Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.114 0.168 0.333 21.0 -9999.0 0.0 21.0 KIRREL -0.043 0.138 -9999.0 0.0 -0.483 5.0 5.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.114 0.169 -9999.0 0.0 -0.334 21.0 21.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.08 0.138 -9999.0 0.0 -0.307 7.0 7.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.049 0.107 -9999.0 0.0 -0.259 7.0 7.0 FYN -0.076 0.125 -9999.0 0.0 -0.276 9.0 9.0 mol:Ca2+ -0.08 0.137 -9999.0 0.0 -0.304 7.0 7.0 mol:DAG -0.08 0.138 -9999.0 0.0 -0.305 7.0 7.0 NPHS2 -0.033 0.109 -9999.0 0.0 -0.486 3.0 3.0 mol:IP3 -0.08 0.138 -9999.0 0.0 -0.305 7.0 7.0 regulation of endocytosis -0.064 0.119 -9999.0 0.0 -0.305 4.0 4.0 Nephrin/NEPH1/podocin/Cholesterol -0.088 0.138 -9999.0 0.0 -0.253 22.0 22.0 establishment of cell polarity -0.114 0.168 -9999.0 0.0 -0.333 21.0 21.0 Nephrin/NEPH1/podocin/NCK1-2 -0.065 0.127 -9999.0 0.0 -0.414 2.0 2.0 Nephrin/NEPH1/beta Arrestin2 -0.064 0.121 -9999.0 0.0 -0.309 4.0 4.0 NPHS1 -0.129 0.213 -9999.0 0.0 -0.469 16.0 16.0 Nephrin/NEPH1/podocin -0.075 0.126 -9999.0 0.0 -0.278 9.0 9.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.08 0.138 -9999.0 0.0 -0.307 7.0 7.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.08 0.138 -9999.0 0.0 -0.292 9.0 9.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.096 0.15 -9999.0 0.0 -0.309 13.0 13.0 cytoskeleton organization -0.059 0.128 -9999.0 0.0 -0.329 5.0 5.0 Nephrin/NEPH1 -0.077 0.118 -9999.0 0.0 -0.23 21.0 21.0 Nephrin/NEPH1/ZO-1 -0.081 0.134 -9999.0 0.0 -0.255 21.0 21.0