Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.009	0.231	0.37	13.0	-0.463	10.0	23.0
IHH	0.056	0.09	0.219	11.0	-0.123	7.0	18.0
SHH Np/Cholesterol/GAS1	0.021	0.031	0.143	3.0	-0.156	1.0	4.0
LRPAP1	0.024	0.005	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	-0.021	0.031	0.155	1.0	-0.141	3.0	4.0
SMO/beta Arrestin2	0.026	0.151	0.348	2.0	-0.281	10.0	12.0
SMO	0.01	0.153	0.375	2.0	-0.29	10.0	12.0
AKT1	-0.016	0.122	-9999.0	0.0	-0.397	2.0	2.0
ARRB2	0.025	0.0	-9999.0	0.0	-9999.0	0.0	0.0
BOC	-0.004	0.092	0.237	1.0	-0.29	7.0	8.0
ADRBK1	0.025	0.004	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	0.011	0.152	0.374	2.0	-0.287	10.0	12.0
STIL	-0.001	0.119	0.268	3.0	-0.229	7.0	10.0
DHH N/PTCH2	0.026	0.053	0.184	2.0	-0.203	3.0	5.0
DHH N/PTCH1	0.031	0.141	0.255	9.0	-0.246	9.0	18.0
PIK3CA	0.013	0.049	-9999.0	0.0	-0.29	2.0	2.0
DHH	0.026	0.049	0.237	2.0	-0.29	1.0	3.0
PTHLH	-0.019	0.313	0.433	10.0	-0.703	10.0	20.0
determination of left/right symmetry	0.011	0.152	0.374	2.0	-0.287	10.0	12.0
PIK3R1	0.025	0.003	-9999.0	0.0	-9999.0	0.0	0.0
skeletal system development	-0.019	0.311	0.432	10.0	-0.696	10.0	20.0
IHH N/Hhip	0.044	0.085	0.23	4.0	-0.187	4.0	8.0
DHH N/Hhip	0.038	0.043	0.182	4.0	-0.203	1.0	5.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	0.011	0.152	0.374	2.0	-0.287	10.0	12.0
pancreas development	0.027	0.034	0.236	2.0	-9999.0	0.0	2.0
HHAT	0.024	0.006	-9999.0	0.0	-9999.0	0.0	0.0
PI3K	0.025	0.039	-9999.0	0.0	-0.203	2.0	2.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.027	0.049	0.237	2.0	-0.29	1.0	3.0
somite specification	0.011	0.152	0.374	2.0	-0.287	10.0	12.0
SHH Np/Cholesterol/PTCH1	0.011	0.123	0.213	12.0	-0.236	7.0	19.0
SHH Np/Cholesterol/PTCH2	0.012	0.031	0.127	1.0	-0.156	2.0	3.0
SHH Np/Cholesterol/Megalin	0.015	0.096	0.158	16.0	-0.154	14.0	30.0
SHH	-0.014	0.021	0.171	1.0	-9999.0	0.0	1.0
catabolic process	0.025	0.16	0.283	13.0	-0.274	9.0	22.0
SMO/Vitamin D3	0.02	0.152	0.263	11.0	-0.272	6.0	17.0
SHH Np/Cholesterol/Hhip	0.01	0.037	0.205	2.0	-9999.0	0.0	2.0
LRP2	0.014	0.169	0.237	18.0	-0.29	15.0	33.0
receptor-mediated endocytosis	0.001	0.172	0.285	10.0	-0.317	9.0	19.0
SHH Np/Cholesterol/BOC	0.003	0.053	0.139	2.0	-0.156	7.0	9.0
SHH Np/Cholesterol/CDO	0.019	0.014	0.127	1.0	-9999.0	0.0	1.0
mesenchymal cell differentiation	-0.009	0.037	-9999.0	0.0	-0.203	2.0	2.0
mol:Vitamin D3	0.016	0.145	0.249	14.0	-0.237	7.0	21.0
IHH N/PTCH2	0.029	0.084	0.167	1.0	-0.197	6.0	7.0
CDON	0.024	0.006	-9999.0	0.0	-9999.0	0.0	0.0
IHH N/PTCH1	0.037	0.169	0.307	13.0	-0.254	13.0	26.0
Megalin/LRPAP1	0.024	0.125	0.184	18.0	-0.203	15.0	33.0
PTCH2	0.014	0.049	-9999.0	0.0	-0.29	2.0	2.0
SHH Np/Cholesterol	-0.01	0.014	0.103	1.0	-9999.0	0.0	1.0
PTCH1	0.025	0.161	0.283	13.0	-0.275	9.0	22.0
HHIP	0.027	0.034	0.237	2.0	-9999.0	0.0	2.0