Correlation between gene mutation status and molecular subtypes

Overview

Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 171 genes and 14 molecular subtypes across 799 patients, 219 significant findings detected with P value < 0.05 and Q value < 0.25.

IDH1 mutation correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
TP53 mutation correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
ATRX mutation correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
CIC mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
NF1 mutation correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
PIK3R1 mutation correlated to 'METHLYATION_CNMF'.
NOTCH1 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
IDH2 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
PIK3CA mutation correlated to 'METHLYATION_CNMF' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
RB1 mutation correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
FUBP1 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
PTEN mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
STK19 mutation correlated to 'MIRSEQ_MATURE_CNMF'.
ARID1A mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
NIPBL mutation correlated to 'METHLYATION_CNMF'.
NUDT11 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
CREBZF mutation correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
SLC26A3 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
PLCG1 mutation correlated to 'CN_CNMF' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
SEMG1 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
NUP210L mutation correlated to 'METHLYATION_CNMF'.
PDGFRA mutation correlated to 'MRNA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
STAG2 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
REN mutation correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
MUC17 mutation correlated to 'MIRSEQ_CNMF' and 'MIRSEQ_MATURE_CNMF'.
RPL5 mutation correlated to 'METHLYATION_CNMF'.
BRAF mutation correlated to 'METHLYATION_CNMF'.
KDR mutation correlated to 'METHLYATION_CNMF'.
RBPJ mutation correlated to 'RPPA_CHIERARCHICAL'.
TRERF1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
PTPN11 mutation correlated to 'MIRSEQ_CHIERARCHICAL' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
FAM47C mutation correlated to 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
EGFR mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
ACADS mutation correlated to 'METHLYATION_CNMF'.
SRPX mutation correlated to 'MIRSEQ_MATURE_CHIERARCHICAL'.
WRN mutation correlated to 'MIRSEQ_MATURE_CNMF' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
KTELC1 mutation correlated to 'MIRSEQ_CHIERARCHICAL'.
SOX4 mutation correlated to 'MIRSEQ_CNMF'.
RASGRF2 mutation correlated to 'MIRSEQ_CHIERARCHICAL'.
FAM83D mutation correlated to 'MIRSEQ_CHIERARCHICAL'.
ATF7IP2 mutation correlated to 'MIRSEQ_CHIERARCHICAL' and 'MIRSEQ_MATURE_CNMF'.
ZBTB20 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
ZDHHC4 mutation correlated to 'METHLYATION_CNMF'.
EEF1A1 mutation correlated to 'CN_CNMF' and 'MIRSEQ_CNMF'.
PROKR2 mutation correlated to 'CN_CNMF'.
PRCP mutation correlated to 'METHLYATION_CNMF'.
POM121 mutation correlated to 'CN_CNMF'.
AOX1 mutation correlated to 'MRNASEQ_CNMF'.
CDKN2A mutation correlated to 'MIRSEQ_CNMF'.
SMARCA4 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
DOCK5 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
GRHL3 mutation correlated to 'MIRSEQ_CHIERARCHICAL'.
FMR1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
CD209 mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
TNFRSF9 mutation correlated to 'METHLYATION_CNMF'.
MYT1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
DLC1 mutation correlated to 'MIRSEQ_MATURE_CHIERARCHICAL'.
TMPRSS6 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
MAP3K1 mutation correlated to 'MRNASEQ_CNMF'.
PASD1 mutation correlated to 'MIR_CHIERARCHICAL'.
TJAP1 mutation correlated to 'METHLYATION_CNMF'.
GABRA6 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
ALPK3 mutation correlated to 'METHLYATION_CNMF'.
ST3GAL6 mutation correlated to 'RPPA_CHIERARCHICAL'.
SOX13 mutation correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
NKX2-2 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
WDR90 mutation correlated to 'MIR_CNMF'.
TP63 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
AK7 mutation correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
DSP mutation correlated to 'CN_CNMF' and 'MIRSEQ_CHIERARCHICAL'.
FBN3 mutation correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
SEZ6L2 mutation correlated to 'RPPA_CNMF' and 'RPPA_CHIERARCHICAL'.
IGFN1 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_CHIERARCHICAL'.

Results

Overview of the results

Table 1. Get Full Table Overview of the association between mutation status of 171 genes and 14 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 219 significant findings detected.


		Clinical Features	MRNA CNMF	MRNA CHIERARCHICAL	MIR CNMF	MIR CHIERARCHICAL	CN CNMF	METHLYATION CNMF	RPPA CNMF	RPPA CHIERARCHICAL	MRNASEQ CNMF	MRNASEQ CHIERARCHICAL	MIRSEQ CNMF	MIRSEQ CHIERARCHICAL	MIRSEQ MATURE CNMF	MIRSEQ MATURE CHIERARCHICAL
	nMutated (%)	nWild-Type	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test
IDH1	415 (52%)	384	0.00019 (0.00535)	1e-05 (0.000413)	5e-05 (0.00173)	0.00288 (0.0621)	1e-05 (0.000413)	1e-05 (0.000413)	0.00389 (0.0776)	0.12 (0.65)	1e-05 (0.000413)	1e-05 (0.000413)	0.00011 (0.00338)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)
ATRX	214 (27%)	585	0.00355 (0.0726)	1e-05 (0.000413)	0.0158 (0.196)	0.0185 (0.214)	1e-05 (0.000413)	1e-05 (0.000413)	0.00642 (0.112)	0.738 (1.00)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)	2e-05 (0.00076)	1e-05 (0.000413)	1e-05 (0.000413)
TP53	331 (41%)	468	0.00071 (0.0181)	2e-05 (0.00076)	0.00108 (0.0251)	0.205 (0.843)	1e-05 (0.000413)	1e-05 (0.000413)	0.115 (0.636)	0.00942 (0.138)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)	3e-05 (0.00109)	1e-05 (0.000413)	1e-05 (0.000413)
CIC	109 (14%)	690					1e-05 (0.000413)	1e-05 (0.000413)	0.00566 (0.102)	0.264 (0.908)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)
EGFR	109 (14%)	690	0.0858 (0.542)	0.0565 (0.436)	0.277 (0.916)	0.138 (0.703)	1e-05 (0.000413)	1e-05 (0.000413)	0.313 (0.943)	0.0189 (0.217)	1e-05 (0.000413)	1e-05 (0.000413)	0.0112 (0.159)	1e-05 (0.000413)	9e-05 (0.00291)	1e-05 (0.000413)
NF1	62 (8%)	737	0.103 (0.605)	0.0004 (0.0108)	0.0335 (0.317)	0.932 (1.00)	0.00015 (0.00438)	1e-05 (0.000413)	0.662 (1.00)	4e-05 (0.00141)	0.00029 (0.00798)	0.00162 (0.0366)	0.359 (0.997)	0.00013 (0.00394)	0.356 (0.996)	2e-05 (0.00076)
NOTCH1	42 (5%)	757					1e-05 (0.000413)	1e-05 (0.000413)	0.733 (1.00)	1 (1.00)	1e-05 (0.000413)	1e-05 (0.000413)	0.00016 (0.00461)	0.00496 (0.0928)	1e-05 (0.000413)	0.0046 (0.0888)
FUBP1	47 (6%)	752					1e-05 (0.000413)	1e-05 (0.000413)	0.16 (0.757)	0.426 (1.00)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)	0.00104 (0.0249)	8e-05 (0.00266)	1e-05 (0.000413)
PTEN	111 (14%)	688	0.151 (0.729)	0.0753 (0.5)	0.0449 (0.394)	0.647 (1.00)	1e-05 (0.000413)	1e-05 (0.000413)	0.705 (1.00)	0.113 (0.636)	1e-05 (0.000413)	1e-05 (0.000413)	0.00411 (0.0813)	1e-05 (0.000413)	0.00035 (0.00952)	1e-05 (0.000413)
IDH2	20 (3%)	779					0.00065 (0.0169)	0.00011 (0.00338)	0.199 (0.832)	0.135 (0.7)	2e-05 (0.00076)	2e-05 (0.00076)	0.00869 (0.132)	0.00075 (0.0189)	0.0392 (0.356)	0.0665 (0.472)
ZBTB20	22 (3%)	777					0.00101 (0.0244)	0.00015 (0.00438)	0.655 (1.00)	0.0938 (0.571)	0.00015 (0.00438)	3e-05 (0.00109)	0.143 (0.709)	0.021 (0.235)	0.0138 (0.181)	0.145 (0.712)
RB1	30 (4%)	769	0.0845 (0.538)	0.0176 (0.21)	0.104 (0.608)	0.922 (1.00)	1e-05 (0.000413)	3e-05 (0.00109)	0.308 (0.943)	0.179 (0.821)	0.00011 (0.00338)	7e-05 (0.00236)	0.6 (1.00)	0.0341 (0.321)	0.703 (1.00)	0.094 (0.571)
ARID1A	22 (3%)	777					0.0138 (0.181)	0.0156 (0.195)	0.244 (0.894)	1 (1.00)	0.0139 (0.181)	0.00607 (0.108)	0.519 (1.00)	0.604 (1.00)	0.00486 (0.0916)	0.0615 (0.456)
PDGFRA	21 (3%)	778	0.00923 (0.137)	0.148 (0.719)	1 (1.00)	0.139 (0.704)	0.216 (0.866)	0.274 (0.908)	0.22 (0.872)	0.00797 (0.126)	0.00106 (0.0251)	0.0239 (0.257)	0.00067 (0.0172)	0.00141 (0.0325)	0.898 (1.00)	0.0562 (0.435)
STAG2	16 (2%)	783	0.493 (1.00)	0.697 (1.00)	0.522 (1.00)	0.59 (1.00)	0.00023 (0.0064)	6e-05 (0.00205)	0.355 (0.996)	0.0599 (0.448)	0.00045 (0.012)	0.00108 (0.0251)	0.54 (1.00)	0.0134 (0.18)	0.907 (1.00)	0.298 (0.94)
SMARCA4	27 (3%)	772					0.00095 (0.0234)	0.00579 (0.103)	0.535 (1.00)	0.799 (1.00)	0.0143 (0.183)	0.00934 (0.138)	0.31 (0.943)	0.243 (0.89)	0.0216 (0.239)	0.18 (0.825)
SLC26A3	11 (1%)	788	0.845 (1.00)	0.768 (1.00)	0.58 (1.00)	0.363 (1.00)	0.0038 (0.0764)	0.0153 (0.192)	0.072 (0.484)	0.0648 (0.465)	0.0119 (0.168)	0.00566 (0.102)	0.0442 (0.39)	0.0272 (0.282)	1 (1.00)	0.218 (0.87)
SEMG1	11 (1%)	788	0.959 (1.00)	0.177 (0.818)	0.957 (1.00)	1 (1.00)	0.00011 (0.00338)	0.00962 (0.14)	0.413 (1.00)	0.787 (1.00)	0.00445 (0.0866)	0.00888 (0.134)	0.155 (0.739)	0.152 (0.732)	0.378 (1.00)	0.592 (1.00)
DOCK5	20 (3%)	779	0.366 (1.00)	0.907 (1.00)	0.214 (0.862)	0.301 (0.94)	0.0133 (0.18)	0.00993 (0.144)	0.186 (0.83)	0.166 (0.779)	0.00372 (0.0755)	0.00527 (0.097)	0.0354 (0.329)	0.0595 (0.448)	0.388 (1.00)	0.188 (0.83)
TMPRSS6	9 (1%)	790	0.732 (1.00)	0.702 (1.00)	0.726 (1.00)	0.264 (0.908)	0.00759 (0.123)	0.0149 (0.188)	0.488 (1.00)	0.116 (0.636)	0.00471 (0.0895)	0.00726 (0.119)	0.155 (0.738)	0.153 (0.734)	0.436 (1.00)	0.591 (1.00)
GABRA6	15 (2%)	784	0.0495 (0.413)	0.533 (1.00)	0.168 (0.782)	0.112 (0.636)	0.00048 (0.0126)	0.0085 (0.131)	0.825 (1.00)	0.924 (1.00)	0.00247 (0.0542)	0.0922 (0.566)	0.54 (1.00)	0.0132 (0.18)	0.908 (1.00)	0.856 (1.00)
AK7	9 (1%)	790	0.0975 (0.587)	0.127 (0.672)	0.628 (1.00)	0.235 (0.886)	0.0127 (0.177)	0.0574 (0.441)	0.72 (1.00)	0.496 (1.00)	0.0167 (0.205)	0.0863 (0.542)	0.0683 (0.479)	0.00151 (0.0344)	0.161 (0.76)	0.00717 (0.118)
CREBZF	9 (1%)	790					0.0243 (0.26)	0.00017 (0.00484)	0.0259 (0.272)	0.429 (1.00)	0.0105 (0.15)	0.068 (0.479)	0.178 (0.819)	0.0136 (0.181)	0.267 (0.908)	0.294 (0.936)
FAM47C	24 (3%)	775	0.302 (0.94)	0.0583 (0.445)	0.349 (0.992)	0.843 (1.00)	0.571 (1.00)	0.561 (1.00)	0.794 (1.00)	0.562 (1.00)	0.0757 (0.5)	0.00306 (0.0637)	0.437 (1.00)	0.0621 (0.456)	0.00097 (0.0237)	0.00523 (0.097)
IGFN1	9 (1%)	790	1 (1.00)	1 (1.00)	0.726 (1.00)	0.559 (1.00)	0.0146 (0.186)	0.00295 (0.0631)	0.874 (1.00)	0.641 (1.00)	0.0316 (0.306)	0.19 (0.83)	1 (1.00)	0.00841 (0.131)	0.559 (1.00)	0.0728 (0.487)
PIK3CA	71 (9%)	728	0.92 (1.00)	0.288 (0.93)	0.275 (0.911)	0.861 (1.00)	1 (1.00)	1e-05 (0.000413)	0.29 (0.933)	0.377 (1.00)	0.598 (1.00)	0.0392 (0.356)	0.0274 (0.283)	0.0373 (0.344)	0.206 (0.844)	1e-05 (0.000413)
PLCG1	11 (1%)	788	0.765 (1.00)	0.927 (1.00)	0.816 (1.00)	0.842 (1.00)	0.0192 (0.219)	0.262 (0.906)	0.233 (0.886)	1 (1.00)	0.636 (1.00)	0.272 (0.908)	0.0313 (0.306)	0.0645 (0.464)	0.0459 (0.398)	0.0215 (0.239)
REN	7 (1%)	792	0.302 (0.94)	0.415 (1.00)	0.0706 (0.484)	0.511 (1.00)	0.00336 (0.0693)	0.00256 (0.0557)	0.851 (1.00)	0.885 (1.00)	0.295 (0.936)	0.783 (1.00)
MUC17	50 (6%)	749	0.0638 (0.463)	0.192 (0.83)	0.802 (1.00)	0.702 (1.00)	0.379 (1.00)	0.497 (1.00)	0.205 (0.843)	0.371 (1.00)	0.0399 (0.359)	0.179 (0.821)	0.0201 (0.228)	0.0323 (0.309)	0.0067 (0.114)	0.685 (1.00)
PTPN11	11 (1%)	788	1 (1.00)	0.787 (1.00)	0.132 (0.691)	1 (1.00)	0.516 (1.00)	0.0788 (0.512)	0.388 (1.00)	0.231 (0.886)	0.302 (0.94)	0.266 (0.908)	0.233 (0.886)	0.00541 (0.0989)	0.184 (0.83)	0.00178 (0.0398)
WRN	6 (1%)	793					1 (1.00)	0.0464 (0.4)	0.874 (1.00)	0.64 (1.00)	1 (1.00)	0.518 (1.00)	0.0576 (0.441)	1 (1.00)	0.0112 (0.159)	0.00471 (0.0895)
ATF7IP2	8 (1%)	791	0.916 (1.00)	1 (1.00)	0.326 (0.968)	0.105 (0.609)	0.0389 (0.356)	0.353 (0.996)	0.634 (1.00)	1 (1.00)	0.0384 (0.354)	0.102 (0.602)	1 (1.00)	0.00793 (0.126)	0.021 (0.235)	0.097 (0.585)
EEF1A1	8 (1%)	791	0.238 (0.888)	0.192 (0.83)	0.642 (1.00)	0.444 (1.00)	0.014 (0.182)	0.368 (1.00)	0.0521 (0.414)	0.686 (1.00)	0.251 (0.902)	0.444 (1.00)	0.0219 (0.241)	0.194 (0.83)	0.676 (1.00)	0.503 (1.00)
CD209	10 (1%)	789	0.832 (1.00)	1 (1.00)	0.327 (0.969)	0.609 (1.00)	0.0865 (0.542)	0.102 (0.602)	0.031 (0.304)	0.319 (0.952)	0.141 (0.707)	0.0165 (0.203)	0.208 (0.849)	0.116 (0.636)	0.38 (1.00)	0.00301 (0.0632)
SOX13	5 (1%)	794			0.778 (1.00)	1 (1.00)	0.0143 (0.183)	0.0102 (0.147)	0.416 (1.00)	1 (1.00)	0.515 (1.00)	1 (1.00)
DSP	21 (3%)	778	0.318 (0.95)	0.962 (1.00)	0.658 (1.00)	0.0713 (0.484)	0.0086 (0.131)	0.088 (0.547)	0.448 (1.00)	0.586 (1.00)	0.725 (1.00)	0.669 (1.00)	0.734 (1.00)	0.0168 (0.205)	0.637 (1.00)	0.237 (0.886)
FBN3	18 (2%)	781	0.346 (0.989)	0.31 (0.943)	1 (1.00)	0.921 (1.00)	0.00795 (0.126)	0.0139 (0.181)	0.638 (1.00)	0.935 (1.00)	0.0557 (0.433)	0.111 (0.629)	0.711 (1.00)	0.0545 (0.425)	0.429 (1.00)	0.285 (0.93)
SEZ6L2	7 (1%)	792	0.355 (0.996)	0.47 (1.00)	0.491 (1.00)	0.123 (0.658)	0.688 (1.00)	0.826 (1.00)	0.0182 (0.213)	0.00429 (0.0842)	0.204 (0.843)	1 (1.00)	0.24 (0.888)	0.0987 (0.592)	0.0651 (0.466)	0.183 (0.83)
PIK3R1	54 (7%)	745	0.414 (1.00)	0.193 (0.83)	0.0616 (0.456)	0.529 (1.00)	0.0917 (0.566)	9e-05 (0.00291)	0.849 (1.00)	0.919 (1.00)	0.184 (0.83)	0.927 (1.00)	0.0901 (0.559)	0.582 (1.00)	0.905 (1.00)	0.7 (1.00)
STK19	11 (1%)	788					0.903 (1.00)	0.681 (1.00)	0.424 (1.00)	0.632 (1.00)	0.382 (1.00)	0.863 (1.00)	0.157 (0.742)	0.542 (1.00)	0.00651 (0.113)	0.723 (1.00)
NIPBL	20 (3%)	779					0.199 (0.832)	4e-05 (0.00141)	0.647 (1.00)	0.57 (1.00)	0.0336 (0.317)	0.0494 (0.413)	0.451 (1.00)	0.171 (0.795)	0.031 (0.304)	0.035 (0.327)
NUDT11	11 (1%)	788					0.123 (0.658)	0.262 (0.906)	0.79 (1.00)	0.295 (0.936)	0.325 (0.968)	0.0147 (0.187)	0.027 (0.281)	0.919 (1.00)	0.553 (1.00)	0.223 (0.88)
NUP210L	12 (2%)	787	0.635 (1.00)	0.426 (1.00)	0.327 (0.969)	0.355 (0.996)	0.0627 (0.459)	0.00685 (0.115)	0.4 (1.00)	1 (1.00)	0.0303 (0.302)	0.207 (0.848)	0.399 (1.00)	0.0756 (0.5)	0.288 (0.93)	0.68 (1.00)
RPL5	10 (1%)	789	0.39 (1.00)	0.508 (1.00)	0.908 (1.00)	0.469 (1.00)	0.0503 (0.414)	0.012 (0.168)	0.49 (1.00)	0.801 (1.00)	0.0323 (0.309)	0.187 (0.83)	0.0712 (0.484)	0.0524 (0.414)	0.794 (1.00)	0.133 (0.691)
BRAF	11 (1%)	788	0.594 (1.00)	0.71 (1.00)	0.317 (0.949)	0.0287 (0.293)	0.137 (0.7)	0.00085 (0.0212)	0.833 (1.00)	0.287 (0.93)	0.0722 (0.484)	0.359 (0.996)	0.262 (0.906)	0.091 (0.563)	0.126 (0.669)	0.44 (1.00)
KDR	13 (2%)	786	0.22 (0.872)	0.655 (1.00)	0.245 (0.897)	0.513 (1.00)	0.0459 (0.398)	0.00784 (0.126)	0.87 (1.00)	0.0953 (0.576)	0.144 (0.711)	0.671 (1.00)	0.262 (0.906)	0.0233 (0.253)	0.288 (0.93)	0.336 (0.983)
RBPJ	7 (1%)	792					0.0659 (0.47)	0.0454 (0.397)	0.268 (0.908)	0.00714 (0.118)	0.032 (0.309)	0.144 (0.711)	0.305 (0.941)	0.0287 (0.293)	0.377 (1.00)	0.231 (0.886)
TRERF1	7 (1%)	792					0.581 (1.00)	0.579 (1.00)	0.377 (1.00)	0.774 (1.00)	1 (1.00)	0.0185 (0.214)	0.371 (1.00)	0.759 (1.00)	0.358 (0.996)	0.91 (1.00)
ACADS	5 (1%)	794	0.62 (1.00)	0.349 (0.992)	0.28 (0.922)	0.791 (1.00)	0.147 (0.719)	0.018 (0.213)
SRPX	4 (1%)	795					1 (1.00)	0.215 (0.864)	0.431 (1.00)	0.682 (1.00)	0.56 (1.00)	0.569 (1.00)	0.338 (0.983)	0.195 (0.83)	0.453 (1.00)	0.00856 (0.131)
KTELC1	5 (1%)	794					0.199 (0.832)	0.317 (0.949)	0.469 (1.00)	0.376 (1.00)	0.539 (1.00)	0.193 (0.83)	0.117 (0.638)	0.0067 (0.114)	0.93 (1.00)	0.502 (1.00)
SOX4	7 (1%)	792					1 (1.00)	0.272 (0.908)	0.914 (1.00)	0.457 (1.00)	0.187 (0.83)	0.652 (1.00)	0.00641 (0.112)	0.12 (0.65)	0.0523 (0.414)	0.0303 (0.302)
RASGRF2	6 (1%)	793					0.418 (1.00)	0.183 (0.83)	0.917 (1.00)	1 (1.00)	0.39 (1.00)	0.67 (1.00)	0.069 (0.48)	0.0134 (0.18)	0.489 (1.00)	0.0413 (0.37)
FAM83D	6 (1%)	793					0.422 (1.00)	0.183 (0.83)	0.599 (1.00)	0.68 (1.00)	0.634 (1.00)	0.62 (1.00)	0.536 (1.00)	0.0138 (0.181)	0.783 (1.00)	0.0415 (0.371)
ZDHHC4	4 (1%)	795			0.236 (0.886)	1 (1.00)	0.0703 (0.484)	0.009 (0.135)	1 (1.00)	0.626 (1.00)
PROKR2	9 (1%)	790	0.497 (1.00)	0.727 (1.00)	0.487 (1.00)	0.184 (0.83)	0.0128 (0.177)	0.241 (0.889)	0.252 (0.902)	0.483 (1.00)	0.101 (0.602)	0.0368 (0.341)	0.237 (0.886)	0.794 (1.00)	1 (1.00)	0.428 (1.00)
PRCP	5 (1%)	794					0.501 (1.00)	0.0175 (0.21)	1 (1.00)	0.267 (0.908)	0.514 (1.00)	0.487 (1.00)
POM121	6 (1%)	793					0.00686 (0.115)	0.354 (0.996)	0.465 (1.00)	0.141 (0.707)	0.632 (1.00)	0.617 (1.00)	0.54 (1.00)	0.339 (0.983)	0.784 (1.00)	0.971 (1.00)
AOX1	8 (1%)	791	0.327 (0.969)	0.278 (0.918)	0.763 (1.00)	0.185 (0.83)	0.115 (0.636)	0.482 (1.00)	0.578 (1.00)	0.886 (1.00)	0.00663 (0.114)	0.105 (0.609)	0.0442 (0.39)	0.0277 (0.285)	0.674 (1.00)	0.273 (0.908)
CDKN2A	6 (1%)	793					0.813 (1.00)	1 (1.00)	0.65 (1.00)	0.682 (1.00)	0.293 (0.935)	0.388 (1.00)	0.0221 (0.243)	0.262 (0.906)	0.49 (1.00)	0.241 (0.888)
GRHL3	8 (1%)	791	0.912 (1.00)	1 (1.00)	1 (1.00)	0.445 (1.00)	0.0394 (0.356)	0.0863 (0.542)	0.931 (1.00)	0.643 (1.00)	0.0321 (0.309)	0.442 (1.00)	0.541 (1.00)	0.0132 (0.18)	0.287 (0.93)	0.297 (0.938)
FMR1	5 (1%)	794					0.77 (1.00)	0.261 (0.906)	0.596 (1.00)	1 (1.00)	0.389 (1.00)	0.00194 (0.043)	0.24 (0.888)	0.358 (0.996)	0.733 (1.00)	0.313 (0.943)
TNFRSF9	4 (1%)	795					0.391 (1.00)	0.003 (0.0632)	1 (1.00)	0.569 (1.00)	1 (1.00)	1 (1.00)	0.679 (1.00)	0.793 (1.00)	0.439 (1.00)	0.867 (1.00)
MYT1	6 (1%)	793					0.641 (1.00)	0.22 (0.872)			0.777 (1.00)	0.0183 (0.214)	0.41 (1.00)	0.757 (1.00)	0.854 (1.00)	0.95 (1.00)
DLC1	9 (1%)	790	1 (1.00)	0.0589 (0.448)	0.394 (1.00)	0.194 (0.83)	0.114 (0.636)	0.317 (0.949)	0.777 (1.00)	1 (1.00)	0.403 (1.00)	0.249 (0.9)	0.891 (1.00)	0.147 (0.719)	0.642 (1.00)	0.00748 (0.122)
MAP3K1	9 (1%)	790	0.929 (1.00)	0.729 (1.00)	0.763 (1.00)	0.648 (1.00)	0.0711 (0.484)	0.489 (1.00)	0.219 (0.87)	0.452 (1.00)	0.017 (0.207)	0.269 (0.908)	0.285 (0.93)	0.0517 (0.414)	0.561 (1.00)	0.225 (0.885)
PASD1	8 (1%)	791			0.194 (0.83)	0.00839 (0.131)	0.856 (1.00)	0.463 (1.00)	1 (1.00)	0.898 (1.00)	0.33 (0.972)	0.313 (0.943)	0.914 (1.00)	0.42 (1.00)	0.259 (0.906)	0.496 (1.00)
TJAP1	3 (0%)	796					0.0505 (0.414)	0.0171 (0.207)
ALPK3	4 (1%)	795					0.503 (1.00)	0.0173 (0.208)	0.787 (1.00)	1 (1.00)
ST3GAL6	5 (1%)	794					0.246 (0.897)	0.23 (0.886)	0.644 (1.00)	0.0206 (0.232)	0.0829 (0.532)	0.523 (1.00)	1 (1.00)	0.0519 (0.414)	0.629 (1.00)	0.132 (0.691)
NKX2-2	6 (1%)	793					0.642 (1.00)	0.896 (1.00)	0.551 (1.00)	0.886 (1.00)	0.338 (0.983)	0.0182 (0.213)	0.802 (1.00)	1 (1.00)	0.853 (1.00)	0.73 (1.00)
WDR90	9 (1%)	790	0.0775 (0.506)	0.365 (1.00)	0.0197 (0.225)	0.558 (1.00)	0.256 (0.906)	0.418 (1.00)	0.471 (1.00)	0.115 (0.636)	0.0734 (0.488)	0.39 (1.00)	0.521 (1.00)	0.79 (1.00)	0.49 (1.00)	0.675 (1.00)
TP63	10 (1%)	789	0.929 (1.00)	0.729 (1.00)	0.317 (0.949)	0.648 (1.00)	0.34 (0.983)	0.0495 (0.413)	0.0245 (0.26)	0.141 (0.707)	0.142 (0.707)	0.0224 (0.245)	0.335 (0.983)	0.264 (0.908)	0.0685 (0.479)	0.137 (0.7)
TCF12	19 (2%)	780	1 (1.00)	0.481 (1.00)	0.588 (1.00)	0.259 (0.906)	0.134 (0.692)	0.423 (1.00)	0.558 (1.00)	0.383 (1.00)	0.0835 (0.534)	0.294 (0.936)	0.854 (1.00)	0.516 (1.00)	0.0792 (0.514)	0.36 (0.998)
ZMIZ1	13 (2%)	786	0.649 (1.00)	0.911 (1.00)	0.538 (1.00)	0.445 (1.00)	0.195 (0.83)	0.25 (0.901)	0.11 (0.628)	0.118 (0.643)	0.749 (1.00)	0.346 (0.989)	0.444 (1.00)	0.677 (1.00)	0.0872 (0.545)	0.136 (0.7)
GAGE2A	8 (1%)	791					0.296 (0.938)	0.624 (1.00)	0.684 (1.00)	0.289 (0.932)	0.827 (1.00)	0.609 (1.00)	0.655 (1.00)	0.901 (1.00)	0.167 (0.782)	0.685 (1.00)
MED9	3 (0%)	796					0.269 (0.908)	0.674 (1.00)	0.205 (0.843)	0.267 (0.908)	0.202 (0.84)	1 (1.00)	0.877 (1.00)	0.791 (1.00)	1 (1.00)	0.767 (1.00)
NKD2	4 (1%)	795					0.75 (1.00)	1 (1.00)			0.271 (0.908)	1 (1.00)	0.302 (0.94)	1 (1.00)	1 (1.00)	0.694 (1.00)
IRS4	11 (1%)	788	0.701 (1.00)	1 (1.00)	0.281 (0.922)	0.123 (0.658)	1 (1.00)	0.824 (1.00)	0.661 (1.00)	0.477 (1.00)	0.516 (1.00)	0.136 (0.7)	0.199 (0.832)	0.383 (1.00)	0.233 (0.886)	0.563 (1.00)
HTRA2	5 (1%)	794					0.195 (0.83)	0.579 (1.00)	0.466 (1.00)	0.837 (1.00)	0.745 (1.00)	0.87 (1.00)	0.347 (0.989)	0.726 (1.00)	0.674 (1.00)	0.743 (1.00)
NRAS	5 (1%)	794					0.773 (1.00)	0.24 (0.888)	0.0506 (0.414)	0.851 (1.00)	0.0717 (0.484)	0.313 (0.943)	0.172 (0.796)	0.683 (1.00)	0.782 (1.00)	0.495 (1.00)
BCOR	22 (3%)	777	0.586 (1.00)	0.358 (0.996)	0.105 (0.609)	0.607 (1.00)	0.472 (1.00)	0.493 (1.00)	0.304 (0.94)	0.888 (1.00)	0.304 (0.94)	0.364 (1.00)	0.793 (1.00)	0.583 (1.00)	0.312 (0.943)	0.395 (1.00)
MX2	9 (1%)	790	0.549 (1.00)	0.839 (1.00)	0.331 (0.974)	0.443 (1.00)	0.252 (0.902)	0.657 (1.00)	0.895 (1.00)	0.402 (1.00)	0.839 (1.00)	1 (1.00)	0.306 (0.942)	1 (1.00)	0.671 (1.00)	0.53 (1.00)
DDX5	9 (1%)	790	0.412 (1.00)	1 (1.00)	0.646 (1.00)	0.444 (1.00)	1 (1.00)	0.602 (1.00)	0.644 (1.00)	0.562 (1.00)	0.778 (1.00)	0.594 (1.00)	0.261 (0.906)	0.524 (1.00)	0.653 (1.00)	0.293 (0.935)
SETD2	13 (2%)	786	0.106 (0.61)	0.35 (0.993)	0.391 (1.00)	1 (1.00)	0.0856 (0.542)	0.35 (0.993)	0.872 (1.00)	0.523 (1.00)	0.0677 (0.478)	0.381 (1.00)	0.365 (1.00)	0.0919 (0.566)	0.256 (0.906)	0.809 (1.00)
ZNF709	5 (1%)	794					1 (1.00)	0.191 (0.83)	0.548 (1.00)	0.572 (1.00)	0.687 (1.00)	1 (1.00)	0.878 (1.00)	0.601 (1.00)	0.434 (1.00)	0.565 (1.00)
FAM126B	8 (1%)	791	0.241 (0.888)	0.0298 (0.302)	0.586 (1.00)	0.447 (1.00)	0.142 (0.707)	0.757 (1.00)	0.505 (1.00)	0.771 (1.00)	0.4 (1.00)	0.695 (1.00)	0.197 (0.832)	0.196 (0.83)	0.575 (1.00)	0.649 (1.00)
MYST4	12 (2%)	787					0.254 (0.904)	0.0608 (0.454)	0.126 (0.669)	0.279 (0.918)	0.353 (0.996)	0.219 (0.87)	0.184 (0.83)	1 (1.00)	0.0721 (0.484)	0.759 (1.00)
TLR6	8 (1%)	791	0.128 (0.673)	0.0477 (0.405)	0.488 (1.00)	0.291 (0.933)	0.114 (0.636)	0.0243 (0.26)	1 (1.00)	1 (1.00)	0.463 (1.00)	0.569 (1.00)	0.237 (0.886)	0.231 (0.886)	0.63 (1.00)	0.448 (1.00)
TNRC18	12 (2%)	787					0.466 (1.00)	0.436 (1.00)	0.513 (1.00)	0.589 (1.00)	0.314 (0.945)	0.62 (1.00)	0.536 (1.00)	0.542 (1.00)	0.357 (0.996)	0.796 (1.00)
SLC6A3	12 (2%)	787	0.474 (1.00)	0.701 (1.00)	0.455 (1.00)	1 (1.00)	0.37 (1.00)	0.743 (1.00)	0.133 (0.691)	0.064 (0.463)	0.924 (1.00)	0.728 (1.00)	0.183 (0.83)	0.504 (1.00)	0.791 (1.00)	0.217 (0.867)
ZNF292	17 (2%)	782	0.299 (0.94)	0.223 (0.88)	0.455 (1.00)	0.311 (0.943)	0.238 (0.888)	0.144 (0.711)	0.427 (1.00)	0.802 (1.00)	0.131 (0.686)	0.0855 (0.542)	0.399 (1.00)	0.31 (0.943)	0.156 (0.741)	0.0466 (0.4)
ARID2	13 (2%)	786					0.617 (1.00)	0.82 (1.00)	0.865 (1.00)	0.61 (1.00)	1 (1.00)	0.132 (0.69)	0.593 (1.00)	0.344 (0.987)	0.835 (1.00)	0.935 (1.00)
KRTAP5-3	4 (1%)	795					1 (1.00)	0.354 (0.996)	0.267 (0.908)	0.837 (1.00)	0.396 (1.00)	0.103 (0.605)	0.0507 (0.414)	0.427 (1.00)
NEU2	9 (1%)	790	0.411 (1.00)	0.554 (1.00)	0.779 (1.00)	1 (1.00)	0.658 (1.00)	0.898 (1.00)	0.839 (1.00)	0.497 (1.00)	0.607 (1.00)	0.228 (0.886)	0.256 (0.906)	0.758 (1.00)	0.445 (1.00)	0.249 (0.9)
TMEM216	3 (0%)	796					0.436 (1.00)	0.863 (1.00)	0.872 (1.00)	0.19 (0.83)	0.201 (0.838)	0.638 (1.00)	0.523 (1.00)	0.6 (1.00)	0.377 (1.00)	0.906 (1.00)
ZNF41	8 (1%)	791					0.357 (0.996)	0.767 (1.00)	0.817 (1.00)	1 (1.00)	1 (1.00)	0.776 (1.00)	0.803 (1.00)	0.755 (1.00)	0.115 (0.636)	0.629 (1.00)
SERPING1	4 (1%)	795					1 (1.00)	0.904 (1.00)	0.703 (1.00)	0.139 (0.704)	0.202 (0.84)	0.636 (1.00)	0.596 (1.00)	0.601 (1.00)	0.632 (1.00)	0.834 (1.00)
ZNF512B	5 (1%)	794					0.771 (1.00)	0.81 (1.00)	0.633 (1.00)	1 (1.00)	0.745 (1.00)	0.338 (0.983)	1 (1.00)	1 (1.00)	0.467 (1.00)	0.759 (1.00)
TPX2	7 (1%)	792					1 (1.00)	0.532 (1.00)	0.834 (1.00)	1 (1.00)	1 (1.00)	0.591 (1.00)	0.491 (1.00)	0.0696 (0.483)	0.0947 (0.574)	0.465 (1.00)
C10ORF76	4 (1%)	795					0.502 (1.00)	0.0645 (0.464)			0.211 (0.851)	0.823 (1.00)	0.283 (0.929)	0.053 (0.417)	0.561 (1.00)	0.769 (1.00)
TRPV6	13 (2%)	786	0.575 (1.00)	0.228 (0.886)	0.27 (0.908)	1 (1.00)	0.223 (0.88)	0.482 (1.00)	0.894 (1.00)	0.43 (1.00)	0.0998 (0.596)	0.509 (1.00)	0.634 (1.00)	0.504 (1.00)	0.594 (1.00)	0.939 (1.00)
PDHA1	6 (1%)	793					0.333 (0.978)	0.448 (1.00)	0.894 (1.00)	0.299 (0.94)	0.777 (1.00)	0.884 (1.00)	0.929 (1.00)	0.847 (1.00)	0.872 (1.00)	0.0937 (0.571)
FAM123C	11 (1%)	788	0.0326 (0.31)	0.558 (1.00)	0.84 (1.00)	0.12 (0.65)	0.0262 (0.274)	0.233 (0.886)	0.308 (0.943)	0.273 (0.908)	0.13 (0.685)	0.105 (0.609)	0.0815 (0.526)	0.261 (0.906)	0.381 (1.00)	0.33 (0.972)
CPEB4	7 (1%)	792					0.833 (1.00)	0.532 (1.00)	0.36 (0.998)	0.772 (1.00)	0.798 (1.00)	0.652 (1.00)	0.765 (1.00)	1 (1.00)	0.39 (1.00)	0.304 (0.94)
DNMT3A	11 (1%)	788					0.0821 (0.529)	0.973 (1.00)	0.894 (1.00)	0.184 (0.83)	0.122 (0.657)	0.052 (0.414)	0.302 (0.94)	0.0314 (0.306)	0.739 (1.00)	0.774 (1.00)
TMEM184A	3 (0%)	796					1 (1.00)	0.278 (0.917)	0.476 (1.00)	0.784 (1.00)	0.293 (0.935)	0.786 (1.00)	0.877 (1.00)	0.231 (0.886)	0.629 (1.00)	0.447 (1.00)
G6PC	7 (1%)	792					0.473 (1.00)	0.483 (1.00)	0.342 (0.984)	0.801 (1.00)	1 (1.00)	1 (1.00)	0.407 (1.00)	0.147 (0.719)	0.312 (0.943)	0.735 (1.00)
CYP11A1	7 (1%)	792	0.299 (0.94)	0.891 (1.00)	0.874 (1.00)	0.312 (0.943)	0.473 (1.00)	0.752 (1.00)	0.499 (1.00)	0.45 (1.00)	0.0731 (0.488)	0.389 (1.00)	0.911 (1.00)	0.684 (1.00)	0.579 (1.00)	0.858 (1.00)
KRT15	8 (1%)	791					0.735 (1.00)	0.555 (1.00)	1 (1.00)	0.836 (1.00)	0.514 (1.00)	1 (1.00)	0.517 (1.00)	0.867 (1.00)	0.947 (1.00)	0.864 (1.00)
CMA1	3 (0%)	796					0.663 (1.00)	0.45 (1.00)	1 (1.00)	1 (1.00)
MAP3K12	6 (1%)	793					1 (1.00)	0.447 (1.00)	0.531 (1.00)	1 (1.00)	0.448 (1.00)	0.339 (0.983)	0.486 (1.00)	0.528 (1.00)	0.15 (0.728)	0.185 (0.83)
TREML2	7 (1%)	792	0.136 (0.7)	1 (1.00)	0.645 (1.00)	0.812 (1.00)	0.812 (1.00)	0.759 (1.00)	0.812 (1.00)	1 (1.00)	0.391 (1.00)	0.671 (1.00)	0.52 (1.00)	0.795 (1.00)	0.491 (1.00)	0.677 (1.00)
ESR2	6 (1%)	793	1 (1.00)	0.701 (1.00)	0.778 (1.00)	0.438 (1.00)	0.6 (1.00)	0.756 (1.00)	0.468 (1.00)	0.747 (1.00)	0.559 (1.00)	0.696 (1.00)	0.155 (0.738)	0.428 (1.00)	1 (1.00)	0.225 (0.885)
MACC1	8 (1%)	791	0.545 (1.00)	0.116 (0.636)	0.067 (0.475)	0.258 (0.906)	0.114 (0.636)	0.109 (0.626)	0.064 (0.463)	0.188 (0.83)	0.253 (0.902)	0.0576 (0.441)	0.194 (0.83)	0.196 (0.83)	1 (1.00)	0.714 (1.00)
QKI	6 (1%)	793	0.143 (0.709)	0.0597 (0.448)	0.765 (1.00)	1 (1.00)	0.152 (0.732)	0.356 (0.996)	0.914 (1.00)	0.57 (1.00)	0.782 (1.00)	0.273 (0.908)
KRAS	4 (1%)	795					1 (1.00)	1 (1.00)	1 (1.00)	0.364 (1.00)	1 (1.00)	0.784 (1.00)
TYRP1	6 (1%)	793					0.811 (1.00)	0.868 (1.00)	1 (1.00)	0.366 (1.00)	0.391 (1.00)	0.39 (1.00)	0.403 (1.00)	0.339 (0.983)	0.909 (1.00)	0.47 (1.00)
EMG1	5 (1%)	794					0.77 (1.00)	0.344 (0.987)	0.307 (0.943)	0.544 (1.00)	0.0594 (0.448)	0.153 (0.733)	0.426 (1.00)	0.287 (0.93)	0.189 (0.83)	0.266 (0.908)
HEATR3	4 (1%)	795					0.191 (0.83)	0.232 (0.886)	0.623 (1.00)	0.627 (1.00)	0.78 (1.00)	1 (1.00)
SLC35A2	3 (0%)	796					1 (1.00)				1 (1.00)	1 (1.00)
MYH8	21 (3%)	778	0.717 (1.00)	0.731 (1.00)	0.259 (0.906)	0.0877 (0.547)	0.613 (1.00)	0.0998 (0.596)	0.428 (1.00)	0.229 (0.886)	0.102 (0.602)	0.452 (1.00)	0.853 (1.00)	0.252 (0.902)	0.644 (1.00)	0.488 (1.00)
PAK1	3 (0%)	796					0.665 (1.00)	0.448 (1.00)	0.305 (0.941)	0.626 (1.00)
KRT13	6 (1%)	793	0.546 (1.00)	0.117 (0.637)	1 (1.00)	0.0716 (0.484)	0.419 (1.00)	0.483 (1.00)			0.21 (0.851)	0.824 (1.00)	0.285 (0.93)	0.0519 (0.414)	0.377 (1.00)	0.649 (1.00)
MYO5A	5 (1%)	794					0.148 (0.719)	0.0299 (0.302)	0.47 (1.00)	0.186 (0.83)	0.21 (0.851)	0.822 (1.00)	0.764 (1.00)	0.336 (0.983)	0.416 (1.00)	0.385 (1.00)
MORN5	3 (0%)	796					0.662 (1.00)		0.477 (1.00)	0.48 (1.00)
KRT3	4 (1%)	795					0.749 (1.00)	1 (1.00)	0.305 (0.941)	0.629 (1.00)	0.272 (0.908)	0.695 (1.00)	0.336 (0.983)	0.195 (0.83)	0.11 (0.629)	0.425 (1.00)
LGALS13	4 (1%)	795					0.39 (1.00)	0.0464 (0.4)			1 (1.00)	0.788 (1.00)	0.0491 (0.413)	0.315 (0.945)	0.286 (0.93)	0.169 (0.786)
CD44	6 (1%)	793	0.785 (1.00)	0.266 (0.908)	0.337 (0.983)	0.791 (1.00)	0.421 (1.00)	1 (1.00)	0.0532 (0.418)	0.682 (1.00)	0.293 (0.935)	0.634 (1.00)	0.598 (1.00)	0.233 (0.886)	0.561 (1.00)	0.906 (1.00)
CD1D	4 (1%)	795	0.875 (1.00)	1 (1.00)	0.586 (1.00)	0.122 (0.655)	0.0686 (0.479)	0.11 (0.628)	0.625 (1.00)	0.785 (1.00)
CNOT1	8 (1%)	791					0.734 (1.00)	0.954 (1.00)	0.525 (1.00)	1 (1.00)	0.904 (1.00)	0.0471 (0.402)	0.771 (1.00)	0.694 (1.00)	0.389 (1.00)	0.411 (1.00)
NAP1L2	6 (1%)	793					1 (1.00)	0.582 (1.00)	1 (1.00)	0.249 (0.9)	0.743 (1.00)	0.87 (1.00)	1 (1.00)	0.833 (1.00)	0.621 (1.00)	0.859 (1.00)
OR52M1	8 (1%)	791	0.649 (1.00)	0.601 (1.00)	0.115 (0.636)	0.0593 (0.448)	0.14 (0.707)	0.546 (1.00)	0.505 (1.00)	0.772 (1.00)	0.239 (0.888)	0.27 (0.908)	0.767 (1.00)	1 (1.00)	0.673 (1.00)	0.897 (1.00)
OAS2	4 (1%)	795	1 (1.00)	0.699 (1.00)	0.686 (1.00)	0.791 (1.00)	0.502 (1.00)				0.399 (1.00)	0.104 (0.608)
INF2	4 (1%)	795					1 (1.00)	1 (1.00)	0.702 (1.00)	1 (1.00)	0.512 (1.00)	1 (1.00)	1 (1.00)	0.0522 (0.414)	1 (1.00)	0.646 (1.00)
EPS8L1	4 (1%)	795					0.502 (1.00)	0.451 (1.00)	0.166 (0.779)	0.0622 (0.456)	0.512 (1.00)	1 (1.00)
PRG4	10 (1%)	789					0.391 (1.00)	1 (1.00)	0.342 (0.984)	0.434 (1.00)	0.589 (1.00)	0.196 (0.83)	0.415 (1.00)	0.904 (1.00)	0.962 (1.00)	0.675 (1.00)
RFX4	6 (1%)	793					0.527 (1.00)	0.206 (0.845)	0.467 (1.00)	0.837 (1.00)	0.84 (1.00)	0.312 (0.943)	0.591 (1.00)	0.682 (1.00)	0.231 (0.886)	0.76 (1.00)
LUM	7 (1%)	792	0.546 (1.00)	0.116 (0.636)	0.166 (0.779)	0.713 (1.00)	0.0394 (0.356)	0.355 (0.996)	1 (1.00)	1 (1.00)	0.512 (1.00)	1 (1.00)
KCNJ15	4 (1%)	795					0.746 (1.00)	0.866 (1.00)			0.687 (1.00)	1 (1.00)	0.237 (0.886)	0.101 (0.6)	0.0639 (0.463)	0.705 (1.00)
GFRA4	3 (0%)	796					0.662 (1.00)	0.451 (1.00)
DLX6	5 (1%)	794					0.448 (1.00)	0.904 (1.00)	0.634 (1.00)	1 (1.00)	0.465 (1.00)	1 (1.00)	0.44 (1.00)	0.0766 (0.502)	0.0259 (0.272)	0.449 (1.00)
ROBO3	5 (1%)	794					0.198 (0.832)	0.481 (1.00)	0.191 (0.83)	0.46 (1.00)	0.236 (0.886)	0.341 (0.984)	1 (1.00)	0.286 (0.93)	0.93 (1.00)	0.963 (1.00)
SGOL2	9 (1%)	790	0.618 (1.00)	0.785 (1.00)	0.392 (1.00)	0.604 (1.00)	1 (1.00)	0.896 (1.00)	0.0538 (0.421)	0.457 (1.00)	0.547 (1.00)	0.404 (1.00)	0.869 (1.00)	0.844 (1.00)	0.692 (1.00)	0.779 (1.00)
HTT	5 (1%)	794					0.77 (1.00)	0.0449 (0.394)	0.875 (1.00)	0.852 (1.00)	0.201 (0.838)	0.341 (0.984)	0.26 (0.906)	0.0232 (0.252)	0.467 (1.00)	0.525 (1.00)
SON	9 (1%)	790					0.877 (1.00)	0.836 (1.00)	0.381 (1.00)	0.393 (1.00)	0.491 (1.00)	0.839 (1.00)	0.827 (1.00)	0.519 (1.00)	0.236 (0.886)	0.0302 (0.302)
PLXNA3	10 (1%)	789					0.215 (0.864)	0.537 (1.00)	0.0309 (0.304)	0.521 (1.00)	0.407 (1.00)	0.609 (1.00)	0.355 (0.996)	0.226 (0.885)	0.548 (1.00)	0.272 (0.908)
AMPD1	7 (1%)	792	0.876 (1.00)	0.267 (0.908)	0.521 (1.00)	0.196 (0.83)	0.197 (0.832)	0.11 (0.628)	0.411 (1.00)	0.626 (1.00)	0.456 (1.00)	0.89 (1.00)	0.4 (1.00)	0.339 (0.983)	0.288 (0.93)	0.945 (1.00)
TNFSF9	5 (1%)	794			0.525 (1.00)	0.312 (0.943)	0.6 (1.00)	0.368 (1.00)	0.326 (0.968)	0.454 (1.00)
IL4R	10 (1%)	789	0.847 (1.00)	0.39 (1.00)	0.744 (1.00)	0.803 (1.00)	0.0308 (0.304)	0.703 (1.00)	0.4 (1.00)	0.643 (1.00)	0.142 (0.707)	0.0938 (0.571)
KLKB1	7 (1%)	792					1 (1.00)	0.81 (1.00)	0.247 (0.897)	1 (1.00)	1 (1.00)	0.595 (1.00)	0.928 (1.00)	1 (1.00)	0.291 (0.933)	0.825 (1.00)
CHGB	8 (1%)	791	0.783 (1.00)	0.617 (1.00)	1 (1.00)	0.447 (1.00)	0.361 (0.998)	0.587 (1.00)	0.913 (1.00)	0.303 (0.94)	0.881 (1.00)	0.389 (1.00)	0.765 (1.00)	0.342 (0.984)	0.909 (1.00)	0.856 (1.00)
MYO1B	11 (1%)	788	0.524 (1.00)	0.732 (1.00)	0.292 (0.935)	0.521 (1.00)	0.0514 (0.414)	0.588 (1.00)	0.458 (1.00)	0.355 (0.996)	0.072 (0.484)	0.204 (0.843)	0.488 (1.00)	0.682 (1.00)	0.259 (0.906)	0.57 (1.00)
SMOC1	4 (1%)	795					0.751 (1.00)	0.387 (1.00)			0.84 (1.00)	0.695 (1.00)	0.677 (1.00)	1 (1.00)	0.374 (1.00)	0.648 (1.00)
ACSM1	7 (1%)	792					0.246 (0.897)	0.208 (0.849)	0.765 (1.00)	0.138 (0.703)	0.862 (1.00)	0.193 (0.83)	0.262 (0.906)	0.115 (0.636)	0.234 (0.886)	0.522 (1.00)
CIB1	5 (1%)	794					0.347 (0.989)	0.931 (1.00)	0.766 (1.00)	0.0509 (0.414)	0.688 (1.00)	0.312 (0.943)	0.215 (0.864)	0.0436 (0.388)	0.574 (1.00)	0.259 (0.906)
CDA	3 (0%)	796
TTC30B	7 (1%)	792					0.836 (1.00)	0.646 (1.00)	0.874 (1.00)	0.189 (0.83)	0.573 (1.00)	0.345 (0.988)	0.0767 (0.502)	0.585 (1.00)	0.852 (1.00)	0.446 (1.00)
AGXT2L1	4 (1%)	795					0.5 (1.00)	0.229 (0.886)			0.211 (0.851)	0.822 (1.00)	1 (1.00)	0.794 (1.00)	0.56 (1.00)	1 (1.00)
PRKCD	3 (0%)	796	0.0799 (0.517)	0.0842 (0.537)	0.235 (0.886)	1 (1.00)	0.0503 (0.414)
SYBU	3 (0%)	796					0.271 (0.908)	0.767 (1.00)	0.873 (1.00)	1 (1.00)
SLC2A3	5 (1%)	794					0.249 (0.9)	0.23 (0.886)	0.361 (0.998)	0.685 (1.00)	0.21 (0.851)	0.824 (1.00)	0.0713 (0.484)	0.0513 (0.414)	0.892 (1.00)	0.242 (0.89)
EGR1	5 (1%)	794	0.785 (1.00)	0.785 (1.00)	0.193 (0.83)	0.195 (0.83)	0.0472 (0.402)		0.168 (0.784)	0.0617 (0.456)	0.211 (0.851)	0.824 (1.00)
PRB3	3 (0%)	796					0.269 (0.908)	0.596 (1.00)	0.249 (0.9)	1 (1.00)	0.512 (1.00)	1 (1.00)
FLNB	10 (1%)	789	0.62 (1.00)	0.348 (0.992)	0.151 (0.729)	0.603 (1.00)	0.0484 (0.41)	0.954 (1.00)	0.873 (1.00)	0.71 (1.00)	0.916 (1.00)	0.406 (1.00)	0.468 (1.00)	0.784 (1.00)	0.461 (1.00)	0.971 (1.00)
SLFN11	7 (1%)	792					0.581 (1.00)	0.648 (1.00)	0.529 (1.00)	0.899 (1.00)	1 (1.00)	0.076 (0.5)	0.37 (1.00)	0.12 (0.65)	0.526 (1.00)	0.271 (0.908)
MAX	6 (1%)	793					1 (1.00)	0.147 (0.719)	0.561 (1.00)	1 (1.00)	0.744 (1.00)	0.237 (0.886)	0.277 (0.916)	0.832 (1.00)	0.231 (0.886)	0.46 (1.00)
ZNF148	5 (1%)	794					1 (1.00)	0.113 (0.636)	0.431 (1.00)	0.139 (0.703)	1 (1.00)	0.739 (1.00)	0.536 (1.00)	0.261 (0.906)	0.844 (1.00)	0.0246 (0.26)
PAN3	7 (1%)	792	0.719 (1.00)	0.303 (0.94)	0.253 (0.902)	0.645 (1.00)	0.247 (0.897)		0.302 (0.94)	0.366 (1.00)	0.511 (1.00)	0.489 (1.00)
PPL	9 (1%)	790	0.251 (0.902)	0.702 (1.00)	0.69 (1.00)	0.791 (1.00)	1 (1.00)	0.777 (1.00)	0.237 (0.886)	0.163 (0.769)	0.3 (0.94)	0.634 (1.00)	0.137 (0.7)	0.758 (1.00)	0.734 (1.00)	0.126 (0.669)
GLYAT	5 (1%)	794					1 (1.00)	0.871 (1.00)	0.431 (1.00)	0.683 (1.00)	0.329 (0.971)	0.403 (1.00)	0.196 (0.83)	0.261 (0.906)	1 (1.00)	0.651 (1.00)

'IDH1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.00019 (Fisher's exact test), Q value = 0.0054

Table S1. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
IDH1 MUTATED	1	3	0	9
IDH1 WILD-TYPE	77	38	64	48

Figure S1. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'IDH1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S2. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
IDH1 MUTATED	0	13	0	0
IDH1 WILD-TYPE	63	37	48	79

Figure S2. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'IDH1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 5e-05 (Fisher's exact test), Q value = 0.0017

Table S3. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
IDH1 MUTATED	0	13	1	0
IDH1 WILD-TYPE	70	85	43	63

Figure S3. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

'IDH1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.00288 (Fisher's exact test), Q value = 0.062

Table S4. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
IDH1 MUTATED	13	0	1
IDH1 WILD-TYPE	125	61	75

Figure S4. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

'IDH1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S5. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
IDH1 MUTATED	8	381	23
IDH1 WILD-TYPE	284	51	39

Figure S5. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'IDH1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S6. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
IDH1 MUTATED	0	219	39	148
IDH1 WILD-TYPE	153	4	49	13

Figure S6. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'IDH1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.00389 (Fisher's exact test), Q value = 0.078

Table S7. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
IDH1 MUTATED	111	102	66	65
IDH1 WILD-TYPE	74	53	72	30

Figure S7. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'IDH1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.12 (Fisher's exact test), Q value = 0.65

Table S8. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
IDH1 MUTATED	115	130	99
IDH1 WILD-TYPE	90	90	49

'IDH1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S9. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
IDH1 MUTATED	37	151	221
IDH1 WILD-TYPE	201	40	7

Figure S8. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'IDH1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S10. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
IDH1 MUTATED	1	182	226
IDH1 WILD-TYPE	195	9	44

Figure S9. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'IDH1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00011 (Fisher's exact test), Q value = 0.0034

Table S11. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
IDH1 MUTATED	102	73	77	145
IDH1 WILD-TYPE	38	34	6	37

Figure S10. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'IDH1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S12. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
IDH1 MUTATED	208	154	35
IDH1 WILD-TYPE	15	32	68

Figure S11. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'IDH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S13. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
IDH1 MUTATED	96	76	101	121
IDH1 WILD-TYPE	31	43	5	35

Figure S12. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'IDH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S14. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
IDH1 MUTATED	93	69	90	54	0	88
IDH1 WILD-TYPE	6	8	30	3	63	4

Figure S13. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.00071 (Fisher's exact test), Q value = 0.018

Table S15. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
TP53 MUTATED	17	18	10	24
TP53 WILD-TYPE	61	23	54	33

Figure S14. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'TP53 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 2e-05 (Fisher's exact test), Q value = 0.00076

Table S16. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
TP53 MUTATED	16	30	7	16
TP53 WILD-TYPE	47	20	41	63

Figure S15. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.00108 (Fisher's exact test), Q value = 0.025

Table S17. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
TP53 MUTATED	10	41	10	19
TP53 WILD-TYPE	60	57	34	44

Figure S16. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

'TP53 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.205 (Fisher's exact test), Q value = 0.84

Table S18. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TP53 MUTATED	47	15	18
TP53 WILD-TYPE	91	46	58

'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S19. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TP53 MUTATED	67	228	35
TP53 WILD-TYPE	225	204	27

Figure S17. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S20. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TP53 MUTATED	33	212	24	9
TP53 WILD-TYPE	120	11	64	152

Figure S18. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'TP53 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 0.64

Table S21. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TP53 MUTATED	86	58	54	48
TP53 WILD-TYPE	99	97	84	47

'TP53 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.00942 (Fisher's exact test), Q value = 0.14

Table S22. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TP53 MUTATED	101	96	49
TP53 WILD-TYPE	104	124	99

Figure S19. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S23. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
TP53 MUTATED	81	69	146
TP53 WILD-TYPE	157	122	82

Figure S20. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S24. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
TP53 MUTATED	44	177	75
TP53 WILD-TYPE	152	14	195

Figure S21. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S25. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
TP53 MUTATED	84	71	17	75
TP53 WILD-TYPE	56	36	66	107

Figure S22. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 3e-05 (Fisher's exact test), Q value = 0.0011

Table S26. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
TP53 MUTATED	134	73	40
TP53 WILD-TYPE	89	113	63

Figure S23. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S27. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
TP53 MUTATED	88	66	24	66
TP53 WILD-TYPE	39	53	82	90

Figure S24. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S28. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
TP53 MUTATED	88	47	42	4	8	55
TP53 WILD-TYPE	11	30	78	53	55	37

Figure S25. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ATRX MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.00355 (Fisher's exact test), Q value = 0.073

Table S29. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
ATRX MUTATED	2	4	0	7
ATRX WILD-TYPE	76	37	64	50

Figure S26. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'ATRX MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S30. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
ATRX MUTATED	0	11	0	2
ATRX WILD-TYPE	63	39	48	77

Figure S27. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'ATRX MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.0158 (Fisher's exact test), Q value = 0.2

Table S31. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
ATRX MUTATED	3	11	2	0
ATRX WILD-TYPE	67	87	42	63

Figure S28. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

'ATRX MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.0185 (Fisher's exact test), Q value = 0.21

Table S32. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
ATRX MUTATED	13	0	3
ATRX WILD-TYPE	125	61	73

Figure S29. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

'ATRX MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S33. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ATRX MUTATED	11	184	18
ATRX WILD-TYPE	281	248	44

Figure S30. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'ATRX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S34. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ATRX MUTATED	6	171	23	5
ATRX WILD-TYPE	147	52	65	156

Figure S31. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'ATRX MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.00642 (Fisher's exact test), Q value = 0.11

Table S35. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ATRX MUTATED	56	48	31	42
ATRX WILD-TYPE	129	107	107	53

Figure S32. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'ATRX MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.738 (Fisher's exact test), Q value = 1

Table S36. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ATRX MUTATED	62	72	43
ATRX WILD-TYPE	143	148	105

'ATRX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S37. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
ATRX MUTATED	34	57	115
ATRX WILD-TYPE	204	134	113

Figure S33. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'ATRX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S38. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
ATRX MUTATED	5	141	60
ATRX WILD-TYPE	191	50	210

Figure S34. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'ATRX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S39. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
ATRX MUTATED	63	61	10	60
ATRX WILD-TYPE	77	46	73	122

Figure S35. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'ATRX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 2e-05 (Fisher's exact test), Q value = 0.00076

Table S40. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
ATRX MUTATED	109	60	25
ATRX WILD-TYPE	114	126	78

Figure S36. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'ATRX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S41. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
ATRX MUTATED	70	53	16	52
ATRX WILD-TYPE	57	66	90	104

Figure S37. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'ATRX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S42. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
ATRX MUTATED	69	41	34	2	3	42
ATRX WILD-TYPE	30	36	86	55	60	50

Figure S38. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CIC MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S43. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
CIC MUTATED	1	108	0
CIC WILD-TYPE	291	324	62

Figure S39. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'CIC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S44. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
CIC MUTATED	1	0	5	102
CIC WILD-TYPE	152	223	83	59

Figure S40. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'CIC MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.00566 (Fisher's exact test), Q value = 0.1

Table S45. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
CIC MUTATED	36	29	25	5
CIC WILD-TYPE	149	126	113	90

Figure S41. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'CIC MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.264 (Fisher's exact test), Q value = 0.91

Table S46. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
CIC MUTATED	30	34	31
CIC WILD-TYPE	175	186	117

'CIC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S47. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
CIC MUTATED	2	52	55
CIC WILD-TYPE	236	139	173

Figure S42. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'CIC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S48. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
CIC MUTATED	0	5	104
CIC WILD-TYPE	196	186	166

Figure S43. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'CIC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S49. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
CIC MUTATED	17	3	46	42
CIC WILD-TYPE	123	104	37	140

Figure S44. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'CIC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S50. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
CIC MUTATED	55	51	2
CIC WILD-TYPE	168	135	101

Figure S45. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'CIC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S51. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
CIC MUTATED	7	8	60	33
CIC WILD-TYPE	120	111	46	123

Figure S46. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'CIC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S52. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
CIC MUTATED	2	16	25	43	0	22
CIC WILD-TYPE	97	61	95	14	63	70

Figure S47. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'NF1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.103 (Fisher's exact test), Q value = 0.61

Table S53. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
NF1 MUTATED	12	3	4	2
NF1 WILD-TYPE	66	38	60	55

'NF1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 4e-04 (Fisher's exact test), Q value = 0.011

Table S54. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
NF1 MUTATED	14	1	1	5
NF1 WILD-TYPE	49	49	47	74

Figure S48. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'NF1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.0335 (Fisher's exact test), Q value = 0.32

Table S55. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
NF1 MUTATED	12	4	4	8
NF1 WILD-TYPE	58	94	40	55

Figure S49. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

'NF1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.932 (Fisher's exact test), Q value = 1

Table S56. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
NF1 MUTATED	14	7	7
NF1 WILD-TYPE	124	54	69

'NF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00015 (Fisher's exact test), Q value = 0.0044

Table S57. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
NF1 MUTATED	30	20	12
NF1 WILD-TYPE	262	412	50

Figure S50. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'NF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S58. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
NF1 MUTATED	21	2	16	7
NF1 WILD-TYPE	132	221	72	154

Figure S51. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'NF1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S59. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
NF1 MUTATED	12	11	13	5
NF1 WILD-TYPE	173	144	125	90

'NF1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 4e-05 (Fisher's exact test), Q value = 0.0014

Table S60. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
NF1 MUTATED	27	4	10
NF1 WILD-TYPE	178	216	138

Figure S52. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

'NF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00029 (Fisher's exact test), Q value = 0.008

Table S61. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
NF1 MUTATED	28	10	6
NF1 WILD-TYPE	210	181	222

Figure S53. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'NF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00162 (Fisher's exact test), Q value = 0.037

Table S62. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
NF1 MUTATED	24	7	13
NF1 WILD-TYPE	172	184	257

Figure S54. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'NF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.359 (Fisher's exact test), Q value = 1

Table S63. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
NF1 MUTATED	8	11	5	9
NF1 WILD-TYPE	132	96	78	173

'NF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00013 (Fisher's exact test), Q value = 0.0039

Table S64. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
NF1 MUTATED	10	6	17
NF1 WILD-TYPE	213	180	86

Figure S55. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.356 (Fisher's exact test), Q value = 1

Table S65. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
NF1 MUTATED	11	10	5	7
NF1 WILD-TYPE	116	109	101	149

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 2e-05 (Fisher's exact test), Q value = 0.00076

Table S66. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
NF1 MUTATED	1	4	5	2	16	5
NF1 WILD-TYPE	98	73	115	55	47	87

Figure S56. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PIK3R1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.414 (Fisher's exact test), Q value = 1

Table S67. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
PIK3R1 MUTATED	8	1	7	6
PIK3R1 WILD-TYPE	70	40	57	51

'PIK3R1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.193 (Fisher's exact test), Q value = 0.83

Table S68. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PIK3R1 MUTATED	7	6	6	3
PIK3R1 WILD-TYPE	56	44	42	76

'PIK3R1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.0616 (Fisher's exact test), Q value = 0.46

Table S69. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
PIK3R1 MUTATED	13	13	3	3
PIK3R1 WILD-TYPE	57	85	41	60

'PIK3R1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.529 (Fisher's exact test), Q value = 1

Table S70. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PIK3R1 MUTATED	16	5	11
PIK3R1 WILD-TYPE	122	56	65

'PIK3R1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0917 (Fisher's exact test), Q value = 0.57

Table S71. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PIK3R1 MUTATED	27	22	4
PIK3R1 WILD-TYPE	265	410	58

'PIK3R1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 9e-05 (Fisher's exact test), Q value = 0.0029

Table S72. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
PIK3R1 MUTATED	20	5	2	13
PIK3R1 WILD-TYPE	133	218	86	148

Figure S57. Get High-res Image Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'PIK3R1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S73. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PIK3R1 MUTATED	15	11	8	8
PIK3R1 WILD-TYPE	170	144	130	87

'PIK3R1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.919 (Fisher's exact test), Q value = 1

Table S74. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PIK3R1 MUTATED	16	15	11
PIK3R1 WILD-TYPE	189	205	137

'PIK3R1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 0.83

Table S75. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
PIK3R1 MUTATED	17	6	11
PIK3R1 WILD-TYPE	221	185	217

'PIK3R1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.927 (Fisher's exact test), Q value = 1

Table S76. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
PIK3R1 MUTATED	11	10	13
PIK3R1 WILD-TYPE	185	181	257

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0901 (Fisher's exact test), Q value = 0.56

Table S77. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
PIK3R1 MUTATED	6	3	8	5
PIK3R1 WILD-TYPE	134	104	75	177

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.582 (Fisher's exact test), Q value = 1

Table S78. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
PIK3R1 MUTATED	12	7	3
PIK3R1 WILD-TYPE	211	179	100

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.905 (Fisher's exact test), Q value = 1

Table S79. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
PIK3R1 MUTATED	5	5	6	6
PIK3R1 WILD-TYPE	122	114	100	150

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.7 (Fisher's exact test), Q value = 1

Table S80. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
PIK3R1 MUTATED	3	3	5	5	2	4
PIK3R1 WILD-TYPE	96	74	115	52	61	88

'NOTCH1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S81. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
NOTCH1 MUTATED	1	41	0
NOTCH1 WILD-TYPE	291	391	62

Figure S58. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'NOTCH1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S82. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
NOTCH1 MUTATED	1	9	0	32
NOTCH1 WILD-TYPE	152	214	88	129

Figure S59. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'NOTCH1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.733 (Fisher's exact test), Q value = 1

Table S83. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
NOTCH1 MUTATED	13	9	12	5
NOTCH1 WILD-TYPE	172	146	126	90

'NOTCH1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S84. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
NOTCH1 MUTATED	14	15	10
NOTCH1 WILD-TYPE	191	205	138

'NOTCH1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S85. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
NOTCH1 MUTATED	3	24	15
NOTCH1 WILD-TYPE	235	167	213

Figure S60. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'NOTCH1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S86. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
NOTCH1 MUTATED	0	6	36
NOTCH1 WILD-TYPE	196	185	234

Figure S61. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'NOTCH1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00016 (Fisher's exact test), Q value = 0.0046

Table S87. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
NOTCH1 MUTATED	4	3	14	20
NOTCH1 WILD-TYPE	136	104	69	162

Figure S62. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'NOTCH1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00496 (Fisher's exact test), Q value = 0.093

Table S88. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
NOTCH1 MUTATED	16	23	2
NOTCH1 WILD-TYPE	207	163	101

Figure S63. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'NOTCH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S89. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
NOTCH1 MUTATED	2	3	16	20
NOTCH1 WILD-TYPE	125	116	90	136

Figure S64. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'NOTCH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0046 (Fisher's exact test), Q value = 0.089

Table S90. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
NOTCH1 MUTATED	3	7	15	7	0	9
NOTCH1 WILD-TYPE	96	70	105	50	63	83

Figure S65. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'IDH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00065 (Fisher's exact test), Q value = 0.017

Table S91. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
IDH2 MUTATED	1	19	0
IDH2 WILD-TYPE	291	413	62

Figure S66. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'IDH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00011 (Fisher's exact test), Q value = 0.0034

Table S92. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
IDH2 MUTATED	0	3	4	13
IDH2 WILD-TYPE	153	220	84	148

Figure S67. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'IDH2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.83

Table S93. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
IDH2 MUTATED	6	7	4	0
IDH2 WILD-TYPE	179	148	134	95

'IDH2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.135 (Fisher's exact test), Q value = 0.7

Table S94. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
IDH2 MUTATED	7	3	7
IDH2 WILD-TYPE	198	217	141

'IDH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 2e-05 (Fisher's exact test), Q value = 0.00076

Table S95. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
IDH2 MUTATED	0	14	6
IDH2 WILD-TYPE	238	177	222

Figure S68. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'IDH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 2e-05 (Fisher's exact test), Q value = 0.00076

Table S96. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
IDH2 MUTATED	0	1	19
IDH2 WILD-TYPE	196	190	251

Figure S69. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'IDH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00869 (Fisher's exact test), Q value = 0.13

Table S97. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
IDH2 MUTATED	3	0	5	12
IDH2 WILD-TYPE	137	107	78	170

Figure S70. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'IDH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00075 (Fisher's exact test), Q value = 0.019

Table S98. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
IDH2 MUTATED	5	15	0
IDH2 WILD-TYPE	218	171	103

Figure S71. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'IDH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0392 (Fisher's exact test), Q value = 0.36

Table S99. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
IDH2 MUTATED	1	3	5	11
IDH2 WILD-TYPE	126	116	101	145

Figure S72. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'IDH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0665 (Fisher's exact test), Q value = 0.47

Table S100. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
IDH2 MUTATED	2	3	10	3	0	2
IDH2 WILD-TYPE	97	74	110	54	63	90

'TCF12 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S101. Gene #9: 'TCF12 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
TCF12 MUTATED	1	0	1	1
TCF12 WILD-TYPE	77	41	63	56

'TCF12 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S102. Gene #9: 'TCF12 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
TCF12 MUTATED	1	1	1	0
TCF12 WILD-TYPE	62	49	47	79

'TCF12 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S103. Gene #9: 'TCF12 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
TCF12 MUTATED	2	2	0	0
TCF12 WILD-TYPE	68	96	44	63

'TCF12 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.259 (Fisher's exact test), Q value = 0.91

Table S104. Gene #9: 'TCF12 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TCF12 MUTATED	2	2	0
TCF12 WILD-TYPE	136	59	76

'TCF12 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.134 (Fisher's exact test), Q value = 0.69

Table S105. Gene #9: 'TCF12 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TCF12 MUTATED	3	14	1
TCF12 WILD-TYPE	289	418	61

'TCF12 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.423 (Fisher's exact test), Q value = 1

Table S106. Gene #9: 'TCF12 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TCF12 MUTATED	3	4	3	7
TCF12 WILD-TYPE	150	219	85	154

'TCF12 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.558 (Fisher's exact test), Q value = 1

Table S107. Gene #9: 'TCF12 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TCF12 MUTATED	6	2	5	3
TCF12 WILD-TYPE	179	153	133	92

'TCF12 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.383 (Fisher's exact test), Q value = 1

Table S108. Gene #9: 'TCF12 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TCF12 MUTATED	8	6	2
TCF12 WILD-TYPE	197	214	146

'TCF12 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0835 (Fisher's exact test), Q value = 0.53

Table S109. Gene #9: 'TCF12 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
TCF12 MUTATED	2	5	9
TCF12 WILD-TYPE	236	186	219

'TCF12 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.294 (Fisher's exact test), Q value = 0.94

Table S110. Gene #9: 'TCF12 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
TCF12 MUTATED	2	6	8
TCF12 WILD-TYPE	194	185	262

'TCF12 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S111. Gene #9: 'TCF12 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
TCF12 MUTATED	5	2	3	5
TCF12 WILD-TYPE	135	105	80	177

'TCF12 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S112. Gene #9: 'TCF12 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
TCF12 MUTATED	8	6	1
TCF12 WILD-TYPE	215	180	102

'TCF12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0792 (Fisher's exact test), Q value = 0.51

Table S113. Gene #9: 'TCF12 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
TCF12 MUTATED	5	0	5	5
TCF12 WILD-TYPE	122	119	101	151

'TCF12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.36 (Fisher's exact test), Q value = 1

Table S114. Gene #9: 'TCF12 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
TCF12 MUTATED	4	0	5	3	1	2
TCF12 WILD-TYPE	95	77	115	54	62	90

'PIK3CA MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.92 (Fisher's exact test), Q value = 1

Table S115. Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
PIK3CA MUTATED	7	5	7	5
PIK3CA WILD-TYPE	71	36	57	52

'PIK3CA MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.288 (Fisher's exact test), Q value = 0.93

Table S116. Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PIK3CA MUTATED	8	6	6	4
PIK3CA WILD-TYPE	55	44	42	75

'PIK3CA MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.275 (Fisher's exact test), Q value = 0.91

Table S117. Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
PIK3CA MUTATED	9	10	1	6
PIK3CA WILD-TYPE	61	88	43	57

'PIK3CA MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S118. Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PIK3CA MUTATED	12	6	8
PIK3CA WILD-TYPE	126	55	68

'PIK3CA MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S119. Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PIK3CA MUTATED	26	38	5
PIK3CA WILD-TYPE	266	394	57

'PIK3CA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S120. Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
PIK3CA MUTATED	21	4	8	24
PIK3CA WILD-TYPE	132	219	80	137

Figure S73. Get High-res Image Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'PIK3CA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.29 (Fisher's exact test), Q value = 0.93

Table S121. Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PIK3CA MUTATED	12	18	14	6
PIK3CA WILD-TYPE	173	137	124	89

'PIK3CA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S122. Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PIK3CA MUTATED	19	15	16
PIK3CA WILD-TYPE	186	205	132

'PIK3CA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S123. Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
PIK3CA MUTATED	23	15	16
PIK3CA WILD-TYPE	215	176	212

'PIK3CA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0392 (Fisher's exact test), Q value = 0.36

Table S124. Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
PIK3CA MUTATED	18	8	28
PIK3CA WILD-TYPE	178	183	242

Figure S74. Get High-res Image Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0274 (Fisher's exact test), Q value = 0.28

Table S125. Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
PIK3CA MUTATED	6	14	11	13
PIK3CA WILD-TYPE	134	93	72	169

Figure S75. Get High-res Image Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0373 (Fisher's exact test), Q value = 0.34

Table S126. Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
PIK3CA MUTATED	13	16	15
PIK3CA WILD-TYPE	210	170	88

Figure S76. Get High-res Image Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.206 (Fisher's exact test), Q value = 0.84

Table S127. Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
PIK3CA MUTATED	6	10	13	15
PIK3CA WILD-TYPE	121	109	93	141

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S128. Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
PIK3CA MUTATED	0	4	13	13	10	4
PIK3CA WILD-TYPE	99	73	107	44	53	88

Figure S77. Get High-res Image Gene #10: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0845 (Fisher's exact test), Q value = 0.54

Table S129. Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
RB1 MUTATED	11	1	3	3
RB1 WILD-TYPE	67	40	61	54

'RB1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0176 (Fisher's exact test), Q value = 0.21

Table S130. Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
RB1 MUTATED	5	2	0	11
RB1 WILD-TYPE	58	48	48	68

Figure S78. Get High-res Image Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 0.61

Table S131. Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
RB1 MUTATED	10	4	3	7
RB1 WILD-TYPE	60	94	41	56

'RB1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.922 (Fisher's exact test), Q value = 1

Table S132. Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
RB1 MUTATED	12	6	6
RB1 WILD-TYPE	126	55	70

'RB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S133. Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
RB1 MUTATED	25	0	5
RB1 WILD-TYPE	267	432	57

Figure S79. Get High-res Image Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'RB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 3e-05 (Fisher's exact test), Q value = 0.0011

Table S134. Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
RB1 MUTATED	10	0	3	1
RB1 WILD-TYPE	143	223	85	160

Figure S80. Get High-res Image Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'RB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.308 (Fisher's exact test), Q value = 0.94

Table S135. Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
RB1 MUTATED	6	2	6	1
RB1 WILD-TYPE	179	153	132	94

'RB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.179 (Fisher's exact test), Q value = 0.82

Table S136. Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
RB1 MUTATED	9	4	2
RB1 WILD-TYPE	196	216	146

'RB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00011 (Fisher's exact test), Q value = 0.0034

Table S137. Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
RB1 MUTATED	14	1	1
RB1 WILD-TYPE	224	190	227

Figure S81. Get High-res Image Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'RB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 7e-05 (Fisher's exact test), Q value = 0.0024

Table S138. Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
RB1 MUTATED	13	1	2
RB1 WILD-TYPE	183	190	268

Figure S82. Get High-res Image Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S139. Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
RB1 MUTATED	3	1	1	1
RB1 WILD-TYPE	137	106	82	181

'RB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0341 (Fisher's exact test), Q value = 0.32

Table S140. Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
RB1 MUTATED	1	1	4
RB1 WILD-TYPE	222	185	99

Figure S83. Get High-res Image Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S141. Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
RB1 MUTATED	2	2	0	2
RB1 WILD-TYPE	125	117	106	154

'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.094 (Fisher's exact test), Q value = 0.57

Table S142. Gene #11: 'RB1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
RB1 MUTATED	0	0	1	1	3	1
RB1 WILD-TYPE	99	77	119	56	60	91

'FUBP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S143. Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
FUBP1 MUTATED	1	46	0
FUBP1 WILD-TYPE	291	386	62

Figure S84. Get High-res Image Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'FUBP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S144. Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
FUBP1 MUTATED	1	0	2	44
FUBP1 WILD-TYPE	152	223	86	117

Figure S85. Get High-res Image Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'FUBP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.16 (Fisher's exact test), Q value = 0.76

Table S145. Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
FUBP1 MUTATED	14	13	12	2
FUBP1 WILD-TYPE	171	142	126	93

'FUBP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.426 (Fisher's exact test), Q value = 1

Table S146. Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
FUBP1 MUTATED	11	17	13
FUBP1 WILD-TYPE	194	203	135

'FUBP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S147. Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
FUBP1 MUTATED	1	24	22
FUBP1 WILD-TYPE	237	167	206

Figure S86. Get High-res Image Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'FUBP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S148. Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
FUBP1 MUTATED	0	3	44
FUBP1 WILD-TYPE	196	188	226

Figure S87. Get High-res Image Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'FUBP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S149. Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
FUBP1 MUTATED	6	1	19	21
FUBP1 WILD-TYPE	134	106	64	161

Figure S88. Get High-res Image Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'FUBP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00104 (Fisher's exact test), Q value = 0.025

Table S150. Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
FUBP1 MUTATED	24	22	1
FUBP1 WILD-TYPE	199	164	102

Figure S89. Get High-res Image Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'FUBP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 8e-05 (Fisher's exact test), Q value = 0.0027

Table S151. Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
FUBP1 MUTATED	6	4	21	16
FUBP1 WILD-TYPE	121	115	85	140

Figure S90. Get High-res Image Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'FUBP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S152. Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
FUBP1 MUTATED	0	6	15	15	0	11
FUBP1 WILD-TYPE	99	71	105	42	63	81

Figure S91. Get High-res Image Gene #12: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.151 (Fisher's exact test), Q value = 0.73

Table S153. Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
PTEN MUTATED	27	9	16	23
PTEN WILD-TYPE	51	32	48	34

'PTEN MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0753 (Fisher's exact test), Q value = 0.5

Table S154. Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PTEN MUTATED	18	16	9	32
PTEN WILD-TYPE	45	34	39	47

'PTEN MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.0449 (Fisher's exact test), Q value = 0.39

Table S155. Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
PTEN MUTATED	26	21	18	22
PTEN WILD-TYPE	44	77	26	41

Figure S92. Get High-res Image Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

'PTEN MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.647 (Fisher's exact test), Q value = 1

Table S156. Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PTEN MUTATED	45	21	21
PTEN WILD-TYPE	93	40	55

'PTEN MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S157. Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PTEN MUTATED	89	8	12
PTEN WILD-TYPE	203	424	50

Figure S93. Get High-res Image Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'PTEN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S158. Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
PTEN MUTATED	46	3	7	1
PTEN WILD-TYPE	107	220	81	160

Figure S94. Get High-res Image Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'PTEN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.705 (Fisher's exact test), Q value = 1

Table S159. Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PTEN MUTATED	19	13	17	11
PTEN WILD-TYPE	166	142	121	84

'PTEN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.113 (Fisher's exact test), Q value = 0.64

Table S160. Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PTEN MUTATED	29	19	12
PTEN WILD-TYPE	176	201	136

'PTEN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S161. Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
PTEN MUTATED	62	3	4
PTEN WILD-TYPE	176	188	224

Figure S95. Get High-res Image Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'PTEN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S162. Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
PTEN MUTATED	61	4	4
PTEN WILD-TYPE	135	187	266

Figure S96. Get High-res Image Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00411 (Fisher's exact test), Q value = 0.081

Table S163. Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
PTEN MUTATED	12	8	1	3
PTEN WILD-TYPE	128	99	82	179

Figure S97. Get High-res Image Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'PTEN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S164. Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
PTEN MUTATED	6	1	17
PTEN WILD-TYPE	217	185	86

Figure S98. Get High-res Image Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00035 (Fisher's exact test), Q value = 0.0095

Table S165. Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
PTEN MUTATED	8	13	1	2
PTEN WILD-TYPE	119	106	105	154

Figure S99. Get High-res Image Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S166. Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
PTEN MUTATED	3	1	0	1	17	2
PTEN WILD-TYPE	96	76	120	56	46	90

Figure S100. Get High-res Image Gene #13: 'PTEN MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'STK19 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.903 (Fisher's exact test), Q value = 1

Table S167. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
STK19 MUTATED	4	7	0
STK19 WILD-TYPE	288	425	62

'STK19 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.681 (Fisher's exact test), Q value = 1

Table S168. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
STK19 MUTATED	3	4	2	1
STK19 WILD-TYPE	150	219	86	160

'STK19 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.424 (Fisher's exact test), Q value = 1

Table S169. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
STK19 MUTATED	3	2	0	2
STK19 WILD-TYPE	182	153	138	93

'STK19 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.632 (Fisher's exact test), Q value = 1

Table S170. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
STK19 MUTATED	2	2	3
STK19 WILD-TYPE	203	218	145

'STK19 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.382 (Fisher's exact test), Q value = 1

Table S171. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
STK19 MUTATED	4	5	2
STK19 WILD-TYPE	234	186	226

'STK19 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.863 (Fisher's exact test), Q value = 1

Table S172. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
STK19 MUTATED	3	4	4
STK19 WILD-TYPE	193	187	266

'STK19 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.157 (Fisher's exact test), Q value = 0.74

Table S173. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
STK19 MUTATED	1	4	0	5
STK19 WILD-TYPE	139	103	83	177

'STK19 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S174. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
STK19 MUTATED	3	4	3
STK19 WILD-TYPE	220	182	100

'STK19 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00651 (Fisher's exact test), Q value = 0.11

Table S175. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
STK19 MUTATED	0	6	0	4
STK19 WILD-TYPE	127	113	106	152

Figure S101. Get High-res Image Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'STK19 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.723 (Fisher's exact test), Q value = 1

Table S176. Gene #14: 'STK19 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
STK19 MUTATED	1	1	3	0	2	3
STK19 WILD-TYPE	98	76	117	57	61	89

'ZMIZ1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.649 (Fisher's exact test), Q value = 1

Table S177. Gene #15: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
ZMIZ1 MUTATED	2	1	0	1
ZMIZ1 WILD-TYPE	76	40	64	56

'ZMIZ1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.911 (Fisher's exact test), Q value = 1

Table S178. Gene #15: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
ZMIZ1 MUTATED	1	1	0	2
ZMIZ1 WILD-TYPE	62	49	48	77

'ZMIZ1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.538 (Fisher's exact test), Q value = 1

Table S179. Gene #15: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
ZMIZ1 MUTATED	1	3	0	0
ZMIZ1 WILD-TYPE	69	95	44	63

'ZMIZ1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S180. Gene #15: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
ZMIZ1 MUTATED	1	1	2
ZMIZ1 WILD-TYPE	137	60	74

'ZMIZ1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.195 (Fisher's exact test), Q value = 0.83

Table S181. Gene #15: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ZMIZ1 MUTATED	2	10	0
ZMIZ1 WILD-TYPE	290	422	62

'ZMIZ1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.25 (Fisher's exact test), Q value = 0.9

Table S182. Gene #15: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ZMIZ1 MUTATED	2	2	0	5
ZMIZ1 WILD-TYPE	151	221	88	156

'ZMIZ1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 0.63

Table S183. Gene #15: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ZMIZ1 MUTATED	3	5	0	3
ZMIZ1 WILD-TYPE	182	150	138	92

'ZMIZ1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 0.64

Table S184. Gene #15: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ZMIZ1 MUTATED	3	2	6
ZMIZ1 WILD-TYPE	202	218	142

'ZMIZ1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.749 (Fisher's exact test), Q value = 1

Table S185. Gene #15: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
ZMIZ1 MUTATED	3	3	5
ZMIZ1 WILD-TYPE	235	188	223

'ZMIZ1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.346 (Fisher's exact test), Q value = 0.99

Table S186. Gene #15: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
ZMIZ1 MUTATED	1	4	6
ZMIZ1 WILD-TYPE	195	187	264

'ZMIZ1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S187. Gene #15: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
ZMIZ1 MUTATED	1	2	3	3
ZMIZ1 WILD-TYPE	139	105	80	179

'ZMIZ1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S188. Gene #15: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
ZMIZ1 MUTATED	5	2	2
ZMIZ1 WILD-TYPE	218	184	101

'ZMIZ1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0872 (Fisher's exact test), Q value = 0.55

Table S189. Gene #15: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
ZMIZ1 MUTATED	0	1	4	4
ZMIZ1 WILD-TYPE	127	118	102	152

'ZMIZ1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.136 (Fisher's exact test), Q value = 0.7

Table S190. Gene #15: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
ZMIZ1 MUTATED	0	1	1	3	1	3
ZMIZ1 WILD-TYPE	99	76	119	54	62	89

'ARID1A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0138 (Fisher's exact test), Q value = 0.18

Table S191. Gene #16: 'ARID1A MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ARID1A MUTATED	2	17	2
ARID1A WILD-TYPE	290	415	60

Figure S102. Get High-res Image Gene #16: 'ARID1A MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'ARID1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0156 (Fisher's exact test), Q value = 0.19

Table S192. Gene #16: 'ARID1A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ARID1A MUTATED	2	6	1	12
ARID1A WILD-TYPE	151	217	87	149

Figure S103. Get High-res Image Gene #16: 'ARID1A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'ARID1A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.244 (Fisher's exact test), Q value = 0.89

Table S193. Gene #16: 'ARID1A MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ARID1A MUTATED	9	4	2	5
ARID1A WILD-TYPE	176	151	136	90

'ARID1A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S194. Gene #16: 'ARID1A MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ARID1A MUTATED	7	8	5
ARID1A WILD-TYPE	198	212	143

'ARID1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0139 (Fisher's exact test), Q value = 0.18

Table S195. Gene #16: 'ARID1A MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
ARID1A MUTATED	2	7	12
ARID1A WILD-TYPE	236	184	216

Figure S104. Get High-res Image Gene #16: 'ARID1A MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'ARID1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00607 (Fisher's exact test), Q value = 0.11

Table S196. Gene #16: 'ARID1A MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
ARID1A MUTATED	1	5	15
ARID1A WILD-TYPE	195	186	255

Figure S105. Get High-res Image Gene #16: 'ARID1A MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'ARID1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.519 (Fisher's exact test), Q value = 1

Table S197. Gene #16: 'ARID1A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
ARID1A MUTATED	6	2	5	7
ARID1A WILD-TYPE	134	105	78	175

'ARID1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.604 (Fisher's exact test), Q value = 1

Table S198. Gene #16: 'ARID1A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
ARID1A MUTATED	10	8	2
ARID1A WILD-TYPE	213	178	101

'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00486 (Fisher's exact test), Q value = 0.092

Table S199. Gene #16: 'ARID1A MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
ARID1A MUTATED	2	1	10	7
ARID1A WILD-TYPE	125	118	96	149

Figure S106. Get High-res Image Gene #16: 'ARID1A MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0615 (Fisher's exact test), Q value = 0.46

Table S200. Gene #16: 'ARID1A MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
ARID1A MUTATED	2	3	3	7	1	4
ARID1A WILD-TYPE	97	74	117	50	62	88

'NIPBL MUTATION STATUS' versus 'CN_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.83

Table S201. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
NIPBL MUTATED	4	15	1
NIPBL WILD-TYPE	288	417	61

'NIPBL MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 4e-05 (Fisher's exact test), Q value = 0.0014

Table S202. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
NIPBL MUTATED	3	2	0	14
NIPBL WILD-TYPE	150	221	88	147

Figure S107. Get High-res Image Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'NIPBL MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.647 (Fisher's exact test), Q value = 1

Table S203. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
NIPBL MUTATED	6	2	4	3
NIPBL WILD-TYPE	179	153	134	92

'NIPBL MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.57 (Fisher's exact test), Q value = 1

Table S204. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
NIPBL MUTATED	6	7	2
NIPBL WILD-TYPE	199	213	146

'NIPBL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0336 (Fisher's exact test), Q value = 0.32

Table S205. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
NIPBL MUTATED	3	4	12
NIPBL WILD-TYPE	235	187	216

Figure S108. Get High-res Image Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'NIPBL MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0494 (Fisher's exact test), Q value = 0.41

Table S206. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
NIPBL MUTATED	2	4	13
NIPBL WILD-TYPE	194	187	257

Figure S109. Get High-res Image Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'NIPBL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S207. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
NIPBL MUTATED	5	4	5	4
NIPBL WILD-TYPE	135	103	78	178

'NIPBL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.171 (Fisher's exact test), Q value = 0.8

Table S208. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
NIPBL MUTATED	12	4	2
NIPBL WILD-TYPE	211	182	101

'NIPBL MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.031 (Fisher's exact test), Q value = 0.3

Table S209. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
NIPBL MUTATED	2	4	9	3
NIPBL WILD-TYPE	125	115	97	153

Figure S110. Get High-res Image Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'NIPBL MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.035 (Fisher's exact test), Q value = 0.33

Table S210. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
NIPBL MUTATED	3	3	2	7	1	2
NIPBL WILD-TYPE	96	74	118	50	62	90

Figure S111. Get High-res Image Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'GAGE2A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 0.94

Table S211. Gene #18: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
GAGE2A MUTATED	1	6	1
GAGE2A WILD-TYPE	291	426	61

'GAGE2A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S212. Gene #18: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
GAGE2A MUTATED	1	4	0	3
GAGE2A WILD-TYPE	152	219	88	158

'GAGE2A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S213. Gene #18: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
GAGE2A MUTATED	3	3	2	0
GAGE2A WILD-TYPE	182	152	136	95

'GAGE2A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.289 (Fisher's exact test), Q value = 0.93

Table S214. Gene #18: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
GAGE2A MUTATED	4	1	3
GAGE2A WILD-TYPE	201	219	145

'GAGE2A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.827 (Fisher's exact test), Q value = 1

Table S215. Gene #18: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
GAGE2A MUTATED	2	3	3
GAGE2A WILD-TYPE	236	188	225

'GAGE2A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.609 (Fisher's exact test), Q value = 1

Table S216. Gene #18: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
GAGE2A MUTATED	1	3	4
GAGE2A WILD-TYPE	195	188	266

'GAGE2A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.655 (Fisher's exact test), Q value = 1

Table S217. Gene #18: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
GAGE2A MUTATED	1	3	1	3
GAGE2A WILD-TYPE	139	104	82	179

'GAGE2A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.901 (Fisher's exact test), Q value = 1

Table S218. Gene #18: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
GAGE2A MUTATED	3	3	2
GAGE2A WILD-TYPE	220	183	101

'GAGE2A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 0.78

Table S219. Gene #18: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
GAGE2A MUTATED	0	4	1	3
GAGE2A WILD-TYPE	127	115	105	153

'GAGE2A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.685 (Fisher's exact test), Q value = 1

Table S220. Gene #18: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
GAGE2A MUTATED	1	3	2	0	1	1
GAGE2A WILD-TYPE	98	74	118	57	62	91

'NUDT11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.123 (Fisher's exact test), Q value = 0.66

Table S221. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
NUDT11 MUTATED	1	9	1
NUDT11 WILD-TYPE	291	423	61

'NUDT11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.262 (Fisher's exact test), Q value = 0.91

Table S222. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
NUDT11 MUTATED	1	6	0	4
NUDT11 WILD-TYPE	152	217	88	157

'NUDT11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S223. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
NUDT11 MUTATED	5	2	3	1
NUDT11 WILD-TYPE	180	153	135	94

'NUDT11 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.295 (Fisher's exact test), Q value = 0.94

Table S224. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
NUDT11 MUTATED	6	2	3
NUDT11 WILD-TYPE	199	218	145

'NUDT11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.325 (Fisher's exact test), Q value = 0.97

Table S225. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
NUDT11 MUTATED	2	3	6
NUDT11 WILD-TYPE	236	188	222

'NUDT11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0147 (Fisher's exact test), Q value = 0.19

Table S226. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
NUDT11 MUTATED	0	7	4
NUDT11 WILD-TYPE	196	184	266

Figure S112. Get High-res Image Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'NUDT11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.027 (Fisher's exact test), Q value = 0.28

Table S227. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
NUDT11 MUTATED	1	4	4	1
NUDT11 WILD-TYPE	139	103	79	181

Figure S113. Get High-res Image Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'NUDT11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.919 (Fisher's exact test), Q value = 1

Table S228. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
NUDT11 MUTATED	5	3	2
NUDT11 WILD-TYPE	218	183	101

'NUDT11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S229. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
NUDT11 MUTATED	1	4	2	3
NUDT11 WILD-TYPE	126	115	104	153

'NUDT11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.223 (Fisher's exact test), Q value = 0.88

Table S230. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
NUDT11 MUTATED	2	3	1	0	0	4
NUDT11 WILD-TYPE	97	74	119	57	63	88

'CREBZF MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0243 (Fisher's exact test), Q value = 0.26

Table S231. Gene #20: 'CREBZF MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
CREBZF MUTATED	0	9	0
CREBZF WILD-TYPE	292	423	62

Figure S114. Get High-res Image Gene #20: 'CREBZF MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'CREBZF MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00017 (Fisher's exact test), Q value = 0.0048

Table S232. Gene #20: 'CREBZF MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
CREBZF MUTATED	0	0	0	7
CREBZF WILD-TYPE	153	223	88	154

Figure S115. Get High-res Image Gene #20: 'CREBZF MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'CREBZF MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0259 (Fisher's exact test), Q value = 0.27

Table S233. Gene #20: 'CREBZF MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
CREBZF MUTATED	0	4	4	0
CREBZF WILD-TYPE	185	151	134	95

Figure S116. Get High-res Image Gene #20: 'CREBZF MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'CREBZF MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S234. Gene #20: 'CREBZF MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
CREBZF MUTATED	1	4	3
CREBZF WILD-TYPE	204	216	145

'CREBZF MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0105 (Fisher's exact test), Q value = 0.15

Table S235. Gene #20: 'CREBZF MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
CREBZF MUTATED	2	6	0
CREBZF WILD-TYPE	236	185	228

Figure S117. Get High-res Image Gene #20: 'CREBZF MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'CREBZF MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.068 (Fisher's exact test), Q value = 0.48

Table S236. Gene #20: 'CREBZF MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
CREBZF MUTATED	0	2	6
CREBZF WILD-TYPE	196	189	264

'CREBZF MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.178 (Fisher's exact test), Q value = 0.82

Table S237. Gene #20: 'CREBZF MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
CREBZF MUTATED	0	1	1	5
CREBZF WILD-TYPE	140	106	82	177

'CREBZF MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0136 (Fisher's exact test), Q value = 0.18

Table S238. Gene #20: 'CREBZF MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
CREBZF MUTATED	0	6	1
CREBZF WILD-TYPE	223	180	102

Figure S118. Get High-res Image Gene #20: 'CREBZF MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'CREBZF MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.267 (Fisher's exact test), Q value = 0.91

Table S239. Gene #20: 'CREBZF MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
CREBZF MUTATED	0	1	2	4
CREBZF WILD-TYPE	127	118	104	152

'CREBZF MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.294 (Fisher's exact test), Q value = 0.94

Table S240. Gene #20: 'CREBZF MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
CREBZF MUTATED	0	1	4	0	0	2
CREBZF WILD-TYPE	99	76	116	57	63	90

'SLC26A3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.845 (Fisher's exact test), Q value = 1

Table S241. Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
SLC26A3 MUTATED	1	1	2	2
SLC26A3 WILD-TYPE	77	40	62	55

'SLC26A3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.768 (Fisher's exact test), Q value = 1

Table S242. Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
SLC26A3 MUTATED	2	1	2	1
SLC26A3 WILD-TYPE	61	49	46	78

'SLC26A3 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.58 (Fisher's exact test), Q value = 1

Table S243. Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
SLC26A3 MUTATED	1	4	0	2
SLC26A3 WILD-TYPE	69	94	44	61

'SLC26A3 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.363 (Fisher's exact test), Q value = 1

Table S244. Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
SLC26A3 MUTATED	4	0	3
SLC26A3 WILD-TYPE	134	61	73

'SLC26A3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0038 (Fisher's exact test), Q value = 0.076

Table S245. Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SLC26A3 MUTATED	9	1	1
SLC26A3 WILD-TYPE	283	431	61

Figure S119. Get High-res Image Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'SLC26A3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0153 (Fisher's exact test), Q value = 0.19

Table S246. Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SLC26A3 MUTATED	5	1	0	0
SLC26A3 WILD-TYPE	148	222	88	161

Figure S120. Get High-res Image Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'SLC26A3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.072 (Fisher's exact test), Q value = 0.48

Table S247. Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
SLC26A3 MUTATED	5	0	3	0
SLC26A3 WILD-TYPE	180	155	135	95

'SLC26A3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0648 (Fisher's exact test), Q value = 0.46

Table S248. Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
SLC26A3 MUTATED	6	2	0
SLC26A3 WILD-TYPE	199	218	148

'SLC26A3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0119 (Fisher's exact test), Q value = 0.17

Table S249. Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SLC26A3 MUTATED	7	0	1
SLC26A3 WILD-TYPE	231	191	227

Figure S121. Get High-res Image Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'SLC26A3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00566 (Fisher's exact test), Q value = 0.1

Table S250. Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SLC26A3 MUTATED	6	2	0
SLC26A3 WILD-TYPE	190	189	270

Figure S122. Get High-res Image Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'SLC26A3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0442 (Fisher's exact test), Q value = 0.39

Table S251. Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
SLC26A3 MUTATED	1	3	0	0
SLC26A3 WILD-TYPE	139	104	83	182

Figure S123. Get High-res Image Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'SLC26A3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0272 (Fisher's exact test), Q value = 0.28

Table S252. Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
SLC26A3 MUTATED	1	0	3
SLC26A3 WILD-TYPE	222	186	100

Figure S124. Get High-res Image Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'SLC26A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S253. Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
SLC26A3 MUTATED	1	1	1	1
SLC26A3 WILD-TYPE	126	118	105	155

'SLC26A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.218 (Fisher's exact test), Q value = 0.87

Table S254. Gene #21: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
SLC26A3 MUTATED	1	0	0	0	2	1
SLC26A3 WILD-TYPE	98	77	120	57	61	91

'PLCG1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S255. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
PLCG1 MUTATED	2	0	1	2
PLCG1 WILD-TYPE	76	41	63	55

'PLCG1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.927 (Fisher's exact test), Q value = 1

Table S256. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PLCG1 MUTATED	2	1	1	1
PLCG1 WILD-TYPE	61	49	47	78

'PLCG1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S257. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
PLCG1 MUTATED	2	1	1	1
PLCG1 WILD-TYPE	68	97	43	62

'PLCG1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S258. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PLCG1 MUTATED	2	1	2
PLCG1 WILD-TYPE	136	60	74

'PLCG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0192 (Fisher's exact test), Q value = 0.22

Table S259. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PLCG1 MUTATED	9	2	0
PLCG1 WILD-TYPE	283	430	62

Figure S125. Get High-res Image Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'PLCG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.262 (Fisher's exact test), Q value = 0.91

Table S260. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
PLCG1 MUTATED	4	1	1	1
PLCG1 WILD-TYPE	149	222	87	160

'PLCG1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.233 (Fisher's exact test), Q value = 0.89

Table S261. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PLCG1 MUTATED	1	0	2	2
PLCG1 WILD-TYPE	184	155	136	93

'PLCG1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S262. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PLCG1 MUTATED	2	2	1
PLCG1 WILD-TYPE	203	218	147

'PLCG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.636 (Fisher's exact test), Q value = 1

Table S263. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
PLCG1 MUTATED	4	1	2
PLCG1 WILD-TYPE	234	190	226

'PLCG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.272 (Fisher's exact test), Q value = 0.91

Table S264. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
PLCG1 MUTATED	4	2	1
PLCG1 WILD-TYPE	192	189	269

'PLCG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0313 (Fisher's exact test), Q value = 0.31

Table S265. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
PLCG1 MUTATED	5	0	0	1
PLCG1 WILD-TYPE	135	107	83	181

Figure S126. Get High-res Image Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'PLCG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0645 (Fisher's exact test), Q value = 0.46

Table S266. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
PLCG1 MUTATED	3	0	3
PLCG1 WILD-TYPE	220	186	100

'PLCG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0459 (Fisher's exact test), Q value = 0.4

Table S267. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
PLCG1 MUTATED	3	3	0	0
PLCG1 WILD-TYPE	124	116	106	156

Figure S127. Get High-res Image Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'PLCG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0215 (Fisher's exact test), Q value = 0.24

Table S268. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
PLCG1 MUTATED	0	2	0	0	3	1
PLCG1 WILD-TYPE	99	75	120	57	60	91

Figure S128. Get High-res Image Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'SEMG1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.959 (Fisher's exact test), Q value = 1

Table S269. Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
SEMG1 MUTATED	2	1	3	2
SEMG1 WILD-TYPE	76	40	61	55

'SEMG1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.177 (Fisher's exact test), Q value = 0.82

Table S270. Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
SEMG1 MUTATED	0	2	1	5
SEMG1 WILD-TYPE	63	48	47	74

'SEMG1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.957 (Fisher's exact test), Q value = 1

Table S271. Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
SEMG1 MUTATED	2	4	1	1
SEMG1 WILD-TYPE	68	94	43	62

'SEMG1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S272. Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
SEMG1 MUTATED	4	2	2
SEMG1 WILD-TYPE	134	59	74

'SEMG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00011 (Fisher's exact test), Q value = 0.0034

Table S273. Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SEMG1 MUTATED	11	0	0
SEMG1 WILD-TYPE	281	432	62

Figure S129. Get High-res Image Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'SEMG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00962 (Fisher's exact test), Q value = 0.14

Table S274. Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SEMG1 MUTATED	4	0	0	0
SEMG1 WILD-TYPE	149	223	88	161

Figure S130. Get High-res Image Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'SEMG1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.413 (Fisher's exact test), Q value = 1

Table S275. Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
SEMG1 MUTATED	1	0	2	0
SEMG1 WILD-TYPE	184	155	136	95

'SEMG1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S276. Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
SEMG1 MUTATED	1	2	0
SEMG1 WILD-TYPE	204	218	148

'SEMG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00445 (Fisher's exact test), Q value = 0.087

Table S277. Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SEMG1 MUTATED	6	0	0
SEMG1 WILD-TYPE	232	191	228

Figure S131. Get High-res Image Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'SEMG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00888 (Fisher's exact test), Q value = 0.13

Table S278. Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SEMG1 MUTATED	5	1	0
SEMG1 WILD-TYPE	191	190	270

Figure S132. Get High-res Image Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'SEMG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.155 (Fisher's exact test), Q value = 0.74

Table S279. Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
SEMG1 MUTATED	1	2	0	0
SEMG1 WILD-TYPE	139	105	83	182

'SEMG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.152 (Fisher's exact test), Q value = 0.73

Table S280. Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
SEMG1 MUTATED	1	0	2
SEMG1 WILD-TYPE	222	186	101

'SEMG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.378 (Fisher's exact test), Q value = 1

Table S281. Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
SEMG1 MUTATED	0	2	0	1
SEMG1 WILD-TYPE	127	117	106	155

'SEMG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.592 (Fisher's exact test), Q value = 1

Table S282. Gene #23: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
SEMG1 MUTATED	1	0	0	0	1	1
SEMG1 WILD-TYPE	98	77	120	57	62	91

'NUP210L MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.635 (Fisher's exact test), Q value = 1

Table S283. Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
NUP210L MUTATED	1	2	2	1
NUP210L WILD-TYPE	77	39	62	56

'NUP210L MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.426 (Fisher's exact test), Q value = 1

Table S284. Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
NUP210L MUTATED	0	2	1	3
NUP210L WILD-TYPE	63	48	47	76

'NUP210L MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.327 (Fisher's exact test), Q value = 0.97

Table S285. Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
NUP210L MUTATED	3	3	2	0
NUP210L WILD-TYPE	67	95	42	63

'NUP210L MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S286. Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
NUP210L MUTATED	5	0	3
NUP210L WILD-TYPE	133	61	73

'NUP210L MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0627 (Fisher's exact test), Q value = 0.46

Table S287. Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
NUP210L MUTATED	8	3	0
NUP210L WILD-TYPE	284	429	62

'NUP210L MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00685 (Fisher's exact test), Q value = 0.11

Table S288. Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
NUP210L MUTATED	7	1	0	1
NUP210L WILD-TYPE	146	222	88	160

Figure S133. Get High-res Image Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'NUP210L MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S289. Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
NUP210L MUTATED	2	4	3	0
NUP210L WILD-TYPE	183	151	135	95

'NUP210L MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S290. Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
NUP210L MUTATED	3	4	2
NUP210L WILD-TYPE	202	216	146

'NUP210L MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0303 (Fisher's exact test), Q value = 0.3

Table S291. Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
NUP210L MUTATED	6	2	0
NUP210L WILD-TYPE	232	189	228

Figure S134. Get High-res Image Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'NUP210L MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.207 (Fisher's exact test), Q value = 0.85

Table S292. Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
NUP210L MUTATED	5	1	2
NUP210L WILD-TYPE	191	190	268

'NUP210L MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S293. Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
NUP210L MUTATED	0	2	0	2
NUP210L WILD-TYPE	140	105	83	180

'NUP210L MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0756 (Fisher's exact test), Q value = 0.5

Table S294. Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
NUP210L MUTATED	0	2	2
NUP210L WILD-TYPE	223	184	101

'NUP210L MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.288 (Fisher's exact test), Q value = 0.93

Table S295. Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
NUP210L MUTATED	1	0	0	3
NUP210L WILD-TYPE	126	119	106	153

'NUP210L MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.68 (Fisher's exact test), Q value = 1

Table S296. Gene #24: 'NUP210L MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
NUP210L MUTATED	0	0	2	0	1	1
NUP210L WILD-TYPE	99	77	118	57	62	91

'PDGFRA MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.00923 (Fisher's exact test), Q value = 0.14

Table S297. Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
PDGFRA MUTATED	2	6	1	1
PDGFRA WILD-TYPE	76	35	63	56

Figure S135. Get High-res Image Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'PDGFRA MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.148 (Fisher's exact test), Q value = 0.72

Table S298. Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PDGFRA MUTATED	1	5	2	2
PDGFRA WILD-TYPE	62	45	46	77

'PDGFRA MUTATION STATUS' versus 'MIR_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S299. Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
PDGFRA MUTATED	3	4	2	2
PDGFRA WILD-TYPE	67	94	42	61

'PDGFRA MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.139 (Fisher's exact test), Q value = 0.7

Table S300. Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PDGFRA MUTATED	9	1	1
PDGFRA WILD-TYPE	129	60	75

'PDGFRA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.216 (Fisher's exact test), Q value = 0.87

Table S301. Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PDGFRA MUTATED	11	8	2
PDGFRA WILD-TYPE	281	424	60

'PDGFRA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.274 (Fisher's exact test), Q value = 0.91

Table S302. Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
PDGFRA MUTATED	6	3	1	2
PDGFRA WILD-TYPE	147	220	87	159

'PDGFRA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.22 (Fisher's exact test), Q value = 0.87

Table S303. Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PDGFRA MUTATED	6	1	5	1
PDGFRA WILD-TYPE	179	154	133	94

'PDGFRA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.00797 (Fisher's exact test), Q value = 0.13

Table S304. Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PDGFRA MUTATED	10	1	2
PDGFRA WILD-TYPE	195	219	146

Figure S136. Get High-res Image Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

'PDGFRA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00106 (Fisher's exact test), Q value = 0.025

Table S305. Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
PDGFRA MUTATED	13	1	2
PDGFRA WILD-TYPE	225	190	226

Figure S137. Get High-res Image Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'PDGFRA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0239 (Fisher's exact test), Q value = 0.26

Table S306. Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
PDGFRA MUTATED	9	5	2
PDGFRA WILD-TYPE	187	186	268

Figure S138. Get High-res Image Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00067 (Fisher's exact test), Q value = 0.017

Table S307. Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
PDGFRA MUTATED	1	7	2	0
PDGFRA WILD-TYPE	139	100	81	182

Figure S139. Get High-res Image Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00141 (Fisher's exact test), Q value = 0.032

Table S308. Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
PDGFRA MUTATED	2	1	7
PDGFRA WILD-TYPE	221	185	96

Figure S140. Get High-res Image Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.898 (Fisher's exact test), Q value = 1

Table S309. Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
PDGFRA MUTATED	3	3	2	2
PDGFRA WILD-TYPE	124	116	104	154

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0562 (Fisher's exact test), Q value = 0.44

Table S310. Gene #25: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
PDGFRA MUTATED	0	5	1	1	1	2
PDGFRA WILD-TYPE	99	72	119	56	62	90

'STAG2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.493 (Fisher's exact test), Q value = 1

Table S311. Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
STAG2 MUTATED	4	3	1	2
STAG2 WILD-TYPE	74	38	63	55

'STAG2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S312. Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
STAG2 MUTATED	2	1	3	4
STAG2 WILD-TYPE	61	49	45	75

'STAG2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S313. Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
STAG2 MUTATED	4	6	1	1
STAG2 WILD-TYPE	66	92	43	62

'STAG2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.59 (Fisher's exact test), Q value = 1

Table S314. Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
STAG2 MUTATED	5	2	5
STAG2 WILD-TYPE	133	59	71

'STAG2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00023 (Fisher's exact test), Q value = 0.0064

Table S315. Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
STAG2 MUTATED	14	2	0
STAG2 WILD-TYPE	278	430	62

Figure S141. Get High-res Image Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'STAG2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 6e-05 (Fisher's exact test), Q value = 0.0021

Table S316. Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
STAG2 MUTATED	8	0	1	0
STAG2 WILD-TYPE	145	223	87	161

Figure S142. Get High-res Image Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'STAG2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S317. Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
STAG2 MUTATED	1	3	4	2
STAG2 WILD-TYPE	184	152	134	93

'STAG2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0599 (Fisher's exact test), Q value = 0.45

Table S318. Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
STAG2 MUTATED	7	1	2
STAG2 WILD-TYPE	198	219	146

'STAG2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00045 (Fisher's exact test), Q value = 0.012

Table S319. Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
STAG2 MUTATED	10	1	0
STAG2 WILD-TYPE	228	190	228

Figure S143. Get High-res Image Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'STAG2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00108 (Fisher's exact test), Q value = 0.025

Table S320. Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
STAG2 MUTATED	9	1	1
STAG2 WILD-TYPE	187	190	269

Figure S144. Get High-res Image Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'STAG2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S321. Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
STAG2 MUTATED	1	2	0	1
STAG2 WILD-TYPE	139	105	83	181

'STAG2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0134 (Fisher's exact test), Q value = 0.18

Table S322. Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
STAG2 MUTATED	0	1	3
STAG2 WILD-TYPE	223	185	100

Figure S145. Get High-res Image Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'STAG2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.907 (Fisher's exact test), Q value = 1

Table S323. Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
STAG2 MUTATED	1	1	0	2
STAG2 WILD-TYPE	126	118	106	154

'STAG2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.298 (Fisher's exact test), Q value = 0.94

Table S324. Gene #26: 'STAG2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
STAG2 MUTATED	0	0	1	0	2	1
STAG2 WILD-TYPE	99	77	119	57	61	91

'MED9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.269 (Fisher's exact test), Q value = 0.91

Table S325. Gene #27: 'MED9 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
MED9 MUTATED	1	1	1
MED9 WILD-TYPE	291	431	61

'MED9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.674 (Fisher's exact test), Q value = 1

Table S326. Gene #27: 'MED9 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
MED9 MUTATED	0	1	1	1
MED9 WILD-TYPE	153	222	87	160

'MED9 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.205 (Fisher's exact test), Q value = 0.84

Table S327. Gene #27: 'MED9 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
MED9 MUTATED	0	2	0	1
MED9 WILD-TYPE	185	153	138	94

'MED9 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.267 (Fisher's exact test), Q value = 0.91

Table S328. Gene #27: 'MED9 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
MED9 MUTATED	0	1	2
MED9 WILD-TYPE	205	219	146

'MED9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.202 (Fisher's exact test), Q value = 0.84

Table S329. Gene #27: 'MED9 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
MED9 MUTATED	0	2	1
MED9 WILD-TYPE	238	189	227

'MED9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S330. Gene #27: 'MED9 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
MED9 MUTATED	1	1	1
MED9 WILD-TYPE	195	190	269

'MED9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S331. Gene #27: 'MED9 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
MED9 MUTATED	1	0	0	2
MED9 WILD-TYPE	139	107	83	180

'MED9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S332. Gene #27: 'MED9 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
MED9 MUTATED	1	1	1
MED9 WILD-TYPE	222	185	102

'MED9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S333. Gene #27: 'MED9 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
MED9 MUTATED	1	1	0	1
MED9 WILD-TYPE	126	118	106	155

'MED9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S334. Gene #27: 'MED9 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
MED9 MUTATED	0	0	1	0	1	1
MED9 WILD-TYPE	99	77	119	57	62	91

'NKD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.75 (Fisher's exact test), Q value = 1

Table S335. Gene #28: 'NKD2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
NKD2 MUTATED	1	3	0
NKD2 WILD-TYPE	291	429	62

'NKD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S336. Gene #28: 'NKD2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
NKD2 MUTATED	1	2	0	1
NKD2 WILD-TYPE	152	221	88	160

'NKD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.271 (Fisher's exact test), Q value = 0.91

Table S337. Gene #28: 'NKD2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
NKD2 MUTATED	1	0	3
NKD2 WILD-TYPE	237	191	225

'NKD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S338. Gene #28: 'NKD2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
NKD2 MUTATED	1	1	2
NKD2 WILD-TYPE	195	190	268

'NKD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 0.94

Table S339. Gene #28: 'NKD2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
NKD2 MUTATED	0	2	1	1
NKD2 WILD-TYPE	140	105	82	181

'NKD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S340. Gene #28: 'NKD2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
NKD2 MUTATED	2	1	1
NKD2 WILD-TYPE	221	185	102

'NKD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S341. Gene #28: 'NKD2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
NKD2 MUTATED	1	1	1	1
NKD2 WILD-TYPE	126	118	105	155

'NKD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.694 (Fisher's exact test), Q value = 1

Table S342. Gene #28: 'NKD2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
NKD2 MUTATED	1	0	1	1	1	0
NKD2 WILD-TYPE	98	77	119	56	62	92

'IRS4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.701 (Fisher's exact test), Q value = 1

Table S343. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
IRS4 MUTATED	1	1	0	1
IRS4 WILD-TYPE	77	40	64	56

'IRS4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S344. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
IRS4 MUTATED	1	1	0	1
IRS4 WILD-TYPE	62	49	48	78

'IRS4 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.281 (Fisher's exact test), Q value = 0.92

Table S345. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
IRS4 MUTATED	2	0	0	1
IRS4 WILD-TYPE	68	98	44	62

'IRS4 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.123 (Fisher's exact test), Q value = 0.66

Table S346. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
IRS4 MUTATED	0	1	2
IRS4 WILD-TYPE	138	60	74

'IRS4 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S347. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
IRS4 MUTATED	4	6	1
IRS4 WILD-TYPE	288	426	61

'IRS4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S348. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
IRS4 MUTATED	3	4	1	1
IRS4 WILD-TYPE	150	219	87	160

'IRS4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.661 (Fisher's exact test), Q value = 1

Table S349. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
IRS4 MUTATED	4	2	2	0
IRS4 WILD-TYPE	181	153	136	95

'IRS4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S350. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
IRS4 MUTATED	2	5	1
IRS4 WILD-TYPE	203	215	147

'IRS4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S351. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
IRS4 MUTATED	6	2	3
IRS4 WILD-TYPE	232	189	225

'IRS4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.136 (Fisher's exact test), Q value = 0.7

Table S352. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
IRS4 MUTATED	3	6	2
IRS4 WILD-TYPE	193	185	268

'IRS4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.83

Table S353. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
IRS4 MUTATED	1	4	0	3
IRS4 WILD-TYPE	139	103	83	179

'IRS4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.383 (Fisher's exact test), Q value = 1

Table S354. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
IRS4 MUTATED	2	3	3
IRS4 WILD-TYPE	221	183	100

'IRS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.233 (Fisher's exact test), Q value = 0.89

Table S355. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
IRS4 MUTATED	0	3	1	4
IRS4 WILD-TYPE	127	116	105	152

'IRS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S356. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
IRS4 MUTATED	1	3	1	0	1	2
IRS4 WILD-TYPE	98	74	119	57	62	90

'REN MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 0.94

Table S357. Gene #30: 'REN MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
REN MUTATED	0	0	2	1
REN WILD-TYPE	78	41	62	56

'REN MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.415 (Fisher's exact test), Q value = 1

Table S358. Gene #30: 'REN MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
REN MUTATED	0	0	1	2
REN WILD-TYPE	63	50	47	77

'REN MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.0706 (Fisher's exact test), Q value = 0.48

Table S359. Gene #30: 'REN MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
REN MUTATED	1	1	3	0
REN WILD-TYPE	69	97	41	63

'REN MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S360. Gene #30: 'REN MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
REN MUTATED	4	0	1
REN WILD-TYPE	134	61	75

'REN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00336 (Fisher's exact test), Q value = 0.069

Table S361. Gene #30: 'REN MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
REN MUTATED	7	0	0
REN WILD-TYPE	285	432	62

Figure S146. Get High-res Image Gene #30: 'REN MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'REN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00256 (Fisher's exact test), Q value = 0.056

Table S362. Gene #30: 'REN MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
REN MUTATED	5	0	0	0
REN WILD-TYPE	148	223	88	161

Figure S147. Get High-res Image Gene #30: 'REN MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'REN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S363. Gene #30: 'REN MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
REN MUTATED	1	2	2	1
REN WILD-TYPE	184	153	136	94

'REN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S364. Gene #30: 'REN MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
REN MUTATED	2	3	1
REN WILD-TYPE	203	217	147

'REN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.295 (Fisher's exact test), Q value = 0.94

Table S365. Gene #30: 'REN MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
REN MUTATED	1	2	0
REN WILD-TYPE	237	189	228

'REN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.783 (Fisher's exact test), Q value = 1

Table S366. Gene #30: 'REN MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
REN MUTATED	1	0	2
REN WILD-TYPE	195	191	268

'MUC17 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0638 (Fisher's exact test), Q value = 0.46

Table S367. Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
MUC17 MUTATED	10	4	1	4
MUC17 WILD-TYPE	68	37	63	53

'MUC17 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.192 (Fisher's exact test), Q value = 0.83

Table S368. Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
MUC17 MUTATED	8	1	3	7
MUC17 WILD-TYPE	55	49	45	72

'MUC17 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.802 (Fisher's exact test), Q value = 1

Table S369. Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
MUC17 MUTATED	5	7	3	7
MUC17 WILD-TYPE	65	91	41	56

'MUC17 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.702 (Fisher's exact test), Q value = 1

Table S370. Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
MUC17 MUTATED	10	4	8
MUC17 WILD-TYPE	128	57	68

'MUC17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.379 (Fisher's exact test), Q value = 1

Table S371. Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
MUC17 MUTATED	23	23	4
MUC17 WILD-TYPE	269	409	58

'MUC17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.497 (Fisher's exact test), Q value = 1

Table S372. Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
MUC17 MUTATED	13	13	5	7
MUC17 WILD-TYPE	140	210	83	154

'MUC17 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.205 (Fisher's exact test), Q value = 0.84

Table S373. Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
MUC17 MUTATED	15	8	4	7
MUC17 WILD-TYPE	170	147	134	88

'MUC17 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.371 (Fisher's exact test), Q value = 1

Table S374. Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
MUC17 MUTATED	16	10	8
MUC17 WILD-TYPE	189	210	140

'MUC17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0399 (Fisher's exact test), Q value = 0.36

Table S375. Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
MUC17 MUTATED	20	13	7
MUC17 WILD-TYPE	218	178	221

Figure S148. Get High-res Image Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'MUC17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.179 (Fisher's exact test), Q value = 0.82

Table S376. Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
MUC17 MUTATED	15	14	11
MUC17 WILD-TYPE	181	177	259

'MUC17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0201 (Fisher's exact test), Q value = 0.23

Table S377. Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
MUC17 MUTATED	9	4	0	15
MUC17 WILD-TYPE	131	103	83	167

Figure S149. Get High-res Image Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'MUC17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0323 (Fisher's exact test), Q value = 0.31

Table S378. Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
MUC17 MUTATED	6	13	9
MUC17 WILD-TYPE	217	173	94

Figure S150. Get High-res Image Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'MUC17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0067 (Fisher's exact test), Q value = 0.11

Table S379. Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
MUC17 MUTATED	7	4	1	16
MUC17 WILD-TYPE	120	115	105	140

Figure S151. Get High-res Image Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'MUC17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.685 (Fisher's exact test), Q value = 1

Table S380. Gene #31: 'MUC17 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
MUC17 MUTATED	5	4	10	1	3	5
MUC17 WILD-TYPE	94	73	110	56	60	87

'HTRA2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.195 (Fisher's exact test), Q value = 0.83

Table S381. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
HTRA2 MUTATED	0	5	0
HTRA2 WILD-TYPE	292	427	62

'HTRA2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.579 (Fisher's exact test), Q value = 1

Table S382. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
HTRA2 MUTATED	0	3	1	1
HTRA2 WILD-TYPE	153	220	87	160

'HTRA2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S383. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
HTRA2 MUTATED	3	1	0	0
HTRA2 WILD-TYPE	182	154	138	95

'HTRA2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S384. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
HTRA2 MUTATED	2	1	1
HTRA2 WILD-TYPE	203	219	147

'HTRA2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.745 (Fisher's exact test), Q value = 1

Table S385. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
HTRA2 MUTATED	1	2	2
HTRA2 WILD-TYPE	237	189	226

'HTRA2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.87 (Fisher's exact test), Q value = 1

Table S386. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
HTRA2 MUTATED	1	2	2
HTRA2 WILD-TYPE	195	189	268

'HTRA2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.347 (Fisher's exact test), Q value = 0.99

Table S387. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
HTRA2 MUTATED	3	0	1	1
HTRA2 WILD-TYPE	137	107	82	181

'HTRA2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.726 (Fisher's exact test), Q value = 1

Table S388. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
HTRA2 MUTATED	3	2	0
HTRA2 WILD-TYPE	220	184	103

'HTRA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.674 (Fisher's exact test), Q value = 1

Table S389. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
HTRA2 MUTATED	1	2	0	1
HTRA2 WILD-TYPE	126	117	106	155

'HTRA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.743 (Fisher's exact test), Q value = 1

Table S390. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
HTRA2 MUTATED	2	1	1	0	0	0
HTRA2 WILD-TYPE	97	76	119	57	63	92

'RPL5 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S391. Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
RPL5 MUTATED	2	2	2	0
RPL5 WILD-TYPE	76	39	62	57

'RPL5 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.508 (Fisher's exact test), Q value = 1

Table S392. Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
RPL5 MUTATED	3	0	1	2
RPL5 WILD-TYPE	60	50	47	77

'RPL5 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.908 (Fisher's exact test), Q value = 1

Table S393. Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
RPL5 MUTATED	1	3	1	2
RPL5 WILD-TYPE	69	95	43	61

'RPL5 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.469 (Fisher's exact test), Q value = 1

Table S394. Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
RPL5 MUTATED	3	3	1
RPL5 WILD-TYPE	135	58	75

'RPL5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0503 (Fisher's exact test), Q value = 0.41

Table S395. Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
RPL5 MUTATED	7	2	1
RPL5 WILD-TYPE	285	430	61

'RPL5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.012 (Fisher's exact test), Q value = 0.17

Table S396. Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
RPL5 MUTATED	5	0	0	1
RPL5 WILD-TYPE	148	223	88	160

Figure S152. Get High-res Image Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'RPL5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.49 (Fisher's exact test), Q value = 1

Table S397. Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
RPL5 MUTATED	4	1	2	0
RPL5 WILD-TYPE	181	154	136	95

'RPL5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.801 (Fisher's exact test), Q value = 1

Table S398. Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
RPL5 MUTATED	3	3	1
RPL5 WILD-TYPE	202	217	147

'RPL5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0323 (Fisher's exact test), Q value = 0.31

Table S399. Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
RPL5 MUTATED	5	1	0
RPL5 WILD-TYPE	233	190	228

Figure S153. Get High-res Image Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'RPL5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.187 (Fisher's exact test), Q value = 0.83

Table S400. Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
RPL5 MUTATED	4	1	1
RPL5 WILD-TYPE	192	190	269

'RPL5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0712 (Fisher's exact test), Q value = 0.48

Table S401. Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
RPL5 MUTATED	0	2	1	0
RPL5 WILD-TYPE	140	105	82	182

'RPL5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0524 (Fisher's exact test), Q value = 0.41

Table S402. Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
RPL5 MUTATED	0	1	2
RPL5 WILD-TYPE	223	185	101

'RPL5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S403. Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
RPL5 MUTATED	0	1	1	1
RPL5 WILD-TYPE	127	118	105	155

'RPL5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.133 (Fisher's exact test), Q value = 0.69

Table S404. Gene #33: 'RPL5 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
RPL5 MUTATED	0	0	0	0	1	2
RPL5 WILD-TYPE	99	77	120	57	62	90

'BRAF MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S405. Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
BRAF MUTATED	1	1	2	0
BRAF WILD-TYPE	77	40	62	57

'BRAF MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.71 (Fisher's exact test), Q value = 1

Table S406. Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
BRAF MUTATED	2	0	1	1
BRAF WILD-TYPE	61	50	47	78

'BRAF MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.317 (Fisher's exact test), Q value = 0.95

Table S407. Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
BRAF MUTATED	2	1	0	3
BRAF WILD-TYPE	68	97	44	60

'BRAF MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.0287 (Fisher's exact test), Q value = 0.29

Table S408. Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
BRAF MUTATED	2	4	0
BRAF WILD-TYPE	136	57	76

Figure S154. Get High-res Image Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

'BRAF MUTATION STATUS' versus 'CN_CNMF'

P value = 0.137 (Fisher's exact test), Q value = 0.7

Table S409. Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
BRAF MUTATED	7	3	1
BRAF WILD-TYPE	285	429	61

'BRAF MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00085 (Fisher's exact test), Q value = 0.021

Table S410. Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
BRAF MUTATED	3	0	4	0
BRAF WILD-TYPE	150	223	84	161

Figure S155. Get High-res Image Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'BRAF MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.833 (Fisher's exact test), Q value = 1

Table S411. Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
BRAF MUTATED	3	2	1	2
BRAF WILD-TYPE	182	153	137	93

'BRAF MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.287 (Fisher's exact test), Q value = 0.93

Table S412. Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
BRAF MUTATED	4	1	3
BRAF WILD-TYPE	201	219	145

'BRAF MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0722 (Fisher's exact test), Q value = 0.48

Table S413. Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
BRAF MUTATED	5	3	0
BRAF WILD-TYPE	233	188	228

'BRAF MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.359 (Fisher's exact test), Q value = 1

Table S414. Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
BRAF MUTATED	4	1	3
BRAF WILD-TYPE	192	190	267

'BRAF MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.262 (Fisher's exact test), Q value = 0.91

Table S415. Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
BRAF MUTATED	0	2	0	3
BRAF WILD-TYPE	140	105	83	179

'BRAF MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.091 (Fisher's exact test), Q value = 0.56

Table S416. Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
BRAF MUTATED	0	3	2
BRAF WILD-TYPE	223	183	101

'BRAF MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 0.67

Table S417. Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
BRAF MUTATED	1	0	0	4
BRAF WILD-TYPE	126	119	106	152

'BRAF MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.44 (Fisher's exact test), Q value = 1

Table S418. Gene #34: 'BRAF MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
BRAF MUTATED	0	0	3	0	1	1
BRAF WILD-TYPE	99	77	117	57	62	91

'KDR MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.22 (Fisher's exact test), Q value = 0.87

Table S419. Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
KDR MUTATED	1	2	1	4
KDR WILD-TYPE	77	39	63	53

'KDR MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.655 (Fisher's exact test), Q value = 1

Table S420. Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
KDR MUTATED	1	3	1	3
KDR WILD-TYPE	62	47	47	76

'KDR MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.245 (Fisher's exact test), Q value = 0.9

Table S421. Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
KDR MUTATED	2	1	3	2
KDR WILD-TYPE	68	97	41	61

'KDR MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.513 (Fisher's exact test), Q value = 1

Table S422. Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
KDR MUTATED	6	1	1
KDR WILD-TYPE	132	60	75

'KDR MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0459 (Fisher's exact test), Q value = 0.4

Table S423. Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
KDR MUTATED	9	3	1
KDR WILD-TYPE	283	429	61

Figure S156. Get High-res Image Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'KDR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00784 (Fisher's exact test), Q value = 0.13

Table S424. Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
KDR MUTATED	6	1	1	0
KDR WILD-TYPE	147	222	87	161

Figure S157. Get High-res Image Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'KDR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.87 (Fisher's exact test), Q value = 1

Table S425. Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
KDR MUTATED	4	2	3	1
KDR WILD-TYPE	181	153	135	94

'KDR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0953 (Fisher's exact test), Q value = 0.58

Table S426. Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
KDR MUTATED	7	2	1
KDR WILD-TYPE	198	218	147

'KDR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.144 (Fisher's exact test), Q value = 0.71

Table S427. Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
KDR MUTATED	4	2	0
KDR WILD-TYPE	234	189	228

'KDR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S428. Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
KDR MUTATED	3	1	2
KDR WILD-TYPE	193	190	268

'KDR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.262 (Fisher's exact test), Q value = 0.91

Table S429. Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
KDR MUTATED	0	2	0	3
KDR WILD-TYPE	140	105	83	179

'KDR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0233 (Fisher's exact test), Q value = 0.25

Table S430. Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
KDR MUTATED	0	2	3
KDR WILD-TYPE	223	184	100

Figure S158. Get High-res Image Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'KDR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.288 (Fisher's exact test), Q value = 0.93

Table S431. Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
KDR MUTATED	2	0	0	3
KDR WILD-TYPE	125	119	106	153

'KDR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.336 (Fisher's exact test), Q value = 0.98

Table S432. Gene #35: 'KDR MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
KDR MUTATED	0	0	2	0	2	1
KDR WILD-TYPE	99	77	118	57	61	91

'RBPJ MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0659 (Fisher's exact test), Q value = 0.47

Table S433. Gene #36: 'RBPJ MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
RBPJ MUTATED	0	7	0
RBPJ WILD-TYPE	292	425	62

'RBPJ MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0454 (Fisher's exact test), Q value = 0.4

Table S434. Gene #36: 'RBPJ MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
RBPJ MUTATED	0	1	1	5
RBPJ WILD-TYPE	153	222	87	156

Figure S159. Get High-res Image Gene #36: 'RBPJ MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'RBPJ MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.268 (Fisher's exact test), Q value = 0.91

Table S435. Gene #36: 'RBPJ MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
RBPJ MUTATED	3	0	2	0
RBPJ WILD-TYPE	182	155	136	95

'RBPJ MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.00714 (Fisher's exact test), Q value = 0.12

Table S436. Gene #36: 'RBPJ MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
RBPJ MUTATED	5	0	0
RBPJ WILD-TYPE	200	220	148

Figure S160. Get High-res Image Gene #36: 'RBPJ MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

'RBPJ MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.032 (Fisher's exact test), Q value = 0.31

Table S437. Gene #36: 'RBPJ MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
RBPJ MUTATED	2	5	0
RBPJ WILD-TYPE	236	186	228

Figure S161. Get High-res Image Gene #36: 'RBPJ MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'RBPJ MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.144 (Fisher's exact test), Q value = 0.71

Table S438. Gene #36: 'RBPJ MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
RBPJ MUTATED	0	2	5
RBPJ WILD-TYPE	196	189	265

'RBPJ MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 0.94

Table S439. Gene #36: 'RBPJ MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
RBPJ MUTATED	0	2	1	4
RBPJ WILD-TYPE	140	105	82	178

'RBPJ MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0287 (Fisher's exact test), Q value = 0.29

Table S440. Gene #36: 'RBPJ MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
RBPJ MUTATED	0	5	2
RBPJ WILD-TYPE	223	181	101

Figure S162. Get High-res Image Gene #36: 'RBPJ MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'RBPJ MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S441. Gene #36: 'RBPJ MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
RBPJ MUTATED	1	2	0	4
RBPJ WILD-TYPE	126	117	106	152

'RBPJ MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.231 (Fisher's exact test), Q value = 0.89

Table S442. Gene #36: 'RBPJ MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
RBPJ MUTATED	0	3	2	0	0	2
RBPJ WILD-TYPE	99	74	118	57	63	90

'NRAS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.773 (Fisher's exact test), Q value = 1

Table S443. Gene #37: 'NRAS MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
NRAS MUTATED	1	4	0
NRAS WILD-TYPE	291	428	62

'NRAS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.24 (Fisher's exact test), Q value = 0.89

Table S444. Gene #37: 'NRAS MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
NRAS MUTATED	0	1	0	3
NRAS WILD-TYPE	153	222	88	158

'NRAS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0506 (Fisher's exact test), Q value = 0.41

Table S445. Gene #37: 'NRAS MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
NRAS MUTATED	0	1	1	3
NRAS WILD-TYPE	185	154	137	92

'NRAS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S446. Gene #37: 'NRAS MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
NRAS MUTATED	1	2	2
NRAS WILD-TYPE	204	218	146

'NRAS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0717 (Fisher's exact test), Q value = 0.48

Table S447. Gene #37: 'NRAS MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
NRAS MUTATED	0	3	1
NRAS WILD-TYPE	238	188	227

'NRAS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.313 (Fisher's exact test), Q value = 0.94

Table S448. Gene #37: 'NRAS MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
NRAS MUTATED	0	1	3
NRAS WILD-TYPE	196	190	267

'NRAS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.172 (Fisher's exact test), Q value = 0.8

Table S449. Gene #37: 'NRAS MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
NRAS MUTATED	0	0	2	2
NRAS WILD-TYPE	140	107	81	180

'NRAS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S450. Gene #37: 'NRAS MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
NRAS MUTATED	1	2	1
NRAS WILD-TYPE	222	184	102

'NRAS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S451. Gene #37: 'NRAS MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
NRAS MUTATED	0	1	1	2
NRAS WILD-TYPE	127	118	105	154

'NRAS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.495 (Fisher's exact test), Q value = 1

Table S452. Gene #37: 'NRAS MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
NRAS MUTATED	0	2	1	0	0	1
NRAS WILD-TYPE	99	75	119	57	63	91

'TRERF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S453. Gene #38: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TRERF1 MUTATED	2	4	1
TRERF1 WILD-TYPE	290	428	61

'TRERF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.579 (Fisher's exact test), Q value = 1

Table S454. Gene #38: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TRERF1 MUTATED	2	2	2	1
TRERF1 WILD-TYPE	151	221	86	160

'TRERF1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S455. Gene #38: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TRERF1 MUTATED	2	2	0	2
TRERF1 WILD-TYPE	183	153	138	93

'TRERF1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S456. Gene #38: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TRERF1 MUTATED	3	2	1
TRERF1 WILD-TYPE	202	218	147

'TRERF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S457. Gene #38: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
TRERF1 MUTATED	2	2	2
TRERF1 WILD-TYPE	236	189	226

'TRERF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0185 (Fisher's exact test), Q value = 0.21

Table S458. Gene #38: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
TRERF1 MUTATED	0	5	1
TRERF1 WILD-TYPE	196	186	269

Figure S163. Get High-res Image Gene #38: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'TRERF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.371 (Fisher's exact test), Q value = 1

Table S459. Gene #38: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
TRERF1 MUTATED	1	3	0	2
TRERF1 WILD-TYPE	139	104	83	180

'TRERF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S460. Gene #38: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
TRERF1 MUTATED	2	2	2
TRERF1 WILD-TYPE	221	184	101

'TRERF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.358 (Fisher's exact test), Q value = 1

Table S461. Gene #38: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
TRERF1 MUTATED	1	1	0	4
TRERF1 WILD-TYPE	126	118	106	152

'TRERF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.91 (Fisher's exact test), Q value = 1

Table S462. Gene #38: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
TRERF1 MUTATED	1	1	2	0	0	2
TRERF1 WILD-TYPE	98	76	118	57	63	90

'BCOR MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S463. Gene #39: 'BCOR MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
BCOR MUTATED	1	1	2	3
BCOR WILD-TYPE	77	40	62	54

'BCOR MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.358 (Fisher's exact test), Q value = 1

Table S464. Gene #39: 'BCOR MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
BCOR MUTATED	0	2	2	3
BCOR WILD-TYPE	63	48	46	76

'BCOR MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.105 (Fisher's exact test), Q value = 0.61

Table S465. Gene #39: 'BCOR MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
BCOR MUTATED	0	2	3	2
BCOR WILD-TYPE	70	96	41	61

'BCOR MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.607 (Fisher's exact test), Q value = 1

Table S466. Gene #39: 'BCOR MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
BCOR MUTATED	5	1	1
BCOR WILD-TYPE	133	60	75

'BCOR MUTATION STATUS' versus 'CN_CNMF'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S467. Gene #39: 'BCOR MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
BCOR MUTATED	9	13	0
BCOR WILD-TYPE	283	419	62

'BCOR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.493 (Fisher's exact test), Q value = 1

Table S468. Gene #39: 'BCOR MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
BCOR MUTATED	4	4	2	7
BCOR WILD-TYPE	149	219	86	154

'BCOR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.304 (Fisher's exact test), Q value = 0.94

Table S469. Gene #39: 'BCOR MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
BCOR MUTATED	2	4	6	2
BCOR WILD-TYPE	183	151	132	93

'BCOR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S470. Gene #39: 'BCOR MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
BCOR MUTATED	6	5	3
BCOR WILD-TYPE	199	215	145

'BCOR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.304 (Fisher's exact test), Q value = 0.94

Table S471. Gene #39: 'BCOR MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
BCOR MUTATED	5	8	4
BCOR WILD-TYPE	233	183	224

'BCOR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.364 (Fisher's exact test), Q value = 1

Table S472. Gene #39: 'BCOR MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
BCOR MUTATED	3	4	10
BCOR WILD-TYPE	193	187	260

'BCOR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S473. Gene #39: 'BCOR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
BCOR MUTATED	5	3	1	6
BCOR WILD-TYPE	135	104	82	176

'BCOR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.583 (Fisher's exact test), Q value = 1

Table S474. Gene #39: 'BCOR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
BCOR MUTATED	5	6	4
BCOR WILD-TYPE	218	180	99

'BCOR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.312 (Fisher's exact test), Q value = 0.94

Table S475. Gene #39: 'BCOR MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
BCOR MUTATED	1	5	3	6
BCOR WILD-TYPE	126	114	103	150

'BCOR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.395 (Fisher's exact test), Q value = 1

Table S476. Gene #39: 'BCOR MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
BCOR MUTATED	2	5	4	0	1	3
BCOR WILD-TYPE	97	72	116	57	62	89

'PTPN11 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S477. Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
PTPN11 MUTATED	1	0	1	1
PTPN11 WILD-TYPE	77	41	63	56

'PTPN11 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S478. Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PTPN11 MUTATED	1	0	0	2
PTPN11 WILD-TYPE	62	50	48	77

'PTPN11 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 0.69

Table S479. Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
PTPN11 MUTATED	1	0	2	1
PTPN11 WILD-TYPE	69	98	42	62

'PTPN11 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S480. Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PTPN11 MUTATED	2	1	1
PTPN11 WILD-TYPE	136	60	75

'PTPN11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S481. Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PTPN11 MUTATED	5	4	1
PTPN11 WILD-TYPE	287	428	61

'PTPN11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0788 (Fisher's exact test), Q value = 0.51

Table S482. Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
PTPN11 MUTATED	4	1	3	1
PTPN11 WILD-TYPE	149	222	85	160

'PTPN11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.388 (Fisher's exact test), Q value = 1

Table S483. Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PTPN11 MUTATED	3	1	1	3
PTPN11 WILD-TYPE	182	154	137	92

'PTPN11 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.231 (Fisher's exact test), Q value = 0.89

Table S484. Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PTPN11 MUTATED	5	1	2
PTPN11 WILD-TYPE	200	219	146

'PTPN11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 0.94

Table S485. Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
PTPN11 MUTATED	5	3	1
PTPN11 WILD-TYPE	233	188	227

'PTPN11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.266 (Fisher's exact test), Q value = 0.91

Table S486. Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
PTPN11 MUTATED	5	2	2
PTPN11 WILD-TYPE	191	189	268

'PTPN11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.233 (Fisher's exact test), Q value = 0.89

Table S487. Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
PTPN11 MUTATED	3	3	0	1
PTPN11 WILD-TYPE	137	104	83	181

'PTPN11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00541 (Fisher's exact test), Q value = 0.099

Table S488. Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
PTPN11 MUTATED	1	1	5
PTPN11 WILD-TYPE	222	185	98

Figure S164. Get High-res Image Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'PTPN11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 0.83

Table S489. Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
PTPN11 MUTATED	4	2	0	1
PTPN11 WILD-TYPE	123	117	106	155

'PTPN11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00178 (Fisher's exact test), Q value = 0.04

Table S490. Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
PTPN11 MUTATED	1	0	1	0	5	0
PTPN11 WILD-TYPE	98	77	119	57	58	92

Figure S165. Get High-res Image Gene #40: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MX2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.549 (Fisher's exact test), Q value = 1

Table S491. Gene #41: 'MX2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
MX2 MUTATED	2	0	2	0
MX2 WILD-TYPE	76	41	62	57

'MX2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S492. Gene #41: 'MX2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
MX2 MUTATED	1	0	1	2
MX2 WILD-TYPE	62	50	47	77

'MX2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.331 (Fisher's exact test), Q value = 0.97

Table S493. Gene #41: 'MX2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
MX2 MUTATED	2	0	1	1
MX2 WILD-TYPE	68	98	43	62

'MX2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.443 (Fisher's exact test), Q value = 1

Table S494. Gene #41: 'MX2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
MX2 MUTATED	1	1	2
MX2 WILD-TYPE	137	60	74

'MX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.252 (Fisher's exact test), Q value = 0.9

Table S495. Gene #41: 'MX2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
MX2 MUTATED	6	3	0
MX2 WILD-TYPE	286	429	62

'MX2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.657 (Fisher's exact test), Q value = 1

Table S496. Gene #41: 'MX2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
MX2 MUTATED	2	1	0	2
MX2 WILD-TYPE	151	222	88	159

'MX2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.895 (Fisher's exact test), Q value = 1

Table S497. Gene #41: 'MX2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
MX2 MUTATED	3	1	1	1
MX2 WILD-TYPE	182	154	137	94

'MX2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.402 (Fisher's exact test), Q value = 1

Table S498. Gene #41: 'MX2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
MX2 MUTATED	3	3	0
MX2 WILD-TYPE	202	217	148

'MX2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S499. Gene #41: 'MX2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
MX2 MUTATED	1	1	2
MX2 WILD-TYPE	237	190	226

'MX2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S500. Gene #41: 'MX2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
MX2 MUTATED	1	1	2
MX2 WILD-TYPE	195	190	268

'MX2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 0.94

Table S501. Gene #41: 'MX2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
MX2 MUTATED	0	2	1	1
MX2 WILD-TYPE	140	105	82	181

'MX2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S502. Gene #41: 'MX2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
MX2 MUTATED	2	1	1
MX2 WILD-TYPE	221	185	102

'MX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S503. Gene #41: 'MX2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
MX2 MUTATED	1	2	0	1
MX2 WILD-TYPE	126	117	106	155

'MX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.53 (Fisher's exact test), Q value = 1

Table S504. Gene #41: 'MX2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
MX2 MUTATED	0	1	1	1	1	0
MX2 WILD-TYPE	99	76	119	56	62	92

'FAM47C MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 0.94

Table S505. Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
FAM47C MUTATED	0	0	2	1
FAM47C WILD-TYPE	78	41	62	56

'FAM47C MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0583 (Fisher's exact test), Q value = 0.44

Table S506. Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
FAM47C MUTATED	0	1	2	0
FAM47C WILD-TYPE	63	49	46	79

'FAM47C MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.349 (Fisher's exact test), Q value = 0.99

Table S507. Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
FAM47C MUTATED	0	2	2	1
FAM47C WILD-TYPE	70	96	42	62

'FAM47C MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S508. Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
FAM47C MUTATED	2	1	2
FAM47C WILD-TYPE	136	60	74

'FAM47C MUTATION STATUS' versus 'CN_CNMF'

P value = 0.571 (Fisher's exact test), Q value = 1

Table S509. Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
FAM47C MUTATED	6	15	2
FAM47C WILD-TYPE	286	417	60

'FAM47C MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.561 (Fisher's exact test), Q value = 1

Table S510. Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
FAM47C MUTATED	3	7	4	7
FAM47C WILD-TYPE	150	216	84	154

'FAM47C MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S511. Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
FAM47C MUTATED	6	7	4	2
FAM47C WILD-TYPE	179	148	134	93

'FAM47C MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.562 (Fisher's exact test), Q value = 1

Table S512. Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
FAM47C MUTATED	6	6	7
FAM47C WILD-TYPE	199	214	141

'FAM47C MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0757 (Fisher's exact test), Q value = 0.5

Table S513. Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
FAM47C MUTATED	5	11	5
FAM47C WILD-TYPE	233	180	223

'FAM47C MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00306 (Fisher's exact test), Q value = 0.064

Table S514. Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
FAM47C MUTATED	4	1	16
FAM47C WILD-TYPE	192	190	254

Figure S166. Get High-res Image Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'FAM47C MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.437 (Fisher's exact test), Q value = 1

Table S515. Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
FAM47C MUTATED	3	4	2	10
FAM47C WILD-TYPE	137	103	81	172

'FAM47C MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0621 (Fisher's exact test), Q value = 0.46

Table S516. Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
FAM47C MUTATED	5	12	2
FAM47C WILD-TYPE	218	174	101

'FAM47C MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00097 (Fisher's exact test), Q value = 0.024

Table S517. Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
FAM47C MUTATED	0	2	4	13
FAM47C WILD-TYPE	127	117	102	143

Figure S167. Get High-res Image Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'FAM47C MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00523 (Fisher's exact test), Q value = 0.097

Table S518. Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
FAM47C MUTATED	0	1	8	1	1	8
FAM47C WILD-TYPE	99	76	112	56	62	84

Figure S168. Get High-res Image Gene #42: 'FAM47C MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'DDX5 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.412 (Fisher's exact test), Q value = 1

Table S519. Gene #43: 'DDX5 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
DDX5 MUTATED	1	0	0	2
DDX5 WILD-TYPE	77	41	64	55

'DDX5 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S520. Gene #43: 'DDX5 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
DDX5 MUTATED	1	1	0	1
DDX5 WILD-TYPE	62	49	48	78

'DDX5 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.646 (Fisher's exact test), Q value = 1

Table S521. Gene #43: 'DDX5 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
DDX5 MUTATED	0	2	1	1
DDX5 WILD-TYPE	70	96	43	62

'DDX5 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S522. Gene #43: 'DDX5 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
DDX5 MUTATED	1	1	2
DDX5 WILD-TYPE	137	60	74

'DDX5 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S523. Gene #43: 'DDX5 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
DDX5 MUTATED	4	5	0
DDX5 WILD-TYPE	288	427	62

'DDX5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.602 (Fisher's exact test), Q value = 1

Table S524. Gene #43: 'DDX5 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
DDX5 MUTATED	3	2	0	2
DDX5 WILD-TYPE	150	221	88	159

'DDX5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S525. Gene #43: 'DDX5 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
DDX5 MUTATED	4	1	1	1
DDX5 WILD-TYPE	181	154	137	94

'DDX5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.562 (Fisher's exact test), Q value = 1

Table S526. Gene #43: 'DDX5 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
DDX5 MUTATED	4	2	1
DDX5 WILD-TYPE	201	218	147

'DDX5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S527. Gene #43: 'DDX5 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
DDX5 MUTATED	2	1	3
DDX5 WILD-TYPE	236	190	225

'DDX5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S528. Gene #43: 'DDX5 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
DDX5 MUTATED	1	3	2
DDX5 WILD-TYPE	195	188	268

'DDX5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 0.91

Table S529. Gene #43: 'DDX5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
DDX5 MUTATED	0	2	0	3
DDX5 WILD-TYPE	140	105	83	179

'DDX5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.524 (Fisher's exact test), Q value = 1

Table S530. Gene #43: 'DDX5 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
DDX5 MUTATED	1	3	1
DDX5 WILD-TYPE	222	183	102

'DDX5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.653 (Fisher's exact test), Q value = 1

Table S531. Gene #43: 'DDX5 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
DDX5 MUTATED	1	1	0	3
DDX5 WILD-TYPE	126	118	106	153

'DDX5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.293 (Fisher's exact test), Q value = 0.93

Table S532. Gene #43: 'DDX5 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
DDX5 MUTATED	0	1	1	0	0	3
DDX5 WILD-TYPE	99	76	119	57	63	89

'SETD2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.106 (Fisher's exact test), Q value = 0.61

Table S533. Gene #44: 'SETD2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
SETD2 MUTATED	1	2	0	0
SETD2 WILD-TYPE	77	39	64	57

'SETD2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.35 (Fisher's exact test), Q value = 0.99

Table S534. Gene #44: 'SETD2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
SETD2 MUTATED	2	1	0	0
SETD2 WILD-TYPE	61	49	48	79

'SETD2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.391 (Fisher's exact test), Q value = 1

Table S535. Gene #44: 'SETD2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
SETD2 MUTATED	1	0	1	1
SETD2 WILD-TYPE	69	98	43	62

'SETD2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S536. Gene #44: 'SETD2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
SETD2 MUTATED	2	0	1
SETD2 WILD-TYPE	136	61	75

'SETD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0856 (Fisher's exact test), Q value = 0.54

Table S537. Gene #44: 'SETD2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SETD2 MUTATED	5	5	3
SETD2 WILD-TYPE	287	427	59

'SETD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 0.99

Table S538. Gene #44: 'SETD2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SETD2 MUTATED	5	3	3	2
SETD2 WILD-TYPE	148	220	85	159

'SETD2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.872 (Fisher's exact test), Q value = 1

Table S539. Gene #44: 'SETD2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
SETD2 MUTATED	4	2	3	1
SETD2 WILD-TYPE	181	153	135	94

'SETD2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S540. Gene #44: 'SETD2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
SETD2 MUTATED	5	4	1
SETD2 WILD-TYPE	200	216	147

'SETD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0677 (Fisher's exact test), Q value = 0.48

Table S541. Gene #44: 'SETD2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SETD2 MUTATED	9	2	2
SETD2 WILD-TYPE	229	189	226

'SETD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S542. Gene #44: 'SETD2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SETD2 MUTATED	5	5	3
SETD2 WILD-TYPE	191	186	267

'SETD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.365 (Fisher's exact test), Q value = 1

Table S543. Gene #44: 'SETD2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
SETD2 MUTATED	1	4	2	3
SETD2 WILD-TYPE	139	103	81	179

'SETD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0919 (Fisher's exact test), Q value = 0.57

Table S544. Gene #44: 'SETD2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
SETD2 MUTATED	3	2	5
SETD2 WILD-TYPE	220	184	98

'SETD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.256 (Fisher's exact test), Q value = 0.91

Table S545. Gene #44: 'SETD2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
SETD2 MUTATED	2	4	0	4
SETD2 WILD-TYPE	125	115	106	152

'SETD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.809 (Fisher's exact test), Q value = 1

Table S546. Gene #44: 'SETD2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
SETD2 MUTATED	1	3	3	1	1	1
SETD2 WILD-TYPE	98	74	117	56	62	91

'ZNF709 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S547. Gene #45: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ZNF709 MUTATED	2	3	0
ZNF709 WILD-TYPE	290	429	62

'ZNF709 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.83

Table S548. Gene #45: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ZNF709 MUTATED	0	1	2	1
ZNF709 WILD-TYPE	153	222	86	160

'ZNF709 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.548 (Fisher's exact test), Q value = 1

Table S549. Gene #45: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ZNF709 MUTATED	2	2	0	0
ZNF709 WILD-TYPE	183	153	138	95

'ZNF709 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.572 (Fisher's exact test), Q value = 1

Table S550. Gene #45: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ZNF709 MUTATED	1	1	2
ZNF709 WILD-TYPE	204	219	146

'ZNF709 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 1

Table S551. Gene #45: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
ZNF709 MUTATED	1	2	1
ZNF709 WILD-TYPE	237	189	227

'ZNF709 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S552. Gene #45: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
ZNF709 MUTATED	1	1	2
ZNF709 WILD-TYPE	195	190	268

'ZNF709 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S553. Gene #45: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
ZNF709 MUTATED	1	0	0	2
ZNF709 WILD-TYPE	139	107	83	180

'ZNF709 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S554. Gene #45: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
ZNF709 MUTATED	1	2	0
ZNF709 WILD-TYPE	222	184	103

'ZNF709 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S555. Gene #45: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
ZNF709 MUTATED	2	0	0	1
ZNF709 WILD-TYPE	125	119	106	155

'ZNF709 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.565 (Fisher's exact test), Q value = 1

Table S556. Gene #45: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
ZNF709 MUTATED	0	1	2	0	0	0
ZNF709 WILD-TYPE	99	76	118	57	63	92

'FAM126B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.241 (Fisher's exact test), Q value = 0.89

Table S557. Gene #46: 'FAM126B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
FAM126B MUTATED	1	0	3	0
FAM126B WILD-TYPE	77	41	61	57

'FAM126B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0298 (Fisher's exact test), Q value = 0.3

Table S558. Gene #46: 'FAM126B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
FAM126B MUTATED	1	0	3	0
FAM126B WILD-TYPE	62	50	45	79

Figure S169. Get High-res Image Gene #46: 'FAM126B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'FAM126B MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S559. Gene #46: 'FAM126B MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
FAM126B MUTATED	2	2	0	0
FAM126B WILD-TYPE	68	96	44	63

'FAM126B MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.447 (Fisher's exact test), Q value = 1

Table S560. Gene #46: 'FAM126B MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
FAM126B MUTATED	1	1	2
FAM126B WILD-TYPE	137	60	74

'FAM126B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.142 (Fisher's exact test), Q value = 0.71

Table S561. Gene #46: 'FAM126B MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
FAM126B MUTATED	5	2	1
FAM126B WILD-TYPE	287	430	61

'FAM126B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.757 (Fisher's exact test), Q value = 1

Table S562. Gene #46: 'FAM126B MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
FAM126B MUTATED	2	1	0	1
FAM126B WILD-TYPE	151	222	88	160

'FAM126B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.505 (Fisher's exact test), Q value = 1

Table S563. Gene #46: 'FAM126B MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
FAM126B MUTATED	2	1	3	0
FAM126B WILD-TYPE	183	154	135	95

'FAM126B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.771 (Fisher's exact test), Q value = 1

Table S564. Gene #46: 'FAM126B MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
FAM126B MUTATED	3	2	1
FAM126B WILD-TYPE	202	218	147

'FAM126B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S565. Gene #46: 'FAM126B MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
FAM126B MUTATED	3	0	1
FAM126B WILD-TYPE	235	191	227

'FAM126B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S566. Gene #46: 'FAM126B MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
FAM126B MUTATED	1	2	1
FAM126B WILD-TYPE	195	189	269

'FAM126B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.197 (Fisher's exact test), Q value = 0.83

Table S567. Gene #46: 'FAM126B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
FAM126B MUTATED	1	2	1	0
FAM126B WILD-TYPE	139	105	82	182

'FAM126B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.196 (Fisher's exact test), Q value = 0.83

Table S568. Gene #46: 'FAM126B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
FAM126B MUTATED	2	0	2
FAM126B WILD-TYPE	221	186	101

'FAM126B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.575 (Fisher's exact test), Q value = 1

Table S569. Gene #46: 'FAM126B MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
FAM126B MUTATED	0	2	1	1
FAM126B WILD-TYPE	127	117	105	155

'FAM126B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.649 (Fisher's exact test), Q value = 1

Table S570. Gene #46: 'FAM126B MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
FAM126B MUTATED	1	1	0	1	0	1
FAM126B WILD-TYPE	98	76	120	56	63	91

'MYST4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 0.9

Table S571. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
MYST4 MUTATED	2	9	1
MYST4 WILD-TYPE	290	423	61

'MYST4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0608 (Fisher's exact test), Q value = 0.45

Table S572. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
MYST4 MUTATED	3	2	0	7
MYST4 WILD-TYPE	150	221	88	154

'MYST4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 0.67

Table S573. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
MYST4 MUTATED	6	2	0	2
MYST4 WILD-TYPE	179	153	138	93

'MYST4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.279 (Fisher's exact test), Q value = 0.92

Table S574. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
MYST4 MUTATED	6	3	1
MYST4 WILD-TYPE	199	217	147

'MYST4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.353 (Fisher's exact test), Q value = 1

Table S575. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
MYST4 MUTATED	2	5	4
MYST4 WILD-TYPE	236	186	224

'MYST4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.219 (Fisher's exact test), Q value = 0.87

Table S576. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
MYST4 MUTATED	1	3	7
MYST4 WILD-TYPE	195	188	263

'MYST4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 0.83

Table S577. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
MYST4 MUTATED	1	3	4	3
MYST4 WILD-TYPE	139	104	79	179

'MYST4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S578. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
MYST4 MUTATED	5	4	2
MYST4 WILD-TYPE	218	182	101

'MYST4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0721 (Fisher's exact test), Q value = 0.48

Table S579. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
MYST4 MUTATED	0	2	5	4
MYST4 WILD-TYPE	127	117	101	152

'MYST4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S580. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
MYST4 MUTATED	1	2	2	1	1	4
MYST4 WILD-TYPE	98	75	118	56	62	88

'TLR6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.128 (Fisher's exact test), Q value = 0.67

Table S581. Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
TLR6 MUTATED	0	0	3	1
TLR6 WILD-TYPE	78	41	61	56

'TLR6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0477 (Fisher's exact test), Q value = 0.4

Table S582. Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
TLR6 MUTATED	0	0	3	1
TLR6 WILD-TYPE	63	50	45	78

Figure S170. Get High-res Image Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'TLR6 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S583. Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
TLR6 MUTATED	0	2	1	2
TLR6 WILD-TYPE	70	96	43	61

'TLR6 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.291 (Fisher's exact test), Q value = 0.93

Table S584. Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TLR6 MUTATED	1	2	2
TLR6 WILD-TYPE	137	59	74

'TLR6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 0.64

Table S585. Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TLR6 MUTATED	6	2	0
TLR6 WILD-TYPE	286	430	62

'TLR6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0243 (Fisher's exact test), Q value = 0.26

Table S586. Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TLR6 MUTATED	2	0	2	0
TLR6 WILD-TYPE	151	223	86	161

Figure S171. Get High-res Image Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'TLR6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S587. Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TLR6 MUTATED	1	1	1	1
TLR6 WILD-TYPE	184	154	137	94

'TLR6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S588. Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TLR6 MUTATED	1	2	1
TLR6 WILD-TYPE	204	218	147

'TLR6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.463 (Fisher's exact test), Q value = 1

Table S589. Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
TLR6 MUTATED	2	2	0
TLR6 WILD-TYPE	236	189	228

'TLR6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.569 (Fisher's exact test), Q value = 1

Table S590. Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
TLR6 MUTATED	2	0	2
TLR6 WILD-TYPE	194	191	268

'TLR6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.237 (Fisher's exact test), Q value = 0.89

Table S591. Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
TLR6 MUTATED	0	0	0	3
TLR6 WILD-TYPE	140	107	83	179

'TLR6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.231 (Fisher's exact test), Q value = 0.89

Table S592. Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
TLR6 MUTATED	0	2	1
TLR6 WILD-TYPE	223	184	102

'TLR6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.63 (Fisher's exact test), Q value = 1

Table S593. Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
TLR6 MUTATED	1	0	0	2
TLR6 WILD-TYPE	126	119	106	154

'TLR6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S594. Gene #48: 'TLR6 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
TLR6 MUTATED	0	0	2	0	1	0
TLR6 WILD-TYPE	99	77	118	57	62	92

'EGFR MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0858 (Fisher's exact test), Q value = 0.54

Table S595. Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
EGFR MUTATED	26	8	23	11
EGFR WILD-TYPE	52	33	41	46

'EGFR MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0565 (Fisher's exact test), Q value = 0.44

Table S596. Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
EGFR MUTATED	18	7	17	26
EGFR WILD-TYPE	45	43	31	53

'EGFR MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 0.92

Table S597. Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
EGFR MUTATED	19	31	7	17
EGFR WILD-TYPE	51	67	37	46

'EGFR MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.138 (Fisher's exact test), Q value = 0.7

Table S598. Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
EGFR MUTATED	30	19	25
EGFR WILD-TYPE	108	42	51

'EGFR MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S599. Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
EGFR MUTATED	95	9	3
EGFR WILD-TYPE	197	423	59

Figure S172. Get High-res Image Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'EGFR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S600. Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
EGFR MUTATED	45	0	9	2
EGFR WILD-TYPE	108	223	79	159

Figure S173. Get High-res Image Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'EGFR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.313 (Fisher's exact test), Q value = 0.94

Table S601. Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
EGFR MUTATED	25	14	18	7
EGFR WILD-TYPE	160	141	120	88

'EGFR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0189 (Fisher's exact test), Q value = 0.22

Table S602. Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
EGFR MUTATED	18	35	11
EGFR WILD-TYPE	187	185	137

Figure S174. Get High-res Image Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

'EGFR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S603. Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
EGFR MUTATED	71	9	0
EGFR WILD-TYPE	167	182	228

Figure S175. Get High-res Image Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'EGFR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S604. Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
EGFR MUTATED	69	2	9
EGFR WILD-TYPE	127	189	261

Figure S176. Get High-res Image Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'EGFR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0112 (Fisher's exact test), Q value = 0.16

Table S605. Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
EGFR MUTATED	11	11	0	13
EGFR WILD-TYPE	129	96	83	169

Figure S177. Get High-res Image Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'EGFR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S606. Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
EGFR MUTATED	1	9	25
EGFR WILD-TYPE	222	177	78

Figure S178. Get High-res Image Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'EGFR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 9e-05 (Fisher's exact test), Q value = 0.0029

Table S607. Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
EGFR MUTATED	6	17	0	12
EGFR WILD-TYPE	121	102	106	144

Figure S179. Get High-res Image Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'EGFR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S608. Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
EGFR MUTATED	0	1	8	0	24	2
EGFR WILD-TYPE	99	76	112	57	39	90

Figure S180. Get High-res Image Gene #49: 'EGFR MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ACADS MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.62 (Fisher's exact test), Q value = 1

Table S609. Gene #50: 'ACADS MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
ACADS MUTATED	2	0	0	1
ACADS WILD-TYPE	76	41	64	56

'ACADS MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.349 (Fisher's exact test), Q value = 0.99

Table S610. Gene #50: 'ACADS MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
ACADS MUTATED	2	1	0	0
ACADS WILD-TYPE	61	49	48	79

'ACADS MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.28 (Fisher's exact test), Q value = 0.92

Table S611. Gene #50: 'ACADS MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
ACADS MUTATED	2	0	0	1
ACADS WILD-TYPE	68	98	44	62

'ACADS MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S612. Gene #50: 'ACADS MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
ACADS MUTATED	1	1	1
ACADS WILD-TYPE	137	60	75

'ACADS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.147 (Fisher's exact test), Q value = 0.72

Table S613. Gene #50: 'ACADS MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ACADS MUTATED	3	1	1
ACADS WILD-TYPE	289	431	61

'ACADS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.018 (Fisher's exact test), Q value = 0.21

Table S614. Gene #50: 'ACADS MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ACADS MUTATED	3	0	0	0
ACADS WILD-TYPE	150	223	88	161

Figure S181. Get High-res Image Gene #50: 'ACADS MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'TNRC18 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S615. Gene #51: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TNRC18 MUTATED	3	9	0
TNRC18 WILD-TYPE	289	423	62

'TNRC18 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.436 (Fisher's exact test), Q value = 1

Table S616. Gene #51: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TNRC18 MUTATED	2	6	2	1
TNRC18 WILD-TYPE	151	217	86	160

'TNRC18 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.513 (Fisher's exact test), Q value = 1

Table S617. Gene #51: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TNRC18 MUTATED	3	4	2	0
TNRC18 WILD-TYPE	182	151	136	95

'TNRC18 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S618. Gene #51: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TNRC18 MUTATED	4	2	3
TNRC18 WILD-TYPE	201	218	145

'TNRC18 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 0.94

Table S619. Gene #51: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
TNRC18 MUTATED	3	6	3
TNRC18 WILD-TYPE	235	185	225

'TNRC18 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.62 (Fisher's exact test), Q value = 1

Table S620. Gene #51: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
TNRC18 MUTATED	2	4	6
TNRC18 WILD-TYPE	194	187	264

'TNRC18 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 1

Table S621. Gene #51: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
TNRC18 MUTATED	4	2	0	4
TNRC18 WILD-TYPE	136	105	83	178

'TNRC18 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S622. Gene #51: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
TNRC18 MUTATED	3	4	3
TNRC18 WILD-TYPE	220	182	100

'TNRC18 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.357 (Fisher's exact test), Q value = 1

Table S623. Gene #51: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
TNRC18 MUTATED	4	2	0	3
TNRC18 WILD-TYPE	123	117	106	153

'TNRC18 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S624. Gene #51: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
TNRC18 MUTATED	1	1	4	0	1	2
TNRC18 WILD-TYPE	98	76	116	57	62	90

'SLC6A3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S625. Gene #52: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
SLC6A3 MUTATED	0	1	1	1
SLC6A3 WILD-TYPE	78	40	63	56

'SLC6A3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.701 (Fisher's exact test), Q value = 1

Table S626. Gene #52: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
SLC6A3 MUTATED	0	1	1	1
SLC6A3 WILD-TYPE	63	49	47	78

'SLC6A3 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S627. Gene #52: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
SLC6A3 MUTATED	0	2	1	0
SLC6A3 WILD-TYPE	70	96	43	63

'SLC6A3 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S628. Gene #52: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
SLC6A3 MUTATED	2	0	1
SLC6A3 WILD-TYPE	136	61	75

'SLC6A3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.37 (Fisher's exact test), Q value = 1

Table S629. Gene #52: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SLC6A3 MUTATED	3	7	2
SLC6A3 WILD-TYPE	289	425	60

'SLC6A3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.743 (Fisher's exact test), Q value = 1

Table S630. Gene #52: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SLC6A3 MUTATED	3	4	0	3
SLC6A3 WILD-TYPE	150	219	88	158

'SLC6A3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 0.69

Table S631. Gene #52: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
SLC6A3 MUTATED	6	1	1	0
SLC6A3 WILD-TYPE	179	154	137	95

'SLC6A3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.064 (Fisher's exact test), Q value = 0.46

Table S632. Gene #52: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
SLC6A3 MUTATED	6	2	0
SLC6A3 WILD-TYPE	199	218	148

'SLC6A3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.924 (Fisher's exact test), Q value = 1

Table S633. Gene #52: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SLC6A3 MUTATED	3	3	4
SLC6A3 WILD-TYPE	235	188	224

'SLC6A3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.728 (Fisher's exact test), Q value = 1

Table S634. Gene #52: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SLC6A3 MUTATED	2	4	4
SLC6A3 WILD-TYPE	194	187	266

'SLC6A3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.183 (Fisher's exact test), Q value = 0.83

Table S635. Gene #52: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
SLC6A3 MUTATED	2	4	2	1
SLC6A3 WILD-TYPE	138	103	81	181

'SLC6A3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.504 (Fisher's exact test), Q value = 1

Table S636. Gene #52: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
SLC6A3 MUTATED	4	2	3
SLC6A3 WILD-TYPE	219	184	100

'SLC6A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S637. Gene #52: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
SLC6A3 MUTATED	2	1	2	4
SLC6A3 WILD-TYPE	125	118	104	152

'SLC6A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.217 (Fisher's exact test), Q value = 0.87

Table S638. Gene #52: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
SLC6A3 MUTATED	3	0	1	0	1	4
SLC6A3 WILD-TYPE	96	77	119	57	62	88

'ZNF292 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 0.94

Table S639. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
ZNF292 MUTATED	0	0	2	1
ZNF292 WILD-TYPE	78	41	62	56

'ZNF292 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.223 (Fisher's exact test), Q value = 0.88

Table S640. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
ZNF292 MUTATED	0	0	2	1
ZNF292 WILD-TYPE	63	50	46	78

'ZNF292 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S641. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
ZNF292 MUTATED	0	2	1	0
ZNF292 WILD-TYPE	70	96	43	63

'ZNF292 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.311 (Fisher's exact test), Q value = 0.94

Table S642. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
ZNF292 MUTATED	1	0	2
ZNF292 WILD-TYPE	137	61	74

'ZNF292 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.238 (Fisher's exact test), Q value = 0.89

Table S643. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ZNF292 MUTATED	4	13	0
ZNF292 WILD-TYPE	288	419	62

'ZNF292 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.144 (Fisher's exact test), Q value = 0.71

Table S644. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ZNF292 MUTATED	2	4	1	8
ZNF292 WILD-TYPE	151	219	87	153

'ZNF292 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.427 (Fisher's exact test), Q value = 1

Table S645. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ZNF292 MUTATED	4	7	3	1
ZNF292 WILD-TYPE	181	148	135	94

'ZNF292 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.802 (Fisher's exact test), Q value = 1

Table S646. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ZNF292 MUTATED	5	5	5
ZNF292 WILD-TYPE	200	215	143

'ZNF292 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.131 (Fisher's exact test), Q value = 0.69

Table S647. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
ZNF292 MUTATED	3	8	4
ZNF292 WILD-TYPE	235	183	224

'ZNF292 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0855 (Fisher's exact test), Q value = 0.54

Table S648. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
ZNF292 MUTATED	1	5	9
ZNF292 WILD-TYPE	195	186	261

'ZNF292 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S649. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
ZNF292 MUTATED	2	3	1	8
ZNF292 WILD-TYPE	138	104	82	174

'ZNF292 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.31 (Fisher's exact test), Q value = 0.94

Table S650. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
ZNF292 MUTATED	4	8	2
ZNF292 WILD-TYPE	219	178	101

'ZNF292 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.156 (Fisher's exact test), Q value = 0.74

Table S651. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
ZNF292 MUTATED	1	2	3	8
ZNF292 WILD-TYPE	126	117	103	148

'ZNF292 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0466 (Fisher's exact test), Q value = 0.4

Table S652. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
ZNF292 MUTATED	0	2	5	1	0	6
ZNF292 WILD-TYPE	99	75	115	56	63	86

Figure S182. Get High-res Image Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ARID2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S653. Gene #54: 'ARID2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ARID2 MUTATED	4	9	0
ARID2 WILD-TYPE	288	423	62

'ARID2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.82 (Fisher's exact test), Q value = 1

Table S654. Gene #54: 'ARID2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ARID2 MUTATED	2	5	2	2
ARID2 WILD-TYPE	151	218	86	159

'ARID2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S655. Gene #54: 'ARID2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ARID2 MUTATED	2	2	3	1
ARID2 WILD-TYPE	183	153	135	94

'ARID2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S656. Gene #54: 'ARID2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ARID2 MUTATED	4	3	1
ARID2 WILD-TYPE	201	217	147

'ARID2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S657. Gene #54: 'ARID2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
ARID2 MUTATED	4	4	4
ARID2 WILD-TYPE	234	187	224

'ARID2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.132 (Fisher's exact test), Q value = 0.69

Table S658. Gene #54: 'ARID2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
ARID2 MUTATED	1	6	5
ARID2 WILD-TYPE	195	185	265

'ARID2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S659. Gene #54: 'ARID2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
ARID2 MUTATED	2	4	1	3
ARID2 WILD-TYPE	138	103	82	179

'ARID2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.344 (Fisher's exact test), Q value = 0.99

Table S660. Gene #54: 'ARID2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
ARID2 MUTATED	3	3	4
ARID2 WILD-TYPE	220	183	99

'ARID2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.835 (Fisher's exact test), Q value = 1

Table S661. Gene #54: 'ARID2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
ARID2 MUTATED	2	3	1	4
ARID2 WILD-TYPE	125	116	105	152

'ARID2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S662. Gene #54: 'ARID2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
ARID2 MUTATED	1	1	3	1	1	3
ARID2 WILD-TYPE	98	76	117	56	62	89

'KRTAP5-3 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S663. Gene #55: 'KRTAP5-3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
KRTAP5-3 MUTATED	2	2	0
KRTAP5-3 WILD-TYPE	290	430	62

'KRTAP5-3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.354 (Fisher's exact test), Q value = 1

Table S664. Gene #55: 'KRTAP5-3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
KRTAP5-3 MUTATED	2	1	1	0
KRTAP5-3 WILD-TYPE	151	222	87	161

'KRTAP5-3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.267 (Fisher's exact test), Q value = 0.91

Table S665. Gene #55: 'KRTAP5-3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
KRTAP5-3 MUTATED	1	0	1	2
KRTAP5-3 WILD-TYPE	184	155	137	93

'KRTAP5-3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S666. Gene #55: 'KRTAP5-3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
KRTAP5-3 MUTATED	2	1	1
KRTAP5-3 WILD-TYPE	203	219	147

'KRTAP5-3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.396 (Fisher's exact test), Q value = 1

Table S667. Gene #55: 'KRTAP5-3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
KRTAP5-3 MUTATED	3	0	1
KRTAP5-3 WILD-TYPE	235	191	227

'KRTAP5-3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.103 (Fisher's exact test), Q value = 0.61

Table S668. Gene #55: 'KRTAP5-3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
KRTAP5-3 MUTATED	3	1	0
KRTAP5-3 WILD-TYPE	193	190	270

'KRTAP5-3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0507 (Fisher's exact test), Q value = 0.41

Table S669. Gene #55: 'KRTAP5-3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
KRTAP5-3 MUTATED	3	0	0	0
KRTAP5-3 WILD-TYPE	137	107	83	182

'KRTAP5-3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.427 (Fisher's exact test), Q value = 1

Table S670. Gene #55: 'KRTAP5-3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
KRTAP5-3 MUTATED	2	0	1
KRTAP5-3 WILD-TYPE	221	186	102

'SRPX MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S671. Gene #56: 'SRPX MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SRPX MUTATED	2	2	0
SRPX WILD-TYPE	290	430	62

'SRPX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 0.86

Table S672. Gene #56: 'SRPX MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SRPX MUTATED	2	0	0	2
SRPX WILD-TYPE	151	223	88	159

'SRPX MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S673. Gene #56: 'SRPX MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
SRPX MUTATED	2	0	2	0
SRPX WILD-TYPE	183	155	136	95

'SRPX MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S674. Gene #56: 'SRPX MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
SRPX MUTATED	2	2	0
SRPX WILD-TYPE	203	218	148

'SRPX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.56 (Fisher's exact test), Q value = 1

Table S675. Gene #56: 'SRPX MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SRPX MUTATED	2	0	2
SRPX WILD-TYPE	236	191	226

'SRPX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.569 (Fisher's exact test), Q value = 1

Table S676. Gene #56: 'SRPX MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SRPX MUTATED	2	0	2
SRPX WILD-TYPE	194	191	268

'SRPX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.338 (Fisher's exact test), Q value = 0.98

Table S677. Gene #56: 'SRPX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
SRPX MUTATED	2	1	1	0
SRPX WILD-TYPE	138	106	82	182

'SRPX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.195 (Fisher's exact test), Q value = 0.83

Table S678. Gene #56: 'SRPX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
SRPX MUTATED	2	0	2
SRPX WILD-TYPE	221	186	101

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S679. Gene #56: 'SRPX MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
SRPX MUTATED	2	1	1	0
SRPX WILD-TYPE	125	118	105	156

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00856 (Fisher's exact test), Q value = 0.13

Table S680. Gene #56: 'SRPX MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
SRPX MUTATED	0	0	0	2	2	0
SRPX WILD-TYPE	99	77	120	55	61	92

Figure S183. Get High-res Image Gene #56: 'SRPX MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'WRN MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S681. Gene #57: 'WRN MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
WRN MUTATED	2	4	0
WRN WILD-TYPE	290	428	62

'WRN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0464 (Fisher's exact test), Q value = 0.4

Table S682. Gene #57: 'WRN MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
WRN MUTATED	1	0	0	4
WRN WILD-TYPE	152	223	88	157

Figure S184. Get High-res Image Gene #57: 'WRN MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'WRN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S683. Gene #57: 'WRN MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
WRN MUTATED	2	2	1	0
WRN WILD-TYPE	183	153	137	95

'WRN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S684. Gene #57: 'WRN MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
WRN MUTATED	2	1	2
WRN WILD-TYPE	203	219	146

'WRN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S685. Gene #57: 'WRN MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
WRN MUTATED	2	2	2
WRN WILD-TYPE	236	189	226

'WRN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.518 (Fisher's exact test), Q value = 1

Table S686. Gene #57: 'WRN MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
WRN MUTATED	1	1	4
WRN WILD-TYPE	195	190	266

'WRN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0576 (Fisher's exact test), Q value = 0.44

Table S687. Gene #57: 'WRN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
WRN MUTATED	0	1	3	1
WRN WILD-TYPE	140	106	80	181

'WRN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S688. Gene #57: 'WRN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
WRN MUTATED	2	2	1
WRN WILD-TYPE	221	184	102

'WRN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0112 (Fisher's exact test), Q value = 0.16

Table S689. Gene #57: 'WRN MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
WRN MUTATED	0	0	4	1
WRN WILD-TYPE	127	119	102	155

Figure S185. Get High-res Image Gene #57: 'WRN MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'WRN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00471 (Fisher's exact test), Q value = 0.089

Table S690. Gene #57: 'WRN MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
WRN MUTATED	0	0	0	3	0	2
WRN WILD-TYPE	99	77	120	54	63	90

Figure S186. Get High-res Image Gene #57: 'WRN MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'NEU2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.411 (Fisher's exact test), Q value = 1

Table S691. Gene #58: 'NEU2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
NEU2 MUTATED	1	0	0	2
NEU2 WILD-TYPE	77	41	64	55

'NEU2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S692. Gene #58: 'NEU2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
NEU2 MUTATED	0	1	0	2
NEU2 WILD-TYPE	63	49	48	77

'NEU2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S693. Gene #58: 'NEU2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
NEU2 MUTATED	1	1	1	0
NEU2 WILD-TYPE	69	97	43	63

'NEU2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S694. Gene #58: 'NEU2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
NEU2 MUTATED	2	0	1
NEU2 WILD-TYPE	136	61	75

'NEU2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S695. Gene #58: 'NEU2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
NEU2 MUTATED	4	4	1
NEU2 WILD-TYPE	288	428	61

'NEU2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.898 (Fisher's exact test), Q value = 1

Table S696. Gene #58: 'NEU2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
NEU2 MUTATED	1	3	1	1
NEU2 WILD-TYPE	152	220	87	160

'NEU2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S697. Gene #58: 'NEU2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
NEU2 MUTATED	2	2	1	2
NEU2 WILD-TYPE	183	153	137	93

'NEU2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.497 (Fisher's exact test), Q value = 1

Table S698. Gene #58: 'NEU2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
NEU2 MUTATED	1	4	2
NEU2 WILD-TYPE	204	216	146

'NEU2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.607 (Fisher's exact test), Q value = 1

Table S699. Gene #58: 'NEU2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
NEU2 MUTATED	4	1	3
NEU2 WILD-TYPE	234	190	225

'NEU2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.228 (Fisher's exact test), Q value = 0.89

Table S700. Gene #58: 'NEU2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
NEU2 MUTATED	3	4	1
NEU2 WILD-TYPE	193	187	269

'NEU2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.256 (Fisher's exact test), Q value = 0.91

Table S701. Gene #58: 'NEU2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
NEU2 MUTATED	0	2	2	2
NEU2 WILD-TYPE	140	105	81	180

'NEU2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.758 (Fisher's exact test), Q value = 1

Table S702. Gene #58: 'NEU2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
NEU2 MUTATED	2	2	2
NEU2 WILD-TYPE	221	184	101

'NEU2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S703. Gene #58: 'NEU2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
NEU2 MUTATED	1	0	2	3
NEU2 WILD-TYPE	126	119	104	153

'NEU2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 0.9

Table S704. Gene #58: 'NEU2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
NEU2 MUTATED	0	0	2	1	0	3
NEU2 WILD-TYPE	99	77	118	56	63	89

'TMEM216 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.436 (Fisher's exact test), Q value = 1

Table S705. Gene #59: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TMEM216 MUTATED	0	3	0
TMEM216 WILD-TYPE	292	429	62

'TMEM216 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.863 (Fisher's exact test), Q value = 1

Table S706. Gene #59: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TMEM216 MUTATED	0	2	0	1
TMEM216 WILD-TYPE	153	221	88	160

'TMEM216 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.872 (Fisher's exact test), Q value = 1

Table S707. Gene #59: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TMEM216 MUTATED	1	1	0	1
TMEM216 WILD-TYPE	184	154	138	94

'TMEM216 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.19 (Fisher's exact test), Q value = 0.83

Table S708. Gene #59: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TMEM216 MUTATED	1	0	2
TMEM216 WILD-TYPE	204	220	146

'TMEM216 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.201 (Fisher's exact test), Q value = 0.84

Table S709. Gene #59: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
TMEM216 MUTATED	0	2	1
TMEM216 WILD-TYPE	238	189	227

'TMEM216 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S710. Gene #59: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
TMEM216 MUTATED	0	1	2
TMEM216 WILD-TYPE	196	190	268

'TMEM216 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S711. Gene #59: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
TMEM216 MUTATED	0	1	1	1
TMEM216 WILD-TYPE	140	106	82	181

'TMEM216 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S712. Gene #59: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
TMEM216 MUTATED	1	2	0
TMEM216 WILD-TYPE	222	184	103

'TMEM216 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S713. Gene #59: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
TMEM216 MUTATED	0	2	0	1
TMEM216 WILD-TYPE	127	117	106	155

'TMEM216 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S714. Gene #59: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
TMEM216 MUTATED	0	1	1	0	0	1
TMEM216 WILD-TYPE	99	76	119	57	63	91

'KTELC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.83

Table S715. Gene #60: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
KTELC1 MUTATED	0	5	0
KTELC1 WILD-TYPE	292	427	62

'KTELC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.317 (Fisher's exact test), Q value = 0.95

Table S716. Gene #60: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
KTELC1 MUTATED	0	4	0	1
KTELC1 WILD-TYPE	153	219	88	160

'KTELC1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.469 (Fisher's exact test), Q value = 1

Table S717. Gene #60: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
KTELC1 MUTATED	3	1	0	0
KTELC1 WILD-TYPE	182	154	138	95

'KTELC1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.376 (Fisher's exact test), Q value = 1

Table S718. Gene #60: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
KTELC1 MUTATED	3	1	0
KTELC1 WILD-TYPE	202	219	148

'KTELC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.539 (Fisher's exact test), Q value = 1

Table S719. Gene #60: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
KTELC1 MUTATED	1	1	3
KTELC1 WILD-TYPE	237	190	225

'KTELC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.193 (Fisher's exact test), Q value = 0.83

Table S720. Gene #60: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
KTELC1 MUTATED	0	3	2
KTELC1 WILD-TYPE	196	188	268

'KTELC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.117 (Fisher's exact test), Q value = 0.64

Table S721. Gene #60: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
KTELC1 MUTATED	0	3	1	1
KTELC1 WILD-TYPE	140	104	82	181

'KTELC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0067 (Fisher's exact test), Q value = 0.11

Table S722. Gene #60: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
KTELC1 MUTATED	1	0	4
KTELC1 WILD-TYPE	222	186	99

Figure S187. Get High-res Image Gene #60: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'KTELC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.93 (Fisher's exact test), Q value = 1

Table S723. Gene #60: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
KTELC1 MUTATED	2	1	1	1
KTELC1 WILD-TYPE	125	118	105	155

'KTELC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.502 (Fisher's exact test), Q value = 1

Table S724. Gene #60: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
KTELC1 MUTATED	1	1	0	1	0	2
KTELC1 WILD-TYPE	98	76	120	56	63	90

'ZNF41 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.357 (Fisher's exact test), Q value = 1

Table S725. Gene #61: 'ZNF41 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ZNF41 MUTATED	5	3	0
ZNF41 WILD-TYPE	287	429	62

'ZNF41 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S726. Gene #61: 'ZNF41 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ZNF41 MUTATED	3	2	1	1
ZNF41 WILD-TYPE	150	221	87	160

'ZNF41 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S727. Gene #61: 'ZNF41 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ZNF41 MUTATED	1	1	2	1
ZNF41 WILD-TYPE	184	154	136	94

'ZNF41 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S728. Gene #61: 'ZNF41 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ZNF41 MUTATED	2	2	1
ZNF41 WILD-TYPE	203	218	147

'ZNF41 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S729. Gene #61: 'ZNF41 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
ZNF41 MUTATED	2	2	2
ZNF41 WILD-TYPE	236	189	226

'ZNF41 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S730. Gene #61: 'ZNF41 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
ZNF41 MUTATED	1	2	3
ZNF41 WILD-TYPE	195	189	267

'ZNF41 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.803 (Fisher's exact test), Q value = 1

Table S731. Gene #61: 'ZNF41 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
ZNF41 MUTATED	2	2	0	2
ZNF41 WILD-TYPE	138	105	83	180

'ZNF41 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.755 (Fisher's exact test), Q value = 1

Table S732. Gene #61: 'ZNF41 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
ZNF41 MUTATED	2	2	2
ZNF41 WILD-TYPE	221	184	101

'ZNF41 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 0.64

Table S733. Gene #61: 'ZNF41 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
ZNF41 MUTATED	0	3	0	3
ZNF41 WILD-TYPE	127	116	106	153

'ZNF41 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S734. Gene #61: 'ZNF41 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
ZNF41 MUTATED	0	2	2	0	1	1
ZNF41 WILD-TYPE	99	75	118	57	62	91

'SOX4 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S735. Gene #62: 'SOX4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SOX4 MUTATED	2	4	0
SOX4 WILD-TYPE	290	428	62

'SOX4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.272 (Fisher's exact test), Q value = 0.91

Table S736. Gene #62: 'SOX4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SOX4 MUTATED	2	1	0	4
SOX4 WILD-TYPE	151	222	88	157

'SOX4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.914 (Fisher's exact test), Q value = 1

Table S737. Gene #62: 'SOX4 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
SOX4 MUTATED	2	1	1	0
SOX4 WILD-TYPE	183	154	137	95

'SOX4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S738. Gene #62: 'SOX4 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
SOX4 MUTATED	1	3	0
SOX4 WILD-TYPE	204	217	148

'SOX4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.187 (Fisher's exact test), Q value = 0.83

Table S739. Gene #62: 'SOX4 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SOX4 MUTATED	3	0	4
SOX4 WILD-TYPE	235	191	224

'SOX4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.652 (Fisher's exact test), Q value = 1

Table S740. Gene #62: 'SOX4 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SOX4 MUTATED	1	2	4
SOX4 WILD-TYPE	195	189	266

'SOX4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00641 (Fisher's exact test), Q value = 0.11

Table S741. Gene #62: 'SOX4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
SOX4 MUTATED	1	1	4	0
SOX4 WILD-TYPE	139	106	79	182

Figure S188. Get High-res Image Gene #62: 'SOX4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'SOX4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.12 (Fisher's exact test), Q value = 0.65

Table S742. Gene #62: 'SOX4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
SOX4 MUTATED	4	0	2
SOX4 WILD-TYPE	219	186	101

'SOX4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0523 (Fisher's exact test), Q value = 0.41

Table S743. Gene #62: 'SOX4 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
SOX4 MUTATED	0	1	4	1
SOX4 WILD-TYPE	127	118	102	155

'SOX4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0303 (Fisher's exact test), Q value = 0.3

Table S744. Gene #62: 'SOX4 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
SOX4 MUTATED	0	1	0	3	1	1
SOX4 WILD-TYPE	99	76	120	54	62	91

Figure S189. Get High-res Image Gene #62: 'SOX4 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'SERPING1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S745. Gene #63: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SERPING1 MUTATED	2	2	0
SERPING1 WILD-TYPE	290	430	62

'SERPING1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S746. Gene #63: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SERPING1 MUTATED	1	1	1	1
SERPING1 WILD-TYPE	152	222	87	160

'SERPING1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S747. Gene #63: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
SERPING1 MUTATED	2	1	0	1
SERPING1 WILD-TYPE	183	154	138	94

'SERPING1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.139 (Fisher's exact test), Q value = 0.7

Table S748. Gene #63: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
SERPING1 MUTATED	3	0	1
SERPING1 WILD-TYPE	202	220	147

'SERPING1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.202 (Fisher's exact test), Q value = 0.84

Table S749. Gene #63: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SERPING1 MUTATED	0	2	1
SERPING1 WILD-TYPE	238	189	227

'SERPING1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.636 (Fisher's exact test), Q value = 1

Table S750. Gene #63: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SERPING1 MUTATED	0	1	2
SERPING1 WILD-TYPE	196	190	268

'SERPING1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.596 (Fisher's exact test), Q value = 1

Table S751. Gene #63: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
SERPING1 MUTATED	0	1	0	2
SERPING1 WILD-TYPE	140	106	83	180

'SERPING1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S752. Gene #63: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
SERPING1 MUTATED	1	2	0
SERPING1 WILD-TYPE	222	184	103

'SERPING1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.632 (Fisher's exact test), Q value = 1

Table S753. Gene #63: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
SERPING1 MUTATED	1	0	0	2
SERPING1 WILD-TYPE	126	119	106	154

'SERPING1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S754. Gene #63: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
SERPING1 MUTATED	1	0	2	0	0	0
SERPING1 WILD-TYPE	98	77	118	57	63	92

'RASGRF2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.418 (Fisher's exact test), Q value = 1

Table S755. Gene #64: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
RASGRF2 MUTATED	4	2	0
RASGRF2 WILD-TYPE	288	430	62

'RASGRF2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.183 (Fisher's exact test), Q value = 0.83

Table S756. Gene #64: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
RASGRF2 MUTATED	4	1	0	1
RASGRF2 WILD-TYPE	149	222	88	160

'RASGRF2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.917 (Fisher's exact test), Q value = 1

Table S757. Gene #64: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
RASGRF2 MUTATED	2	1	1	0
RASGRF2 WILD-TYPE	183	154	137	95

'RASGRF2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S758. Gene #64: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
RASGRF2 MUTATED	1	2	1
RASGRF2 WILD-TYPE	204	218	147

'RASGRF2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S759. Gene #64: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
RASGRF2 MUTATED	4	1	1
RASGRF2 WILD-TYPE	234	190	227

'RASGRF2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.67 (Fisher's exact test), Q value = 1

Table S760. Gene #64: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
RASGRF2 MUTATED	3	1	2
RASGRF2 WILD-TYPE	193	190	268

'RASGRF2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.069 (Fisher's exact test), Q value = 0.48

Table S761. Gene #64: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
RASGRF2 MUTATED	0	3	0	1
RASGRF2 WILD-TYPE	140	104	83	181

'RASGRF2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0134 (Fisher's exact test), Q value = 0.18

Table S762. Gene #64: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
RASGRF2 MUTATED	0	1	3
RASGRF2 WILD-TYPE	223	185	100

Figure S190. Get High-res Image Gene #64: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'RASGRF2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S763. Gene #64: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
RASGRF2 MUTATED	0	1	2	1
RASGRF2 WILD-TYPE	127	118	104	155

'RASGRF2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0413 (Fisher's exact test), Q value = 0.37

Table S764. Gene #64: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
RASGRF2 MUTATED	0	0	0	0	1	3
RASGRF2 WILD-TYPE	99	77	120	57	62	89

Figure S191. Get High-res Image Gene #64: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'FAM83D MUTATION STATUS' versus 'CN_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S765. Gene #65: 'FAM83D MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
FAM83D MUTATED	4	2	0
FAM83D WILD-TYPE	288	430	62

'FAM83D MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.183 (Fisher's exact test), Q value = 0.83

Table S766. Gene #65: 'FAM83D MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
FAM83D MUTATED	4	1	0	1
FAM83D WILD-TYPE	149	222	88	160

'FAM83D MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.599 (Fisher's exact test), Q value = 1

Table S767. Gene #65: 'FAM83D MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
FAM83D MUTATED	1	2	0	1
FAM83D WILD-TYPE	184	153	138	94

'FAM83D MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.68 (Fisher's exact test), Q value = 1

Table S768. Gene #65: 'FAM83D MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
FAM83D MUTATED	2	2	0
FAM83D WILD-TYPE	203	218	148

'FAM83D MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S769. Gene #65: 'FAM83D MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
FAM83D MUTATED	3	1	1
FAM83D WILD-TYPE	235	190	227

'FAM83D MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.62 (Fisher's exact test), Q value = 1

Table S770. Gene #65: 'FAM83D MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
FAM83D MUTATED	2	2	1
FAM83D WILD-TYPE	194	189	269

'FAM83D MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 1

Table S771. Gene #65: 'FAM83D MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
FAM83D MUTATED	1	2	0	1
FAM83D WILD-TYPE	139	105	83	181

'FAM83D MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0138 (Fisher's exact test), Q value = 0.18

Table S772. Gene #65: 'FAM83D MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
FAM83D MUTATED	0	1	3
FAM83D WILD-TYPE	223	185	100

Figure S192. Get High-res Image Gene #65: 'FAM83D MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'FAM83D MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.783 (Fisher's exact test), Q value = 1

Table S773. Gene #65: 'FAM83D MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
FAM83D MUTATED	0	1	1	2
FAM83D WILD-TYPE	127	118	105	154

'FAM83D MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0415 (Fisher's exact test), Q value = 0.37

Table S774. Gene #65: 'FAM83D MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
FAM83D MUTATED	0	0	0	0	1	3
FAM83D WILD-TYPE	99	77	120	57	62	89

Figure S193. Get High-res Image Gene #65: 'FAM83D MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ZNF512B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.771 (Fisher's exact test), Q value = 1

Table S775. Gene #66: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ZNF512B MUTATED	1	4	0
ZNF512B WILD-TYPE	291	428	62

'ZNF512B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S776. Gene #66: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ZNF512B MUTATED	1	3	0	1
ZNF512B WILD-TYPE	152	220	88	160

'ZNF512B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.633 (Fisher's exact test), Q value = 1

Table S777. Gene #66: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ZNF512B MUTATED	2	2	0	1
ZNF512B WILD-TYPE	183	153	138	94

'ZNF512B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S778. Gene #66: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ZNF512B MUTATED	2	2	1
ZNF512B WILD-TYPE	203	218	147

'ZNF512B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.745 (Fisher's exact test), Q value = 1

Table S779. Gene #66: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
ZNF512B MUTATED	1	2	2
ZNF512B WILD-TYPE	237	189	226

'ZNF512B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.338 (Fisher's exact test), Q value = 0.98

Table S780. Gene #66: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
ZNF512B MUTATED	0	2	3
ZNF512B WILD-TYPE	196	189	267

'ZNF512B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S781. Gene #66: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
ZNF512B MUTATED	1	1	1	2
ZNF512B WILD-TYPE	139	106	82	180

'ZNF512B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S782. Gene #66: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
ZNF512B MUTATED	2	2	1
ZNF512B WILD-TYPE	221	184	102

'ZNF512B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S783. Gene #66: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
ZNF512B MUTATED	0	1	1	3
ZNF512B WILD-TYPE	127	118	105	153

'ZNF512B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S784. Gene #66: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
ZNF512B MUTATED	1	0	2	0	0	2
ZNF512B WILD-TYPE	98	77	118	57	63	90

'ATF7IP2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.916 (Fisher's exact test), Q value = 1

Table S785. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
ATF7IP2 MUTATED	2	0	1	1
ATF7IP2 WILD-TYPE	76	41	63	56

'ATF7IP2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S786. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
ATF7IP2 MUTATED	1	1	1	1
ATF7IP2 WILD-TYPE	62	49	47	78

'ATF7IP2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.326 (Fisher's exact test), Q value = 0.97

Table S787. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
ATF7IP2 MUTATED	1	1	0	3
ATF7IP2 WILD-TYPE	69	97	44	60

'ATF7IP2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.105 (Fisher's exact test), Q value = 0.61

Table S788. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
ATF7IP2 MUTATED	1	3	1
ATF7IP2 WILD-TYPE	137	58	75

'ATF7IP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0389 (Fisher's exact test), Q value = 0.36

Table S789. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ATF7IP2 MUTATED	6	1	1
ATF7IP2 WILD-TYPE	286	431	61

Figure S194. Get High-res Image Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'ATF7IP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.353 (Fisher's exact test), Q value = 1

Table S790. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ATF7IP2 MUTATED	2	1	1	0
ATF7IP2 WILD-TYPE	151	222	87	161

'ATF7IP2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S791. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ATF7IP2 MUTATED	2	2	0	1
ATF7IP2 WILD-TYPE	183	153	138	94

'ATF7IP2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S792. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ATF7IP2 MUTATED	2	2	1
ATF7IP2 WILD-TYPE	203	218	147

'ATF7IP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0384 (Fisher's exact test), Q value = 0.35

Table S793. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
ATF7IP2 MUTATED	4	0	0
ATF7IP2 WILD-TYPE	234	191	228

Figure S195. Get High-res Image Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'ATF7IP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.102 (Fisher's exact test), Q value = 0.6

Table S794. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
ATF7IP2 MUTATED	3	1	0
ATF7IP2 WILD-TYPE	193	190	270

'ATF7IP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S795. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
ATF7IP2 MUTATED	1	1	0	1
ATF7IP2 WILD-TYPE	139	106	83	181

'ATF7IP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00793 (Fisher's exact test), Q value = 0.13

Table S796. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
ATF7IP2 MUTATED	0	0	3
ATF7IP2 WILD-TYPE	223	186	100

Figure S196. Get High-res Image Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'ATF7IP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.021 (Fisher's exact test), Q value = 0.24

Table S797. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
ATF7IP2 MUTATED	0	3	0	0
ATF7IP2 WILD-TYPE	127	116	106	156

Figure S197. Get High-res Image Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'ATF7IP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.097 (Fisher's exact test), Q value = 0.58

Table S798. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
ATF7IP2 MUTATED	1	0	0	0	2	0
ATF7IP2 WILD-TYPE	98	77	120	57	61	92

'TPX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S799. Gene #68: 'TPX2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TPX2 MUTATED	3	4	0
TPX2 WILD-TYPE	289	428	62

'TPX2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S800. Gene #68: 'TPX2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TPX2 MUTATED	3	3	0	1
TPX2 WILD-TYPE	150	220	88	160

'TPX2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S801. Gene #68: 'TPX2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TPX2 MUTATED	1	2	1	0
TPX2 WILD-TYPE	184	153	137	95

'TPX2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S802. Gene #68: 'TPX2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TPX2 MUTATED	1	2	1
TPX2 WILD-TYPE	204	218	147

'TPX2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S803. Gene #68: 'TPX2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
TPX2 MUTATED	2	2	2
TPX2 WILD-TYPE	236	189	226

'TPX2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S804. Gene #68: 'TPX2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
TPX2 MUTATED	1	3	2
TPX2 WILD-TYPE	195	188	268

'TPX2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S805. Gene #68: 'TPX2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
TPX2 MUTATED	0	1	1	3
TPX2 WILD-TYPE	140	106	82	179

'TPX2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0696 (Fisher's exact test), Q value = 0.48

Table S806. Gene #68: 'TPX2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
TPX2 MUTATED	0	4	1
TPX2 WILD-TYPE	223	182	102

'TPX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0947 (Fisher's exact test), Q value = 0.57

Table S807. Gene #68: 'TPX2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
TPX2 MUTATED	0	0	1	4
TPX2 WILD-TYPE	127	119	105	152

'TPX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S808. Gene #68: 'TPX2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
TPX2 MUTATED	0	0	2	1	0	2
TPX2 WILD-TYPE	99	77	118	56	63	90

'ZBTB20 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00101 (Fisher's exact test), Q value = 0.024

Table S809. Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ZBTB20 MUTATED	1	20	1
ZBTB20 WILD-TYPE	291	412	61

Figure S198. Get High-res Image Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'ZBTB20 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00015 (Fisher's exact test), Q value = 0.0044

Table S810. Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ZBTB20 MUTATED	2	3	1	15
ZBTB20 WILD-TYPE	151	220	87	146

Figure S199. Get High-res Image Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'ZBTB20 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.655 (Fisher's exact test), Q value = 1

Table S811. Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ZBTB20 MUTATED	5	6	2	3
ZBTB20 WILD-TYPE	180	149	136	92

'ZBTB20 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0938 (Fisher's exact test), Q value = 0.57

Table S812. Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ZBTB20 MUTATED	3	5	8
ZBTB20 WILD-TYPE	202	215	140

'ZBTB20 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00015 (Fisher's exact test), Q value = 0.0044

Table S813. Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
ZBTB20 MUTATED	3	16	3
ZBTB20 WILD-TYPE	235	175	225

Figure S200. Get High-res Image Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'ZBTB20 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 3e-05 (Fisher's exact test), Q value = 0.0011

Table S814. Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
ZBTB20 MUTATED	0	3	19
ZBTB20 WILD-TYPE	196	188	251

Figure S201. Get High-res Image Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'ZBTB20 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.143 (Fisher's exact test), Q value = 0.71

Table S815. Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
ZBTB20 MUTATED	3	2	4	12
ZBTB20 WILD-TYPE	137	105	79	170

'ZBTB20 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.021 (Fisher's exact test), Q value = 0.24

Table S816. Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
ZBTB20 MUTATED	5	14	2
ZBTB20 WILD-TYPE	218	172	101

Figure S202. Get High-res Image Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'ZBTB20 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0138 (Fisher's exact test), Q value = 0.18

Table S817. Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
ZBTB20 MUTATED	3	1	4	13
ZBTB20 WILD-TYPE	124	118	102	143

Figure S203. Get High-res Image Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'ZBTB20 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.145 (Fisher's exact test), Q value = 0.71

Table S818. Gene #69: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
ZBTB20 MUTATED	1	4	9	1	1	5
ZBTB20 WILD-TYPE	98	73	111	56	62	87

'C10ORF76 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.502 (Fisher's exact test), Q value = 1

Table S819. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
C10ORF76 MUTATED	3	1	0
C10ORF76 WILD-TYPE	289	431	62

'C10ORF76 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0645 (Fisher's exact test), Q value = 0.46

Table S820. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
C10ORF76 MUTATED	3	0	0	1
C10ORF76 WILD-TYPE	150	223	88	160

'C10ORF76 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.211 (Fisher's exact test), Q value = 0.85

Table S821. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
C10ORF76 MUTATED	3	1	0
C10ORF76 WILD-TYPE	235	190	228

'C10ORF76 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S822. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
C10ORF76 MUTATED	2	1	1
C10ORF76 WILD-TYPE	194	190	269

'C10ORF76 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.283 (Fisher's exact test), Q value = 0.93

Table S823. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
C10ORF76 MUTATED	0	2	0	1
C10ORF76 WILD-TYPE	140	105	83	181

'C10ORF76 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.053 (Fisher's exact test), Q value = 0.42

Table S824. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
C10ORF76 MUTATED	0	1	2
C10ORF76 WILD-TYPE	223	185	101

'C10ORF76 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.561 (Fisher's exact test), Q value = 1

Table S825. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
C10ORF76 MUTATED	0	1	0	2
C10ORF76 WILD-TYPE	127	118	106	154

'C10ORF76 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S826. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
C10ORF76 MUTATED	0	0	1	0	1	1
C10ORF76 WILD-TYPE	99	77	119	57	62	91

'TRPV6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.575 (Fisher's exact test), Q value = 1

Table S827. Gene #71: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
TRPV6 MUTATED	1	2	1	2
TRPV6 WILD-TYPE	77	39	63	55

'TRPV6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.228 (Fisher's exact test), Q value = 0.89

Table S828. Gene #71: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
TRPV6 MUTATED	0	3	1	2
TRPV6 WILD-TYPE	63	47	47	77

'TRPV6 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.27 (Fisher's exact test), Q value = 0.91

Table S829. Gene #71: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
TRPV6 MUTATED	0	4	2	1
TRPV6 WILD-TYPE	70	94	42	62

'TRPV6 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S830. Gene #71: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TRPV6 MUTATED	4	1	2
TRPV6 WILD-TYPE	134	60	74

'TRPV6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.223 (Fisher's exact test), Q value = 0.88

Table S831. Gene #71: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TRPV6 MUTATED	7	4	1
TRPV6 WILD-TYPE	285	428	61

'TRPV6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.482 (Fisher's exact test), Q value = 1

Table S832. Gene #71: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TRPV6 MUTATED	3	1	1	2
TRPV6 WILD-TYPE	150	222	87	159

'TRPV6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S833. Gene #71: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TRPV6 MUTATED	3	3	1	1
TRPV6 WILD-TYPE	182	152	137	94

'TRPV6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S834. Gene #71: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TRPV6 MUTATED	1	4	3
TRPV6 WILD-TYPE	204	216	145

'TRPV6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0998 (Fisher's exact test), Q value = 0.6

Table S835. Gene #71: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
TRPV6 MUTATED	7	3	1
TRPV6 WILD-TYPE	231	188	227

'TRPV6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S836. Gene #71: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
TRPV6 MUTATED	5	3	3
TRPV6 WILD-TYPE	191	188	267

'TRPV6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S837. Gene #71: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
TRPV6 MUTATED	1	2	0	3
TRPV6 WILD-TYPE	139	105	83	179

'TRPV6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.504 (Fisher's exact test), Q value = 1

Table S838. Gene #71: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
TRPV6 MUTATED	3	1	2
TRPV6 WILD-TYPE	220	185	101

'TRPV6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S839. Gene #71: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
TRPV6 MUTATED	1	2	0	3
TRPV6 WILD-TYPE	126	117	106	153

'TRPV6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.939 (Fisher's exact test), Q value = 1

Table S840. Gene #71: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
TRPV6 MUTATED	1	1	1	0	1	2
TRPV6 WILD-TYPE	98	76	119	57	62	90

'PDHA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.333 (Fisher's exact test), Q value = 0.98

Table S841. Gene #72: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PDHA1 MUTATED	1	4	1
PDHA1 WILD-TYPE	291	428	61

'PDHA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S842. Gene #72: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
PDHA1 MUTATED	1	1	0	3
PDHA1 WILD-TYPE	152	222	88	158

'PDHA1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S843. Gene #72: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PDHA1 MUTATED	3	1	1	1
PDHA1 WILD-TYPE	182	154	137	94

'PDHA1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.299 (Fisher's exact test), Q value = 0.94

Table S844. Gene #72: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PDHA1 MUTATED	4	1	1
PDHA1 WILD-TYPE	201	219	147

'PDHA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S845. Gene #72: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
PDHA1 MUTATED	2	1	3
PDHA1 WILD-TYPE	236	190	225

'PDHA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.884 (Fisher's exact test), Q value = 1

Table S846. Gene #72: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
PDHA1 MUTATED	2	1	3
PDHA1 WILD-TYPE	194	190	267

'PDHA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.929 (Fisher's exact test), Q value = 1

Table S847. Gene #72: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
PDHA1 MUTATED	2	1	0	2
PDHA1 WILD-TYPE	138	106	83	180

'PDHA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.847 (Fisher's exact test), Q value = 1

Table S848. Gene #72: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
PDHA1 MUTATED	3	1	1
PDHA1 WILD-TYPE	220	185	102

'PDHA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.872 (Fisher's exact test), Q value = 1

Table S849. Gene #72: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
PDHA1 MUTATED	1	2	1	1
PDHA1 WILD-TYPE	126	117	105	155

'PDHA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0937 (Fisher's exact test), Q value = 0.57

Table S850. Gene #72: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
PDHA1 MUTATED	0	3	1	0	1	0
PDHA1 WILD-TYPE	99	74	119	57	62	92

'ZDHHC4 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 0.89

Table S851. Gene #73: 'ZDHHC4 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
ZDHHC4 MUTATED	0	3	0	0
ZDHHC4 WILD-TYPE	70	95	44	63

'ZDHHC4 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S852. Gene #73: 'ZDHHC4 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
ZDHHC4 MUTATED	2	0	1
ZDHHC4 WILD-TYPE	136	61	75

'ZDHHC4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0703 (Fisher's exact test), Q value = 0.48

Table S853. Gene #73: 'ZDHHC4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ZDHHC4 MUTATED	4	0	0
ZDHHC4 WILD-TYPE	288	432	62

'ZDHHC4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.009 (Fisher's exact test), Q value = 0.13

Table S854. Gene #73: 'ZDHHC4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ZDHHC4 MUTATED	4	0	0	0
ZDHHC4 WILD-TYPE	149	223	88	161

Figure S204. Get High-res Image Gene #73: 'ZDHHC4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'ZDHHC4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S855. Gene #73: 'ZDHHC4 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ZDHHC4 MUTATED	1	1	1	0
ZDHHC4 WILD-TYPE	184	154	137	95

'ZDHHC4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S856. Gene #73: 'ZDHHC4 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ZDHHC4 MUTATED	2	1	0
ZDHHC4 WILD-TYPE	203	219	148

'FAM123C MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0326 (Fisher's exact test), Q value = 0.31

Table S857. Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
FAM123C MUTATED	3	3	0	0
FAM123C WILD-TYPE	75	38	64	57

Figure S205. Get High-res Image Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'FAM123C MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.558 (Fisher's exact test), Q value = 1

Table S858. Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
FAM123C MUTATED	3	1	0	2
FAM123C WILD-TYPE	60	49	48	77

'FAM123C MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S859. Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
FAM123C MUTATED	2	3	0	1
FAM123C WILD-TYPE	68	95	44	62

'FAM123C MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.12 (Fisher's exact test), Q value = 0.65

Table S860. Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
FAM123C MUTATED	1	3	2
FAM123C WILD-TYPE	137	58	74

'FAM123C MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0262 (Fisher's exact test), Q value = 0.27

Table S861. Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
FAM123C MUTATED	7	2	2
FAM123C WILD-TYPE	285	430	60

Figure S206. Get High-res Image Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'FAM123C MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.233 (Fisher's exact test), Q value = 0.89

Table S862. Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
FAM123C MUTATED	2	2	2	0
FAM123C WILD-TYPE	151	221	86	161

'FAM123C MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.308 (Fisher's exact test), Q value = 0.94

Table S863. Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
FAM123C MUTATED	3	0	3	1
FAM123C WILD-TYPE	182	155	135	94

'FAM123C MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.273 (Fisher's exact test), Q value = 0.91

Table S864. Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
FAM123C MUTATED	4	3	0
FAM123C WILD-TYPE	201	217	148

'FAM123C MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 0.68

Table S865. Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
FAM123C MUTATED	5	0	3
FAM123C WILD-TYPE	233	191	225

'FAM123C MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.105 (Fisher's exact test), Q value = 0.61

Table S866. Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
FAM123C MUTATED	5	2	1
FAM123C WILD-TYPE	191	189	269

'FAM123C MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0815 (Fisher's exact test), Q value = 0.53

Table S867. Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
FAM123C MUTATED	3	0	1	0
FAM123C WILD-TYPE	137	107	82	182

'FAM123C MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.261 (Fisher's exact test), Q value = 0.91

Table S868. Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
FAM123C MUTATED	3	0	1
FAM123C WILD-TYPE	220	186	102

'FAM123C MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S869. Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
FAM123C MUTATED	1	2	1	0
FAM123C WILD-TYPE	126	117	105	156

'FAM123C MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.33 (Fisher's exact test), Q value = 0.97

Table S870. Gene #74: 'FAM123C MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
FAM123C MUTATED	2	1	0	0	1	0
FAM123C WILD-TYPE	97	76	120	57	62	92

'CPEB4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.833 (Fisher's exact test), Q value = 1

Table S871. Gene #75: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
CPEB4 MUTATED	2	5	0
CPEB4 WILD-TYPE	290	427	62

'CPEB4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S872. Gene #75: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
CPEB4 MUTATED	1	1	1	3
CPEB4 WILD-TYPE	152	222	87	158

'CPEB4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.36 (Fisher's exact test), Q value = 1

Table S873. Gene #75: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
CPEB4 MUTATED	3	1	0	2
CPEB4 WILD-TYPE	182	154	138	93

'CPEB4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.772 (Fisher's exact test), Q value = 1

Table S874. Gene #75: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
CPEB4 MUTATED	3	2	1
CPEB4 WILD-TYPE	202	218	147

'CPEB4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.798 (Fisher's exact test), Q value = 1

Table S875. Gene #75: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
CPEB4 MUTATED	2	3	2
CPEB4 WILD-TYPE	236	188	226

'CPEB4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.652 (Fisher's exact test), Q value = 1

Table S876. Gene #75: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
CPEB4 MUTATED	1	2	4
CPEB4 WILD-TYPE	195	189	266

'CPEB4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S877. Gene #75: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
CPEB4 MUTATED	1	1	2	2
CPEB4 WILD-TYPE	139	106	81	180

'CPEB4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S878. Gene #75: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
CPEB4 MUTATED	3	2	1
CPEB4 WILD-TYPE	220	184	102

'CPEB4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S879. Gene #75: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
CPEB4 MUTATED	0	1	2	3
CPEB4 WILD-TYPE	127	118	104	153

'CPEB4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.304 (Fisher's exact test), Q value = 0.94

Table S880. Gene #75: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
CPEB4 MUTATED	0	1	1	2	0	2
CPEB4 WILD-TYPE	99	76	119	55	63	90

'EEF1A1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.238 (Fisher's exact test), Q value = 0.89

Table S881. Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
EEF1A1 MUTATED	1	0	3	0
EEF1A1 WILD-TYPE	77	41	61	57

'EEF1A1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.192 (Fisher's exact test), Q value = 0.83

Table S882. Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
EEF1A1 MUTATED	0	0	2	2
EEF1A1 WILD-TYPE	63	50	46	77

'EEF1A1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.642 (Fisher's exact test), Q value = 1

Table S883. Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
EEF1A1 MUTATED	0	2	1	1
EEF1A1 WILD-TYPE	70	96	43	62

'EEF1A1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S884. Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
EEF1A1 MUTATED	1	1	2
EEF1A1 WILD-TYPE	137	60	74

'EEF1A1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.014 (Fisher's exact test), Q value = 0.18

Table S885. Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
EEF1A1 MUTATED	7	1	0
EEF1A1 WILD-TYPE	285	431	62

Figure S207. Get High-res Image Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'EEF1A1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.368 (Fisher's exact test), Q value = 1

Table S886. Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
EEF1A1 MUTATED	3	1	0	1
EEF1A1 WILD-TYPE	150	222	88	160

'EEF1A1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0521 (Fisher's exact test), Q value = 0.41

Table S887. Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
EEF1A1 MUTATED	4	0	0	0
EEF1A1 WILD-TYPE	181	155	138	95

'EEF1A1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.686 (Fisher's exact test), Q value = 1

Table S888. Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
EEF1A1 MUTATED	2	2	0
EEF1A1 WILD-TYPE	203	218	148

'EEF1A1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 0.9

Table S889. Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
EEF1A1 MUTATED	4	0	2
EEF1A1 WILD-TYPE	234	191	226

'EEF1A1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S890. Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
EEF1A1 MUTATED	3	2	1
EEF1A1 WILD-TYPE	193	189	269

'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0219 (Fisher's exact test), Q value = 0.24

Table S891. Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
EEF1A1 MUTATED	0	3	1	0
EEF1A1 WILD-TYPE	140	104	82	182

Figure S208. Get High-res Image Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.194 (Fisher's exact test), Q value = 0.83

Table S892. Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
EEF1A1 MUTATED	2	0	2
EEF1A1 WILD-TYPE	221	186	101

'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.676 (Fisher's exact test), Q value = 1

Table S893. Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
EEF1A1 MUTATED	1	2	0	1
EEF1A1 WILD-TYPE	126	117	106	155

'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.503 (Fisher's exact test), Q value = 1

Table S894. Gene #76: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
EEF1A1 MUTATED	1	0	0	1	1	1
EEF1A1 WILD-TYPE	98	77	120	56	62	91

'PROKR2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.497 (Fisher's exact test), Q value = 1

Table S895. Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
PROKR2 MUTATED	1	0	3	1
PROKR2 WILD-TYPE	77	41	61	56

'PROKR2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.727 (Fisher's exact test), Q value = 1

Table S896. Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PROKR2 MUTATED	1	1	2	1
PROKR2 WILD-TYPE	62	49	46	78

'PROKR2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S897. Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
PROKR2 MUTATED	0	2	1	2
PROKR2 WILD-TYPE	70	96	43	61

'PROKR2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.184 (Fisher's exact test), Q value = 0.83

Table S898. Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PROKR2 MUTATED	1	1	3
PROKR2 WILD-TYPE	137	60	73

'PROKR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0128 (Fisher's exact test), Q value = 0.18

Table S899. Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PROKR2 MUTATED	7	1	1
PROKR2 WILD-TYPE	285	431	61

Figure S209. Get High-res Image Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'PROKR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.241 (Fisher's exact test), Q value = 0.89

Table S900. Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
PROKR2 MUTATED	3	2	0	0
PROKR2 WILD-TYPE	150	221	88	161

'PROKR2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.252 (Fisher's exact test), Q value = 0.9

Table S901. Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PROKR2 MUTATED	0	1	2	0
PROKR2 WILD-TYPE	185	154	136	95

'PROKR2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S902. Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PROKR2 MUTATED	0	2	1
PROKR2 WILD-TYPE	205	218	147

'PROKR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.101 (Fisher's exact test), Q value = 0.6

Table S903. Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
PROKR2 MUTATED	6	1	1
PROKR2 WILD-TYPE	232	190	227

'PROKR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0368 (Fisher's exact test), Q value = 0.34

Table S904. Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
PROKR2 MUTATED	6	1	1
PROKR2 WILD-TYPE	190	190	269

Figure S210. Get High-res Image Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'PROKR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.237 (Fisher's exact test), Q value = 0.89

Table S905. Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
PROKR2 MUTATED	0	0	0	3
PROKR2 WILD-TYPE	140	107	83	179

'PROKR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S906. Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
PROKR2 MUTATED	1	1	1
PROKR2 WILD-TYPE	222	185	102

'PROKR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S907. Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
PROKR2 MUTATED	1	1	0	1
PROKR2 WILD-TYPE	126	118	106	155

'PROKR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S908. Gene #77: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
PROKR2 MUTATED	0	1	0	0	1	1
PROKR2 WILD-TYPE	99	76	120	57	62	91

'DNMT3A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0821 (Fisher's exact test), Q value = 0.53

Table S909. Gene #78: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
DNMT3A MUTATED	1	10	0
DNMT3A WILD-TYPE	291	422	62

'DNMT3A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.973 (Fisher's exact test), Q value = 1

Table S910. Gene #78: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
DNMT3A MUTATED	2	5	1	3
DNMT3A WILD-TYPE	151	218	87	158

'DNMT3A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S911. Gene #78: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
DNMT3A MUTATED	3	3	1	1
DNMT3A WILD-TYPE	182	152	137	94

'DNMT3A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.184 (Fisher's exact test), Q value = 0.83

Table S912. Gene #78: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
DNMT3A MUTATED	3	1	4
DNMT3A WILD-TYPE	202	219	144

'DNMT3A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.122 (Fisher's exact test), Q value = 0.66

Table S913. Gene #78: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
DNMT3A MUTATED	1	5	5
DNMT3A WILD-TYPE	237	186	223

'DNMT3A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.052 (Fisher's exact test), Q value = 0.41

Table S914. Gene #78: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
DNMT3A MUTATED	0	4	7
DNMT3A WILD-TYPE	196	187	263

'DNMT3A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 0.94

Table S915. Gene #78: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
DNMT3A MUTATED	1	2	1	7
DNMT3A WILD-TYPE	139	105	82	175

'DNMT3A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0314 (Fisher's exact test), Q value = 0.31

Table S916. Gene #78: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
DNMT3A MUTATED	1	6	4
DNMT3A WILD-TYPE	222	180	99

Figure S211. Get High-res Image Gene #78: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'DNMT3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.739 (Fisher's exact test), Q value = 1

Table S917. Gene #78: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
DNMT3A MUTATED	3	1	3	4
DNMT3A WILD-TYPE	124	118	103	152

'DNMT3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S918. Gene #78: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
DNMT3A MUTATED	1	1	3	1	1	4
DNMT3A WILD-TYPE	98	76	117	56	62	88

'TMEM184A MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S919. Gene #79: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TMEM184A MUTATED	1	2	0
TMEM184A WILD-TYPE	291	430	62

'TMEM184A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.278 (Fisher's exact test), Q value = 0.92

Table S920. Gene #79: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TMEM184A MUTATED	1	0	0	2
TMEM184A WILD-TYPE	152	223	88	159

'TMEM184A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S921. Gene #79: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TMEM184A MUTATED	0	1	1	1
TMEM184A WILD-TYPE	185	154	137	94

'TMEM184A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.784 (Fisher's exact test), Q value = 1

Table S922. Gene #79: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TMEM184A MUTATED	1	2	0
TMEM184A WILD-TYPE	204	218	148

'TMEM184A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.293 (Fisher's exact test), Q value = 0.93

Table S923. Gene #79: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
TMEM184A MUTATED	1	2	0
TMEM184A WILD-TYPE	237	189	228

'TMEM184A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S924. Gene #79: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
TMEM184A MUTATED	1	0	2
TMEM184A WILD-TYPE	195	191	268

'TMEM184A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S925. Gene #79: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
TMEM184A MUTATED	1	0	0	2
TMEM184A WILD-TYPE	139	107	83	180

'TMEM184A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.231 (Fisher's exact test), Q value = 0.89

Table S926. Gene #79: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
TMEM184A MUTATED	0	2	1
TMEM184A WILD-TYPE	223	184	102

'TMEM184A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S927. Gene #79: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
TMEM184A MUTATED	1	0	0	2
TMEM184A WILD-TYPE	126	119	106	154

'TMEM184A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.447 (Fisher's exact test), Q value = 1

Table S928. Gene #79: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
TMEM184A MUTATED	0	0	2	0	1	0
TMEM184A WILD-TYPE	99	77	118	57	62	92

'G6PC MUTATION STATUS' versus 'CN_CNMF'

P value = 0.473 (Fisher's exact test), Q value = 1

Table S929. Gene #80: 'G6PC MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
G6PC MUTATED	3	3	1
G6PC WILD-TYPE	289	429	61

'G6PC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S930. Gene #80: 'G6PC MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
G6PC MUTATED	3	1	1	2
G6PC WILD-TYPE	150	222	87	159

'G6PC MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 0.98

Table S931. Gene #80: 'G6PC MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
G6PC MUTATED	2	3	0	2
G6PC WILD-TYPE	183	152	138	93

'G6PC MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.801 (Fisher's exact test), Q value = 1

Table S932. Gene #80: 'G6PC MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
G6PC MUTATED	3	3	1
G6PC WILD-TYPE	202	217	147

'G6PC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S933. Gene #80: 'G6PC MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
G6PC MUTATED	3	2	2
G6PC WILD-TYPE	235	189	226

'G6PC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S934. Gene #80: 'G6PC MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
G6PC MUTATED	2	2	3
G6PC WILD-TYPE	194	189	267

'G6PC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.407 (Fisher's exact test), Q value = 1

Table S935. Gene #80: 'G6PC MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
G6PC MUTATED	0	2	1	3
G6PC WILD-TYPE	140	105	82	179

'G6PC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.147 (Fisher's exact test), Q value = 0.72

Table S936. Gene #80: 'G6PC MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
G6PC MUTATED	1	2	3
G6PC WILD-TYPE	222	184	100

'G6PC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.312 (Fisher's exact test), Q value = 0.94

Table S937. Gene #80: 'G6PC MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
G6PC MUTATED	1	0	1	4
G6PC WILD-TYPE	126	119	105	152

'G6PC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.735 (Fisher's exact test), Q value = 1

Table S938. Gene #80: 'G6PC MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
G6PC MUTATED	1	0	3	1	0	1
G6PC WILD-TYPE	98	77	117	56	63	91

'CYP11A1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 0.94

Table S939. Gene #81: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
CYP11A1 MUTATED	0	0	2	1
CYP11A1 WILD-TYPE	78	41	62	56

'CYP11A1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.891 (Fisher's exact test), Q value = 1

Table S940. Gene #81: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
CYP11A1 MUTATED	1	0	1	1
CYP11A1 WILD-TYPE	62	50	47	78

'CYP11A1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S941. Gene #81: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
CYP11A1 MUTATED	1	2	0	0
CYP11A1 WILD-TYPE	69	96	44	63

'CYP11A1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.312 (Fisher's exact test), Q value = 0.94

Table S942. Gene #81: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
CYP11A1 MUTATED	1	0	2
CYP11A1 WILD-TYPE	137	61	74

'CYP11A1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.473 (Fisher's exact test), Q value = 1

Table S943. Gene #81: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
CYP11A1 MUTATED	3	3	1
CYP11A1 WILD-TYPE	289	429	61

'CYP11A1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S944. Gene #81: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
CYP11A1 MUTATED	1	1	1	2
CYP11A1 WILD-TYPE	152	222	87	159

'CYP11A1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S945. Gene #81: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
CYP11A1 MUTATED	2	0	2	1
CYP11A1 WILD-TYPE	183	155	136	94

'CYP11A1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.45 (Fisher's exact test), Q value = 1

Table S946. Gene #81: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
CYP11A1 MUTATED	2	3	0
CYP11A1 WILD-TYPE	203	217	148

'CYP11A1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0731 (Fisher's exact test), Q value = 0.49

Table S947. Gene #81: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
CYP11A1 MUTATED	5	2	0
CYP11A1 WILD-TYPE	233	189	228

'CYP11A1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.389 (Fisher's exact test), Q value = 1

Table S948. Gene #81: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
CYP11A1 MUTATED	4	1	2
CYP11A1 WILD-TYPE	192	190	268

'CYP11A1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.911 (Fisher's exact test), Q value = 1

Table S949. Gene #81: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
CYP11A1 MUTATED	1	1	1	1
CYP11A1 WILD-TYPE	139	106	82	181

'CYP11A1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S950. Gene #81: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
CYP11A1 MUTATED	1	2	1
CYP11A1 WILD-TYPE	222	184	102

'CYP11A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.579 (Fisher's exact test), Q value = 1

Table S951. Gene #81: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
CYP11A1 MUTATED	0	2	1	1
CYP11A1 WILD-TYPE	127	117	105	155

'CYP11A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.858 (Fisher's exact test), Q value = 1

Table S952. Gene #81: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
CYP11A1 MUTATED	0	1	1	0	1	1
CYP11A1 WILD-TYPE	99	76	119	57	62	91

'KRT15 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.735 (Fisher's exact test), Q value = 1

Table S953. Gene #82: 'KRT15 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
KRT15 MUTATED	2	6	0
KRT15 WILD-TYPE	290	426	62

'KRT15 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.555 (Fisher's exact test), Q value = 1

Table S954. Gene #82: 'KRT15 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
KRT15 MUTATED	0	3	1	2
KRT15 WILD-TYPE	153	220	87	159

'KRT15 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S955. Gene #82: 'KRT15 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
KRT15 MUTATED	1	1	1	1
KRT15 WILD-TYPE	184	154	137	94

'KRT15 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S956. Gene #82: 'KRT15 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
KRT15 MUTATED	2	1	1
KRT15 WILD-TYPE	203	219	147

'KRT15 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.514 (Fisher's exact test), Q value = 1

Table S957. Gene #82: 'KRT15 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
KRT15 MUTATED	3	3	1
KRT15 WILD-TYPE	235	188	227

'KRT15 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S958. Gene #82: 'KRT15 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
KRT15 MUTATED	2	2	3
KRT15 WILD-TYPE	194	189	267

'KRT15 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.517 (Fisher's exact test), Q value = 1

Table S959. Gene #82: 'KRT15 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
KRT15 MUTATED	3	0	1	2
KRT15 WILD-TYPE	137	107	82	180

'KRT15 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.867 (Fisher's exact test), Q value = 1

Table S960. Gene #82: 'KRT15 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
KRT15 MUTATED	2	3	1
KRT15 WILD-TYPE	221	183	102

'KRT15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.947 (Fisher's exact test), Q value = 1

Table S961. Gene #82: 'KRT15 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
KRT15 MUTATED	1	2	1	2
KRT15 WILD-TYPE	126	117	105	154

'KRT15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.864 (Fisher's exact test), Q value = 1

Table S962. Gene #82: 'KRT15 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
KRT15 MUTATED	1	1	2	1	1	0
KRT15 WILD-TYPE	98	76	118	56	62	92

'CMA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S963. Gene #83: 'CMA1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
CMA1 MUTATED	2	1	0
CMA1 WILD-TYPE	290	431	62

'CMA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.45 (Fisher's exact test), Q value = 1

Table S964. Gene #83: 'CMA1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
CMA1 MUTATED	2	1	0	0
CMA1 WILD-TYPE	151	222	88	161

'CMA1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S965. Gene #83: 'CMA1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
CMA1 MUTATED	1	1	1	0
CMA1 WILD-TYPE	184	154	137	95

'CMA1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S966. Gene #83: 'CMA1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
CMA1 MUTATED	1	1	1
CMA1 WILD-TYPE	204	219	147

'MAP3K12 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S967. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
MAP3K12 MUTATED	2	4	0
MAP3K12 WILD-TYPE	290	428	62

'MAP3K12 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.447 (Fisher's exact test), Q value = 1

Table S968. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
MAP3K12 MUTATED	1	1	0	3
MAP3K12 WILD-TYPE	152	222	88	158

'MAP3K12 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.531 (Fisher's exact test), Q value = 1

Table S969. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
MAP3K12 MUTATED	3	1	0	1
MAP3K12 WILD-TYPE	182	154	138	94

'MAP3K12 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S970. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
MAP3K12 MUTATED	2	2	1
MAP3K12 WILD-TYPE	203	218	147

'MAP3K12 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S971. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
MAP3K12 MUTATED	1	3	1
MAP3K12 WILD-TYPE	237	188	227

'MAP3K12 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.339 (Fisher's exact test), Q value = 0.98

Table S972. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
MAP3K12 MUTATED	0	2	3
MAP3K12 WILD-TYPE	196	189	267

'MAP3K12 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.486 (Fisher's exact test), Q value = 1

Table S973. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
MAP3K12 MUTATED	0	1	1	3
MAP3K12 WILD-TYPE	140	106	82	179

'MAP3K12 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S974. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
MAP3K12 MUTATED	1	3	1
MAP3K12 WILD-TYPE	222	183	102

'MAP3K12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 0.73

Table S975. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
MAP3K12 MUTATED	0	0	2	3
MAP3K12 WILD-TYPE	127	119	104	153

'MAP3K12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.185 (Fisher's exact test), Q value = 0.83

Table S976. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
MAP3K12 MUTATED	0	0	1	1	0	3
MAP3K12 WILD-TYPE	99	77	119	56	63	89

'TREML2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.136 (Fisher's exact test), Q value = 0.7

Table S977. Gene #85: 'TREML2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
TREML2 MUTATED	0	1	0	2
TREML2 WILD-TYPE	78	40	64	55

'TREML2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S978. Gene #85: 'TREML2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
TREML2 MUTATED	1	1	0	1
TREML2 WILD-TYPE	62	49	48	78

'TREML2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.645 (Fisher's exact test), Q value = 1

Table S979. Gene #85: 'TREML2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
TREML2 MUTATED	0	2	1	1
TREML2 WILD-TYPE	70	96	43	62

'TREML2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S980. Gene #85: 'TREML2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TREML2 MUTATED	3	0	1
TREML2 WILD-TYPE	135	61	75

'TREML2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S981. Gene #85: 'TREML2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TREML2 MUTATED	3	3	0
TREML2 WILD-TYPE	289	429	62

'TREML2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S982. Gene #85: 'TREML2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TREML2 MUTATED	2	1	0	1
TREML2 WILD-TYPE	151	222	88	160

'TREML2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S983. Gene #85: 'TREML2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TREML2 MUTATED	2	2	2	0
TREML2 WILD-TYPE	183	153	136	95

'TREML2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S984. Gene #85: 'TREML2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TREML2 MUTATED	2	2	2
TREML2 WILD-TYPE	203	218	146

'TREML2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.391 (Fisher's exact test), Q value = 1

Table S985. Gene #85: 'TREML2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
TREML2 MUTATED	4	1	1
TREML2 WILD-TYPE	234	190	227

'TREML2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S986. Gene #85: 'TREML2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
TREML2 MUTATED	3	1	2
TREML2 WILD-TYPE	193	190	268

'TREML2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.52 (Fisher's exact test), Q value = 1

Table S987. Gene #85: 'TREML2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
TREML2 MUTATED	0	1	1	1
TREML2 WILD-TYPE	140	106	82	181

'TREML2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S988. Gene #85: 'TREML2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
TREML2 MUTATED	1	1	1
TREML2 WILD-TYPE	222	185	102

'TREML2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S989. Gene #85: 'TREML2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
TREML2 MUTATED	0	0	1	2
TREML2 WILD-TYPE	127	119	105	154

'TREML2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S990. Gene #85: 'TREML2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
TREML2 MUTATED	0	0	1	1	0	1
TREML2 WILD-TYPE	99	77	119	56	63	91

'PRCP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.501 (Fisher's exact test), Q value = 1

Table S991. Gene #86: 'PRCP MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PRCP MUTATED	3	1	0
PRCP WILD-TYPE	289	431	62

'PRCP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0175 (Fisher's exact test), Q value = 0.21

Table S992. Gene #86: 'PRCP MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
PRCP MUTATED	3	0	0	0
PRCP WILD-TYPE	150	223	88	161

Figure S212. Get High-res Image Gene #86: 'PRCP MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'PRCP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S993. Gene #86: 'PRCP MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PRCP MUTATED	1	1	1	0
PRCP WILD-TYPE	184	154	137	95

'PRCP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.267 (Fisher's exact test), Q value = 0.91

Table S994. Gene #86: 'PRCP MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PRCP MUTATED	0	1	2
PRCP WILD-TYPE	205	219	146

'PRCP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.514 (Fisher's exact test), Q value = 1

Table S995. Gene #86: 'PRCP MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
PRCP MUTATED	2	1	0
PRCP WILD-TYPE	236	190	228

'PRCP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S996. Gene #86: 'PRCP MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
PRCP MUTATED	2	0	1
PRCP WILD-TYPE	194	191	269

'ESR2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S997. Gene #87: 'ESR2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
ESR2 MUTATED	1	0	1	1
ESR2 WILD-TYPE	77	41	63	56

'ESR2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.701 (Fisher's exact test), Q value = 1

Table S998. Gene #87: 'ESR2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
ESR2 MUTATED	0	1	1	1
ESR2 WILD-TYPE	63	49	47	78

'ESR2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S999. Gene #87: 'ESR2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
ESR2 MUTATED	1	1	1	0
ESR2 WILD-TYPE	69	97	43	63

'ESR2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S1000. Gene #87: 'ESR2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
ESR2 MUTATED	3	0	0
ESR2 WILD-TYPE	135	61	76

'ESR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S1001. Gene #87: 'ESR2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ESR2 MUTATED	3	2	0
ESR2 WILD-TYPE	289	430	62

'ESR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.756 (Fisher's exact test), Q value = 1

Table S1002. Gene #87: 'ESR2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ESR2 MUTATED	2	1	0	1
ESR2 WILD-TYPE	151	222	88	160

'ESR2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S1003. Gene #87: 'ESR2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ESR2 MUTATED	3	0	1	1
ESR2 WILD-TYPE	182	155	137	94

'ESR2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.747 (Fisher's exact test), Q value = 1

Table S1004. Gene #87: 'ESR2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ESR2 MUTATED	1	3	1
ESR2 WILD-TYPE	204	217	147

'ESR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.559 (Fisher's exact test), Q value = 1

Table S1005. Gene #87: 'ESR2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
ESR2 MUTATED	2	0	2
ESR2 WILD-TYPE	236	191	226

'ESR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S1006. Gene #87: 'ESR2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
ESR2 MUTATED	1	2	1
ESR2 WILD-TYPE	195	189	269

'ESR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.155 (Fisher's exact test), Q value = 0.74

Table S1007. Gene #87: 'ESR2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
ESR2 MUTATED	1	2	0	0
ESR2 WILD-TYPE	139	105	83	182

'ESR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S1008. Gene #87: 'ESR2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
ESR2 MUTATED	2	0	1
ESR2 WILD-TYPE	221	186	102

'ESR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1009. Gene #87: 'ESR2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
ESR2 MUTATED	1	1	0	1
ESR2 WILD-TYPE	126	118	106	155

'ESR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.225 (Fisher's exact test), Q value = 0.88

Table S1010. Gene #87: 'ESR2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
ESR2 MUTATED	0	1	0	0	0	2
ESR2 WILD-TYPE	99	76	120	57	63	90

'POM121 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00686 (Fisher's exact test), Q value = 0.11

Table S1011. Gene #88: 'POM121 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
POM121 MUTATED	2	1	3
POM121 WILD-TYPE	290	431	59

Figure S213. Get High-res Image Gene #88: 'POM121 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'POM121 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.354 (Fisher's exact test), Q value = 1

Table S1012. Gene #88: 'POM121 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
POM121 MUTATED	2	1	1	0
POM121 WILD-TYPE	151	222	87	161

'POM121 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S1013. Gene #88: 'POM121 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
POM121 MUTATED	3	1	0	0
POM121 WILD-TYPE	182	154	138	95

'POM121 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.141 (Fisher's exact test), Q value = 0.71

Table S1014. Gene #88: 'POM121 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
POM121 MUTATED	3	0	1
POM121 WILD-TYPE	202	220	147

'POM121 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.632 (Fisher's exact test), Q value = 1

Table S1015. Gene #88: 'POM121 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
POM121 MUTATED	3	1	1
POM121 WILD-TYPE	235	190	227

'POM121 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S1016. Gene #88: 'POM121 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
POM121 MUTATED	2	2	1
POM121 WILD-TYPE	194	189	269

'POM121 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S1017. Gene #88: 'POM121 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
POM121 MUTATED	1	2	0	1
POM121 WILD-TYPE	139	105	83	181

'POM121 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.339 (Fisher's exact test), Q value = 0.98

Table S1018. Gene #88: 'POM121 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
POM121 MUTATED	1	1	2
POM121 WILD-TYPE	222	185	101

'POM121 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.784 (Fisher's exact test), Q value = 1

Table S1019. Gene #88: 'POM121 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
POM121 MUTATED	0	1	1	2
POM121 WILD-TYPE	127	118	105	154

'POM121 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.971 (Fisher's exact test), Q value = 1

Table S1020. Gene #88: 'POM121 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
POM121 MUTATED	1	0	1	0	1	1
POM121 WILD-TYPE	98	77	119	57	62	91

'MACC1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S1021. Gene #89: 'MACC1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
MACC1 MUTATED	1	0	2	0
MACC1 WILD-TYPE	77	41	62	57

'MACC1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.116 (Fisher's exact test), Q value = 0.64

Table S1022. Gene #89: 'MACC1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
MACC1 MUTATED	1	0	2	0
MACC1 WILD-TYPE	62	50	46	79

'MACC1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.067 (Fisher's exact test), Q value = 0.47

Table S1023. Gene #89: 'MACC1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
MACC1 MUTATED	1	0	0	3
MACC1 WILD-TYPE	69	98	44	60

'MACC1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.258 (Fisher's exact test), Q value = 0.91

Table S1024. Gene #89: 'MACC1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
MACC1 MUTATED	2	2	0
MACC1 WILD-TYPE	136	59	76

'MACC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 0.64

Table S1025. Gene #89: 'MACC1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
MACC1 MUTATED	6	2	0
MACC1 WILD-TYPE	286	430	62

'MACC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.109 (Fisher's exact test), Q value = 0.63

Table S1026. Gene #89: 'MACC1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
MACC1 MUTATED	4	2	0	0
MACC1 WILD-TYPE	149	221	88	161

'MACC1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.064 (Fisher's exact test), Q value = 0.46

Table S1027. Gene #89: 'MACC1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
MACC1 MUTATED	1	0	1	3
MACC1 WILD-TYPE	184	155	137	92

'MACC1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.188 (Fisher's exact test), Q value = 0.83

Table S1028. Gene #89: 'MACC1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
MACC1 MUTATED	4	1	0
MACC1 WILD-TYPE	201	219	148

'MACC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.253 (Fisher's exact test), Q value = 0.9

Table S1029. Gene #89: 'MACC1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
MACC1 MUTATED	4	0	2
MACC1 WILD-TYPE	234	191	226

'MACC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0576 (Fisher's exact test), Q value = 0.44

Table S1030. Gene #89: 'MACC1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
MACC1 MUTATED	3	3	0
MACC1 WILD-TYPE	193	188	270

'MACC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.194 (Fisher's exact test), Q value = 0.83

Table S1031. Gene #89: 'MACC1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
MACC1 MUTATED	1	2	1	0
MACC1 WILD-TYPE	139	105	82	182

'MACC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.196 (Fisher's exact test), Q value = 0.83

Table S1032. Gene #89: 'MACC1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
MACC1 MUTATED	2	0	2
MACC1 WILD-TYPE	221	186	101

'MACC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1033. Gene #89: 'MACC1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
MACC1 MUTATED	1	1	1	1
MACC1 WILD-TYPE	126	118	105	155

'MACC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.714 (Fisher's exact test), Q value = 1

Table S1034. Gene #89: 'MACC1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
MACC1 MUTATED	1	1	0	0	1	1
MACC1 WILD-TYPE	98	76	120	57	62	91

'QKI MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.143 (Fisher's exact test), Q value = 0.71

Table S1035. Gene #90: 'QKI MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
QKI MUTATED	4	0	0	1
QKI WILD-TYPE	74	41	64	56

'QKI MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0597 (Fisher's exact test), Q value = 0.45

Table S1036. Gene #90: 'QKI MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
QKI MUTATED	4	0	0	1
QKI WILD-TYPE	59	50	48	78

'QKI MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S1037. Gene #90: 'QKI MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
QKI MUTATED	1	2	0	2
QKI WILD-TYPE	69	96	44	61

'QKI MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1038. Gene #90: 'QKI MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
QKI MUTATED	3	1	1
QKI WILD-TYPE	135	60	75

'QKI MUTATION STATUS' versus 'CN_CNMF'

P value = 0.152 (Fisher's exact test), Q value = 0.73

Table S1039. Gene #90: 'QKI MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
QKI MUTATED	4	1	1
QKI WILD-TYPE	288	431	61

'QKI MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.356 (Fisher's exact test), Q value = 1

Table S1040. Gene #90: 'QKI MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
QKI MUTATED	2	1	1	0
QKI WILD-TYPE	151	222	87	161

'QKI MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.914 (Fisher's exact test), Q value = 1

Table S1041. Gene #90: 'QKI MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
QKI MUTATED	2	1	1	0
QKI WILD-TYPE	183	154	137	95

'QKI MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.57 (Fisher's exact test), Q value = 1

Table S1042. Gene #90: 'QKI MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
QKI MUTATED	1	1	2
QKI WILD-TYPE	204	219	146

'QKI MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S1043. Gene #90: 'QKI MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
QKI MUTATED	2	0	1
QKI WILD-TYPE	236	191	227

'QKI MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.273 (Fisher's exact test), Q value = 0.91

Table S1044. Gene #90: 'QKI MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
QKI MUTATED	2	1	0
QKI WILD-TYPE	194	190	270

'AOX1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.327 (Fisher's exact test), Q value = 0.97

Table S1045. Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
AOX1 MUTATED	0	1	1	2
AOX1 WILD-TYPE	78	40	63	55

'AOX1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.278 (Fisher's exact test), Q value = 0.92

Table S1046. Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
AOX1 MUTATED	0	2	0	2
AOX1 WILD-TYPE	63	48	48	77

'AOX1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.763 (Fisher's exact test), Q value = 1

Table S1047. Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
AOX1 MUTATED	1	2	1	0
AOX1 WILD-TYPE	69	96	43	63

'AOX1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.185 (Fisher's exact test), Q value = 0.83

Table S1048. Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
AOX1 MUTATED	4	0	0
AOX1 WILD-TYPE	134	61	76

'AOX1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 0.64

Table S1049. Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
AOX1 MUTATED	6	2	0
AOX1 WILD-TYPE	286	430	62

'AOX1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.482 (Fisher's exact test), Q value = 1

Table S1050. Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
AOX1 MUTATED	2	2	0	0
AOX1 WILD-TYPE	151	221	88	161

'AOX1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.578 (Fisher's exact test), Q value = 1

Table S1051. Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
AOX1 MUTATED	1	1	2	2
AOX1 WILD-TYPE	184	154	136	93

'AOX1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.886 (Fisher's exact test), Q value = 1

Table S1052. Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
AOX1 MUTATED	2	3	1
AOX1 WILD-TYPE	203	217	147

'AOX1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00663 (Fisher's exact test), Q value = 0.11

Table S1053. Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
AOX1 MUTATED	7	1	0
AOX1 WILD-TYPE	231	190	228

Figure S214. Get High-res Image Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'AOX1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.105 (Fisher's exact test), Q value = 0.61

Table S1054. Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
AOX1 MUTATED	5	2	1
AOX1 WILD-TYPE	191	189	269

'AOX1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0442 (Fisher's exact test), Q value = 0.39

Table S1055. Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
AOX1 MUTATED	1	3	0	0
AOX1 WILD-TYPE	139	104	83	182

Figure S215. Get High-res Image Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'AOX1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0277 (Fisher's exact test), Q value = 0.29

Table S1056. Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
AOX1 MUTATED	1	0	3
AOX1 WILD-TYPE	222	186	100

Figure S216. Get High-res Image Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'AOX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.674 (Fisher's exact test), Q value = 1

Table S1057. Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
AOX1 MUTATED	1	2	0	1
AOX1 WILD-TYPE	126	117	106	155

'AOX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.273 (Fisher's exact test), Q value = 0.91

Table S1058. Gene #91: 'AOX1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
AOX1 MUTATED	0	1	0	0	1	2
AOX1 WILD-TYPE	99	76	120	57	62	90

'KRAS MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1059. Gene #92: 'KRAS MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
KRAS MUTATED	2	2	0
KRAS WILD-TYPE	290	430	62

'KRAS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1060. Gene #92: 'KRAS MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
KRAS MUTATED	1	1	0	1
KRAS WILD-TYPE	152	222	88	160

'KRAS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1061. Gene #92: 'KRAS MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
KRAS MUTATED	1	1	1	0
KRAS WILD-TYPE	184	154	137	95

'KRAS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.364 (Fisher's exact test), Q value = 1

Table S1062. Gene #92: 'KRAS MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
KRAS MUTATED	2	0	1
KRAS WILD-TYPE	203	220	147

'KRAS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1063. Gene #92: 'KRAS MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
KRAS MUTATED	1	1	1
KRAS WILD-TYPE	237	190	227

'KRAS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.784 (Fisher's exact test), Q value = 1

Table S1064. Gene #92: 'KRAS MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
KRAS MUTATED	1	0	2
KRAS WILD-TYPE	195	191	268

'TYRP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.811 (Fisher's exact test), Q value = 1

Table S1065. Gene #93: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TYRP1 MUTATED	3	3	0
TYRP1 WILD-TYPE	289	429	62

'TYRP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.868 (Fisher's exact test), Q value = 1

Table S1066. Gene #93: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TYRP1 MUTATED	2	2	0	1
TYRP1 WILD-TYPE	151	221	88	160

'TYRP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1067. Gene #93: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TYRP1 MUTATED	1	1	1	0
TYRP1 WILD-TYPE	184	154	137	95

'TYRP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.366 (Fisher's exact test), Q value = 1

Table S1068. Gene #93: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TYRP1 MUTATED	2	0	1
TYRP1 WILD-TYPE	203	220	147

'TYRP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.391 (Fisher's exact test), Q value = 1

Table S1069. Gene #93: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
TYRP1 MUTATED	4	1	1
TYRP1 WILD-TYPE	234	190	227

'TYRP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S1070. Gene #93: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
TYRP1 MUTATED	2	3	1
TYRP1 WILD-TYPE	194	188	269

'TYRP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S1071. Gene #93: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
TYRP1 MUTATED	0	2	0	2
TYRP1 WILD-TYPE	140	105	83	180

'TYRP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.339 (Fisher's exact test), Q value = 0.98

Table S1072. Gene #93: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
TYRP1 MUTATED	1	1	2
TYRP1 WILD-TYPE	222	185	101

'TYRP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.909 (Fisher's exact test), Q value = 1

Table S1073. Gene #93: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
TYRP1 MUTATED	1	1	0	2
TYRP1 WILD-TYPE	126	118	106	154

'TYRP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.47 (Fisher's exact test), Q value = 1

Table S1074. Gene #93: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
TYRP1 MUTATED	0	0	1	0	1	2
TYRP1 WILD-TYPE	99	77	119	57	62	90

'EMG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S1075. Gene #94: 'EMG1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
EMG1 MUTATED	1	4	0
EMG1 WILD-TYPE	291	428	62

'EMG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.344 (Fisher's exact test), Q value = 0.99

Table S1076. Gene #94: 'EMG1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
EMG1 MUTATED	0	2	0	3
EMG1 WILD-TYPE	153	221	88	158

'EMG1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.307 (Fisher's exact test), Q value = 0.94

Table S1077. Gene #94: 'EMG1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
EMG1 MUTATED	2	3	0	0
EMG1 WILD-TYPE	183	152	138	95

'EMG1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S1078. Gene #94: 'EMG1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
EMG1 MUTATED	3	1	1
EMG1 WILD-TYPE	202	219	147

'EMG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0594 (Fisher's exact test), Q value = 0.45

Table S1079. Gene #94: 'EMG1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
EMG1 MUTATED	0	1	4
EMG1 WILD-TYPE	238	190	224

'EMG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.153 (Fisher's exact test), Q value = 0.73

Table S1080. Gene #94: 'EMG1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
EMG1 MUTATED	0	1	4
EMG1 WILD-TYPE	196	190	266

'EMG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 1

Table S1081. Gene #94: 'EMG1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
EMG1 MUTATED	1	0	2	2
EMG1 WILD-TYPE	139	107	81	180

'EMG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.287 (Fisher's exact test), Q value = 0.93

Table S1082. Gene #94: 'EMG1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
EMG1 MUTATED	4	1	0
EMG1 WILD-TYPE	219	185	103

'EMG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.189 (Fisher's exact test), Q value = 0.83

Table S1083. Gene #94: 'EMG1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
EMG1 MUTATED	1	0	3	1
EMG1 WILD-TYPE	126	119	103	155

'EMG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.266 (Fisher's exact test), Q value = 0.91

Table S1084. Gene #94: 'EMG1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
EMG1 MUTATED	1	1	0	2	0	1
EMG1 WILD-TYPE	98	76	120	55	63	91

'HEATR3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.83

Table S1085. Gene #95: 'HEATR3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
HEATR3 MUTATED	2	1	1
HEATR3 WILD-TYPE	290	431	61

'HEATR3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.232 (Fisher's exact test), Q value = 0.89

Table S1086. Gene #95: 'HEATR3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
HEATR3 MUTATED	2	0	0	1
HEATR3 WILD-TYPE	151	223	88	160

'HEATR3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.623 (Fisher's exact test), Q value = 1

Table S1087. Gene #95: 'HEATR3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
HEATR3 MUTATED	2	0	1	0
HEATR3 WILD-TYPE	183	155	137	95

'HEATR3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.627 (Fisher's exact test), Q value = 1

Table S1088. Gene #95: 'HEATR3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
HEATR3 MUTATED	2	1	0
HEATR3 WILD-TYPE	203	219	148

'HEATR3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S1089. Gene #95: 'HEATR3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
HEATR3 MUTATED	2	0	1
HEATR3 WILD-TYPE	236	191	227

'HEATR3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1090. Gene #95: 'HEATR3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
HEATR3 MUTATED	1	1	1
HEATR3 WILD-TYPE	195	190	269

'CDKN2A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.813 (Fisher's exact test), Q value = 1

Table S1091. Gene #96: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
CDKN2A MUTATED	3	3	0
CDKN2A WILD-TYPE	289	429	62

'CDKN2A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1092. Gene #96: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
CDKN2A MUTATED	1	2	0	1
CDKN2A WILD-TYPE	152	221	88	160

'CDKN2A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S1093. Gene #96: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
CDKN2A MUTATED	2	0	1	1
CDKN2A WILD-TYPE	183	155	137	94

'CDKN2A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S1094. Gene #96: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
CDKN2A MUTATED	2	2	0
CDKN2A WILD-TYPE	203	218	148

'CDKN2A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.293 (Fisher's exact test), Q value = 0.93

Table S1095. Gene #96: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
CDKN2A MUTATED	3	0	3
CDKN2A WILD-TYPE	235	191	225

'CDKN2A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.388 (Fisher's exact test), Q value = 1

Table S1096. Gene #96: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
CDKN2A MUTATED	2	3	1
CDKN2A WILD-TYPE	194	188	269

'CDKN2A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0221 (Fisher's exact test), Q value = 0.24

Table S1097. Gene #96: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
CDKN2A MUTATED	0	3	1	0
CDKN2A WILD-TYPE	140	104	82	182

Figure S217. Get High-res Image Gene #96: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'CDKN2A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.262 (Fisher's exact test), Q value = 0.91

Table S1098. Gene #96: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
CDKN2A MUTATED	3	0	1
CDKN2A WILD-TYPE	220	186	102

'CDKN2A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.49 (Fisher's exact test), Q value = 1

Table S1099. Gene #96: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
CDKN2A MUTATED	0	1	2	1
CDKN2A WILD-TYPE	127	118	104	155

'CDKN2A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.241 (Fisher's exact test), Q value = 0.89

Table S1100. Gene #96: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
CDKN2A MUTATED	0	1	0	1	0	2
CDKN2A WILD-TYPE	99	76	120	56	63	90

'SLC35A2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1101. Gene #97: 'SLC35A2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SLC35A2 MUTATED	1	2	0
SLC35A2 WILD-TYPE	291	430	62

'SLC35A2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1102. Gene #97: 'SLC35A2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SLC35A2 MUTATED	1	1	1
SLC35A2 WILD-TYPE	237	190	227

'SLC35A2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1103. Gene #97: 'SLC35A2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SLC35A2 MUTATED	1	1	1
SLC35A2 WILD-TYPE	195	190	269

'MYH8 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.717 (Fisher's exact test), Q value = 1

Table S1104. Gene #98: 'MYH8 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
MYH8 MUTATED	3	0	1	1
MYH8 WILD-TYPE	75	41	63	56

'MYH8 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.731 (Fisher's exact test), Q value = 1

Table S1105. Gene #98: 'MYH8 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
MYH8 MUTATED	1	1	2	1
MYH8 WILD-TYPE	62	49	46	78

'MYH8 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.259 (Fisher's exact test), Q value = 0.91

Table S1106. Gene #98: 'MYH8 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
MYH8 MUTATED	3	1	0	3
MYH8 WILD-TYPE	67	97	44	60

'MYH8 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.0877 (Fisher's exact test), Q value = 0.55

Table S1107. Gene #98: 'MYH8 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
MYH8 MUTATED	1	3	3
MYH8 WILD-TYPE	137	58	73

'MYH8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.613 (Fisher's exact test), Q value = 1

Table S1108. Gene #98: 'MYH8 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
MYH8 MUTATED	10	10	1
MYH8 WILD-TYPE	282	422	61

'MYH8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0998 (Fisher's exact test), Q value = 0.6

Table S1109. Gene #98: 'MYH8 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
MYH8 MUTATED	8	7	0	3
MYH8 WILD-TYPE	145	216	88	158

'MYH8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S1110. Gene #98: 'MYH8 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
MYH8 MUTATED	7	2	4	1
MYH8 WILD-TYPE	178	153	134	94

'MYH8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.229 (Fisher's exact test), Q value = 0.89

Table S1111. Gene #98: 'MYH8 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
MYH8 MUTATED	7	6	1
MYH8 WILD-TYPE	198	214	147

'MYH8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.102 (Fisher's exact test), Q value = 0.6

Table S1112. Gene #98: 'MYH8 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
MYH8 MUTATED	9	6	2
MYH8 WILD-TYPE	229	185	226

'MYH8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.452 (Fisher's exact test), Q value = 1

Table S1113. Gene #98: 'MYH8 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
MYH8 MUTATED	5	7	5
MYH8 WILD-TYPE	191	184	265

'MYH8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S1114. Gene #98: 'MYH8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
MYH8 MUTATED	4	4	2	4
MYH8 WILD-TYPE	136	103	81	178

'MYH8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.252 (Fisher's exact test), Q value = 0.9

Table S1115. Gene #98: 'MYH8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
MYH8 MUTATED	6	3	5
MYH8 WILD-TYPE	217	183	98

'MYH8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S1116. Gene #98: 'MYH8 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
MYH8 MUTATED	2	4	2	6
MYH8 WILD-TYPE	125	115	104	150

'MYH8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S1117. Gene #98: 'MYH8 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
MYH8 MUTATED	2	4	3	0	3	2
MYH8 WILD-TYPE	97	73	117	57	60	90

'SMARCA4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00095 (Fisher's exact test), Q value = 0.023

Table S1118. Gene #99: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SMARCA4 MUTATED	3	24	0
SMARCA4 WILD-TYPE	289	408	62

Figure S218. Get High-res Image Gene #99: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'SMARCA4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00579 (Fisher's exact test), Q value = 0.1

Table S1119. Gene #99: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SMARCA4 MUTATED	3	17	0	7
SMARCA4 WILD-TYPE	150	206	88	154

Figure S219. Get High-res Image Gene #99: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'SMARCA4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.535 (Fisher's exact test), Q value = 1

Table S1120. Gene #99: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
SMARCA4 MUTATED	8	6	4	1
SMARCA4 WILD-TYPE	177	149	134	94

'SMARCA4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S1121. Gene #99: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
SMARCA4 MUTATED	8	6	5
SMARCA4 WILD-TYPE	197	214	143

'SMARCA4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0143 (Fisher's exact test), Q value = 0.18

Table S1122. Gene #99: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SMARCA4 MUTATED	4	7	16
SMARCA4 WILD-TYPE	234	184	212

Figure S220. Get High-res Image Gene #99: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'SMARCA4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00934 (Fisher's exact test), Q value = 0.14

Table S1123. Gene #99: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SMARCA4 MUTATED	2	13	12
SMARCA4 WILD-TYPE	194	178	258

Figure S221. Get High-res Image Gene #99: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'SMARCA4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.31 (Fisher's exact test), Q value = 0.94

Table S1124. Gene #99: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
SMARCA4 MUTATED	8	2	6	9
SMARCA4 WILD-TYPE	132	105	77	173

'SMARCA4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.243 (Fisher's exact test), Q value = 0.89

Table S1125. Gene #99: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
SMARCA4 MUTATED	14	9	2
SMARCA4 WILD-TYPE	209	177	101

'SMARCA4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0216 (Fisher's exact test), Q value = 0.24

Table S1126. Gene #99: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
SMARCA4 MUTATED	2	6	11	6
SMARCA4 WILD-TYPE	125	113	95	150

Figure S222. Get High-res Image Gene #99: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'SMARCA4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.18 (Fisher's exact test), Q value = 0.82

Table S1127. Gene #99: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
SMARCA4 MUTATED	9	2	4	2	1	7
SMARCA4 WILD-TYPE	90	75	116	55	62	85

'DOCK5 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.366 (Fisher's exact test), Q value = 1

Table S1128. Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
DOCK5 MUTATED	4	3	1	1
DOCK5 WILD-TYPE	74	38	63	56

'DOCK5 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.907 (Fisher's exact test), Q value = 1

Table S1129. Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
DOCK5 MUTATED	2	2	1	4
DOCK5 WILD-TYPE	61	48	47	75

'DOCK5 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.214 (Fisher's exact test), Q value = 0.86

Table S1130. Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
DOCK5 MUTATED	4	2	0	4
DOCK5 WILD-TYPE	66	96	44	59

'DOCK5 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.301 (Fisher's exact test), Q value = 0.94

Table S1131. Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
DOCK5 MUTATED	3	4	3
DOCK5 WILD-TYPE	135	57	73

'DOCK5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0133 (Fisher's exact test), Q value = 0.18

Table S1132. Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
DOCK5 MUTATED	13	5	1
DOCK5 WILD-TYPE	279	427	61

Figure S223. Get High-res Image Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'DOCK5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00993 (Fisher's exact test), Q value = 0.14

Table S1133. Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
DOCK5 MUTATED	8	4	1	0
DOCK5 WILD-TYPE	145	219	87	161

Figure S224. Get High-res Image Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'DOCK5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 0.83

Table S1134. Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
DOCK5 MUTATED	4	1	6	3
DOCK5 WILD-TYPE	181	154	132	92

'DOCK5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.166 (Fisher's exact test), Q value = 0.78

Table S1135. Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
DOCK5 MUTATED	8	5	1
DOCK5 WILD-TYPE	197	215	147

'DOCK5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00372 (Fisher's exact test), Q value = 0.075

Table S1136. Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
DOCK5 MUTATED	13	2	2
DOCK5 WILD-TYPE	225	189	226

Figure S225. Get High-res Image Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'DOCK5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00527 (Fisher's exact test), Q value = 0.097

Table S1137. Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
DOCK5 MUTATED	11	4	2
DOCK5 WILD-TYPE	185	187	268

Figure S226. Get High-res Image Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'DOCK5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0354 (Fisher's exact test), Q value = 0.33

Table S1138. Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
DOCK5 MUTATED	2	6	0	2
DOCK5 WILD-TYPE	138	101	83	180

Figure S227. Get High-res Image Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'DOCK5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0595 (Fisher's exact test), Q value = 0.45

Table S1139. Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
DOCK5 MUTATED	2	3	5
DOCK5 WILD-TYPE	221	183	98

'DOCK5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.388 (Fisher's exact test), Q value = 1

Table S1140. Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
DOCK5 MUTATED	3	3	0	4
DOCK5 WILD-TYPE	124	116	106	152

'DOCK5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.188 (Fisher's exact test), Q value = 0.83

Table S1141. Gene #100: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
DOCK5 MUTATED	1	1	1	0	3	4
DOCK5 WILD-TYPE	98	76	119	57	60	88

'PAK1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S1142. Gene #101: 'PAK1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PAK1 MUTATED	2	1	0
PAK1 WILD-TYPE	290	431	62

'PAK1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S1143. Gene #101: 'PAK1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
PAK1 MUTATED	2	1	0	0
PAK1 WILD-TYPE	151	222	88	161

'PAK1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 0.94

Table S1144. Gene #101: 'PAK1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PAK1 MUTATED	2	0	0	1
PAK1 WILD-TYPE	183	155	138	94

'PAK1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S1145. Gene #101: 'PAK1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PAK1 MUTATED	2	1	0
PAK1 WILD-TYPE	203	219	148

'KRT13 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.546 (Fisher's exact test), Q value = 1

Table S1146. Gene #102: 'KRT13 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
KRT13 MUTATED	1	0	2	0
KRT13 WILD-TYPE	77	41	62	57

'KRT13 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.117 (Fisher's exact test), Q value = 0.64

Table S1147. Gene #102: 'KRT13 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
KRT13 MUTATED	1	0	2	0
KRT13 WILD-TYPE	62	50	46	79

'KRT13 MUTATION STATUS' versus 'MIR_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1148. Gene #102: 'KRT13 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
KRT13 MUTATED	1	1	0	1
KRT13 WILD-TYPE	69	97	44	62

'KRT13 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.0716 (Fisher's exact test), Q value = 0.48

Table S1149. Gene #102: 'KRT13 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
KRT13 MUTATED	0	2	1
KRT13 WILD-TYPE	138	59	75

'KRT13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.419 (Fisher's exact test), Q value = 1

Table S1150. Gene #102: 'KRT13 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
KRT13 MUTATED	4	2	0
KRT13 WILD-TYPE	288	430	62

'KRT13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S1151. Gene #102: 'KRT13 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
KRT13 MUTATED	2	2	0	0
KRT13 WILD-TYPE	151	221	88	161

'KRT13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 0.85

Table S1152. Gene #102: 'KRT13 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
KRT13 MUTATED	3	1	0
KRT13 WILD-TYPE	235	190	228

'KRT13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S1153. Gene #102: 'KRT13 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
KRT13 MUTATED	2	1	1
KRT13 WILD-TYPE	194	190	269

'KRT13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 0.93

Table S1154. Gene #102: 'KRT13 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
KRT13 MUTATED	0	2	0	1
KRT13 WILD-TYPE	140	105	83	181

'KRT13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0519 (Fisher's exact test), Q value = 0.41

Table S1155. Gene #102: 'KRT13 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
KRT13 MUTATED	0	1	2
KRT13 WILD-TYPE	223	185	101

'KRT13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S1156. Gene #102: 'KRT13 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
KRT13 MUTATED	0	2	0	1
KRT13 WILD-TYPE	127	117	106	155

'KRT13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.649 (Fisher's exact test), Q value = 1

Table S1157. Gene #102: 'KRT13 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
KRT13 MUTATED	0	1	1	0	1	0
KRT13 WILD-TYPE	99	76	119	57	62	92

'MYO5A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.148 (Fisher's exact test), Q value = 0.72

Table S1158. Gene #103: 'MYO5A MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
MYO5A MUTATED	3	1	1
MYO5A WILD-TYPE	289	431	61

'MYO5A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0299 (Fisher's exact test), Q value = 0.3

Table S1159. Gene #103: 'MYO5A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
MYO5A MUTATED	4	0	0	1
MYO5A WILD-TYPE	149	223	88	160

Figure S228. Get High-res Image Gene #103: 'MYO5A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'MYO5A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.47 (Fisher's exact test), Q value = 1

Table S1160. Gene #103: 'MYO5A MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
MYO5A MUTATED	3	0	1	1
MYO5A WILD-TYPE	182	155	137	94

'MYO5A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.186 (Fisher's exact test), Q value = 0.83

Table S1161. Gene #103: 'MYO5A MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
MYO5A MUTATED	4	1	0
MYO5A WILD-TYPE	201	219	148

'MYO5A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 0.85

Table S1162. Gene #103: 'MYO5A MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
MYO5A MUTATED	3	1	0
MYO5A WILD-TYPE	235	190	228

'MYO5A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S1163. Gene #103: 'MYO5A MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
MYO5A MUTATED	2	1	1
MYO5A WILD-TYPE	194	190	269

'MYO5A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S1164. Gene #103: 'MYO5A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
MYO5A MUTATED	2	1	0	1
MYO5A WILD-TYPE	138	106	83	181

'MYO5A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.336 (Fisher's exact test), Q value = 0.98

Table S1165. Gene #103: 'MYO5A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
MYO5A MUTATED	1	1	2
MYO5A WILD-TYPE	222	185	101

'MYO5A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.416 (Fisher's exact test), Q value = 1

Table S1166. Gene #103: 'MYO5A MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
MYO5A MUTATED	2	0	0	2
MYO5A WILD-TYPE	125	119	106	154

'MYO5A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.385 (Fisher's exact test), Q value = 1

Table S1167. Gene #103: 'MYO5A MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
MYO5A MUTATED	1	0	0	0	1	2
MYO5A WILD-TYPE	98	77	120	57	62	90

'MORN5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S1168. Gene #104: 'MORN5 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
MORN5 MUTATED	2	1	0
MORN5 WILD-TYPE	290	431	62

'MORN5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S1169. Gene #104: 'MORN5 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
MORN5 MUTATED	0	1	1	1
MORN5 WILD-TYPE	185	154	137	94

'MORN5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.48 (Fisher's exact test), Q value = 1

Table S1170. Gene #104: 'MORN5 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
MORN5 MUTATED	0	2	1
MORN5 WILD-TYPE	205	218	147

'KRT3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.749 (Fisher's exact test), Q value = 1

Table S1171. Gene #105: 'KRT3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
KRT3 MUTATED	1	3	0
KRT3 WILD-TYPE	291	429	62

'KRT3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1172. Gene #105: 'KRT3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
KRT3 MUTATED	1	2	0	1
KRT3 WILD-TYPE	152	221	88	160

'KRT3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 0.94

Table S1173. Gene #105: 'KRT3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
KRT3 MUTATED	2	0	0	1
KRT3 WILD-TYPE	183	155	138	94

'KRT3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S1174. Gene #105: 'KRT3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
KRT3 MUTATED	2	1	0
KRT3 WILD-TYPE	203	219	148

'KRT3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.272 (Fisher's exact test), Q value = 0.91

Table S1175. Gene #105: 'KRT3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
KRT3 MUTATED	1	0	3
KRT3 WILD-TYPE	237	191	225

'KRT3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S1176. Gene #105: 'KRT3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
KRT3 MUTATED	1	2	1
KRT3 WILD-TYPE	195	189	269

'KRT3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.336 (Fisher's exact test), Q value = 0.98

Table S1177. Gene #105: 'KRT3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
KRT3 MUTATED	2	1	1	0
KRT3 WILD-TYPE	138	106	82	182

'KRT3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.195 (Fisher's exact test), Q value = 0.83

Table S1178. Gene #105: 'KRT3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
KRT3 MUTATED	2	0	2
KRT3 WILD-TYPE	221	186	101

'KRT3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 0.63

Table S1179. Gene #105: 'KRT3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
KRT3 MUTATED	3	1	0	0
KRT3 WILD-TYPE	124	118	106	156

'KRT3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.425 (Fisher's exact test), Q value = 1

Table S1180. Gene #105: 'KRT3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
KRT3 MUTATED	2	0	0	0	1	1
KRT3 WILD-TYPE	97	77	120	57	62	91

'LGALS13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S1181. Gene #106: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
LGALS13 MUTATED	1	2	1
LGALS13 WILD-TYPE	291	430	61

'LGALS13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0464 (Fisher's exact test), Q value = 0.4

Table S1182. Gene #106: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
LGALS13 MUTATED	0	0	2	1
LGALS13 WILD-TYPE	153	223	86	160

Figure S229. Get High-res Image Gene #106: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'LGALS13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1183. Gene #106: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
LGALS13 MUTATED	1	1	1
LGALS13 WILD-TYPE	237	190	227

'LGALS13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.788 (Fisher's exact test), Q value = 1

Table S1184. Gene #106: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
LGALS13 MUTATED	1	0	2
LGALS13 WILD-TYPE	195	191	268

'LGALS13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0491 (Fisher's exact test), Q value = 0.41

Table S1185. Gene #106: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
LGALS13 MUTATED	3	0	0	0
LGALS13 WILD-TYPE	137	107	83	182

Figure S230. Get High-res Image Gene #106: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'LGALS13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.315 (Fisher's exact test), Q value = 0.94

Table S1186. Gene #106: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
LGALS13 MUTATED	3	0	0
LGALS13 WILD-TYPE	220	186	103

'LGALS13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.286 (Fisher's exact test), Q value = 0.93

Table S1187. Gene #106: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
LGALS13 MUTATED	1	2	0	0
LGALS13 WILD-TYPE	126	117	106	156

'LGALS13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.169 (Fisher's exact test), Q value = 0.79

Table S1188. Gene #106: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
LGALS13 MUTATED	0	1	0	1	1	0
LGALS13 WILD-TYPE	99	76	120	56	62	92

'CD44 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S1189. Gene #107: 'CD44 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
CD44 MUTATED	2	0	1	0
CD44 WILD-TYPE	76	41	63	57

'CD44 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.266 (Fisher's exact test), Q value = 0.91

Table S1190. Gene #107: 'CD44 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
CD44 MUTATED	2	0	1	0
CD44 WILD-TYPE	61	50	47	79

'CD44 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.337 (Fisher's exact test), Q value = 0.98

Table S1191. Gene #107: 'CD44 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
CD44 MUTATED	0	1	0	2
CD44 WILD-TYPE	70	97	44	61

'CD44 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S1192. Gene #107: 'CD44 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
CD44 MUTATED	1	1	1
CD44 WILD-TYPE	137	60	75

'CD44 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.421 (Fisher's exact test), Q value = 1

Table S1193. Gene #107: 'CD44 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
CD44 MUTATED	4	2	0
CD44 WILD-TYPE	288	430	62

'CD44 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1194. Gene #107: 'CD44 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
CD44 MUTATED	1	1	0	1
CD44 WILD-TYPE	152	222	88	160

'CD44 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0532 (Fisher's exact test), Q value = 0.42

Table S1195. Gene #107: 'CD44 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
CD44 MUTATED	4	0	0	0
CD44 WILD-TYPE	181	155	138	95

'CD44 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S1196. Gene #107: 'CD44 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
CD44 MUTATED	2	2	0
CD44 WILD-TYPE	203	218	148

'CD44 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.293 (Fisher's exact test), Q value = 0.93

Table S1197. Gene #107: 'CD44 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
CD44 MUTATED	1	2	0
CD44 WILD-TYPE	237	189	228

'CD44 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S1198. Gene #107: 'CD44 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
CD44 MUTATED	0	1	2
CD44 WILD-TYPE	196	190	268

'CD44 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S1199. Gene #107: 'CD44 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
CD44 MUTATED	0	1	0	2
CD44 WILD-TYPE	140	106	83	180

'CD44 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.233 (Fisher's exact test), Q value = 0.89

Table S1200. Gene #107: 'CD44 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
CD44 MUTATED	0	2	1
CD44 WILD-TYPE	223	184	102

'CD44 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.561 (Fisher's exact test), Q value = 1

Table S1201. Gene #107: 'CD44 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
CD44 MUTATED	0	1	0	2
CD44 WILD-TYPE	127	118	106	154

'CD44 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S1202. Gene #107: 'CD44 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
CD44 MUTATED	0	1	1	0	0	1
CD44 WILD-TYPE	99	76	119	57	63	91

'GRHL3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.912 (Fisher's exact test), Q value = 1

Table S1203. Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
GRHL3 MUTATED	2	0	1	1
GRHL3 WILD-TYPE	76	41	63	56

'GRHL3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1204. Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
GRHL3 MUTATED	1	1	1	1
GRHL3 WILD-TYPE	62	49	47	78

'GRHL3 MUTATION STATUS' versus 'MIR_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1205. Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
GRHL3 MUTATED	1	2	0	1
GRHL3 WILD-TYPE	69	96	44	62

'GRHL3 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S1206. Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
GRHL3 MUTATED	1	1	2
GRHL3 WILD-TYPE	137	60	74

'GRHL3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0394 (Fisher's exact test), Q value = 0.36

Table S1207. Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
GRHL3 MUTATED	6	1	0
GRHL3 WILD-TYPE	286	431	62

Figure S231. Get High-res Image Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'GRHL3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0863 (Fisher's exact test), Q value = 0.54

Table S1208. Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
GRHL3 MUTATED	4	1	1	0
GRHL3 WILD-TYPE	149	222	87	161

'GRHL3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.931 (Fisher's exact test), Q value = 1

Table S1209. Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
GRHL3 MUTATED	1	2	1	1
GRHL3 WILD-TYPE	184	153	137	94

'GRHL3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.643 (Fisher's exact test), Q value = 1

Table S1210. Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
GRHL3 MUTATED	2	1	2
GRHL3 WILD-TYPE	203	219	146

'GRHL3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0321 (Fisher's exact test), Q value = 0.31

Table S1211. Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
GRHL3 MUTATED	5	1	0
GRHL3 WILD-TYPE	233	190	228

Figure S232. Get High-res Image Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'GRHL3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S1212. Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
GRHL3 MUTATED	3	2	1
GRHL3 WILD-TYPE	193	189	269

'GRHL3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.541 (Fisher's exact test), Q value = 1

Table S1213. Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
GRHL3 MUTATED	1	2	0	1
GRHL3 WILD-TYPE	139	105	83	181

'GRHL3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0132 (Fisher's exact test), Q value = 0.18

Table S1214. Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
GRHL3 MUTATED	0	1	3
GRHL3 WILD-TYPE	223	185	100

Figure S233. Get High-res Image Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'GRHL3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.287 (Fisher's exact test), Q value = 0.93

Table S1215. Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
GRHL3 MUTATED	1	0	0	3
GRHL3 WILD-TYPE	126	119	106	153

'GRHL3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.297 (Fisher's exact test), Q value = 0.94

Table S1216. Gene #108: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
GRHL3 MUTATED	0	0	1	0	2	1
GRHL3 WILD-TYPE	99	77	119	57	61	91

'CD1D MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S1217. Gene #109: 'CD1D MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
CD1D MUTATED	1	1	1	0
CD1D WILD-TYPE	77	40	63	57

'CD1D MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1218. Gene #109: 'CD1D MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
CD1D MUTATED	1	1	0	1
CD1D WILD-TYPE	62	49	48	78

'CD1D MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S1219. Gene #109: 'CD1D MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
CD1D MUTATED	2	2	0	0
CD1D WILD-TYPE	68	96	44	63

'CD1D MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.122 (Fisher's exact test), Q value = 0.66

Table S1220. Gene #109: 'CD1D MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
CD1D MUTATED	1	0	3
CD1D WILD-TYPE	137	61	73

'CD1D MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0686 (Fisher's exact test), Q value = 0.48

Table S1221. Gene #109: 'CD1D MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
CD1D MUTATED	4	0	0
CD1D WILD-TYPE	288	432	62

'CD1D MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 0.63

Table S1222. Gene #109: 'CD1D MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
CD1D MUTATED	2	0	1	0
CD1D WILD-TYPE	151	223	87	161

'CD1D MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S1223. Gene #109: 'CD1D MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
CD1D MUTATED	2	0	1	0
CD1D WILD-TYPE	183	155	137	95

'CD1D MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S1224. Gene #109: 'CD1D MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
CD1D MUTATED	1	2	0
CD1D WILD-TYPE	204	218	148

'CNOT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S1225. Gene #110: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
CNOT1 MUTATED	2	6	0
CNOT1 WILD-TYPE	290	426	62

'CNOT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.954 (Fisher's exact test), Q value = 1

Table S1226. Gene #110: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
CNOT1 MUTATED	1	3	1	2
CNOT1 WILD-TYPE	152	220	87	159

'CNOT1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.525 (Fisher's exact test), Q value = 1

Table S1227. Gene #110: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
CNOT1 MUTATED	4	2	1	0
CNOT1 WILD-TYPE	181	153	137	95

'CNOT1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1228. Gene #110: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
CNOT1 MUTATED	2	3	2
CNOT1 WILD-TYPE	203	217	146

'CNOT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S1229. Gene #110: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
CNOT1 MUTATED	3	3	2
CNOT1 WILD-TYPE	235	188	226

'CNOT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0471 (Fisher's exact test), Q value = 0.4

Table S1230. Gene #110: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
CNOT1 MUTATED	0	5	3
CNOT1 WILD-TYPE	196	186	267

Figure S234. Get High-res Image Gene #110: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'CNOT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.771 (Fisher's exact test), Q value = 1

Table S1231. Gene #110: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
CNOT1 MUTATED	2	2	0	3
CNOT1 WILD-TYPE	138	105	83	179

'CNOT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.694 (Fisher's exact test), Q value = 1

Table S1232. Gene #110: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
CNOT1 MUTATED	2	3	2
CNOT1 WILD-TYPE	221	183	101

'CNOT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.389 (Fisher's exact test), Q value = 1

Table S1233. Gene #110: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
CNOT1 MUTATED	1	3	0	3
CNOT1 WILD-TYPE	126	116	106	153

'CNOT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.411 (Fisher's exact test), Q value = 1

Table S1234. Gene #110: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
CNOT1 MUTATED	1	3	1	0	0	2
CNOT1 WILD-TYPE	98	74	119	57	63	90

'NAP1L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1235. Gene #111: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
NAP1L2 MUTATED	2	4	0
NAP1L2 WILD-TYPE	290	428	62

'NAP1L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.582 (Fisher's exact test), Q value = 1

Table S1236. Gene #111: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
NAP1L2 MUTATED	0	2	0	2
NAP1L2 WILD-TYPE	153	221	88	159

'NAP1L2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1237. Gene #111: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
NAP1L2 MUTATED	1	1	1	1
NAP1L2 WILD-TYPE	184	154	137	94

'NAP1L2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 0.9

Table S1238. Gene #111: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
NAP1L2 MUTATED	0	3	1
NAP1L2 WILD-TYPE	205	217	147

'NAP1L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.743 (Fisher's exact test), Q value = 1

Table S1239. Gene #111: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
NAP1L2 MUTATED	1	2	2
NAP1L2 WILD-TYPE	237	189	226

'NAP1L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.87 (Fisher's exact test), Q value = 1

Table S1240. Gene #111: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
NAP1L2 MUTATED	1	2	2
NAP1L2 WILD-TYPE	195	189	268

'NAP1L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1241. Gene #111: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
NAP1L2 MUTATED	1	1	0	2
NAP1L2 WILD-TYPE	139	106	83	180

'NAP1L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.833 (Fisher's exact test), Q value = 1

Table S1242. Gene #111: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
NAP1L2 MUTATED	2	2	0
NAP1L2 WILD-TYPE	221	184	103

'NAP1L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.621 (Fisher's exact test), Q value = 1

Table S1243. Gene #111: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
NAP1L2 MUTATED	2	0	1	1
NAP1L2 WILD-TYPE	125	119	105	155

'NAP1L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S1244. Gene #111: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
NAP1L2 MUTATED	2	0	1	0	0	1
NAP1L2 WILD-TYPE	97	77	119	57	63	91

'OR52M1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.649 (Fisher's exact test), Q value = 1

Table S1245. Gene #112: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
OR52M1 MUTATED	2	1	0	1
OR52M1 WILD-TYPE	76	40	64	56

'OR52M1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S1246. Gene #112: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
OR52M1 MUTATED	1	2	0	1
OR52M1 WILD-TYPE	62	48	48	78

'OR52M1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 0.64

Table S1247. Gene #112: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
OR52M1 MUTATED	0	1	0	3
OR52M1 WILD-TYPE	70	97	44	60

'OR52M1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.0593 (Fisher's exact test), Q value = 0.45

Table S1248. Gene #112: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
OR52M1 MUTATED	1	3	0
OR52M1 WILD-TYPE	137	58	76

'OR52M1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.14 (Fisher's exact test), Q value = 0.71

Table S1249. Gene #112: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
OR52M1 MUTATED	5	2	1
OR52M1 WILD-TYPE	287	430	61

'OR52M1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.546 (Fisher's exact test), Q value = 1

Table S1250. Gene #112: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
OR52M1 MUTATED	2	2	1	0
OR52M1 WILD-TYPE	151	221	87	161

'OR52M1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.505 (Fisher's exact test), Q value = 1

Table S1251. Gene #112: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
OR52M1 MUTATED	2	1	3	0
OR52M1 WILD-TYPE	183	154	135	95

'OR52M1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.772 (Fisher's exact test), Q value = 1

Table S1252. Gene #112: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
OR52M1 MUTATED	3	2	1
OR52M1 WILD-TYPE	202	218	147

'OR52M1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.239 (Fisher's exact test), Q value = 0.89

Table S1253. Gene #112: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
OR52M1 MUTATED	5	1	1
OR52M1 WILD-TYPE	233	190	227

'OR52M1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.27 (Fisher's exact test), Q value = 0.91

Table S1254. Gene #112: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
OR52M1 MUTATED	4	2	1
OR52M1 WILD-TYPE	192	189	269

'OR52M1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S1255. Gene #112: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
OR52M1 MUTATED	2	1	0	1
OR52M1 WILD-TYPE	138	106	83	181

'OR52M1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1256. Gene #112: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
OR52M1 MUTATED	2	1	1
OR52M1 WILD-TYPE	221	185	102

'OR52M1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.673 (Fisher's exact test), Q value = 1

Table S1257. Gene #112: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
OR52M1 MUTATED	1	2	0	1
OR52M1 WILD-TYPE	126	117	106	155

'OR52M1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.897 (Fisher's exact test), Q value = 1

Table S1258. Gene #112: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
OR52M1 MUTATED	1	1	1	0	1	0
OR52M1 WILD-TYPE	98	76	119	57	62	92

'OAS2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1259. Gene #113: 'OAS2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
OAS2 MUTATED	1	0	1	1
OAS2 WILD-TYPE	77	41	63	56

'OAS2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.699 (Fisher's exact test), Q value = 1

Table S1260. Gene #113: 'OAS2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
OAS2 MUTATED	0	1	1	1
OAS2 WILD-TYPE	63	49	47	78

'OAS2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.686 (Fisher's exact test), Q value = 1

Table S1261. Gene #113: 'OAS2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
OAS2 MUTATED	0	2	0	1
OAS2 WILD-TYPE	70	96	44	62

'OAS2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S1262. Gene #113: 'OAS2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
OAS2 MUTATED	1	1	1
OAS2 WILD-TYPE	137	60	75

'OAS2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.502 (Fisher's exact test), Q value = 1

Table S1263. Gene #113: 'OAS2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
OAS2 MUTATED	3	1	0
OAS2 WILD-TYPE	289	431	62

'OAS2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S1264. Gene #113: 'OAS2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
OAS2 MUTATED	3	0	1
OAS2 WILD-TYPE	235	191	227

'OAS2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.104 (Fisher's exact test), Q value = 0.61

Table S1265. Gene #113: 'OAS2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
OAS2 MUTATED	3	1	0
OAS2 WILD-TYPE	193	190	270

'FMR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S1266. Gene #114: 'FMR1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
FMR1 MUTATED	1	4	0
FMR1 WILD-TYPE	291	428	62

'FMR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 0.91

Table S1267. Gene #114: 'FMR1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
FMR1 MUTATED	1	2	2	0
FMR1 WILD-TYPE	152	221	86	161

'FMR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.596 (Fisher's exact test), Q value = 1

Table S1268. Gene #114: 'FMR1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
FMR1 MUTATED	1	1	1	2
FMR1 WILD-TYPE	184	154	137	93

'FMR1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1269. Gene #114: 'FMR1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
FMR1 MUTATED	2	2	1
FMR1 WILD-TYPE	203	218	147

'FMR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.389 (Fisher's exact test), Q value = 1

Table S1270. Gene #114: 'FMR1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
FMR1 MUTATED	3	0	2
FMR1 WILD-TYPE	235	191	226

'FMR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00194 (Fisher's exact test), Q value = 0.043

Table S1271. Gene #114: 'FMR1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
FMR1 MUTATED	0	5	0
FMR1 WILD-TYPE	196	186	270

Figure S235. Get High-res Image Gene #114: 'FMR1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'FMR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.24 (Fisher's exact test), Q value = 0.89

Table S1272. Gene #114: 'FMR1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
FMR1 MUTATED	1	3	0	1
FMR1 WILD-TYPE	139	104	83	181

'FMR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.358 (Fisher's exact test), Q value = 1

Table S1273. Gene #114: 'FMR1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
FMR1 MUTATED	1	2	2
FMR1 WILD-TYPE	222	184	101

'FMR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.733 (Fisher's exact test), Q value = 1

Table S1274. Gene #114: 'FMR1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
FMR1 MUTATED	1	2	0	2
FMR1 WILD-TYPE	126	117	106	154

'FMR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.313 (Fisher's exact test), Q value = 0.94

Table S1275. Gene #114: 'FMR1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
FMR1 MUTATED	1	2	0	0	0	2
FMR1 WILD-TYPE	98	75	120	57	63	90

'INF2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1276. Gene #115: 'INF2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
INF2 MUTATED	2	2	0
INF2 WILD-TYPE	290	430	62

'INF2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1277. Gene #115: 'INF2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
INF2 MUTATED	1	1	0	1
INF2 WILD-TYPE	152	222	88	160

'INF2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.702 (Fisher's exact test), Q value = 1

Table S1278. Gene #115: 'INF2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
INF2 MUTATED	1	0	1	1
INF2 WILD-TYPE	184	155	137	94

'INF2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1279. Gene #115: 'INF2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
INF2 MUTATED	1	1	1
INF2 WILD-TYPE	204	219	147

'INF2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S1280. Gene #115: 'INF2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
INF2 MUTATED	2	1	0
INF2 WILD-TYPE	236	190	228

'INF2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1281. Gene #115: 'INF2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
INF2 MUTATED	1	1	1
INF2 WILD-TYPE	195	190	269

'INF2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1282. Gene #115: 'INF2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
INF2 MUTATED	1	1	0	1
INF2 WILD-TYPE	139	106	83	181

'INF2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0522 (Fisher's exact test), Q value = 0.41

Table S1283. Gene #115: 'INF2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
INF2 MUTATED	0	1	2
INF2 WILD-TYPE	223	185	101

'INF2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1284. Gene #115: 'INF2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
INF2 MUTATED	1	1	0	1
INF2 WILD-TYPE	126	118	106	155

'INF2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.646 (Fisher's exact test), Q value = 1

Table S1285. Gene #115: 'INF2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
INF2 MUTATED	0	1	1	0	1	0
INF2 WILD-TYPE	99	76	119	57	62	92

'EPS8L1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.502 (Fisher's exact test), Q value = 1

Table S1286. Gene #116: 'EPS8L1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
EPS8L1 MUTATED	3	1	0
EPS8L1 WILD-TYPE	289	431	62

'EPS8L1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S1287. Gene #116: 'EPS8L1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
EPS8L1 MUTATED	2	1	0	0
EPS8L1 WILD-TYPE	151	222	88	161

'EPS8L1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.166 (Fisher's exact test), Q value = 0.78

Table S1288. Gene #116: 'EPS8L1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
EPS8L1 MUTATED	3	0	0	0
EPS8L1 WILD-TYPE	182	155	138	95

'EPS8L1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0622 (Fisher's exact test), Q value = 0.46

Table S1289. Gene #116: 'EPS8L1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
EPS8L1 MUTATED	3	0	0
EPS8L1 WILD-TYPE	202	220	148

'EPS8L1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S1290. Gene #116: 'EPS8L1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
EPS8L1 MUTATED	2	1	0
EPS8L1 WILD-TYPE	236	190	228

'EPS8L1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1291. Gene #116: 'EPS8L1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
EPS8L1 MUTATED	1	1	1
EPS8L1 WILD-TYPE	195	190	269

'CD209 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.832 (Fisher's exact test), Q value = 1

Table S1292. Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
CD209 MUTATED	1	0	2	1
CD209 WILD-TYPE	77	41	62	56

'CD209 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1293. Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
CD209 MUTATED	1	1	1	1
CD209 WILD-TYPE	62	49	47	78

'CD209 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.327 (Fisher's exact test), Q value = 0.97

Table S1294. Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
CD209 MUTATED	1	1	0	3
CD209 WILD-TYPE	69	97	44	60

'CD209 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.609 (Fisher's exact test), Q value = 1

Table S1295. Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
CD209 MUTATED	3	0	2
CD209 WILD-TYPE	135	61	74

'CD209 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0865 (Fisher's exact test), Q value = 0.54

Table S1296. Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
CD209 MUTATED	6	2	1
CD209 WILD-TYPE	286	430	61

'CD209 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.102 (Fisher's exact test), Q value = 0.6

Table S1297. Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
CD209 MUTATED	4	2	2	0
CD209 WILD-TYPE	149	221	86	161

'CD209 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.031 (Fisher's exact test), Q value = 0.3

Table S1298. Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
CD209 MUTATED	4	0	5	0
CD209 WILD-TYPE	181	155	133	95

Figure S236. Get High-res Image Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'CD209 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.319 (Fisher's exact test), Q value = 0.95

Table S1299. Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
CD209 MUTATED	2	6	1
CD209 WILD-TYPE	203	214	147

'CD209 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 0.71

Table S1300. Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
CD209 MUTATED	5	0	2
CD209 WILD-TYPE	233	191	226

'CD209 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0165 (Fisher's exact test), Q value = 0.2

Table S1301. Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
CD209 MUTATED	5	2	0
CD209 WILD-TYPE	191	189	270

Figure S237. Get High-res Image Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'CD209 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.208 (Fisher's exact test), Q value = 0.85

Table S1302. Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
CD209 MUTATED	2	2	1	0
CD209 WILD-TYPE	138	105	82	182

'CD209 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.116 (Fisher's exact test), Q value = 0.64

Table S1303. Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
CD209 MUTATED	1	1	3
CD209 WILD-TYPE	222	185	100

'CD209 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S1304. Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
CD209 MUTATED	1	2	1	0
CD209 WILD-TYPE	126	117	105	156

'CD209 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00301 (Fisher's exact test), Q value = 0.063

Table S1305. Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
CD209 MUTATED	0	0	0	1	3	0
CD209 WILD-TYPE	99	77	120	56	60	92

Figure S238. Get High-res Image Gene #117: 'CD209 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'TNFRSF9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.391 (Fisher's exact test), Q value = 1

Table S1306. Gene #118: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TNFRSF9 MUTATED	1	2	1
TNFRSF9 WILD-TYPE	291	430	61

'TNFRSF9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.003 (Fisher's exact test), Q value = 0.063

Table S1307. Gene #118: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TNFRSF9 MUTATED	1	0	3	0
TNFRSF9 WILD-TYPE	152	223	85	161

Figure S239. Get High-res Image Gene #118: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'TNFRSF9 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1308. Gene #118: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TNFRSF9 MUTATED	1	1	1	1
TNFRSF9 WILD-TYPE	184	154	137	94

'TNFRSF9 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.569 (Fisher's exact test), Q value = 1

Table S1309. Gene #118: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TNFRSF9 MUTATED	1	1	2
TNFRSF9 WILD-TYPE	204	219	146

'TNFRSF9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1310. Gene #118: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
TNFRSF9 MUTATED	1	1	1
TNFRSF9 WILD-TYPE	237	190	227

'TNFRSF9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1311. Gene #118: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
TNFRSF9 MUTATED	1	1	1
TNFRSF9 WILD-TYPE	195	190	269

'TNFRSF9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.679 (Fisher's exact test), Q value = 1

Table S1312. Gene #118: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
TNFRSF9 MUTATED	2	0	0	1
TNFRSF9 WILD-TYPE	138	107	83	181

'TNFRSF9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S1313. Gene #118: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
TNFRSF9 MUTATED	1	1	1
TNFRSF9 WILD-TYPE	222	185	102

'TNFRSF9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S1314. Gene #118: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
TNFRSF9 MUTATED	2	0	0	1
TNFRSF9 WILD-TYPE	125	119	106	155

'TNFRSF9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.867 (Fisher's exact test), Q value = 1

Table S1315. Gene #118: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
TNFRSF9 MUTATED	1	0	1	0	1	0
TNFRSF9 WILD-TYPE	98	77	119	57	62	92

'PRG4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.391 (Fisher's exact test), Q value = 1

Table S1316. Gene #119: 'PRG4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PRG4 MUTATED	2	8	0
PRG4 WILD-TYPE	290	424	62

'PRG4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1317. Gene #119: 'PRG4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
PRG4 MUTATED	2	4	1	3
PRG4 WILD-TYPE	151	219	87	158

'PRG4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 0.98

Table S1318. Gene #119: 'PRG4 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PRG4 MUTATED	3	3	0	2
PRG4 WILD-TYPE	182	152	138	93

'PRG4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S1319. Gene #119: 'PRG4 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PRG4 MUTATED	1	4	3
PRG4 WILD-TYPE	204	216	145

'PRG4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S1320. Gene #119: 'PRG4 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
PRG4 MUTATED	2	4	3
PRG4 WILD-TYPE	236	187	225

'PRG4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.196 (Fisher's exact test), Q value = 0.83

Table S1321. Gene #119: 'PRG4 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
PRG4 MUTATED	1	5	3
PRG4 WILD-TYPE	195	186	267

'PRG4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.415 (Fisher's exact test), Q value = 1

Table S1322. Gene #119: 'PRG4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
PRG4 MUTATED	4	2	0	2
PRG4 WILD-TYPE	136	105	83	180

'PRG4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S1323. Gene #119: 'PRG4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
PRG4 MUTATED	3	3	2
PRG4 WILD-TYPE	220	183	101

'PRG4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S1324. Gene #119: 'PRG4 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
PRG4 MUTATED	2	2	1	3
PRG4 WILD-TYPE	125	117	105	153

'PRG4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S1325. Gene #119: 'PRG4 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
PRG4 MUTATED	2	1	2	1	2	0
PRG4 WILD-TYPE	97	76	118	56	61	92

'RFX4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.527 (Fisher's exact test), Q value = 1

Table S1326. Gene #120: 'RFX4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
RFX4 MUTATED	2	3	1
RFX4 WILD-TYPE	290	429	61

'RFX4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.206 (Fisher's exact test), Q value = 0.84

Table S1327. Gene #120: 'RFX4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
RFX4 MUTATED	2	0	1	2
RFX4 WILD-TYPE	151	223	87	159

'RFX4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S1328. Gene #120: 'RFX4 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
RFX4 MUTATED	3	1	0	0
RFX4 WILD-TYPE	182	154	138	95

'RFX4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S1329. Gene #120: 'RFX4 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
RFX4 MUTATED	2	1	1
RFX4 WILD-TYPE	203	219	147

'RFX4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S1330. Gene #120: 'RFX4 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
RFX4 MUTATED	1	1	2
RFX4 WILD-TYPE	237	190	226

'RFX4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.312 (Fisher's exact test), Q value = 0.94

Table S1331. Gene #120: 'RFX4 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
RFX4 MUTATED	0	1	3
RFX4 WILD-TYPE	196	190	267

'RFX4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S1332. Gene #120: 'RFX4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
RFX4 MUTATED	0	1	1	2
RFX4 WILD-TYPE	140	106	82	180

'RFX4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S1333. Gene #120: 'RFX4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
RFX4 MUTATED	1	2	1
RFX4 WILD-TYPE	222	184	102

'RFX4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.231 (Fisher's exact test), Q value = 0.89

Table S1334. Gene #120: 'RFX4 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
RFX4 MUTATED	0	0	2	2
RFX4 WILD-TYPE	127	119	104	154

'RFX4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.76 (Fisher's exact test), Q value = 1

Table S1335. Gene #120: 'RFX4 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
RFX4 MUTATED	0	1	1	1	0	1
RFX4 WILD-TYPE	99	76	119	56	63	91

'LUM MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.546 (Fisher's exact test), Q value = 1

Table S1336. Gene #121: 'LUM MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
LUM MUTATED	1	0	2	0
LUM WILD-TYPE	77	41	62	57

'LUM MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.116 (Fisher's exact test), Q value = 0.64

Table S1337. Gene #121: 'LUM MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
LUM MUTATED	1	0	2	0
LUM WILD-TYPE	62	50	46	79

'LUM MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.166 (Fisher's exact test), Q value = 0.78

Table S1338. Gene #121: 'LUM MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
LUM MUTATED	0	1	1	3
LUM WILD-TYPE	70	97	43	60

'LUM MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S1339. Gene #121: 'LUM MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
LUM MUTATED	2	2	1
LUM WILD-TYPE	136	59	75

'LUM MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0394 (Fisher's exact test), Q value = 0.36

Table S1340. Gene #121: 'LUM MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
LUM MUTATED	6	1	0
LUM WILD-TYPE	286	431	62

Figure S240. Get High-res Image Gene #121: 'LUM MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'LUM MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S1341. Gene #121: 'LUM MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
LUM MUTATED	2	1	1	0
LUM WILD-TYPE	151	222	87	161

'LUM MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1342. Gene #121: 'LUM MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
LUM MUTATED	1	1	1	1
LUM WILD-TYPE	184	154	137	94

'LUM MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1343. Gene #121: 'LUM MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
LUM MUTATED	1	2	1
LUM WILD-TYPE	204	218	147

'LUM MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S1344. Gene #121: 'LUM MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
LUM MUTATED	2	1	0
LUM WILD-TYPE	236	190	228

'LUM MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1345. Gene #121: 'LUM MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
LUM MUTATED	1	1	1
LUM WILD-TYPE	195	190	269

'MYT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.641 (Fisher's exact test), Q value = 1

Table S1346. Gene #122: 'MYT1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
MYT1 MUTATED	1	5	0
MYT1 WILD-TYPE	291	427	62

'MYT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.22 (Fisher's exact test), Q value = 0.87

Table S1347. Gene #122: 'MYT1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
MYT1 MUTATED	1	3	2	0
MYT1 WILD-TYPE	152	220	86	161

'MYT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S1348. Gene #122: 'MYT1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
MYT1 MUTATED	2	1	3
MYT1 WILD-TYPE	236	190	225

'MYT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0183 (Fisher's exact test), Q value = 0.21

Table S1349. Gene #122: 'MYT1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
MYT1 MUTATED	0	5	1
MYT1 WILD-TYPE	196	186	269

Figure S241. Get High-res Image Gene #122: 'MYT1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'MYT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.41 (Fisher's exact test), Q value = 1

Table S1350. Gene #122: 'MYT1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
MYT1 MUTATED	0	2	1	3
MYT1 WILD-TYPE	140	105	82	179

'MYT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.757 (Fisher's exact test), Q value = 1

Table S1351. Gene #122: 'MYT1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
MYT1 MUTATED	2	2	2
MYT1 WILD-TYPE	221	184	101

'MYT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S1352. Gene #122: 'MYT1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
MYT1 MUTATED	1	1	1	3
MYT1 WILD-TYPE	126	118	105	153

'MYT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.95 (Fisher's exact test), Q value = 1

Table S1353. Gene #122: 'MYT1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
MYT1 MUTATED	2	1	2	0	0	1
MYT1 WILD-TYPE	97	76	118	57	63	91

'KCNJ15 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.746 (Fisher's exact test), Q value = 1

Table S1354. Gene #123: 'KCNJ15 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
KCNJ15 MUTATED	1	3	0
KCNJ15 WILD-TYPE	291	429	62

'KCNJ15 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.866 (Fisher's exact test), Q value = 1

Table S1355. Gene #123: 'KCNJ15 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
KCNJ15 MUTATED	0	2	0	1
KCNJ15 WILD-TYPE	153	221	88	160

'KCNJ15 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 1

Table S1356. Gene #123: 'KCNJ15 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
KCNJ15 MUTATED	1	2	1
KCNJ15 WILD-TYPE	237	189	227

'KCNJ15 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1357. Gene #123: 'KCNJ15 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
KCNJ15 MUTATED	1	1	2
KCNJ15 WILD-TYPE	195	190	268

'KCNJ15 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.237 (Fisher's exact test), Q value = 0.89

Table S1358. Gene #123: 'KCNJ15 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
KCNJ15 MUTATED	0	0	0	3
KCNJ15 WILD-TYPE	140	107	83	179

'KCNJ15 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.101 (Fisher's exact test), Q value = 0.6

Table S1359. Gene #123: 'KCNJ15 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
KCNJ15 MUTATED	0	3	0
KCNJ15 WILD-TYPE	223	183	103

'KCNJ15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0639 (Fisher's exact test), Q value = 0.46

Table S1360. Gene #123: 'KCNJ15 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
KCNJ15 MUTATED	0	0	0	3
KCNJ15 WILD-TYPE	127	119	106	153

'KCNJ15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.705 (Fisher's exact test), Q value = 1

Table S1361. Gene #123: 'KCNJ15 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
KCNJ15 MUTATED	0	0	2	0	0	1
KCNJ15 WILD-TYPE	99	77	118	57	63	91

'GFRA4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S1362. Gene #124: 'GFRA4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
GFRA4 MUTATED	2	1	0
GFRA4 WILD-TYPE	290	431	62

'GFRA4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S1363. Gene #124: 'GFRA4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
GFRA4 MUTATED	2	1	0	0
GFRA4 WILD-TYPE	151	222	88	161

'DLC1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1364. Gene #125: 'DLC1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
DLC1 MUTATED	1	0	1	1
DLC1 WILD-TYPE	77	41	63	56

'DLC1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0589 (Fisher's exact test), Q value = 0.45

Table S1365. Gene #125: 'DLC1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
DLC1 MUTATED	0	1	2	0
DLC1 WILD-TYPE	63	49	46	79

'DLC1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S1366. Gene #125: 'DLC1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
DLC1 MUTATED	1	0	1	1
DLC1 WILD-TYPE	69	98	43	62

'DLC1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.194 (Fisher's exact test), Q value = 0.83

Table S1367. Gene #125: 'DLC1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
DLC1 MUTATED	1	2	0
DLC1 WILD-TYPE	137	59	76

'DLC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 0.64

Table S1368. Gene #125: 'DLC1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
DLC1 MUTATED	6	2	0
DLC1 WILD-TYPE	286	430	62

'DLC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.317 (Fisher's exact test), Q value = 0.95

Table S1369. Gene #125: 'DLC1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
DLC1 MUTATED	4	2	0	1
DLC1 WILD-TYPE	149	221	88	160

'DLC1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S1370. Gene #125: 'DLC1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
DLC1 MUTATED	2	1	2	2
DLC1 WILD-TYPE	183	154	136	93

'DLC1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1371. Gene #125: 'DLC1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
DLC1 MUTATED	2	3	2
DLC1 WILD-TYPE	203	217	146

'DLC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S1372. Gene #125: 'DLC1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
DLC1 MUTATED	5	1	2
DLC1 WILD-TYPE	233	190	226

'DLC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 0.9

Table S1373. Gene #125: 'DLC1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
DLC1 MUTATED	4	3	1
DLC1 WILD-TYPE	192	188	269

'DLC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.891 (Fisher's exact test), Q value = 1

Table S1374. Gene #125: 'DLC1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
DLC1 MUTATED	1	2	1	2
DLC1 WILD-TYPE	139	105	82	180

'DLC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.147 (Fisher's exact test), Q value = 0.72

Table S1375. Gene #125: 'DLC1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
DLC1 MUTATED	1	2	3
DLC1 WILD-TYPE	222	184	100

'DLC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.642 (Fisher's exact test), Q value = 1

Table S1376. Gene #125: 'DLC1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
DLC1 MUTATED	2	1	0	3
DLC1 WILD-TYPE	125	118	106	153

'DLC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00748 (Fisher's exact test), Q value = 0.12

Table S1377. Gene #125: 'DLC1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
DLC1 MUTATED	0	0	0	0	2	4
DLC1 WILD-TYPE	99	77	120	57	61	88

Figure S242. Get High-res Image Gene #125: 'DLC1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'TMPRSS6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.732 (Fisher's exact test), Q value = 1

Table S1378. Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
TMPRSS6 MUTATED	3	0	2	1
TMPRSS6 WILD-TYPE	75	41	62	56

'TMPRSS6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.702 (Fisher's exact test), Q value = 1

Table S1379. Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
TMPRSS6 MUTATED	3	1	1	1
TMPRSS6 WILD-TYPE	60	49	47	78

'TMPRSS6 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.726 (Fisher's exact test), Q value = 1

Table S1380. Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
TMPRSS6 MUTATED	2	1	1	2
TMPRSS6 WILD-TYPE	68	97	43	61

'TMPRSS6 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.264 (Fisher's exact test), Q value = 0.91

Table S1381. Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TMPRSS6 MUTATED	2	3	1
TMPRSS6 WILD-TYPE	136	58	75

'TMPRSS6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00759 (Fisher's exact test), Q value = 0.12

Table S1382. Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TMPRSS6 MUTATED	8	1	0
TMPRSS6 WILD-TYPE	284	431	62

Figure S243. Get High-res Image Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'TMPRSS6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0149 (Fisher's exact test), Q value = 0.19

Table S1383. Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TMPRSS6 MUTATED	5	1	0	0
TMPRSS6 WILD-TYPE	148	222	88	161

Figure S244. Get High-res Image Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'TMPRSS6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S1384. Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TMPRSS6 MUTATED	4	1	2	0
TMPRSS6 WILD-TYPE	181	154	136	95

'TMPRSS6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.116 (Fisher's exact test), Q value = 0.64

Table S1385. Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TMPRSS6 MUTATED	5	2	0
TMPRSS6 WILD-TYPE	200	218	148

'TMPRSS6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00471 (Fisher's exact test), Q value = 0.089

Table S1386. Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
TMPRSS6 MUTATED	8	0	1
TMPRSS6 WILD-TYPE	230	191	227

Figure S245. Get High-res Image Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'TMPRSS6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00726 (Fisher's exact test), Q value = 0.12

Table S1387. Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
TMPRSS6 MUTATED	6	3	0
TMPRSS6 WILD-TYPE	190	188	270

Figure S246. Get High-res Image Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'TMPRSS6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.155 (Fisher's exact test), Q value = 0.74

Table S1388. Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
TMPRSS6 MUTATED	1	2	0	0
TMPRSS6 WILD-TYPE	139	105	83	182

'TMPRSS6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.153 (Fisher's exact test), Q value = 0.73

Table S1389. Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
TMPRSS6 MUTATED	1	0	2
TMPRSS6 WILD-TYPE	222	186	101

'TMPRSS6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.436 (Fisher's exact test), Q value = 1

Table S1390. Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
TMPRSS6 MUTATED	2	0	0	1
TMPRSS6 WILD-TYPE	125	119	106	155

'TMPRSS6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S1391. Gene #126: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
TMPRSS6 MUTATED	1	0	0	0	1	1
TMPRSS6 WILD-TYPE	98	77	120	57	62	91

'DLX6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S1392. Gene #127: 'DLX6 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
DLX6 MUTATED	2	2	1
DLX6 WILD-TYPE	290	430	61

'DLX6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S1393. Gene #127: 'DLX6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
DLX6 MUTATED	1	1	1	1
DLX6 WILD-TYPE	152	222	87	160

'DLX6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S1394. Gene #127: 'DLX6 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
DLX6 MUTATED	2	2	0	1
DLX6 WILD-TYPE	183	153	138	94

'DLX6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1395. Gene #127: 'DLX6 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
DLX6 MUTATED	2	2	1
DLX6 WILD-TYPE	203	218	147

'DLX6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S1396. Gene #127: 'DLX6 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
DLX6 MUTATED	2	2	0
DLX6 WILD-TYPE	236	189	228

'DLX6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1397. Gene #127: 'DLX6 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
DLX6 MUTATED	1	1	2
DLX6 WILD-TYPE	195	190	268

'DLX6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.44 (Fisher's exact test), Q value = 1

Table S1398. Gene #127: 'DLX6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
DLX6 MUTATED	0	1	0	3
DLX6 WILD-TYPE	140	106	83	179

'DLX6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0766 (Fisher's exact test), Q value = 0.5

Table S1399. Gene #127: 'DLX6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
DLX6 MUTATED	0	2	2
DLX6 WILD-TYPE	223	184	101

'DLX6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0259 (Fisher's exact test), Q value = 0.27

Table S1400. Gene #127: 'DLX6 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
DLX6 MUTATED	0	0	0	4
DLX6 WILD-TYPE	127	119	106	152

Figure S247. Get High-res Image Gene #127: 'DLX6 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'DLX6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.449 (Fisher's exact test), Q value = 1

Table S1401. Gene #127: 'DLX6 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
DLX6 MUTATED	0	0	2	0	0	2
DLX6 WILD-TYPE	99	77	118	57	63	90

'MAP3K1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.929 (Fisher's exact test), Q value = 1

Table S1402. Gene #128: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
MAP3K1 MUTATED	1	1	2	1
MAP3K1 WILD-TYPE	77	40	62	56

'MAP3K1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.729 (Fisher's exact test), Q value = 1

Table S1403. Gene #128: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
MAP3K1 MUTATED	1	1	2	1
MAP3K1 WILD-TYPE	62	49	46	78

'MAP3K1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.763 (Fisher's exact test), Q value = 1

Table S1404. Gene #128: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
MAP3K1 MUTATED	1	3	0	2
MAP3K1 WILD-TYPE	69	95	44	61

'MAP3K1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.648 (Fisher's exact test), Q value = 1

Table S1405. Gene #128: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
MAP3K1 MUTATED	2	2	2
MAP3K1 WILD-TYPE	136	59	74

'MAP3K1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0711 (Fisher's exact test), Q value = 0.48

Table S1406. Gene #128: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
MAP3K1 MUTATED	7	2	0
MAP3K1 WILD-TYPE	285	430	62

'MAP3K1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S1407. Gene #128: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
MAP3K1 MUTATED	2	2	0	0
MAP3K1 WILD-TYPE	151	221	88	161

'MAP3K1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 0.87

Table S1408. Gene #128: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
MAP3K1 MUTATED	1	0	3	1
MAP3K1 WILD-TYPE	184	155	135	94

'MAP3K1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.452 (Fisher's exact test), Q value = 1

Table S1409. Gene #128: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
MAP3K1 MUTATED	2	3	0
MAP3K1 WILD-TYPE	203	217	148

'MAP3K1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.017 (Fisher's exact test), Q value = 0.21

Table S1410. Gene #128: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
MAP3K1 MUTATED	6	1	0
MAP3K1 WILD-TYPE	232	190	228

Figure S248. Get High-res Image Gene #128: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'MAP3K1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.269 (Fisher's exact test), Q value = 0.91

Table S1411. Gene #128: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
MAP3K1 MUTATED	4	2	1
MAP3K1 WILD-TYPE	192	189	269

'MAP3K1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 0.93

Table S1412. Gene #128: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
MAP3K1 MUTATED	0	2	0	1
MAP3K1 WILD-TYPE	140	105	83	181

'MAP3K1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0517 (Fisher's exact test), Q value = 0.41

Table S1413. Gene #128: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
MAP3K1 MUTATED	0	1	2
MAP3K1 WILD-TYPE	223	185	101

'MAP3K1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.561 (Fisher's exact test), Q value = 1

Table S1414. Gene #128: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
MAP3K1 MUTATED	0	1	0	2
MAP3K1 WILD-TYPE	127	118	106	154

'MAP3K1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.225 (Fisher's exact test), Q value = 0.88

Table S1415. Gene #128: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
MAP3K1 MUTATED	0	1	0	0	0	2
MAP3K1 WILD-TYPE	99	76	120	57	63	90

'ROBO3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.198 (Fisher's exact test), Q value = 0.83

Table S1416. Gene #129: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ROBO3 MUTATED	0	5	0
ROBO3 WILD-TYPE	292	427	62

'ROBO3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S1417. Gene #129: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ROBO3 MUTATED	0	3	0	2
ROBO3 WILD-TYPE	153	220	88	159

'ROBO3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.83

Table S1418. Gene #129: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ROBO3 MUTATED	3	0	0	1
ROBO3 WILD-TYPE	182	155	138	94

'ROBO3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.46 (Fisher's exact test), Q value = 1

Table S1419. Gene #129: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ROBO3 MUTATED	1	3	0
ROBO3 WILD-TYPE	204	217	148

'ROBO3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 0.89

Table S1420. Gene #129: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
ROBO3 MUTATED	0	2	3
ROBO3 WILD-TYPE	238	189	225

'ROBO3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.341 (Fisher's exact test), Q value = 0.98

Table S1421. Gene #129: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
ROBO3 MUTATED	0	2	3
ROBO3 WILD-TYPE	196	189	267

'ROBO3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1422. Gene #129: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
ROBO3 MUTATED	1	1	1	2
ROBO3 WILD-TYPE	139	106	82	180

'ROBO3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.286 (Fisher's exact test), Q value = 0.93

Table S1423. Gene #129: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
ROBO3 MUTATED	4	1	0
ROBO3 WILD-TYPE	219	185	103

'ROBO3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.93 (Fisher's exact test), Q value = 1

Table S1424. Gene #129: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
ROBO3 MUTATED	2	1	1	1
ROBO3 WILD-TYPE	125	118	105	155

'ROBO3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.963 (Fisher's exact test), Q value = 1

Table S1425. Gene #129: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
ROBO3 MUTATED	1	1	1	1	0	1
ROBO3 WILD-TYPE	98	76	119	56	63	91

'SGOL2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S1426. Gene #130: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
SGOL2 MUTATED	2	0	0	1
SGOL2 WILD-TYPE	76	41	64	56

'SGOL2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S1427. Gene #130: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
SGOL2 MUTATED	1	0	0	2
SGOL2 WILD-TYPE	62	50	48	77

'SGOL2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.392 (Fisher's exact test), Q value = 1

Table S1428. Gene #130: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
SGOL2 MUTATED	1	0	1	1
SGOL2 WILD-TYPE	69	98	43	62

'SGOL2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.604 (Fisher's exact test), Q value = 1

Table S1429. Gene #130: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
SGOL2 MUTATED	2	1	0
SGOL2 WILD-TYPE	136	60	76

'SGOL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1430. Gene #130: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SGOL2 MUTATED	3	5	0
SGOL2 WILD-TYPE	289	427	62

'SGOL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.896 (Fisher's exact test), Q value = 1

Table S1431. Gene #130: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SGOL2 MUTATED	1	3	1	1
SGOL2 WILD-TYPE	152	220	87	160

'SGOL2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0538 (Fisher's exact test), Q value = 0.42

Table S1432. Gene #130: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
SGOL2 MUTATED	4	0	0	0
SGOL2 WILD-TYPE	181	155	138	95

'SGOL2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S1433. Gene #130: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
SGOL2 MUTATED	1	3	0
SGOL2 WILD-TYPE	204	217	148

'SGOL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S1434. Gene #130: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SGOL2 MUTATED	3	1	4
SGOL2 WILD-TYPE	235	190	224

'SGOL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.404 (Fisher's exact test), Q value = 1

Table S1435. Gene #130: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SGOL2 MUTATED	2	4	2
SGOL2 WILD-TYPE	194	187	268

'SGOL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.869 (Fisher's exact test), Q value = 1

Table S1436. Gene #130: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
SGOL2 MUTATED	2	1	1	1
SGOL2 WILD-TYPE	138	106	82	181

'SGOL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S1437. Gene #130: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
SGOL2 MUTATED	3	1	1
SGOL2 WILD-TYPE	220	185	102

'SGOL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.692 (Fisher's exact test), Q value = 1

Table S1438. Gene #130: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
SGOL2 MUTATED	2	0	1	2
SGOL2 WILD-TYPE	125	119	105	154

'SGOL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S1439. Gene #130: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
SGOL2 MUTATED	2	0	1	1	0	1
SGOL2 WILD-TYPE	97	77	119	56	63	91

'HTT MUTATION STATUS' versus 'CN_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S1440. Gene #131: 'HTT MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
HTT MUTATED	1	4	0
HTT WILD-TYPE	291	428	62

'HTT MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0449 (Fisher's exact test), Q value = 0.39

Table S1441. Gene #131: 'HTT MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
HTT MUTATED	1	0	0	4
HTT WILD-TYPE	152	223	88	157

Figure S249. Get High-res Image Gene #131: 'HTT MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'HTT MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S1442. Gene #131: 'HTT MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
HTT MUTATED	2	2	1	0
HTT WILD-TYPE	183	153	137	95

'HTT MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S1443. Gene #131: 'HTT MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
HTT MUTATED	1	2	2
HTT WILD-TYPE	204	218	146

'HTT MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.201 (Fisher's exact test), Q value = 0.84

Table S1444. Gene #131: 'HTT MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
HTT MUTATED	2	3	0
HTT WILD-TYPE	236	188	228

'HTT MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.341 (Fisher's exact test), Q value = 0.98

Table S1445. Gene #131: 'HTT MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
HTT MUTATED	0	2	3
HTT WILD-TYPE	196	189	267

'HTT MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.26 (Fisher's exact test), Q value = 0.91

Table S1446. Gene #131: 'HTT MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
HTT MUTATED	0	2	0	3
HTT WILD-TYPE	140	105	83	179

'HTT MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0232 (Fisher's exact test), Q value = 0.25

Table S1447. Gene #131: 'HTT MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
HTT MUTATED	0	2	3
HTT WILD-TYPE	223	184	100

Figure S250. Get High-res Image Gene #131: 'HTT MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'HTT MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S1448. Gene #131: 'HTT MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
HTT MUTATED	0	1	1	3
HTT WILD-TYPE	127	118	105	153

'HTT MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.525 (Fisher's exact test), Q value = 1

Table S1449. Gene #131: 'HTT MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
HTT MUTATED	0	2	2	0	0	1
HTT WILD-TYPE	99	75	118	57	63	91

'SON MUTATION STATUS' versus 'CN_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S1450. Gene #132: 'SON MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SON MUTATED	3	6	0
SON WILD-TYPE	289	426	62

'SON MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S1451. Gene #132: 'SON MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SON MUTATED	3	2	1	2
SON WILD-TYPE	150	221	87	159

'SON MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S1452. Gene #132: 'SON MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
SON MUTATED	4	2	0	1
SON WILD-TYPE	181	153	138	94

'SON MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S1453. Gene #132: 'SON MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
SON MUTATED	4	1	2
SON WILD-TYPE	201	219	146

'SON MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S1454. Gene #132: 'SON MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SON MUTATED	4	1	4
SON WILD-TYPE	234	190	224

'SON MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S1455. Gene #132: 'SON MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SON MUTATED	3	3	3
SON WILD-TYPE	193	188	267

'SON MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.827 (Fisher's exact test), Q value = 1

Table S1456. Gene #132: 'SON MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
SON MUTATED	2	2	2	2
SON WILD-TYPE	138	105	81	180

'SON MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.519 (Fisher's exact test), Q value = 1

Table S1457. Gene #132: 'SON MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
SON MUTATED	3	2	3
SON WILD-TYPE	220	184	100

'SON MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 0.89

Table S1458. Gene #132: 'SON MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
SON MUTATED	0	1	3	3
SON WILD-TYPE	127	118	103	153

'SON MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0302 (Fisher's exact test), Q value = 0.3

Table S1459. Gene #132: 'SON MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
SON MUTATED	1	0	0	0	3	3
SON WILD-TYPE	98	77	120	57	60	89

Figure S251. Get High-res Image Gene #132: 'SON MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PLXNA3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 0.86

Table S1460. Gene #133: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PLXNA3 MUTATED	2	6	2
PLXNA3 WILD-TYPE	290	426	60

'PLXNA3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S1461. Gene #133: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
PLXNA3 MUTATED	2	2	2	4
PLXNA3 WILD-TYPE	151	221	86	157

'PLXNA3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0309 (Fisher's exact test), Q value = 0.3

Table S1462. Gene #133: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PLXNA3 MUTATED	7	0	1	2
PLXNA3 WILD-TYPE	178	155	137	93

Figure S252. Get High-res Image Gene #133: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'PLXNA3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.521 (Fisher's exact test), Q value = 1

Table S1463. Gene #133: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PLXNA3 MUTATED	5	4	1
PLXNA3 WILD-TYPE	200	216	147

'PLXNA3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.407 (Fisher's exact test), Q value = 1

Table S1464. Gene #133: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
PLXNA3 MUTATED	4	1	5
PLXNA3 WILD-TYPE	234	190	223

'PLXNA3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.609 (Fisher's exact test), Q value = 1

Table S1465. Gene #133: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
PLXNA3 MUTATED	3	4	3
PLXNA3 WILD-TYPE	193	187	267

'PLXNA3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S1466. Gene #133: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
PLXNA3 MUTATED	3	3	2	1
PLXNA3 WILD-TYPE	137	104	81	181

'PLXNA3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.226 (Fisher's exact test), Q value = 0.88

Table S1467. Gene #133: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
PLXNA3 MUTATED	5	1	3
PLXNA3 WILD-TYPE	218	185	100

'PLXNA3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.548 (Fisher's exact test), Q value = 1

Table S1468. Gene #133: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
PLXNA3 MUTATED	3	3	2	1
PLXNA3 WILD-TYPE	124	116	104	155

'PLXNA3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.272 (Fisher's exact test), Q value = 0.91

Table S1469. Gene #133: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
PLXNA3 MUTATED	1	2	0	1	2	3
PLXNA3 WILD-TYPE	98	75	120	56	61	89

'PASD1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.194 (Fisher's exact test), Q value = 0.83

Table S1470. Gene #134: 'PASD1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
PASD1 MUTATED	3	1	0	0
PASD1 WILD-TYPE	67	97	44	63

'PASD1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.00839 (Fisher's exact test), Q value = 0.13

Table S1471. Gene #134: 'PASD1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PASD1 MUTATED	0	0	4
PASD1 WILD-TYPE	138	61	72

Figure S253. Get High-res Image Gene #134: 'PASD1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

'PASD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.856 (Fisher's exact test), Q value = 1

Table S1472. Gene #134: 'PASD1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PASD1 MUTATED	4	4	0
PASD1 WILD-TYPE	288	428	62

'PASD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.463 (Fisher's exact test), Q value = 1

Table S1473. Gene #134: 'PASD1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
PASD1 MUTATED	2	1	2	2
PASD1 WILD-TYPE	151	222	86	159

'PASD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1474. Gene #134: 'PASD1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PASD1 MUTATED	2	2	2	1
PASD1 WILD-TYPE	183	153	136	94

'PASD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.898 (Fisher's exact test), Q value = 1

Table S1475. Gene #134: 'PASD1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PASD1 MUTATED	3	2	2
PASD1 WILD-TYPE	202	218	146

'PASD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.33 (Fisher's exact test), Q value = 0.97

Table S1476. Gene #134: 'PASD1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
PASD1 MUTATED	0	2	2
PASD1 WILD-TYPE	238	189	226

'PASD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.313 (Fisher's exact test), Q value = 0.94

Table S1477. Gene #134: 'PASD1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
PASD1 MUTATED	0	1	3
PASD1 WILD-TYPE	196	190	267

'PASD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.914 (Fisher's exact test), Q value = 1

Table S1478. Gene #134: 'PASD1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
PASD1 MUTATED	1	1	1	1
PASD1 WILD-TYPE	139	106	82	181

'PASD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.42 (Fisher's exact test), Q value = 1

Table S1479. Gene #134: 'PASD1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
PASD1 MUTATED	1	3	0
PASD1 WILD-TYPE	222	183	103

'PASD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.259 (Fisher's exact test), Q value = 0.91

Table S1480. Gene #134: 'PASD1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
PASD1 MUTATED	0	1	0	3
PASD1 WILD-TYPE	127	118	106	153

'PASD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.496 (Fisher's exact test), Q value = 1

Table S1481. Gene #134: 'PASD1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
PASD1 MUTATED	0	2	1	0	0	1
PASD1 WILD-TYPE	99	75	119	57	63	91

'AMPD1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S1482. Gene #135: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
AMPD1 MUTATED	1	1	1	0
AMPD1 WILD-TYPE	77	40	63	57

'AMPD1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.267 (Fisher's exact test), Q value = 0.91

Table S1483. Gene #135: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
AMPD1 MUTATED	2	0	1	0
AMPD1 WILD-TYPE	61	50	47	79

'AMPD1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.521 (Fisher's exact test), Q value = 1

Table S1484. Gene #135: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
AMPD1 MUTATED	2	1	0	0
AMPD1 WILD-TYPE	68	97	44	63

'AMPD1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.196 (Fisher's exact test), Q value = 0.83

Table S1485. Gene #135: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
AMPD1 MUTATED	1	2	0
AMPD1 WILD-TYPE	137	59	76

'AMPD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.197 (Fisher's exact test), Q value = 0.83

Table S1486. Gene #135: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
AMPD1 MUTATED	5	2	0
AMPD1 WILD-TYPE	287	430	62

'AMPD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 0.63

Table S1487. Gene #135: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
AMPD1 MUTATED	4	2	0	0
AMPD1 WILD-TYPE	149	221	88	161

'AMPD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.411 (Fisher's exact test), Q value = 1

Table S1488. Gene #135: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
AMPD1 MUTATED	1	0	2	0
AMPD1 WILD-TYPE	184	155	136	95

'AMPD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S1489. Gene #135: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
AMPD1 MUTATED	2	1	0
AMPD1 WILD-TYPE	203	219	148

'AMPD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S1490. Gene #135: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
AMPD1 MUTATED	4	2	1
AMPD1 WILD-TYPE	234	189	227

'AMPD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.89 (Fisher's exact test), Q value = 1

Table S1491. Gene #135: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
AMPD1 MUTATED	3	2	2
AMPD1 WILD-TYPE	193	189	268

'AMPD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S1492. Gene #135: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
AMPD1 MUTATED	0	2	0	2
AMPD1 WILD-TYPE	140	105	83	180

'AMPD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.339 (Fisher's exact test), Q value = 0.98

Table S1493. Gene #135: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
AMPD1 MUTATED	1	1	2
AMPD1 WILD-TYPE	222	185	101

'AMPD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.288 (Fisher's exact test), Q value = 0.93

Table S1494. Gene #135: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
AMPD1 MUTATED	1	0	0	3
AMPD1 WILD-TYPE	126	119	106	153

'AMPD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.945 (Fisher's exact test), Q value = 1

Table S1495. Gene #135: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
AMPD1 MUTATED	1	0	2	0	0	1
AMPD1 WILD-TYPE	98	77	118	57	63	91

'TNFSF9 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.525 (Fisher's exact test), Q value = 1

Table S1496. Gene #136: 'TNFSF9 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
TNFSF9 MUTATED	2	1	0	0
TNFSF9 WILD-TYPE	68	97	44	63

'TNFSF9 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.312 (Fisher's exact test), Q value = 0.94

Table S1497. Gene #136: 'TNFSF9 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TNFSF9 MUTATED	1	0	2
TNFSF9 WILD-TYPE	137	61	74

'TNFSF9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S1498. Gene #136: 'TNFSF9 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TNFSF9 MUTATED	3	2	0
TNFSF9 WILD-TYPE	289	430	62

'TNFSF9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.368 (Fisher's exact test), Q value = 1

Table S1499. Gene #136: 'TNFSF9 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TNFSF9 MUTATED	3	1	0	1
TNFSF9 WILD-TYPE	150	222	88	160

'TNFSF9 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.326 (Fisher's exact test), Q value = 0.97

Table S1500. Gene #136: 'TNFSF9 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TNFSF9 MUTATED	2	0	1	2
TNFSF9 WILD-TYPE	183	155	137	93

'TNFSF9 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S1501. Gene #136: 'TNFSF9 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TNFSF9 MUTATED	2	3	0
TNFSF9 WILD-TYPE	203	217	148

'IL4R MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.847 (Fisher's exact test), Q value = 1

Table S1502. Gene #137: 'IL4R MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
IL4R MUTATED	1	1	2	2
IL4R WILD-TYPE	77	40	62	55

'IL4R MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S1503. Gene #137: 'IL4R MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
IL4R MUTATED	0	1	2	3
IL4R WILD-TYPE	63	49	46	76

'IL4R MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.744 (Fisher's exact test), Q value = 1

Table S1504. Gene #137: 'IL4R MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
IL4R MUTATED	1	3	2	2
IL4R WILD-TYPE	69	95	42	61

'IL4R MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.803 (Fisher's exact test), Q value = 1

Table S1505. Gene #137: 'IL4R MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
IL4R MUTATED	4	1	3
IL4R WILD-TYPE	134	60	73

'IL4R MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0308 (Fisher's exact test), Q value = 0.3

Table S1506. Gene #137: 'IL4R MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
IL4R MUTATED	8	2	0
IL4R WILD-TYPE	284	430	62

Figure S254. Get High-res Image Gene #137: 'IL4R MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'IL4R MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S1507. Gene #137: 'IL4R MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
IL4R MUTATED	2	1	1	1
IL4R WILD-TYPE	151	222	87	160

'IL4R MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S1508. Gene #137: 'IL4R MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
IL4R MUTATED	2	4	3	0
IL4R WILD-TYPE	183	151	135	95

'IL4R MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.643 (Fisher's exact test), Q value = 1

Table S1509. Gene #137: 'IL4R MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
IL4R MUTATED	2	5	2
IL4R WILD-TYPE	203	215	146

'IL4R MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.142 (Fisher's exact test), Q value = 0.71

Table S1510. Gene #137: 'IL4R MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
IL4R MUTATED	4	2	0
IL4R WILD-TYPE	234	189	228

'IL4R MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0938 (Fisher's exact test), Q value = 0.57

Table S1511. Gene #137: 'IL4R MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
IL4R MUTATED	4	0	2
IL4R WILD-TYPE	192	191	268

'TJAP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0505 (Fisher's exact test), Q value = 0.41

Table S1512. Gene #138: 'TJAP1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TJAP1 MUTATED	2	0	1
TJAP1 WILD-TYPE	290	432	61

'TJAP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0171 (Fisher's exact test), Q value = 0.21

Table S1513. Gene #138: 'TJAP1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TJAP1 MUTATED	3	0	0	0
TJAP1 WILD-TYPE	150	223	88	161

Figure S255. Get High-res Image Gene #138: 'TJAP1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'KLKB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1514. Gene #139: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
KLKB1 MUTATED	3	4	0
KLKB1 WILD-TYPE	289	428	62

'KLKB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S1515. Gene #139: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
KLKB1 MUTATED	1	3	0	1
KLKB1 WILD-TYPE	152	220	88	160

'KLKB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.247 (Fisher's exact test), Q value = 0.9

Table S1516. Gene #139: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
KLKB1 MUTATED	4	2	0	0
KLKB1 WILD-TYPE	181	153	138	95

'KLKB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1517. Gene #139: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
KLKB1 MUTATED	2	2	2
KLKB1 WILD-TYPE	203	218	146

'KLKB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1518. Gene #139: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
KLKB1 MUTATED	2	2	2
KLKB1 WILD-TYPE	236	189	226

'KLKB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.595 (Fisher's exact test), Q value = 1

Table S1519. Gene #139: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
KLKB1 MUTATED	1	3	2
KLKB1 WILD-TYPE	195	188	268

'KLKB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.928 (Fisher's exact test), Q value = 1

Table S1520. Gene #139: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
KLKB1 MUTATED	2	1	0	2
KLKB1 WILD-TYPE	138	106	83	180

'KLKB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1521. Gene #139: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
KLKB1 MUTATED	2	2	1
KLKB1 WILD-TYPE	221	184	102

'KLKB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.291 (Fisher's exact test), Q value = 0.93

Table S1522. Gene #139: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
KLKB1 MUTATED	2	0	0	3
KLKB1 WILD-TYPE	125	119	106	153

'KLKB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S1523. Gene #139: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
KLKB1 MUTATED	2	0	2	0	0	1
KLKB1 WILD-TYPE	97	77	118	57	63	91

'CHGB MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.783 (Fisher's exact test), Q value = 1

Table S1524. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
CHGB MUTATED	2	0	1	0
CHGB WILD-TYPE	76	41	63	57

'CHGB MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S1525. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
CHGB MUTATED	2	0	0	1
CHGB WILD-TYPE	61	50	48	78

'CHGB MUTATION STATUS' versus 'MIR_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1526. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
CHGB MUTATED	1	2	0	1
CHGB WILD-TYPE	69	96	44	62

'CHGB MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.447 (Fisher's exact test), Q value = 1

Table S1527. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
CHGB MUTATED	1	1	2
CHGB WILD-TYPE	137	60	74

'CHGB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.361 (Fisher's exact test), Q value = 1

Table S1528. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
CHGB MUTATED	5	3	0
CHGB WILD-TYPE	287	429	62

'CHGB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.587 (Fisher's exact test), Q value = 1

Table S1529. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
CHGB MUTATED	3	2	0	1
CHGB WILD-TYPE	150	221	88	160

'CHGB MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.913 (Fisher's exact test), Q value = 1

Table S1530. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
CHGB MUTATED	3	1	2	1
CHGB WILD-TYPE	182	154	136	94

'CHGB MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 0.94

Table S1531. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
CHGB MUTATED	3	4	0
CHGB WILD-TYPE	202	216	148

'CHGB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.881 (Fisher's exact test), Q value = 1

Table S1532. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
CHGB MUTATED	3	1	2
CHGB WILD-TYPE	235	190	226

'CHGB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.389 (Fisher's exact test), Q value = 1

Table S1533. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
CHGB MUTATED	2	3	1
CHGB WILD-TYPE	194	188	269

'CHGB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S1534. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
CHGB MUTATED	2	1	0	1
CHGB WILD-TYPE	138	106	83	181

'CHGB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 0.98

Table S1535. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
CHGB MUTATED	1	1	2
CHGB WILD-TYPE	222	185	101

'CHGB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.909 (Fisher's exact test), Q value = 1

Table S1536. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
CHGB MUTATED	1	1	0	2
CHGB WILD-TYPE	126	118	106	154

'CHGB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.856 (Fisher's exact test), Q value = 1

Table S1537. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
CHGB MUTATED	2	0	1	0	0	1
CHGB WILD-TYPE	97	77	119	57	63	91

'GABRA6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0495 (Fisher's exact test), Q value = 0.41

Table S1538. Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
GABRA6 MUTATED	1	0	6	2
GABRA6 WILD-TYPE	77	41	58	55

Figure S256. Get High-res Image Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'GABRA6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.533 (Fisher's exact test), Q value = 1

Table S1539. Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
GABRA6 MUTATED	1	1	3	4
GABRA6 WILD-TYPE	62	49	45	75

'GABRA6 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.168 (Fisher's exact test), Q value = 0.78

Table S1540. Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
GABRA6 MUTATED	5	4	2	0
GABRA6 WILD-TYPE	65	94	42	63

'GABRA6 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.112 (Fisher's exact test), Q value = 0.64

Table S1541. Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
GABRA6 MUTATED	3	2	6
GABRA6 WILD-TYPE	135	59	70

'GABRA6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00048 (Fisher's exact test), Q value = 0.013

Table S1542. Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
GABRA6 MUTATED	13	2	0
GABRA6 WILD-TYPE	279	430	62

Figure S257. Get High-res Image Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'GABRA6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0085 (Fisher's exact test), Q value = 0.13

Table S1543. Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
GABRA6 MUTATED	7	2	1	0
GABRA6 WILD-TYPE	146	221	87	161

Figure S258. Get High-res Image Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'GABRA6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S1544. Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
GABRA6 MUTATED	2	3	3	2
GABRA6 WILD-TYPE	183	152	135	93

'GABRA6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.924 (Fisher's exact test), Q value = 1

Table S1545. Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
GABRA6 MUTATED	3	4	3
GABRA6 WILD-TYPE	202	216	145

'GABRA6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00247 (Fisher's exact test), Q value = 0.054

Table S1546. Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
GABRA6 MUTATED	9	2	0
GABRA6 WILD-TYPE	229	189	228

Figure S259. Get High-res Image Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'GABRA6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0922 (Fisher's exact test), Q value = 0.57

Table S1547. Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
GABRA6 MUTATED	7	2	2
GABRA6 WILD-TYPE	189	189	268

'GABRA6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S1548. Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
GABRA6 MUTATED	1	2	0	1
GABRA6 WILD-TYPE	139	105	83	181

'GABRA6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0132 (Fisher's exact test), Q value = 0.18

Table S1549. Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
GABRA6 MUTATED	0	1	3
GABRA6 WILD-TYPE	223	185	100

Figure S260. Get High-res Image Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'GABRA6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.908 (Fisher's exact test), Q value = 1

Table S1550. Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
GABRA6 MUTATED	1	1	0	2
GABRA6 WILD-TYPE	126	118	106	154

'GABRA6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.856 (Fisher's exact test), Q value = 1

Table S1551. Gene #141: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
GABRA6 MUTATED	0	1	1	0	1	1
GABRA6 WILD-TYPE	99	76	119	57	62	91

'ALPK3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.503 (Fisher's exact test), Q value = 1

Table S1552. Gene #142: 'ALPK3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ALPK3 MUTATED	3	1	0
ALPK3 WILD-TYPE	289	431	62

'ALPK3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0173 (Fisher's exact test), Q value = 0.21

Table S1553. Gene #142: 'ALPK3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ALPK3 MUTATED	3	0	0	0
ALPK3 WILD-TYPE	150	223	88	161

Figure S261. Get High-res Image Gene #142: 'ALPK3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'ALPK3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S1554. Gene #142: 'ALPK3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ALPK3 MUTATED	2	1	0	0
ALPK3 WILD-TYPE	183	154	138	95

'ALPK3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1555. Gene #142: 'ALPK3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ALPK3 MUTATED	1	1	1
ALPK3 WILD-TYPE	204	219	147

'MYO1B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.524 (Fisher's exact test), Q value = 1

Table S1556. Gene #143: 'MYO1B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
MYO1B MUTATED	1	1	1	3
MYO1B WILD-TYPE	77	40	63	54

'MYO1B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.732 (Fisher's exact test), Q value = 1

Table S1557. Gene #143: 'MYO1B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
MYO1B MUTATED	2	1	0	3
MYO1B WILD-TYPE	61	49	48	76

'MYO1B MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.292 (Fisher's exact test), Q value = 0.93

Table S1558. Gene #143: 'MYO1B MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
MYO1B MUTATED	3	2	2	0
MYO1B WILD-TYPE	67	96	42	63

'MYO1B MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.521 (Fisher's exact test), Q value = 1

Table S1559. Gene #143: 'MYO1B MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
MYO1B MUTATED	2	2	3
MYO1B WILD-TYPE	136	59	73

'MYO1B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0514 (Fisher's exact test), Q value = 0.41

Table S1560. Gene #143: 'MYO1B MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
MYO1B MUTATED	7	2	1
MYO1B WILD-TYPE	285	430	61

'MYO1B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S1561. Gene #143: 'MYO1B MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
MYO1B MUTATED	3	2	0	1
MYO1B WILD-TYPE	150	221	88	160

'MYO1B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.458 (Fisher's exact test), Q value = 1

Table S1562. Gene #143: 'MYO1B MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
MYO1B MUTATED	2	4	2	0
MYO1B WILD-TYPE	183	151	136	95

'MYO1B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S1563. Gene #143: 'MYO1B MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
MYO1B MUTATED	2	2	4
MYO1B WILD-TYPE	203	218	144

'MYO1B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.072 (Fisher's exact test), Q value = 0.48

Table S1564. Gene #143: 'MYO1B MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
MYO1B MUTATED	5	3	0
MYO1B WILD-TYPE	233	188	228

'MYO1B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 0.84

Table S1565. Gene #143: 'MYO1B MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
MYO1B MUTATED	5	1	2
MYO1B WILD-TYPE	191	190	268

'MYO1B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S1566. Gene #143: 'MYO1B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
MYO1B MUTATED	1	0	0	3
MYO1B WILD-TYPE	139	107	83	179

'MYO1B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S1567. Gene #143: 'MYO1B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
MYO1B MUTATED	1	2	1
MYO1B WILD-TYPE	222	184	102

'MYO1B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.259 (Fisher's exact test), Q value = 0.91

Table S1568. Gene #143: 'MYO1B MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
MYO1B MUTATED	0	1	0	3
MYO1B WILD-TYPE	127	118	106	153

'MYO1B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.57 (Fisher's exact test), Q value = 1

Table S1569. Gene #143: 'MYO1B MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
MYO1B MUTATED	0	1	2	0	1	0
MYO1B WILD-TYPE	99	76	118	57	62	92

'SMOC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.751 (Fisher's exact test), Q value = 1

Table S1570. Gene #144: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SMOC1 MUTATED	1	3	0
SMOC1 WILD-TYPE	291	429	62

'SMOC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.387 (Fisher's exact test), Q value = 1

Table S1571. Gene #144: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SMOC1 MUTATED	0	2	1	0
SMOC1 WILD-TYPE	153	221	87	161

'SMOC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S1572. Gene #144: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SMOC1 MUTATED	1	1	2
SMOC1 WILD-TYPE	237	190	226

'SMOC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S1573. Gene #144: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SMOC1 MUTATED	1	2	1
SMOC1 WILD-TYPE	195	189	269

'SMOC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S1574. Gene #144: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
SMOC1 MUTATED	2	0	0	1
SMOC1 WILD-TYPE	138	107	83	181

'SMOC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1575. Gene #144: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
SMOC1 MUTATED	2	1	0
SMOC1 WILD-TYPE	221	185	103

'SMOC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.374 (Fisher's exact test), Q value = 1

Table S1576. Gene #144: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
SMOC1 MUTATED	0	2	0	1
SMOC1 WILD-TYPE	127	117	106	155

'SMOC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.648 (Fisher's exact test), Q value = 1

Table S1577. Gene #144: 'SMOC1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
SMOC1 MUTATED	2	0	1	0	0	0
SMOC1 WILD-TYPE	97	77	119	57	63	92

'ACSM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.246 (Fisher's exact test), Q value = 0.9

Table S1578. Gene #145: 'ACSM1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ACSM1 MUTATED	4	2	1
ACSM1 WILD-TYPE	288	430	61

'ACSM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.208 (Fisher's exact test), Q value = 0.85

Table S1579. Gene #145: 'ACSM1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ACSM1 MUTATED	3	3	0	0
ACSM1 WILD-TYPE	150	220	88	161

'ACSM1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S1580. Gene #145: 'ACSM1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ACSM1 MUTATED	1	1	2	0
ACSM1 WILD-TYPE	184	154	136	95

'ACSM1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.138 (Fisher's exact test), Q value = 0.7

Table S1581. Gene #145: 'ACSM1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ACSM1 MUTATED	3	0	1
ACSM1 WILD-TYPE	202	220	147

'ACSM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S1582. Gene #145: 'ACSM1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
ACSM1 MUTATED	2	2	1
ACSM1 WILD-TYPE	236	189	227

'ACSM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.193 (Fisher's exact test), Q value = 0.83

Table S1583. Gene #145: 'ACSM1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
ACSM1 MUTATED	0	3	2
ACSM1 WILD-TYPE	196	188	268

'ACSM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.262 (Fisher's exact test), Q value = 0.91

Table S1584. Gene #145: 'ACSM1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
ACSM1 MUTATED	0	2	0	3
ACSM1 WILD-TYPE	140	105	83	179

'ACSM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 0.64

Table S1585. Gene #145: 'ACSM1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
ACSM1 MUTATED	1	1	3
ACSM1 WILD-TYPE	222	185	100

'ACSM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 0.89

Table S1586. Gene #145: 'ACSM1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
ACSM1 MUTATED	0	2	0	3
ACSM1 WILD-TYPE	127	117	106	153

'ACSM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S1587. Gene #145: 'ACSM1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
ACSM1 MUTATED	0	2	2	0	0	1
ACSM1 WILD-TYPE	99	75	118	57	63	91

'CIB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.347 (Fisher's exact test), Q value = 0.99

Table S1588. Gene #146: 'CIB1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
CIB1 MUTATED	1	3	1
CIB1 WILD-TYPE	291	429	61

'CIB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.931 (Fisher's exact test), Q value = 1

Table S1589. Gene #146: 'CIB1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
CIB1 MUTATED	1	2	0	2
CIB1 WILD-TYPE	152	221	88	159

'CIB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.766 (Fisher's exact test), Q value = 1

Table S1590. Gene #146: 'CIB1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
CIB1 MUTATED	2	1	2	0
CIB1 WILD-TYPE	183	154	136	95

'CIB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0509 (Fisher's exact test), Q value = 0.41

Table S1591. Gene #146: 'CIB1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
CIB1 MUTATED	4	0	1
CIB1 WILD-TYPE	201	220	147

'CIB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 1

Table S1592. Gene #146: 'CIB1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
CIB1 MUTATED	1	2	1
CIB1 WILD-TYPE	237	189	227

'CIB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.312 (Fisher's exact test), Q value = 0.94

Table S1593. Gene #146: 'CIB1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
CIB1 MUTATED	0	1	3
CIB1 WILD-TYPE	196	190	267

'CIB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 0.86

Table S1594. Gene #146: 'CIB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
CIB1 MUTATED	0	1	2	1
CIB1 WILD-TYPE	140	106	81	181

'CIB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0436 (Fisher's exact test), Q value = 0.39

Table S1595. Gene #146: 'CIB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
CIB1 MUTATED	0	4	0
CIB1 WILD-TYPE	223	182	103

Figure S262. Get High-res Image Gene #146: 'CIB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'CIB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.574 (Fisher's exact test), Q value = 1

Table S1596. Gene #146: 'CIB1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
CIB1 MUTATED	0	2	1	1
CIB1 WILD-TYPE	127	117	105	155

'CIB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.259 (Fisher's exact test), Q value = 0.91

Table S1597. Gene #146: 'CIB1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
CIB1 MUTATED	0	2	1	1	0	0
CIB1 WILD-TYPE	99	75	119	56	63	92

'TTC30B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S1598. Gene #148: 'TTC30B MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TTC30B MUTATED	2	5	0
TTC30B WILD-TYPE	290	427	62

'TTC30B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.646 (Fisher's exact test), Q value = 1

Table S1599. Gene #148: 'TTC30B MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TTC30B MUTATED	1	4	0	1
TTC30B WILD-TYPE	152	219	88	160

'TTC30B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S1600. Gene #148: 'TTC30B MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TTC30B MUTATED	1	1	0	1
TTC30B WILD-TYPE	184	154	138	94

'TTC30B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.189 (Fisher's exact test), Q value = 0.83

Table S1601. Gene #148: 'TTC30B MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TTC30B MUTATED	1	0	2
TTC30B WILD-TYPE	204	220	146

'TTC30B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S1602. Gene #148: 'TTC30B MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
TTC30B MUTATED	2	1	4
TTC30B WILD-TYPE	236	190	224

'TTC30B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.345 (Fisher's exact test), Q value = 0.99

Table S1603. Gene #148: 'TTC30B MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
TTC30B MUTATED	1	4	2
TTC30B WILD-TYPE	195	187	268

'TTC30B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0767 (Fisher's exact test), Q value = 0.5

Table S1604. Gene #148: 'TTC30B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
TTC30B MUTATED	1	4	0	1
TTC30B WILD-TYPE	139	103	83	181

'TTC30B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.585 (Fisher's exact test), Q value = 1

Table S1605. Gene #148: 'TTC30B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
TTC30B MUTATED	4	1	1
TTC30B WILD-TYPE	219	185	102

'TTC30B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S1606. Gene #148: 'TTC30B MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
TTC30B MUTATED	1	1	1	3
TTC30B WILD-TYPE	126	118	105	153

'TTC30B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S1607. Gene #148: 'TTC30B MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
TTC30B MUTATED	1	0	1	1	0	3
TTC30B WILD-TYPE	98	77	119	56	63	89

'AGXT2L1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.5 (Fisher's exact test), Q value = 1

Table S1608. Gene #149: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
AGXT2L1 MUTATED	3	1	0
AGXT2L1 WILD-TYPE	289	431	62

'AGXT2L1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 0.89

Table S1609. Gene #149: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
AGXT2L1 MUTATED	2	0	0	1
AGXT2L1 WILD-TYPE	151	223	88	160

'AGXT2L1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.211 (Fisher's exact test), Q value = 0.85

Table S1610. Gene #149: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
AGXT2L1 MUTATED	3	1	0
AGXT2L1 WILD-TYPE	235	190	228

'AGXT2L1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S1611. Gene #149: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
AGXT2L1 MUTATED	2	1	1
AGXT2L1 WILD-TYPE	194	190	269

'AGXT2L1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1612. Gene #149: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
AGXT2L1 MUTATED	1	1	0	1
AGXT2L1 WILD-TYPE	139	106	83	181

'AGXT2L1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S1613. Gene #149: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
AGXT2L1 MUTATED	1	1	1
AGXT2L1 WILD-TYPE	222	185	102

'AGXT2L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.56 (Fisher's exact test), Q value = 1

Table S1614. Gene #149: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
AGXT2L1 MUTATED	0	1	0	2
AGXT2L1 WILD-TYPE	127	118	106	154

'AGXT2L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1615. Gene #149: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
AGXT2L1 MUTATED	1	0	1	0	0	1
AGXT2L1 WILD-TYPE	98	77	119	57	63	91

'PRKCD MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0799 (Fisher's exact test), Q value = 0.52

Table S1616. Gene #150: 'PRKCD MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
PRKCD MUTATED	0	2	1	0
PRKCD WILD-TYPE	78	39	63	57

'PRKCD MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0842 (Fisher's exact test), Q value = 0.54

Table S1617. Gene #150: 'PRKCD MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PRKCD MUTATED	0	2	1	0
PRKCD WILD-TYPE	63	48	47	79

'PRKCD MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.235 (Fisher's exact test), Q value = 0.89

Table S1618. Gene #150: 'PRKCD MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
PRKCD MUTATED	0	3	0	0
PRKCD WILD-TYPE	70	95	44	63

'PRKCD MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1619. Gene #150: 'PRKCD MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PRKCD MUTATED	2	0	1
PRKCD WILD-TYPE	136	61	75

'PRKCD MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0503 (Fisher's exact test), Q value = 0.41

Table S1620. Gene #150: 'PRKCD MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PRKCD MUTATED	2	0	1
PRKCD WILD-TYPE	290	432	61

'ST3GAL6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.246 (Fisher's exact test), Q value = 0.9

Table S1621. Gene #151: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ST3GAL6 MUTATED	4	1	0
ST3GAL6 WILD-TYPE	288	431	62

'ST3GAL6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.23 (Fisher's exact test), Q value = 0.89

Table S1622. Gene #151: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ST3GAL6 MUTATED	2	0	0	1
ST3GAL6 WILD-TYPE	151	223	88	160

'ST3GAL6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S1623. Gene #151: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ST3GAL6 MUTATED	2	0	1	1
ST3GAL6 WILD-TYPE	183	155	137	94

'ST3GAL6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0206 (Fisher's exact test), Q value = 0.23

Table S1624. Gene #151: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ST3GAL6 MUTATED	4	0	0
ST3GAL6 WILD-TYPE	201	220	148

Figure S263. Get High-res Image Gene #151: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

'ST3GAL6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0829 (Fisher's exact test), Q value = 0.53

Table S1625. Gene #151: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
ST3GAL6 MUTATED	4	1	0
ST3GAL6 WILD-TYPE	234	190	228

'ST3GAL6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S1626. Gene #151: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
ST3GAL6 MUTATED	3	1	1
ST3GAL6 WILD-TYPE	193	190	269

'ST3GAL6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1627. Gene #151: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
ST3GAL6 MUTATED	1	1	0	1
ST3GAL6 WILD-TYPE	139	106	83	181

'ST3GAL6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0519 (Fisher's exact test), Q value = 0.41

Table S1628. Gene #151: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
ST3GAL6 MUTATED	0	1	2
ST3GAL6 WILD-TYPE	223	185	101

'ST3GAL6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S1629. Gene #151: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
ST3GAL6 MUTATED	1	0	0	2
ST3GAL6 WILD-TYPE	126	119	106	154

'ST3GAL6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.132 (Fisher's exact test), Q value = 0.69

Table S1630. Gene #151: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
ST3GAL6 MUTATED	0	0	0	0	1	2
ST3GAL6 WILD-TYPE	99	77	120	57	62	90

'SOX13 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S1631. Gene #152: 'SOX13 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
SOX13 MUTATED	1	1	1	0
SOX13 WILD-TYPE	69	97	43	63

'SOX13 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1632. Gene #152: 'SOX13 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
SOX13 MUTATED	2	0	1
SOX13 WILD-TYPE	136	61	75

'SOX13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0143 (Fisher's exact test), Q value = 0.18

Table S1633. Gene #152: 'SOX13 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SOX13 MUTATED	5	0	0
SOX13 WILD-TYPE	287	432	62

Figure S264. Get High-res Image Gene #152: 'SOX13 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'SOX13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0102 (Fisher's exact test), Q value = 0.15

Table S1634. Gene #152: 'SOX13 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SOX13 MUTATED	4	0	0	0
SOX13 WILD-TYPE	149	223	88	161

Figure S265. Get High-res Image Gene #152: 'SOX13 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'SOX13 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.416 (Fisher's exact test), Q value = 1

Table S1635. Gene #152: 'SOX13 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
SOX13 MUTATED	1	1	3	0
SOX13 WILD-TYPE	184	154	135	95

'SOX13 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1636. Gene #152: 'SOX13 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
SOX13 MUTATED	2	2	1
SOX13 WILD-TYPE	203	218	147

'SOX13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S1637. Gene #152: 'SOX13 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SOX13 MUTATED	2	1	0
SOX13 WILD-TYPE	236	190	228

'SOX13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1638. Gene #152: 'SOX13 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SOX13 MUTATED	1	1	1
SOX13 WILD-TYPE	195	190	269

'NKX2-2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.642 (Fisher's exact test), Q value = 1

Table S1639. Gene #153: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
NKX2-2 MUTATED	1	5	0
NKX2-2 WILD-TYPE	291	427	62

'NKX2-2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.896 (Fisher's exact test), Q value = 1

Table S1640. Gene #153: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
NKX2-2 MUTATED	1	3	1	1
NKX2-2 WILD-TYPE	152	220	87	160

'NKX2-2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.551 (Fisher's exact test), Q value = 1

Table S1641. Gene #153: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
NKX2-2 MUTATED	3	2	0	1
NKX2-2 WILD-TYPE	182	153	138	94

'NKX2-2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.886 (Fisher's exact test), Q value = 1

Table S1642. Gene #153: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
NKX2-2 MUTATED	2	3	1
NKX2-2 WILD-TYPE	203	217	147

'NKX2-2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.338 (Fisher's exact test), Q value = 0.98

Table S1643. Gene #153: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
NKX2-2 MUTATED	1	1	4
NKX2-2 WILD-TYPE	237	190	224

'NKX2-2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0182 (Fisher's exact test), Q value = 0.21

Table S1644. Gene #153: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
NKX2-2 MUTATED	0	5	1
NKX2-2 WILD-TYPE	196	186	269

Figure S266. Get High-res Image Gene #153: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'NKX2-2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.802 (Fisher's exact test), Q value = 1

Table S1645. Gene #153: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
NKX2-2 MUTATED	2	2	0	2
NKX2-2 WILD-TYPE	138	105	83	180

'NKX2-2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1646. Gene #153: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
NKX2-2 MUTATED	3	2	1
NKX2-2 WILD-TYPE	220	184	102

'NKX2-2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S1647. Gene #153: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
NKX2-2 MUTATED	1	1	1	3
NKX2-2 WILD-TYPE	126	118	105	153

'NKX2-2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.73 (Fisher's exact test), Q value = 1

Table S1648. Gene #153: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
NKX2-2 MUTATED	1	2	1	0	0	2
NKX2-2 WILD-TYPE	98	75	119	57	63	90

'SYBU MUTATION STATUS' versus 'CN_CNMF'

P value = 0.271 (Fisher's exact test), Q value = 0.91

Table S1649. Gene #154: 'SYBU MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SYBU MUTATED	1	1	1
SYBU WILD-TYPE	291	431	61

'SYBU MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S1650. Gene #154: 'SYBU MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SYBU MUTATED	1	2	0	0
SYBU WILD-TYPE	152	221	88	161

'SYBU MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S1651. Gene #154: 'SYBU MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
SYBU MUTATED	1	1	0	1
SYBU WILD-TYPE	184	154	138	94

'SYBU MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1652. Gene #154: 'SYBU MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
SYBU MUTATED	1	1	1
SYBU WILD-TYPE	204	219	147

'WDR90 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0775 (Fisher's exact test), Q value = 0.51

Table S1653. Gene #155: 'WDR90 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
WDR90 MUTATED	0	1	3	0
WDR90 WILD-TYPE	78	40	61	57

'WDR90 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.365 (Fisher's exact test), Q value = 1

Table S1654. Gene #155: 'WDR90 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
WDR90 MUTATED	0	1	2	1
WDR90 WILD-TYPE	63	49	46	78

'WDR90 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.0197 (Fisher's exact test), Q value = 0.23

Table S1655. Gene #155: 'WDR90 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
WDR90 MUTATED	0	6	0	0
WDR90 WILD-TYPE	70	92	44	63

Figure S267. Get High-res Image Gene #155: 'WDR90 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

'WDR90 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.558 (Fisher's exact test), Q value = 1

Table S1656. Gene #155: 'WDR90 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
WDR90 MUTATED	4	0	2
WDR90 WILD-TYPE	134	61	74

'WDR90 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.256 (Fisher's exact test), Q value = 0.91

Table S1657. Gene #155: 'WDR90 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
WDR90 MUTATED	6	3	0
WDR90 WILD-TYPE	286	429	62

'WDR90 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.418 (Fisher's exact test), Q value = 1

Table S1658. Gene #155: 'WDR90 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
WDR90 MUTATED	3	1	0	2
WDR90 WILD-TYPE	150	222	88	159

'WDR90 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.471 (Fisher's exact test), Q value = 1

Table S1659. Gene #155: 'WDR90 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
WDR90 MUTATED	3	1	3	0
WDR90 WILD-TYPE	182	154	135	95

'WDR90 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 0.64

Table S1660. Gene #155: 'WDR90 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
WDR90 MUTATED	5	2	0
WDR90 WILD-TYPE	200	218	148

'WDR90 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0734 (Fisher's exact test), Q value = 0.49

Table S1661. Gene #155: 'WDR90 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
WDR90 MUTATED	5	2	0
WDR90 WILD-TYPE	233	189	228

'WDR90 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S1662. Gene #155: 'WDR90 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
WDR90 MUTATED	4	1	2
WDR90 WILD-TYPE	192	190	268

'WDR90 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.521 (Fisher's exact test), Q value = 1

Table S1663. Gene #155: 'WDR90 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
WDR90 MUTATED	0	1	1	1
WDR90 WILD-TYPE	140	106	82	181

'WDR90 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S1664. Gene #155: 'WDR90 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
WDR90 MUTATED	1	1	1
WDR90 WILD-TYPE	222	185	102

'WDR90 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.49 (Fisher's exact test), Q value = 1

Table S1665. Gene #155: 'WDR90 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
WDR90 MUTATED	0	0	1	2
WDR90 WILD-TYPE	127	119	105	154

'WDR90 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S1666. Gene #155: 'WDR90 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
WDR90 MUTATED	0	0	1	1	0	1
WDR90 WILD-TYPE	99	77	119	56	63	91

'TP63 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.929 (Fisher's exact test), Q value = 1

Table S1667. Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
TP63 MUTATED	1	1	2	1
TP63 WILD-TYPE	77	40	62	56

'TP63 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.729 (Fisher's exact test), Q value = 1

Table S1668. Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
TP63 MUTATED	1	1	2	1
TP63 WILD-TYPE	62	49	46	78

'TP63 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.317 (Fisher's exact test), Q value = 0.95

Table S1669. Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
TP63 MUTATED	2	1	0	3
TP63 WILD-TYPE	68	97	44	60

'TP63 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.648 (Fisher's exact test), Q value = 1

Table S1670. Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TP63 MUTATED	2	2	2
TP63 WILD-TYPE	136	59	74

'TP63 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 0.98

Table S1671. Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
TP63 MUTATED	6	4	0
TP63 WILD-TYPE	286	428	62

'TP63 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0495 (Fisher's exact test), Q value = 0.41

Table S1672. Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
TP63 MUTATED	5	3	0	0
TP63 WILD-TYPE	148	220	88	161

Figure S268. Get High-res Image Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'TP63 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0245 (Fisher's exact test), Q value = 0.26

Table S1673. Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
TP63 MUTATED	1	0	5	2
TP63 WILD-TYPE	184	155	133	93

Figure S269. Get High-res Image Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'TP63 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.141 (Fisher's exact test), Q value = 0.71

Table S1674. Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
TP63 MUTATED	5	3	0
TP63 WILD-TYPE	200	217	148

'TP63 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.142 (Fisher's exact test), Q value = 0.71

Table S1675. Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
TP63 MUTATED	5	0	2
TP63 WILD-TYPE	233	191	226

'TP63 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0224 (Fisher's exact test), Q value = 0.24

Table S1676. Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
TP63 MUTATED	3	4	0
TP63 WILD-TYPE	193	187	270

Figure S270. Get High-res Image Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'TP63 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.335 (Fisher's exact test), Q value = 0.98

Table S1677. Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
TP63 MUTATED	2	1	1	0
TP63 WILD-TYPE	138	106	82	182

'TP63 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.264 (Fisher's exact test), Q value = 0.91

Table S1678. Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
TP63 MUTATED	3	0	1
TP63 WILD-TYPE	220	186	102

'TP63 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0685 (Fisher's exact test), Q value = 0.48

Table S1679. Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
TP63 MUTATED	1	3	0	0
TP63 WILD-TYPE	126	116	106	156

'TP63 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.137 (Fisher's exact test), Q value = 0.7

Table S1680. Gene #156: 'TP63 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
TP63 MUTATED	2	2	0	0	0	0
TP63 WILD-TYPE	97	75	120	57	63	92

'AK7 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0975 (Fisher's exact test), Q value = 0.59

Table S1681. Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
AK7 MUTATED	0	0	2	3
AK7 WILD-TYPE	78	41	62	54

'AK7 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.127 (Fisher's exact test), Q value = 0.67

Table S1682. Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
AK7 MUTATED	0	0	1	4
AK7 WILD-TYPE	63	50	47	75

'AK7 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.628 (Fisher's exact test), Q value = 1

Table S1683. Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
AK7 MUTATED	1	3	1	0
AK7 WILD-TYPE	69	95	43	63

'AK7 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.235 (Fisher's exact test), Q value = 0.89

Table S1684. Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
AK7 MUTATED	2	0	3
AK7 WILD-TYPE	136	61	73

'AK7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0127 (Fisher's exact test), Q value = 0.18

Table S1685. Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
AK7 MUTATED	7	1	1
AK7 WILD-TYPE	285	431	61

Figure S271. Get High-res Image Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'AK7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0574 (Fisher's exact test), Q value = 0.44

Table S1686. Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
AK7 MUTATED	4	1	0	0
AK7 WILD-TYPE	149	222	88	161

'AK7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S1687. Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
AK7 MUTATED	1	3	2	1
AK7 WILD-TYPE	184	152	136	94

'AK7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.496 (Fisher's exact test), Q value = 1

Table S1688. Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
AK7 MUTATED	1	4	2
AK7 WILD-TYPE	204	216	146

'AK7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0167 (Fisher's exact test), Q value = 0.21

Table S1689. Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
AK7 MUTATED	6	1	0
AK7 WILD-TYPE	232	190	228

Figure S272. Get High-res Image Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'AK7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0863 (Fisher's exact test), Q value = 0.54

Table S1690. Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
AK7 MUTATED	5	1	1
AK7 WILD-TYPE	191	190	269

'AK7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0683 (Fisher's exact test), Q value = 0.48

Table S1691. Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
AK7 MUTATED	0	3	0	1
AK7 WILD-TYPE	140	104	83	181

'AK7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00151 (Fisher's exact test), Q value = 0.034

Table S1692. Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
AK7 MUTATED	0	0	4
AK7 WILD-TYPE	223	186	99

Figure S273. Get High-res Image Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'AK7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.161 (Fisher's exact test), Q value = 0.76

Table S1693. Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
AK7 MUTATED	3	0	0	1
AK7 WILD-TYPE	124	119	106	155

'AK7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00717 (Fisher's exact test), Q value = 0.12

Table S1694. Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
AK7 MUTATED	0	1	0	0	3	0
AK7 WILD-TYPE	99	76	120	57	60	92

Figure S274. Get High-res Image Gene #157: 'AK7 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'SLC2A3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.249 (Fisher's exact test), Q value = 0.9

Table S1695. Gene #158: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SLC2A3 MUTATED	4	1	0
SLC2A3 WILD-TYPE	288	431	62

'SLC2A3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.23 (Fisher's exact test), Q value = 0.89

Table S1696. Gene #158: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SLC2A3 MUTATED	2	0	0	1
SLC2A3 WILD-TYPE	151	223	88	160

'SLC2A3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.361 (Fisher's exact test), Q value = 1

Table S1697. Gene #158: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
SLC2A3 MUTATED	3	0	1	0
SLC2A3 WILD-TYPE	182	155	137	95

'SLC2A3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.685 (Fisher's exact test), Q value = 1

Table S1698. Gene #158: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
SLC2A3 MUTATED	2	2	0
SLC2A3 WILD-TYPE	203	218	148

'SLC2A3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 0.85

Table S1699. Gene #158: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SLC2A3 MUTATED	3	1	0
SLC2A3 WILD-TYPE	235	190	228

'SLC2A3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S1700. Gene #158: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SLC2A3 MUTATED	2	1	1
SLC2A3 WILD-TYPE	194	190	269

'SLC2A3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0713 (Fisher's exact test), Q value = 0.48

Table S1701. Gene #158: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
SLC2A3 MUTATED	0	2	1	0
SLC2A3 WILD-TYPE	140	105	82	182

'SLC2A3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0513 (Fisher's exact test), Q value = 0.41

Table S1702. Gene #158: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
SLC2A3 MUTATED	0	1	2
SLC2A3 WILD-TYPE	223	185	101

'SLC2A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.892 (Fisher's exact test), Q value = 1

Table S1703. Gene #158: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
SLC2A3 MUTATED	1	0	1	1
SLC2A3 WILD-TYPE	126	119	105	155

'SLC2A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.242 (Fisher's exact test), Q value = 0.89

Table S1704. Gene #158: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
SLC2A3 MUTATED	0	0	0	1	1	1
SLC2A3 WILD-TYPE	99	77	120	56	62	91

'DSP MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.318 (Fisher's exact test), Q value = 0.95

Table S1705. Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
DSP MUTATED	2	0	2	4
DSP WILD-TYPE	76	41	62	53

'DSP MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S1706. Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
DSP MUTATED	2	1	2	3
DSP WILD-TYPE	61	49	46	76

'DSP MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S1707. Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
DSP MUTATED	4	5	2	1
DSP WILD-TYPE	66	93	42	62

'DSP MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.0713 (Fisher's exact test), Q value = 0.48

Table S1708. Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
DSP MUTATED	6	0	6
DSP WILD-TYPE	132	61	70

'DSP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0086 (Fisher's exact test), Q value = 0.13

Table S1709. Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
DSP MUTATED	14	5	2
DSP WILD-TYPE	278	427	60

Figure S275. Get High-res Image Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'DSP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.088 (Fisher's exact test), Q value = 0.55

Table S1710. Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
DSP MUTATED	8	3	2	2
DSP WILD-TYPE	145	220	86	159

'DSP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S1711. Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
DSP MUTATED	6	2	5	1
DSP WILD-TYPE	179	153	133	94

'DSP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S1712. Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
DSP MUTATED	5	7	2
DSP WILD-TYPE	200	213	146

'DSP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.725 (Fisher's exact test), Q value = 1

Table S1713. Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
DSP MUTATED	5	2	3
DSP WILD-TYPE	233	189	225

'DSP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.669 (Fisher's exact test), Q value = 1

Table S1714. Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
DSP MUTATED	4	3	3
DSP WILD-TYPE	192	188	267

'DSP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S1715. Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
DSP MUTATED	3	3	1	2
DSP WILD-TYPE	137	104	82	180

'DSP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0168 (Fisher's exact test), Q value = 0.21

Table S1716. Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
DSP MUTATED	5	0	4
DSP WILD-TYPE	218	186	99

Figure S276. Get High-res Image Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'DSP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.637 (Fisher's exact test), Q value = 1

Table S1717. Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
DSP MUTATED	3	1	3	2
DSP WILD-TYPE	124	118	103	154

'DSP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.237 (Fisher's exact test), Q value = 0.89

Table S1718. Gene #159: 'DSP MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
DSP MUTATED	2	1	0	1	3	2
DSP WILD-TYPE	97	76	120	56	60	90

'EGR1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S1719. Gene #160: 'EGR1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
EGR1 MUTATED	2	0	1	0
EGR1 WILD-TYPE	76	41	63	57

'EGR1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S1720. Gene #160: 'EGR1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
EGR1 MUTATED	1	0	0	2
EGR1 WILD-TYPE	62	50	48	77

'EGR1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.193 (Fisher's exact test), Q value = 0.83

Table S1721. Gene #160: 'EGR1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
EGR1 MUTATED	1	0	0	2
EGR1 WILD-TYPE	69	98	44	61

'EGR1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.195 (Fisher's exact test), Q value = 0.83

Table S1722. Gene #160: 'EGR1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
EGR1 MUTATED	1	2	0
EGR1 WILD-TYPE	137	59	76

'EGR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0472 (Fisher's exact test), Q value = 0.4

Table S1723. Gene #160: 'EGR1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
EGR1 MUTATED	2	1	2
EGR1 WILD-TYPE	290	431	60

Figure S277. Get High-res Image Gene #160: 'EGR1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'EGR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.168 (Fisher's exact test), Q value = 0.78

Table S1724. Gene #160: 'EGR1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
EGR1 MUTATED	3	0	0	0
EGR1 WILD-TYPE	182	155	138	95

'EGR1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0617 (Fisher's exact test), Q value = 0.46

Table S1725. Gene #160: 'EGR1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
EGR1 MUTATED	3	0	0
EGR1 WILD-TYPE	202	220	148

'EGR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.211 (Fisher's exact test), Q value = 0.85

Table S1726. Gene #160: 'EGR1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
EGR1 MUTATED	3	1	0
EGR1 WILD-TYPE	235	190	228

'EGR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S1727. Gene #160: 'EGR1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
EGR1 MUTATED	2	1	1
EGR1 WILD-TYPE	194	190	269

'PRB3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.269 (Fisher's exact test), Q value = 0.91

Table S1728. Gene #161: 'PRB3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PRB3 MUTATED	1	1	1
PRB3 WILD-TYPE	291	431	61

'PRB3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.596 (Fisher's exact test), Q value = 1

Table S1729. Gene #161: 'PRB3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
PRB3 MUTATED	1	1	1	0
PRB3 WILD-TYPE	152	222	87	161

'PRB3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.249 (Fisher's exact test), Q value = 0.9

Table S1730. Gene #161: 'PRB3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PRB3 MUTATED	0	1	2	0
PRB3 WILD-TYPE	185	154	136	95

'PRB3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1731. Gene #161: 'PRB3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PRB3 MUTATED	1	1	1
PRB3 WILD-TYPE	204	219	147

'PRB3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S1732. Gene #161: 'PRB3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
PRB3 MUTATED	2	1	0
PRB3 WILD-TYPE	236	190	228

'PRB3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1733. Gene #161: 'PRB3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
PRB3 MUTATED	1	1	1
PRB3 WILD-TYPE	195	190	269

'FBN3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.346 (Fisher's exact test), Q value = 0.99

Table S1734. Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
FBN3 MUTATED	2	1	5	1
FBN3 WILD-TYPE	76	40	59	56

'FBN3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.31 (Fisher's exact test), Q value = 0.94

Table S1735. Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
FBN3 MUTATED	1	2	4	2
FBN3 WILD-TYPE	62	48	44	77

'FBN3 MUTATION STATUS' versus 'MIR_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1736. Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
FBN3 MUTATED	3	4	2	2
FBN3 WILD-TYPE	67	94	42	61

'FBN3 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.921 (Fisher's exact test), Q value = 1

Table S1737. Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
FBN3 MUTATED	5	3	3
FBN3 WILD-TYPE	133	58	73

'FBN3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00795 (Fisher's exact test), Q value = 0.13

Table S1738. Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
FBN3 MUTATED	13	4	1
FBN3 WILD-TYPE	279	428	61

Figure S278. Get High-res Image Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'FBN3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0139 (Fisher's exact test), Q value = 0.18

Table S1739. Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
FBN3 MUTATED	7	1	2	1
FBN3 WILD-TYPE	146	222	86	160

Figure S279. Get High-res Image Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'FBN3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S1740. Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
FBN3 MUTATED	2	4	4	2
FBN3 WILD-TYPE	183	151	134	93

'FBN3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S1741. Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
FBN3 MUTATED	5	4	3
FBN3 WILD-TYPE	200	216	145

'FBN3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0557 (Fisher's exact test), Q value = 0.43

Table S1742. Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
FBN3 MUTATED	8	3	1
FBN3 WILD-TYPE	230	188	227

'FBN3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.111 (Fisher's exact test), Q value = 0.63

Table S1743. Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
FBN3 MUTATED	7	2	3
FBN3 WILD-TYPE	189	189	267

'FBN3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S1744. Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
FBN3 MUTATED	3	1	0	3
FBN3 WILD-TYPE	137	106	83	179

'FBN3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0545 (Fisher's exact test), Q value = 0.43

Table S1745. Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
FBN3 MUTATED	1	2	4
FBN3 WILD-TYPE	222	184	99

'FBN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S1746. Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
FBN3 MUTATED	2	1	0	4
FBN3 WILD-TYPE	125	118	106	152

'FBN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.285 (Fisher's exact test), Q value = 0.93

Table S1747. Gene #162: 'FBN3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
FBN3 MUTATED	1	0	2	0	3	1
FBN3 WILD-TYPE	98	77	118	57	60	91

'FLNB MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.62 (Fisher's exact test), Q value = 1

Table S1748. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
FLNB MUTATED	2	0	0	1
FLNB WILD-TYPE	76	41	64	56

'FLNB MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.348 (Fisher's exact test), Q value = 0.99

Table S1749. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
FLNB MUTATED	2	1	0	0
FLNB WILD-TYPE	61	49	48	79

'FLNB MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.151 (Fisher's exact test), Q value = 0.73

Table S1750. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
FLNB MUTATED	2	0	1	0
FLNB WILD-TYPE	68	98	43	63

'FLNB MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S1751. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
FLNB MUTATED	2	1	0
FLNB WILD-TYPE	136	60	76

'FLNB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0484 (Fisher's exact test), Q value = 0.41

Table S1752. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
FLNB MUTATED	2	4	3
FLNB WILD-TYPE	290	428	59

Figure S280. Get High-res Image Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'FLNB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.954 (Fisher's exact test), Q value = 1

Table S1753. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
FLNB MUTATED	1	3	1	2
FLNB WILD-TYPE	152	220	87	159

'FLNB MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S1754. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
FLNB MUTATED	2	3	1	1
FLNB WILD-TYPE	183	152	137	94

'FLNB MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.71 (Fisher's exact test), Q value = 1

Table S1755. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
FLNB MUTATED	2	4	1
FLNB WILD-TYPE	203	216	147

'FLNB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.916 (Fisher's exact test), Q value = 1

Table S1756. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
FLNB MUTATED	4	2	3
FLNB WILD-TYPE	234	189	225

'FLNB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.406 (Fisher's exact test), Q value = 1

Table S1757. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
FLNB MUTATED	3	4	2
FLNB WILD-TYPE	193	187	268

'FLNB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S1758. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
FLNB MUTATED	2	3	0	2
FLNB WILD-TYPE	138	104	83	180

'FLNB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.784 (Fisher's exact test), Q value = 1

Table S1759. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
FLNB MUTATED	3	2	2
FLNB WILD-TYPE	220	184	101

'FLNB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.461 (Fisher's exact test), Q value = 1

Table S1760. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
FLNB MUTATED	3	1	0	3
FLNB WILD-TYPE	124	118	106	153

'FLNB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.971 (Fisher's exact test), Q value = 1

Table S1761. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
FLNB MUTATED	1	1	2	0	1	2
FLNB WILD-TYPE	98	76	118	57	62	90

'SLFN11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S1762. Gene #164: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SLFN11 MUTATED	2	4	1
SLFN11 WILD-TYPE	290	428	61

'SLFN11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.648 (Fisher's exact test), Q value = 1

Table S1763. Gene #164: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SLFN11 MUTATED	1	4	0	1
SLFN11 WILD-TYPE	152	219	88	160

'SLFN11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.529 (Fisher's exact test), Q value = 1

Table S1764. Gene #164: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
SLFN11 MUTATED	4	2	1	0
SLFN11 WILD-TYPE	181	153	137	95

'SLFN11 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.899 (Fisher's exact test), Q value = 1

Table S1765. Gene #164: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
SLFN11 MUTATED	3	2	2
SLFN11 WILD-TYPE	202	218	146

'SLFN11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1766. Gene #164: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SLFN11 MUTATED	2	2	2
SLFN11 WILD-TYPE	236	189	226

'SLFN11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.076 (Fisher's exact test), Q value = 0.5

Table S1767. Gene #164: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SLFN11 MUTATED	0	4	2
SLFN11 WILD-TYPE	196	187	268

'SLFN11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.37 (Fisher's exact test), Q value = 1

Table S1768. Gene #164: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
SLFN11 MUTATED	1	3	0	2
SLFN11 WILD-TYPE	139	104	83	180

'SLFN11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.12 (Fisher's exact test), Q value = 0.65

Table S1769. Gene #164: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
SLFN11 MUTATED	4	0	2
SLFN11 WILD-TYPE	219	186	101

'SLFN11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S1770. Gene #164: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
SLFN11 MUTATED	3	1	0	2
SLFN11 WILD-TYPE	124	118	106	154

'SLFN11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.271 (Fisher's exact test), Q value = 0.91

Table S1771. Gene #164: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
SLFN11 MUTATED	1	1	0	1	0	3
SLFN11 WILD-TYPE	98	76	120	56	63	89

'SEZ6L2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S1772. Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
SEZ6L2 MUTATED	3	0	0	1
SEZ6L2 WILD-TYPE	75	41	64	56

'SEZ6L2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.47 (Fisher's exact test), Q value = 1

Table S1773. Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
SEZ6L2 MUTATED	1	0	0	3
SEZ6L2 WILD-TYPE	62	50	48	76

'SEZ6L2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S1774. Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
SEZ6L2 MUTATED	2	1	1	0
SEZ6L2 WILD-TYPE	68	97	43	63

'SEZ6L2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.123 (Fisher's exact test), Q value = 0.66

Table S1775. Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
SEZ6L2 MUTATED	1	0	3
SEZ6L2 WILD-TYPE	137	61	73

'SEZ6L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 1

Table S1776. Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
SEZ6L2 MUTATED	4	3	0
SEZ6L2 WILD-TYPE	288	429	62

'SEZ6L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.826 (Fisher's exact test), Q value = 1

Table S1777. Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
SEZ6L2 MUTATED	1	1	0	2
SEZ6L2 WILD-TYPE	152	222	88	159

'SEZ6L2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0182 (Fisher's exact test), Q value = 0.21

Table S1778. Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
SEZ6L2 MUTATED	0	4	0	0
SEZ6L2 WILD-TYPE	185	151	138	95

Figure S281. Get High-res Image Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'SEZ6L2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.00429 (Fisher's exact test), Q value = 0.084

Table S1779. Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
SEZ6L2 MUTATED	0	0	4
SEZ6L2 WILD-TYPE	205	220	144

Figure S282. Get High-res Image Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

'SEZ6L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.204 (Fisher's exact test), Q value = 0.84

Table S1780. Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
SEZ6L2 MUTATED	2	3	0
SEZ6L2 WILD-TYPE	236	188	228

'SEZ6L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1781. Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
SEZ6L2 MUTATED	2	1	2
SEZ6L2 WILD-TYPE	194	190	268

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.24 (Fisher's exact test), Q value = 0.89

Table S1782. Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
SEZ6L2 MUTATED	0	0	0	3
SEZ6L2 WILD-TYPE	140	107	83	179

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0987 (Fisher's exact test), Q value = 0.59

Table S1783. Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
SEZ6L2 MUTATED	0	3	0
SEZ6L2 WILD-TYPE	223	183	103

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0651 (Fisher's exact test), Q value = 0.47

Table S1784. Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
SEZ6L2 MUTATED	0	0	0	3
SEZ6L2 WILD-TYPE	127	119	106	153

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.183 (Fisher's exact test), Q value = 0.83

Table S1785. Gene #165: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
SEZ6L2 MUTATED	0	0	3	0	0	0
SEZ6L2 WILD-TYPE	99	77	117	57	63	92

'MAX MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1786. Gene #166: 'MAX MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
MAX MUTATED	2	4	0
MAX WILD-TYPE	290	428	62

'MAX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.147 (Fisher's exact test), Q value = 0.72

Table S1787. Gene #166: 'MAX MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
MAX MUTATED	1	0	1	3
MAX WILD-TYPE	152	223	87	158

'MAX MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.561 (Fisher's exact test), Q value = 1

Table S1788. Gene #166: 'MAX MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
MAX MUTATED	1	3	1	0
MAX WILD-TYPE	184	152	137	95

'MAX MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1789. Gene #166: 'MAX MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
MAX MUTATED	2	2	1
MAX WILD-TYPE	203	218	147

'MAX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.744 (Fisher's exact test), Q value = 1

Table S1790. Gene #166: 'MAX MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
MAX MUTATED	1	2	2
MAX WILD-TYPE	237	189	226

'MAX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.237 (Fisher's exact test), Q value = 0.89

Table S1791. Gene #166: 'MAX MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
MAX MUTATED	1	0	4
MAX WILD-TYPE	195	191	266

'MAX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 0.92

Table S1792. Gene #166: 'MAX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
MAX MUTATED	0	0	1	3
MAX WILD-TYPE	140	107	82	179

'MAX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.832 (Fisher's exact test), Q value = 1

Table S1793. Gene #166: 'MAX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
MAX MUTATED	2	2	0
MAX WILD-TYPE	221	184	103

'MAX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.231 (Fisher's exact test), Q value = 0.89

Table S1794. Gene #166: 'MAX MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
MAX MUTATED	0	0	2	2
MAX WILD-TYPE	127	119	104	154

'MAX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.46 (Fisher's exact test), Q value = 1

Table S1795. Gene #166: 'MAX MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
MAX MUTATED	0	1	2	1	0	0
MAX WILD-TYPE	99	76	118	56	63	92

'ZNF148 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1796. Gene #167: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
ZNF148 MUTATED	2	3	0
ZNF148 WILD-TYPE	290	429	62

'ZNF148 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 0.64

Table S1797. Gene #167: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
ZNF148 MUTATED	2	0	0	3
ZNF148 WILD-TYPE	151	223	88	158

'ZNF148 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S1798. Gene #167: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
ZNF148 MUTATED	2	0	2	0
ZNF148 WILD-TYPE	183	155	136	95

'ZNF148 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.139 (Fisher's exact test), Q value = 0.7

Table S1799. Gene #167: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
ZNF148 MUTATED	3	0	1
ZNF148 WILD-TYPE	202	220	147

'ZNF148 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1800. Gene #167: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
ZNF148 MUTATED	2	1	2
ZNF148 WILD-TYPE	236	190	226

'ZNF148 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.739 (Fisher's exact test), Q value = 1

Table S1801. Gene #167: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
ZNF148 MUTATED	1	1	3
ZNF148 WILD-TYPE	195	190	267

'ZNF148 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 1

Table S1802. Gene #167: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
ZNF148 MUTATED	1	2	0	1
ZNF148 WILD-TYPE	139	105	83	181

'ZNF148 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.261 (Fisher's exact test), Q value = 0.91

Table S1803. Gene #167: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
ZNF148 MUTATED	3	0	1
ZNF148 WILD-TYPE	220	186	102

'ZNF148 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S1804. Gene #167: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
ZNF148 MUTATED	1	0	1	2
ZNF148 WILD-TYPE	126	119	105	154

'ZNF148 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0246 (Fisher's exact test), Q value = 0.26

Table S1805. Gene #167: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
ZNF148 MUTATED	0	0	0	2	0	2
ZNF148 WILD-TYPE	99	77	120	55	63	90

Figure S283. Get High-res Image Gene #167: 'ZNF148 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PAN3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.719 (Fisher's exact test), Q value = 1

Table S1806. Gene #168: 'PAN3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
PAN3 MUTATED	3	0	1	1
PAN3 WILD-TYPE	75	41	63	56

'PAN3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 0.94

Table S1807. Gene #168: 'PAN3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PAN3 MUTATED	2	2	1	0
PAN3 WILD-TYPE	61	48	47	79

'PAN3 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.253 (Fisher's exact test), Q value = 0.9

Table S1808. Gene #168: 'PAN3 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
PAN3 MUTATED	3	3	0	0
PAN3 WILD-TYPE	67	95	44	63

'PAN3 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.645 (Fisher's exact test), Q value = 1

Table S1809. Gene #168: 'PAN3 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PAN3 MUTATED	2	2	2
PAN3 WILD-TYPE	136	59	74

'PAN3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.247 (Fisher's exact test), Q value = 0.9

Table S1810. Gene #168: 'PAN3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PAN3 MUTATED	4	2	1
PAN3 WILD-TYPE	288	430	61

'PAN3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 0.94

Table S1811. Gene #168: 'PAN3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PAN3 MUTATED	2	0	0	1
PAN3 WILD-TYPE	183	155	138	94

'PAN3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.366 (Fisher's exact test), Q value = 1

Table S1812. Gene #168: 'PAN3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PAN3 MUTATED	2	0	1
PAN3 WILD-TYPE	203	220	147

'PAN3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S1813. Gene #168: 'PAN3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
PAN3 MUTATED	2	1	0
PAN3 WILD-TYPE	236	190	228

'PAN3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S1814. Gene #168: 'PAN3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
PAN3 MUTATED	2	0	1
PAN3 WILD-TYPE	194	191	269

'PPL MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 0.9

Table S1815. Gene #169: 'PPL MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
PPL MUTATED	0	0	1	2
PPL WILD-TYPE	78	41	63	55

'PPL MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.702 (Fisher's exact test), Q value = 1

Table S1816. Gene #169: 'PPL MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PPL MUTATED	0	1	1	1
PPL WILD-TYPE	63	49	47	78

'PPL MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.69 (Fisher's exact test), Q value = 1

Table S1817. Gene #169: 'PPL MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
PPL MUTATED	0	2	0	1
PPL WILD-TYPE	70	96	44	62

'PPL MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S1818. Gene #169: 'PPL MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PPL MUTATED	1	1	1
PPL WILD-TYPE	137	60	75

'PPL MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1819. Gene #169: 'PPL MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
PPL MUTATED	3	5	0
PPL WILD-TYPE	289	427	62

'PPL MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S1820. Gene #169: 'PPL MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
PPL MUTATED	2	4	0	2
PPL WILD-TYPE	151	219	88	159

'PPL MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.237 (Fisher's exact test), Q value = 0.89

Table S1821. Gene #169: 'PPL MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
PPL MUTATED	4	0	3	1
PPL WILD-TYPE	181	155	135	94

'PPL MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.163 (Fisher's exact test), Q value = 0.77

Table S1822. Gene #169: 'PPL MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
PPL MUTATED	3	5	0
PPL WILD-TYPE	202	215	148

'PPL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 0.94

Table S1823. Gene #169: 'PPL MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
PPL MUTATED	5	3	1
PPL WILD-TYPE	233	188	227

'PPL MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S1824. Gene #169: 'PPL MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
PPL MUTATED	2	4	3
PPL WILD-TYPE	194	187	267

'PPL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.137 (Fisher's exact test), Q value = 0.7

Table S1825. Gene #169: 'PPL MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
PPL MUTATED	0	3	0	3
PPL WILD-TYPE	140	104	83	179

'PPL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.758 (Fisher's exact test), Q value = 1

Table S1826. Gene #169: 'PPL MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
PPL MUTATED	2	2	2
PPL WILD-TYPE	221	184	101

'PPL MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S1827. Gene #169: 'PPL MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
PPL MUTATED	1	2	2	1
PPL WILD-TYPE	126	117	104	155

'PPL MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.126 (Fisher's exact test), Q value = 0.67

Table S1828. Gene #169: 'PPL MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
PPL MUTATED	1	3	0	0	0	2
PPL WILD-TYPE	98	74	120	57	63	90

'IGFN1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1829. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	78	41	64	57
IGFN1 MUTATED	1	1	1	1
IGFN1 WILD-TYPE	77	40	63	56

'IGFN1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1830. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
IGFN1 MUTATED	1	1	1	1
IGFN1 WILD-TYPE	62	49	47	78

'IGFN1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.726 (Fisher's exact test), Q value = 1

Table S1831. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	70	98	44	63
IGFN1 MUTATED	2	1	1	2
IGFN1 WILD-TYPE	68	97	43	61

'IGFN1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.559 (Fisher's exact test), Q value = 1

Table S1832. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
IGFN1 MUTATED	4	0	2
IGFN1 WILD-TYPE	134	61	74

'IGFN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0146 (Fisher's exact test), Q value = 0.19

Table S1833. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
IGFN1 MUTATED	7	1	0
IGFN1 WILD-TYPE	285	431	62

Figure S284. Get High-res Image Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'IGFN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00295 (Fisher's exact test), Q value = 0.063

Table S1834. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
IGFN1 MUTATED	5	0	1	0
IGFN1 WILD-TYPE	148	223	87	161

Figure S285. Get High-res Image Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'IGFN1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S1835. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
IGFN1 MUTATED	2	2	1	0
IGFN1 WILD-TYPE	183	153	137	95

'IGFN1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.641 (Fisher's exact test), Q value = 1

Table S1836. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
IGFN1 MUTATED	2	1	2
IGFN1 WILD-TYPE	203	219	146

'IGFN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0316 (Fisher's exact test), Q value = 0.31

Table S1837. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
IGFN1 MUTATED	5	1	0
IGFN1 WILD-TYPE	233	190	228

Figure S286. Get High-res Image Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'IGFN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.19 (Fisher's exact test), Q value = 0.83

Table S1838. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
IGFN1 MUTATED	4	1	1
IGFN1 WILD-TYPE	192	190	269

'IGFN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1839. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
IGFN1 MUTATED	1	1	0	1
IGFN1 WILD-TYPE	139	106	83	181

'IGFN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00841 (Fisher's exact test), Q value = 0.13

Table S1840. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
IGFN1 MUTATED	0	0	3
IGFN1 WILD-TYPE	223	186	100

Figure S287. Get High-res Image Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'IGFN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.559 (Fisher's exact test), Q value = 1

Table S1841. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
IGFN1 MUTATED	0	1	0	2
IGFN1 WILD-TYPE	127	118	106	154

'IGFN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0728 (Fisher's exact test), Q value = 0.49

Table S1842. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
IGFN1 MUTATED	0	0	0	0	2	1
IGFN1 WILD-TYPE	99	77	120	57	61	91

'GLYAT MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1843. Gene #171: 'GLYAT MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	292	432	62
GLYAT MUTATED	2	3	0
GLYAT WILD-TYPE	290	429	62

'GLYAT MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.871 (Fisher's exact test), Q value = 1

Table S1844. Gene #171: 'GLYAT MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	153	223	88	161
GLYAT MUTATED	2	2	0	1
GLYAT WILD-TYPE	151	221	88	160

'GLYAT MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S1845. Gene #171: 'GLYAT MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	185	155	138	95
GLYAT MUTATED	2	0	2	0
GLYAT WILD-TYPE	183	155	136	95

'GLYAT MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S1846. Gene #171: 'GLYAT MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	205	220	148
GLYAT MUTATED	2	2	0
GLYAT WILD-TYPE	203	218	148

'GLYAT MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 0.97

Table S1847. Gene #171: 'GLYAT MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	238	191	228
GLYAT MUTATED	2	0	3
GLYAT WILD-TYPE	236	191	225

'GLYAT MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S1848. Gene #171: 'GLYAT MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	191	270
GLYAT MUTATED	1	3	1
GLYAT WILD-TYPE	195	188	269

'GLYAT MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.196 (Fisher's exact test), Q value = 0.83

Table S1849. Gene #171: 'GLYAT MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	140	107	83	182
GLYAT MUTATED	1	2	1	0
GLYAT WILD-TYPE	139	105	82	182

'GLYAT MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.261 (Fisher's exact test), Q value = 0.91

Table S1850. Gene #171: 'GLYAT MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	223	186	103
GLYAT MUTATED	3	0	1
GLYAT WILD-TYPE	220	186	102

'GLYAT MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1851. Gene #171: 'GLYAT MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	127	119	106	156
GLYAT MUTATED	1	1	1	1
GLYAT WILD-TYPE	126	118	105	155

'GLYAT MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S1852. Gene #171: 'GLYAT MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	99	77	120	57	63	92
GLYAT MUTATED	1	1	0	1	0	1
GLYAT WILD-TYPE	98	76	120	56	63	91

Methods & Data

Input

Mutation data file = sample_sig_gene_table.txt from Mutsig_2CV pipeline
Processed Mutation data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/GBMLGG-TP/22818079/transformed.cor.cli.txt
Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/GBMLGG-TP/22573865/GBMLGG-TP.transferedmergedcluster.txt
Number of patients = 799
Number of significantly mutated genes = 171
Number of Molecular subtypes = 14
Exclude genes that fewer than K tumors have mutations, K = 3

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

References

[1] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)

[2] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)

Made with Nozzle