0.0330781712519938	-0.103683589795759	0.136531230454042	1
MRE11A|MRE11	0.0499845845822326	-0.136552974175223	0.174267041072665	1
RAB11A RAB11B|RAB11	0.0244043882366472	-0.142596503358259	0.113117645381793	1
ADAR|ADAR1	0.0247444849272672	-0.16208770919308	0.113117645381793	1
LCK|LCK	0.0322773772410402	-0.185067637831473	0.136531230454042	1
PIK3R1|PI3K-P85	0.0431464431333878	-0.195997303527902	0.153637591714961	1
GATA3|GATA3	0.0173751846828754	-0.224177760822545	0.0877904068187389	1
G6PD|G6PD	0.00291374501613961	-0.254336497237723	0.0349649401936753	1
PCNA|PCNA	0.0005178587650514	-0.257110531835938	0.0110476536544299	1
PREX1|PREX1	0.00371025104884841	-0.264640038291295	0.0419040118458173	1
PRKCA |PKC-ALPHA	0.0142227284636036	-0.296714023112723	0.0826887998865086	1
PRKCA |PKC-ALPHA_PS657	0.0296145436425886	-0.334169025103795	0.132232380915744	1
ANXA7 |ANNEXIN_VII	0.00135233421166138	-0.346845408434152	0.0216373473865821	1
RPS6|S6_PS240_S244	0.0116972747542482	-0.43034784972433	0.0744447711685632	1
ESR1|ER-ALPHA	0.00401643627566405	-0.471468526425223	0.0428419869404165	1
BAX|BAX	3.75905588581995e-10	-0.487505671822545	7.2173873007743e-08	1
RPS6KA1|P90RSK	0.00538979116693712	-0.52466067969308	0.0496323972666156	1
SYK|SYK	0.00652323068948814	-0.526878583398438	0.0544547953209445	1
CASP7|CASPASE-7_CLEAVEDD198	3.98370958133303e-05	-0.587469189916295	0.00127478706602657	1
TP53BP1|53BP1	0.00155823011694055	0.617830096639113	0.0299180182452586	2
MSH6|MSH6	0.00018599390438326	0.579689304614919	0.00892770741039648	2
BAP1|BAP1-C-4	8.86005482201576e-06	0.512607692368952	0.000843450444297363	2
BRAF|B-RAF	0.000318542453018637	0.414788862118952	0.0122320301959157	2
RPS6|S6	0.00304606836081531	0.402623408715726	0.048737093773045	2
FRAP1|MTOR	0.0344693025685047	0.370984733042339	0.17718108900907	2
CCNB1|CYCLIN_B1	0.0140350687305575	0.346024016183468	0.117162312881176	2
XRCC1|XRCC1	0.00793506786193279	0.3163576024375	0.0846407238606164	2
MSH2|MSH2	0.00446899482098445	0.308577418381048	0.0612890718306439	2
CHEK1|CHK1	0.0266417837595871	0.285185349203629	0.159904781508136	2
CCNE2|CYCLIN_E2	0.00403294759132031	0.278725542381048	0.059563533656423	2
RPS6KA1|P90RSK	0.0274836343217109	0.226339814764113	0.159904781508136	2
GSK3A GSK3B|GSK3-ALPHA-BETA	0.0320689279006625	0.196334658340726	0.175920975912206	2
BAK1|BAK	0.0158549869763564	0.191339838465726	0.117396007295488	2
PCNA|PCNA	0.0465412460714568	0.184752606300403	0.201656808948038	2
RAF1|C-RAF	0.0393039918458643	0.183736709921371	0.18405771791234	2
ESR1|ER-ALPHA_PS118	0.00095213133938823	0.159565287453629	0.0257156877664582	2
RPTOR|RAPTOR	0.0271238630535458	0.142678397344758	0.159904781508136	2
ADAR|ADAR1	0.00236077296331335	0.137901489034274	0.0412062189960148	2
SMAD3|SMAD3	0.0189133788828651	0.126993803308468	0.128825607013076	2
CDKN1B|P27_PT157	0.0158973759879307	0.0793702403850807	0.117396007295488	2
BRCA2|BRCA2	0.0110312010548444	-0.110048743332661	0.103741071007874	2
BIRC2 |CIAP	0.0057215814804262	-0.141971384030242	0.0686589777651144	2
IRS1|IRS1	0.0430583389421427	-0.14564185409879	0.192260490160265	2
RICTOR|RICTOR_PT1135	0.0350670905330452	-0.148142413485887	0.17718108900907	2
MAPK8|JNK_PT183_PY185	0.0118869977196522	-0.148924002614919	0.103741071007874	2
MAP2K1|MEK1_PS217_S221	0.00521476042869112	-0.161265312066532	0.0667489334872463	2
ETS1|ETS-1	0.0194580343926	-0.163665385235887	0.128825607013076	2
FRAP1|MTOR_PS2448	0.0363366889989487	-0.211924692280242	0.178888315071747	2
XBP1|XBP1	0.0429646905007006	-0.219413420050403	0.192260490160265	2
ERBB2|HER2_PY1248	0.0230067446768136	-0.234310783465726	0.147243165931607	2
MYH9|MYOSIN-IIA_PS1943	0.0174487612914478	-0.3211755525625	0.12408008029474	2
CASP7|CASPASE-7_CLEAVEDD198	0.0329873404078919	-0.354268121719758	0.175932482175423	2
RPS6|S6_PS235_S236	0.0472633145971964	-0.375188378054435	0.201656808948038	2
RAD50|RAD50	0.0385169156236448	-0.385826973546371	0.18405771791234	2
STAT3|STAT3_PY705	0.00696699288948543	-0.411785849195564	0.0786860373400707	2
MAPK1 MAPK3|MAPK_PT202_Y204	4.62445916669494e-06	-0.48224355684879	0.000843450444297363	2
ESR1|ER-ALPHA	0.00124839751418524	-0.522066536296371	0.0266324803026185	2
ASNS|ASNS	0.03098272864317	-0.543955910489919	0.174961291161431	2
ANXA1|ANNEXIN-1	0.0150035296258082	-0.552557406300403	0.117396007295488	2
MAPK14|P38_PT180_Y182	0.0118834857169179	-0.629274805139113	0.103741071007874	2
SERPINE1|PAI-1	0.00909100862980626	-0.636552116260081	0.0918670345748843	2
AKT1 AKT2 AKT3|AKT_PT308	0.00107148699026909	-0.697258092372984	0.0257156877664582	2
NDRG1|NDRG1_PT346	0.000404670759293971	-0.81341379359879	0.0129494642974071	2
AKT1 AKT2 AKT3|AKT_PS473	1.31789131921463e-05	-1.13091506875202	0.000843450444297363	2
CDH1|E-CADHERIN	0.000460319037159498	1.75271586100649	0.00883812551346236	3
MYH11|MYH11	0.00447535868766971	1.55744708043182	0.0330488026166379	3
VHL|VHL	1.34795033798035e-05	1.24965469771104	0.00258806464892227	3
ESR1|ER-ALPHA	0.000206108834623488	1.15127685596753	0.00565327089252996	3
RAB25|RAB25	0.000150304841764384	0.737427359853896	0.00565327089252996	3
CTNNB2|BETA-CATENIN	0.00273282163172067	0.662320824714286	0.0262350876645184	3
CLDN7|CLAUDIN-7	0.0207134609295442	0.605966829795454	0.0924463164298905	3
PDCD4|PDCD4	0.0120680409303962	0.586265079818182	0.0611263153193775	3
SYK|SYK	0.0259238601001276	0.548240241405844	0.108203937809228	3
RPS6|S6_PS235_S236	0.0137203527751459	0.546643486282468	0.0675463521237952	3
STAT3|STAT3_PY705	0.00186582452664451	0.521767541357143	0.0188546478481972	3
MYH9|MYOSIN-IIA_PS1943	0.000524883390274447	0.496741770538961	0.00916160099388126	3
PKC|PKC-PAN_BETAII_PS660	0.00489682986270312	0.469879386220779	0.034198647199729	3
PRKCA |PKC-ALPHA_PS657	0.00369069004298437	0.450145758574675	0.029921778790151	3
FASN|FASN	0.0277389281485543	0.394099411350649	0.110955712594217	3
RB1|RB_PS807_S811	0.0330929733754556	0.376874917136364	0.122491468277147	3
GATA3|GATA3	0.00913453312210848	0.375273157477273	0.0529337413046814	3
ACACA ACACB|ACC_PS79	0.0494302188295681	0.370623366035714	0.165409973784011	3
BCL2L11|BIM	0.0419195435651857	0.367213084545455	0.151859478575767	3
PRKCA |PKC-ALPHA	0.00861074519226279	0.314901861188312	0.0516644711535767	3
TGM2|TRANSGLUTAMINASE	0.0147487653817464	0.299091207935065	0.0697231215433662	3
MSH2|MSH2	0.0118988874929676	0.274357579603896	0.0611263153193775	3
CDH3|P-CADHERIN	0.044978409643284	0.250612852840909	0.158522782759549	3
RPS6KA1|P90RSK	0.0456575473954108	0.242637362162338	0.158522782759549	3
JUN|C-JUN_PS73	0.0304486856562658	0.205555598496753	0.116922952920061	3
ANXA7 |ANNEXIN_VII	0.0462358116382019	0.201058681652597	0.158522782759549	3
CTNNB1|ALPHA-CATENIN	0.0072508078209542	0.200576254603896	0.0449082290846196	3
CDC2|CDK1	0.0120979165736268	0.179233727597403	0.0611263153193775	3
PRKCD|PKC-DELTA_PS664	0.000612163002183411	0.179184034931818	0.00979460803493458	3
ADAR|ADAR1	0.0211856141818499	0.117358040175325	0.0924463164298905	3
RAF1|C-RAF_PS338	0.0273966960705956	-0.110789557912338	0.110955712594217	3
CDKN1B|P27_PT157	0.000202145857532232	-0.11685544287987	0.00565327089252996	3
MRE11A|MRE11	0.0331747726583941	-0.128970465922078	0.122491468277147	3
MET|C-MET_PY1235	0.00678796703603987	-0.13284581276948	0.0434429890306552	3
AKT1S1|PRAS40_PT246	0.0178242368930533	-0.141312700350649	0.0814822257968151	3
BRCA2|BRCA2	0.0105053183733683	-0.14891078125974	0.0576291750767632	3
CDH2|N-CADHERIN	0.0220091630443703	-0.156286910698052	0.0939057623226466	3
NRAS|N-RAS	0.00179259864832444	-0.159948928048701	0.0188546478481972	3
CHEK2|CHK2_PT68	0.028735792309047	-0.162076447649351	0.112597390272184	3
RAF1|C-RAF	0.00380447083218953	-0.164763719366883	0.029921778790151	3
YBX1|YB-1_PS102	0.00498730271662715	-0.168655031827922	0.034198647199729	3
PEA15|PEA15_PS116	0.0499675962472534	-0.184074334272727	0.165409973784011	3
RPTOR|RAPTOR	0.014888791579573	-0.190348695678571	0.0697231215433662	3
SMAD3|SMAD3	0.000291535428223034	-0.214006216847403	0.00699685027735282	3
EGFR|EGFR_PY1173	5.53674322434482e-05	-0.214366731191558	0.00354351566358068	3
BID|BID	0.00115161716010439	-0.215126126035714	0.0147406996493362	3
WWTR1|TAZ	0.000404764098637021	-0.233370451694805	0.00863496743758978	3
RICTOR|RICTOR_PT1135	0.00124532744130205	-0.248100879168831	0.0149439292956246	3
EIF4EBP1|4E-BP1_PT70	0.00937368335603734	-0.252624013957792	0.0529337413046814	3
PDK1|PDK1	0.00354772885305801	-0.30265671837013	0.029921778790151	3
COL6A1|COLLAGEN_VI	0.00554555370250041	-0.308018215016234	0.0367153900303475	3
EIF4EBP1|4E-BP1	0.0016219256648176	-0.32138837112987	0.0183182192732341	3
STMN1|STATHMIN	9.10097917161103e-05	-0.337236031503247	0.00436847000237329	3
MYC|C-MYC	0.000793461108043244	-0.465650364461039	0.0115480989081392	3
MAP2K1|MEK1	0.00389606494663424	-0.468678417704545	0.029921778790151	3
NRG1|HEREGULIN	0.000842048878718485	-0.499724246227273	0.0115480989081392	3
CCND1|CYCLIN_D1	3.10886469590722e-05	-0.534871194405844	0.00298451010807093	3
HSPA1A|HSP70	0.00326664145339073	-0.606478752948052	0.0298664361452867	3
SERPINE1|PAI-1	0.0148477951029659	1.2236594771875	0.0863871715081652	5
HSPA1A|HSP70	0.000113704023588999	1.19537573372379	0.0167031419652665	5
RAD51|RAD51	0.0022717670455883	0.825719155058468	0.0545224090941192	5
MYC|C-MYC	0.0102894505919597	0.744538166905242	0.0790229805462505	5
CHEK2|CHK2_PT68	0.00512029160777866	0.48339761327621	0.0756227683610387	5
COL6A1|COLLAGEN_VI	0.00383188600013988	0.478855661034274	0.0735722112026857	5
CCND1|CYCLIN_D1	0.00132402823827993	0.476397364885081	0.0402551235878507	5
PECAM1|CD31	0.00499365397703549	0.473063730530242	0.0756227683610387	5
STK11|LKB1	0.00744375056822538	0.461321545699597	0.0773556613128104	5
BID|BID	0.00738083507981364	0.452412427856855	0.0773556613128104	5
MRE11A|MRE11	0.00874306306403272	0.4403534729375	0.0773556613128104	5
STMN1|STATHMIN	0.00845720002653107	0.435271339840726	0.0773556613128104	5
CASP7|CASPASE-7_CLEAVEDD198	0.024819406939763	0.428865676417339	0.105313723237586	5
CDH2|N-CADHERIN	0.00351165324036557	0.413992757207661	0.0735722112026857	5
YWHAB|14-3-3_BETA	0.0045964011389781	0.376705744493952	0.0756227683610387	5
ACVRL1|ACVRL1	0.00926656359476374	0.344557217191532	0.0773556613128104	5
EGFR|EGFR_PY1173	0.0231397468514137	0.33758080084879	0.105313723237586	5
MAP2K1|MEK1_PS217_S221	0.0239726832349631	0.317524411893145	0.105313723237586	5
NRAS|N-RAS	0.00687354795582788	0.313696887905242	0.0773556613128104	5
MET|C-MET_PY1235	0.0216208043789273	0.3124773423125	0.105313723237586	5
ARHI|ARHI	0.0174859421695015	0.30911902022379	0.0987441440160085	5
WWTR1|TAZ	0.00919839056212269	0.303622296453629	0.0773556613128104	5
PGR|PR	0.0257799218342008	0.292903139885081	0.105313723237586	5
BRCA2|BRCA2	0.00131013325147087	0.2893846773125	0.0402551235878507	5
RPS6KA1|P90RSK_PT359_S363	0.03731141034898	0.285603230631048	0.13110990692991	5
G6PD|G6PD	0.0285265477630698	0.2811612874375	0.111777493275702	5
RAB11A RAB11B|RAB11	0.0190463734423366	0.267890618429436	0.0988352351602332	5
RAF1|C-RAF_PS338	0.0416547100141902	0.256193307872984	0.13110990692991	5
FOXO3|FOXO3A	0.04066735180726	0.220684114905242	0.13110990692991	5
YWHAE|14-3-3_EPSILON	0.046749466259226	0.180227386784274	0.138090731104175	5
CDKN1B|P27_PT157	0.0493218791885404	0.148828016760081	0.141340310510444	5
JUN|C-JUN_PS73	0.0385439778830948	-0.239153141360887	0.13110990692991	5
SRC|SRC_PY416	0.0410461033613822	-0.265095051433468	0.13110990692991	5
BCL2|BCL-2	0.0383607079262283	-0.306528235409274	0.13110990692991	5
TSC2|TUBERIN_PT1462	0.0142067667795237	-0.318688101558468	0.0852406006771422	5
PRKCA |PKC-ALPHA	0.0245790513697332	-0.3581608313125	0.105313723237586	5
GSK3A GSK3B|GSK3-ALPHA-BETA	0.0378572444895643	-0.368249715699597	0.13110990692991	5
MSH2|MSH2	0.0119214696772662	-0.36948148115121	0.0852406006771422	5
FASN|FASN	0.0404235692146286	-0.374315165030242	0.13110990692991	5
FRAP1|MTOR_PS2448	0.0189326275970062	-0.376751396844758	0.0988352351602332	5
BCL2L11|BIM	0.0208459945282832	-0.391501656747984	0.105313723237586	5
EEF2K|EEF2K	0.0284390570503074	-0.398983428163306	0.111777493275702	5
BAD|BAD_PS112	0.0433682965026969	-0.399889979764113	0.13217004648441	5
CHEK1|CHK1	0.00918554603013778	-0.430615477635081	0.0773556613128104	5
EIF4G1|EIF4G	0.00127455106003559	-0.43971331215121	0.0402551235878507	5
MYH9|MYOSIN-IIA_PS1943	0.0184574935960562	-0.454639678864919	0.0988352351602332	5
GSK3A GSK3B|GSK3-ALPHA-BETA_PS21_S9	0.0129152954307059	-0.481763716441532	0.0852406006771422	5
ACACA ACACB|ACC_PS79	0.0398736069279322	-0.515767341784274	0.13110990692991	5
PRKCA |PKC-ALPHA_PS657	0.0429843151384363	-0.56879754622379	0.13217004648441	5
BAP1|BAP1-C-4	0.012249411767054	-0.581701776449597	0.0852406006771422	5
BRAF|B-RAF	0.0466029744342852	-0.599503582840726	0.138090731104175	5
SFRS1|SF2	0.0294921101472316	-0.604363824590726	0.112579866643538	5
TSC1|TSC1	0.0359297679329603	-0.651536171913306	0.13110990692991	5
RICTOR|RICTOR	0.000467278155346289	-0.681092596586694	0.0299058019421625	5
RB1|RB_PS807_S811	0.00146763471414039	-0.682471625127016	0.0402551235878507	5
RPS6|S6_PS235_S236	0.00605735988966365	-0.696845794256049	0.0773556613128104	5
TSC2|TUBERIN	0.0482968913281981	-0.7670876998125	0.140500047500213	5
YAP1|YAP_PS127	0.0140265085392127	-0.772874505429435	0.0852406006771422	5
MSH6|MSH6	0.0101318234366768	-0.796308078933468	0.0790229805462505	5
PKC|PKC-PAN_BETAII_PS660	0.0138481662255477	-0.811167851102823	0.0852406006771422	5
GSK3A GSK3B|GSK3_PS9	0.0253588843371985	-0.831482472272177	0.105313723237586	5
FRAP1|MTOR	0.0231451418585363	-0.849354047385081	0.105313723237586	5
TP53BP1|53BP1	0.0132095789099269	-0.853681282832661	0.0852406006771422	5
RBM15|RBM15	0.0220777163865535	-0.898320783727823	0.105313723237586	5
PTEN|PTEN	0.0299040270771897	-0.939833013828629	0.112579866643538	5
CTNNB2|BETA-CATENIN	0.008063152998402	-1.20603698942137	0.0773556613128104	5
CDH1|E-CADHERIN	0.000173991062138193	-1.64027196256653	0.0167031419652665	5