This pipeline computes the correlation between significant arm-level copy number variations (cnvs) and molecular subtypes.
Testing the association between copy number variation 82 arm-level events and 12 molecular subtypes across 516 patients, 500 significant findings detected with P value < 0.05 and Q value < 0.25.
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1p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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1q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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2p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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2q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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4q gain cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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5p gain cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5q gain cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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6p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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6q gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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7p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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7q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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8q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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9p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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9q gain cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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10p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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13q gain cnv correlated to 'METHLYATION_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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14q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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15q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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16p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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16q gain cnv correlated to 'CN_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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17p gain cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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17q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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21q gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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22q gain cnv correlated to 'MRNASEQ_CHIERARCHICAL'.
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xp gain cnv correlated to 'METHLYATION_CNMF' and 'MIRSEQ_MATURE_CNMF'.
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xq gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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1p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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1q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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2p loss cnv correlated to 'MIRSEQ_CNMF'.
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3p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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4p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6p loss cnv correlated to 'METHLYATION_CNMF'.
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6q loss cnv correlated to 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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7p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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7q loss cnv correlated to 'CN_CNMF'.
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8p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8q loss cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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9p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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9q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10p loss cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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10q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11p loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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11q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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12p loss cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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12q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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13q loss cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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14q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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15q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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16p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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16q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17q loss cnv correlated to 'CN_CNMF'.
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18p loss cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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18q loss cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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21q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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22q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xp loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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xq loss cnv correlated to 'METHLYATION_CNMF'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 82 arm-level events and 12 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 500 significant findings detected.
|
Clinical Features |
MRNA CNMF |
MRNA CHIERARCHICAL |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| 20q gain | 201 (39%) | 315 |
0.0222 (0.0518) |
0.0239 (0.0543) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.0203 (0.0482) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
2e-05 (0.000144) |
0.00191 (0.00674) |
1e-05 (8.2e-05) |
| 4q loss | 136 (26%) | 380 |
0.00519 (0.0157) |
0.00706 (0.0196) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.0267 (0.0596) |
0.0184 (0.0441) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.00015 (0.000745) |
0.0003 (0.00135) |
| 5q loss | 143 (28%) | 373 |
0.03 (0.0655) |
0.0351 (0.0742) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
4e-05 (0.000243) |
6e-05 (0.000339) |
2e-05 (0.000144) |
2e-05 (0.000144) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
| 8q gain | 245 (47%) | 271 |
0.0376 (0.0789) |
0.0438 (0.0892) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.0763 (0.14) |
0.692 (0.782) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
6e-05 (0.000339) |
2e-05 (0.000144) |
0.00033 (0.00146) |
| 10p gain | 112 (22%) | 404 |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.00465 (0.0143) |
0.0207 (0.0486) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.00027 (0.00125) |
1e-05 (8.2e-05) |
0.00084 (0.00323) |
0.00028 (0.00129) |
||
| 12p gain | 138 (27%) | 378 |
0.0275 (0.061) |
0.0463 (0.093) |
1e-05 (8.2e-05) |
5e-05 (0.000296) |
0.0517 (0.101) |
0.082 (0.148) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.00253 (0.00867) |
2e-05 (0.000144) |
| 4p loss | 119 (23%) | 397 |
0.403 (0.51) |
0.408 (0.514) |
1e-05 (8.2e-05) |
0.0027 (0.00916) |
0.00117 (0.00436) |
0.00464 (0.0143) |
0.00048 (0.002) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.00866 (0.0235) |
0.00339 (0.0112) |
| 8p loss | 200 (39%) | 316 |
0.182 (0.28) |
0.0796 (0.145) |
1e-05 (8.2e-05) |
0.0299 (0.0653) |
0.0371 (0.0779) |
0.0333 (0.0712) |
2e-05 (0.000144) |
8e-05 (0.00044) |
0.0311 (0.0675) |
0.023 (0.0526) |
0.00067 (0.00268) |
0.0318 (0.0685) |
| 16p loss | 107 (21%) | 409 |
0.466 (0.57) |
0.483 (0.584) |
1e-05 (8.2e-05) |
0.00022 (0.00105) |
0.00331 (0.0109) |
0.00045 (0.00191) |
1e-05 (8.2e-05) |
0.00014 (0.000706) |
0.00696 (0.0196) |
0.00044 (0.00188) |
9e-05 (0.000487) |
0.00205 (0.0072) |
| 16q loss | 137 (27%) | 379 |
0.79 (0.862) |
0.622 (0.723) |
1e-05 (8.2e-05) |
3e-05 (0.000198) |
0.00029 (0.00132) |
0.00478 (0.0146) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.00602 (0.0175) |
0.00113 (0.00423) |
0.00132 (0.00485) |
0.00497 (0.015) |
| 19q loss | 159 (31%) | 357 |
0.686 (0.779) |
0.467 (0.57) |
0.00014 (0.000706) |
1e-05 (8.2e-05) |
0.0318 (0.0685) |
0.00073 (0.00287) |
0.00227 (0.00792) |
4e-05 (0.000243) |
0.00099 (0.00376) |
0.00067 (0.00268) |
0.00331 (0.0109) |
0.0113 (0.0295) |
| 21q loss | 166 (32%) | 350 |
0.0879 (0.156) |
0.141 (0.23) |
1e-05 (8.2e-05) |
0.00424 (0.0133) |
2e-05 (0.000144) |
0.0068 (0.0193) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
3e-05 (0.000198) |
0.00031 (0.00139) |
0.0001 (0.000532) |
1e-05 (8.2e-05) |
| 22q loss | 221 (43%) | 295 |
0.314 (0.42) |
0.168 (0.263) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.0165 (0.0408) |
0.0112 (0.0295) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
4e-05 (0.000243) |
1e-05 (8.2e-05) |
0.00582 (0.017) |
0.00048 (0.002) |
| 7p gain | 267 (52%) | 249 |
0.248 (0.355) |
0.315 (0.421) |
1e-05 (8.2e-05) |
0.083 (0.149) |
0.00434 (0.0136) |
0.00577 (0.0169) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.00293 (0.00981) |
1e-05 (8.2e-05) |
| 12q gain | 133 (26%) | 383 |
0.0872 (0.156) |
0.142 (0.23) |
1e-05 (8.2e-05) |
6e-05 (0.000339) |
0.0331 (0.0709) |
0.232 (0.337) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.00012 (0.000625) |
2e-05 (0.000144) |
| 20p gain | 175 (34%) | 341 |
0.113 (0.193) |
0.137 (0.224) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.253 (0.361) |
0.00181 (0.00643) |
2e-05 (0.000144) |
1e-05 (8.2e-05) |
3e-05 (0.000198) |
0.00019 (0.000912) |
0.00776 (0.0213) |
7e-05 (0.000389) |
| 1p loss | 80 (16%) | 436 |
0.0131 (0.0337) |
0.038 (0.0795) |
1e-05 (8.2e-05) |
0.00047 (0.00198) |
0.0385 (0.0805) |
0.634 (0.734) |
4e-05 (0.000243) |
4e-05 (0.000243) |
0.376 (0.483) |
0.00722 (0.02) |
0.00577 (0.0169) |
0.516 (0.617) |
| 5p loss | 45 (9%) | 471 |
0.296 (0.405) |
0.308 (0.417) |
4e-05 (0.000243) |
0.018 (0.0434) |
0.009 (0.0243) |
0.00023 (0.00108) |
0.106 (0.183) |
0.00595 (0.0173) |
0.0203 (0.0482) |
0.0175 (0.0424) |
0.0146 (0.0368) |
0.00235 (0.00814) |
| 19p loss | 245 (47%) | 271 |
1 (1.00) |
1 (1.00) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.00152 (0.00548) |
0.168 (0.263) |
2e-05 (0.000144) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
4e-05 (0.000243) |
3e-05 (0.000198) |
0.00142 (0.00518) |
| 2p gain | 154 (30%) | 362 |
0.114 (0.195) |
0.182 (0.28) |
1e-05 (8.2e-05) |
3e-05 (0.000198) |
0.238 (0.344) |
0.535 (0.638) |
4e-05 (0.000243) |
0.00019 (0.000912) |
1e-05 (8.2e-05) |
0.00045 (0.00191) |
0.0012 (0.00444) |
7e-05 (0.000389) |
| 2q gain | 143 (28%) | 373 |
0.205 (0.307) |
0.317 (0.423) |
2e-05 (0.000144) |
0.00029 (0.00132) |
0.566 (0.671) |
0.9 (0.951) |
0.0297 (0.0651) |
0.0115 (0.0299) |
0.0013 (0.00479) |
0.0139 (0.0355) |
0.00557 (0.0165) |
0.00479 (0.0146) |
| 3q gain | 90 (17%) | 426 |
0.201 (0.303) |
0.297 (0.406) |
3e-05 (0.000198) |
0.00057 (0.00234) |
0.0166 (0.041) |
0.22 (0.324) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.0179 (0.0432) |
0.192 (0.292) |
0.00064 (0.00258) |
0.027 (0.06) |
| 10q gain | 79 (15%) | 437 |
0.00051 (0.00212) |
0.00032 (0.00142) |
0.0459 (0.0926) |
0.74 (0.822) |
0.00076 (0.00297) |
1e-05 (8.2e-05) |
0.108 (0.185) |
0.00543 (0.0162) |
0.0241 (0.0546) |
0.0174 (0.0424) |
||
| 11q gain | 118 (23%) | 398 |
0.0178 (0.0432) |
0.0169 (0.0413) |
1e-05 (8.2e-05) |
0.209 (0.311) |
0.245 (0.353) |
0.318 (0.423) |
0.0308 (0.0669) |
5e-05 (0.000296) |
0.00017 (0.000828) |
6e-05 (0.000339) |
0.065 (0.122) |
0.00306 (0.0102) |
| 14q gain | 129 (25%) | 387 |
0.841 (0.906) |
0.844 (0.907) |
1e-05 (8.2e-05) |
0.0292 (0.0643) |
0.0818 (0.148) |
0.136 (0.223) |
0.00047 (0.00198) |
1e-05 (8.2e-05) |
0.00043 (0.00185) |
0.00015 (0.000745) |
0.00626 (0.018) |
0.0248 (0.0559) |
| 17q gain | 191 (37%) | 325 |
1 (1.00) |
0.635 (0.735) |
1e-05 (8.2e-05) |
0.00073 (0.00287) |
0.34 (0.445) |
0.216 (0.318) |
4e-05 (0.000243) |
1e-05 (8.2e-05) |
0.00094 (0.00359) |
7e-05 (0.000389) |
0.00286 (0.0096) |
0.00013 (0.000666) |
| 18p gain | 92 (18%) | 424 |
1 (1.00) |
1 (1.00) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.688 (0.78) |
0.95 (0.995) |
0.0137 (0.0349) |
0.00106 (0.004) |
0.00229 (0.00796) |
0.0356 (0.0751) |
0.00482 (0.0146) |
4e-05 (0.000243) |
| 18q gain | 69 (13%) | 447 |
0.318 (0.423) |
0.405 (0.511) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.078 (0.143) |
0.451 (0.556) |
4e-05 (0.000243) |
4e-05 (0.000243) |
0.00702 (0.0196) |
0.00166 (0.00592) |
1e-05 (8.2e-05) |
0.00052 (0.00215) |
| 10q loss | 132 (26%) | 384 |
0.776 (0.857) |
0.788 (0.862) |
1e-05 (8.2e-05) |
0.042 (0.0862) |
0.0557 (0.107) |
0.398 (0.506) |
0.00267 (0.00912) |
1e-05 (8.2e-05) |
0.00934 (0.025) |
0.00017 (0.000828) |
0.0425 (0.0871) |
0.007 (0.0196) |
| 11p loss | 111 (22%) | 405 |
0.0343 (0.0728) |
0.0704 (0.131) |
1e-05 (8.2e-05) |
0.00011 (0.000576) |
0.292 (0.402) |
0.023 (0.0526) |
0.00064 (0.00258) |
0.00016 (0.000787) |
0.111 (0.189) |
0.0417 (0.086) |
3e-05 (0.000198) |
0.241 (0.348) |
| 15q loss | 244 (47%) | 272 |
0.81 (0.88) |
0.655 (0.755) |
1e-05 (8.2e-05) |
0.00034 (0.00148) |
0.135 (0.222) |
0.224 (0.327) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
4e-05 (0.000243) |
0.00022 (0.00105) |
0.00419 (0.0132) |
0.00029 (0.00132) |
| 17p loss | 219 (42%) | 297 |
0.302 (0.41) |
0.144 (0.232) |
1e-05 (8.2e-05) |
6e-05 (0.000339) |
0.0184 (0.0441) |
0.364 (0.471) |
0.00076 (0.00297) |
6e-05 (0.000339) |
0.416 (0.522) |
0.011 (0.029) |
6e-05 (0.000339) |
0.0202 (0.0481) |
| 1q gain | 319 (62%) | 197 |
0.9 (0.951) |
1 (1.00) |
2e-05 (0.000144) |
0.00103 (0.0039) |
5e-05 (0.000296) |
0.00282 (0.0095) |
0.00187 (0.00662) |
0.0264 (0.0591) |
0.346 (0.451) |
2e-05 (0.000144) |
0.57 (0.675) |
0.385 (0.494) |
| 3p gain | 44 (9%) | 472 |
0.00827 (0.0225) |
0.00069 (0.00275) |
0.0216 (0.0505) |
0.78 (0.858) |
3e-05 (0.000198) |
0.00093 (0.00356) |
0.0802 (0.145) |
0.49 (0.59) |
0.00239 (0.00825) |
0.0131 (0.0337) |
||
| 7q gain | 220 (43%) | 296 |
0.529 (0.632) |
0.389 (0.497) |
1e-05 (8.2e-05) |
0.419 (0.524) |
0.0594 (0.113) |
0.598 (0.702) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.00402 (0.0128) |
0.00119 (0.00442) |
0.048 (0.0957) |
3e-05 (0.000198) |
| 11p gain | 94 (18%) | 422 |
0.00859 (0.0233) |
0.0107 (0.0283) |
0.00241 (0.00829) |
0.683 (0.777) |
0.128 (0.213) |
0.479 (0.582) |
0.129 (0.214) |
2e-05 (0.000144) |
6e-05 (0.000339) |
2e-05 (0.000144) |
0.0697 (0.13) |
0.00274 (0.00927) |
| 3p loss | 211 (41%) | 305 |
0.149 (0.238) |
0.242 (0.348) |
1e-05 (8.2e-05) |
0.00019 (0.000912) |
0.348 (0.453) |
0.189 (0.289) |
0.058 (0.111) |
2e-05 (0.000144) |
0.00813 (0.0222) |
0.00029 (0.00132) |
0.0112 (0.0295) |
0.0343 (0.0728) |
| 13q loss | 251 (49%) | 265 |
0.418 (0.523) |
0.622 (0.723) |
1e-05 (8.2e-05) |
0.109 (0.187) |
9e-05 (0.000487) |
0.282 (0.391) |
1e-05 (8.2e-05) |
2e-05 (0.000144) |
0.00321 (0.0107) |
0.00164 (0.00587) |
0.078 (0.143) |
0.0215 (0.0503) |
| 18q loss | 215 (42%) | 301 |
0.0945 (0.166) |
0.205 (0.307) |
1e-05 (8.2e-05) |
0.447 (0.552) |
0.0149 (0.0374) |
0.0786 (0.143) |
1e-05 (8.2e-05) |
3e-05 (0.000198) |
0.00614 (0.0178) |
0.932 (0.98) |
0.0104 (0.0277) |
0.0247 (0.0558) |
| 20p loss | 113 (22%) | 403 |
0.79 (0.862) |
0.621 (0.723) |
0.0232 (0.0528) |
0.0113 (0.0295) |
0.00698 (0.0196) |
0.0573 (0.11) |
0.00464 (0.0143) |
0.00078 (0.00303) |
1 (1.00) |
0.636 (0.735) |
0.0139 (0.0355) |
0.0234 (0.0533) |
| 5p gain | 279 (54%) | 237 |
0.481 (0.583) |
0.666 (0.761) |
1e-05 (8.2e-05) |
0.0599 (0.114) |
0.262 (0.371) |
0.0472 (0.0945) |
0.00032 (0.00142) |
0.00635 (0.0182) |
0.106 (0.183) |
0.116 (0.196) |
0.0472 (0.0945) |
0.00034 (0.00148) |
| 16p gain | 137 (27%) | 379 |
0.553 (0.657) |
0.337 (0.443) |
0.00023 (0.00108) |
0.673 (0.769) |
0.00342 (0.0112) |
0.135 (0.222) |
0.0206 (0.0486) |
0.00702 (0.0196) |
0.0302 (0.0658) |
0.00556 (0.0165) |
0.181 (0.28) |
0.345 (0.451) |
| 17p gain | 84 (16%) | 432 |
0.405 (0.511) |
0.314 (0.42) |
0.00268 (0.00912) |
0.0628 (0.119) |
0.119 (0.201) |
0.0159 (0.0395) |
0.0407 (0.0843) |
0.0225 (0.0519) |
0.00948 (0.0253) |
0.00015 (0.000745) |
0.0534 (0.104) |
0.158 (0.249) |
| 9q loss | 249 (48%) | 267 |
1 (1.00) |
0.902 (0.952) |
1e-05 (8.2e-05) |
0.0035 (0.0114) |
0.291 (0.4) |
0.106 (0.183) |
0.205 (0.307) |
0.00026 (0.00121) |
0.00448 (0.014) |
3e-05 (0.000198) |
0.0521 (0.102) |
0.0127 (0.0328) |
| 10p loss | 110 (21%) | 406 |
0.777 (0.857) |
0.786 (0.862) |
1e-05 (8.2e-05) |
0.169 (0.264) |
0.0483 (0.0958) |
0.888 (0.944) |
0.00112 (0.00421) |
1e-05 (8.2e-05) |
0.00757 (0.0208) |
0.0006 (0.00244) |
0.242 (0.348) |
0.235 (0.34) |
| 14q loss | 114 (22%) | 402 |
0.403 (0.51) |
0.409 (0.515) |
0.0003 (0.00135) |
0.0253 (0.0567) |
0.00222 (0.00777) |
0.181 (0.28) |
0.401 (0.509) |
0.00928 (0.0249) |
0.0155 (0.0388) |
0.0283 (0.0624) |
0.676 (0.771) |
0.319 (0.423) |
| 18p loss | 180 (35%) | 336 |
0.125 (0.209) |
0.236 (0.343) |
1e-05 (8.2e-05) |
0.946 (0.992) |
0.0451 (0.0912) |
0.00618 (0.0178) |
0.0016 (0.00575) |
0.00016 (0.000787) |
0.00413 (0.0131) |
0.489 (0.589) |
0.32 (0.423) |
0.191 (0.291) |
| 1p gain | 142 (28%) | 374 |
1 (1.00) |
1 (1.00) |
1e-05 (8.2e-05) |
0.789 (0.862) |
0.00034 (0.00148) |
0.0491 (0.0966) |
0.00151 (0.00546) |
0.0253 (0.0567) |
0.197 (0.299) |
0.17 (0.266) |
0.303 (0.411) |
0.153 (0.242) |
| 5q gain | 132 (26%) | 384 |
0.37 (0.477) |
0.33 (0.435) |
0.004 (0.0128) |
0.213 (0.315) |
0.0953 (0.167) |
0.00381 (0.0123) |
0.0229 (0.0526) |
0.046 (0.0926) |
0.185 (0.284) |
0.00651 (0.0185) |
0.0965 (0.169) |
0.375 (0.483) |
| 6p gain | 146 (28%) | 370 |
0.0825 (0.149) |
0.088 (0.156) |
0.00038 (0.00165) |
0.00011 (0.000576) |
0.32 (0.423) |
0.84 (0.905) |
0.044 (0.0895) |
0.0225 (0.0519) |
0.0763 (0.14) |
0.0297 (0.0651) |
0.0719 (0.133) |
0.0509 (0.0998) |
| 6q gain | 60 (12%) | 456 |
1 (1.00) |
1 (1.00) |
0.0157 (0.0391) |
0.0782 (0.143) |
0.0488 (0.0962) |
0.432 (0.536) |
0.211 (0.313) |
0.0168 (0.0412) |
0.0127 (0.0327) |
0.0314 (0.068) |
0.285 (0.393) |
0.151 (0.24) |
| 8p gain | 125 (24%) | 391 |
0.253 (0.361) |
0.253 (0.361) |
1e-05 (8.2e-05) |
0.0271 (0.0602) |
0.275 (0.383) |
0.887 (0.944) |
0.0168 (0.0412) |
0.00385 (0.0124) |
0.416 (0.522) |
0.707 (0.795) |
0.0343 (0.0728) |
0.838 (0.904) |
| 19q gain | 78 (15%) | 438 |
0.00082 (0.00316) |
0.00737 (0.0203) |
0.0418 (0.086) |
0.233 (0.339) |
0.127 (0.213) |
0.039 (0.0812) |
0.065 (0.122) |
0.135 (0.222) |
0.44 (0.544) |
0.0279 (0.0617) |
||
| 9p loss | 269 (52%) | 247 |
0.591 (0.696) |
0.601 (0.704) |
1e-05 (8.2e-05) |
0.00344 (0.0112) |
0.61 (0.713) |
0.399 (0.507) |
0.0882 (0.156) |
5e-05 (0.000296) |
0.051 (0.0998) |
0.0121 (0.0312) |
0.18 (0.279) |
0.0329 (0.0707) |
| 11q loss | 87 (17%) | 429 |
0.467 (0.57) |
0.482 (0.584) |
1e-05 (8.2e-05) |
0.0001 (0.000532) |
0.588 (0.692) |
0.125 (0.21) |
0.00138 (0.00505) |
0.00356 (0.0116) |
0.067 (0.126) |
0.0658 (0.124) |
0.00644 (0.0184) |
0.88 (0.94) |
| 4p gain | 83 (16%) | 433 |
1 (1.00) |
1 (1.00) |
3e-05 (0.000198) |
0.00376 (0.0122) |
0.498 (0.599) |
0.14 (0.228) |
0.00554 (0.0165) |
0.0477 (0.0953) |
0.0677 (0.127) |
0.128 (0.213) |
0.936 (0.982) |
0.134 (0.222) |
| 4q gain | 49 (9%) | 467 |
0.427 (0.532) |
0.37 (0.478) |
0.00073 (0.00287) |
0.712 (0.798) |
0.958 (1.00) |
0.0485 (0.0959) |
0.00887 (0.024) |
0.0216 (0.0505) |
0.0646 (0.122) |
0.13 (0.215) |
0.174 (0.271) |
0.338 (0.443) |
| 9p gain | 45 (9%) | 471 |
9e-05 (0.000487) |
0.0225 (0.0519) |
0.684 (0.777) |
0.257 (0.365) |
0.0115 (0.0299) |
0.00526 (0.0158) |
0.0795 (0.145) |
0.124 (0.208) |
0.8 (0.871) |
0.623 (0.723) |
||
| 15q gain | 38 (7%) | 478 |
0.2 (0.303) |
0.146 (0.235) |
0.00151 (0.00546) |
0.0146 (0.0368) |
0.659 (0.757) |
0.965 (1.00) |
1e-05 (8.2e-05) |
1e-05 (8.2e-05) |
0.837 (0.904) |
0.734 (0.818) |
0.193 (0.293) |
0.816 (0.886) |
| 21q gain | 98 (19%) | 418 |
0.31 (0.417) |
0.265 (0.374) |
1e-05 (8.2e-05) |
0.866 (0.928) |
0.033 (0.0707) |
0.326 (0.43) |
0.00456 (0.0142) |
0.00026 (0.00121) |
0.714 (0.799) |
0.878 (0.939) |
0.689 (0.78) |
0.275 (0.383) |
| 1q loss | 28 (5%) | 488 |
0.00569 (0.0168) |
0.00409 (0.013) |
0.0559 (0.108) |
0.0855 (0.153) |
0.0178 (0.0432) |
0.342 (0.447) |
0.594 (0.698) |
0.274 (0.383) |
0.0357 (0.0752) |
0.106 (0.183) |
||
| 3q loss | 144 (28%) | 372 |
0.228 (0.333) |
0.286 (0.394) |
1e-05 (8.2e-05) |
0.0394 (0.0819) |
0.318 (0.423) |
0.808 (0.878) |
0.314 (0.42) |
0.00538 (0.0161) |
0.46 (0.564) |
0.0225 (0.0519) |
0.194 (0.294) |
0.979 (1.00) |
| 6q loss | 217 (42%) | 299 |
0.43 (0.534) |
0.541 (0.643) |
0.215 (0.318) |
1e-05 (8.2e-05) |
0.455 (0.559) |
0.716 (0.8) |
0.267 (0.376) |
0.00014 (0.000706) |
0.563 (0.668) |
0.00081 (0.00314) |
0.212 (0.315) |
0.0206 (0.0486) |
| 7p loss | 34 (7%) | 482 |
1 (1.00) |
1 (1.00) |
0.00013 (0.000666) |
0.0443 (0.0899) |
0.772 (0.854) |
0.71 (0.797) |
0.00999 (0.0266) |
0.0001 (0.000532) |
0.147 (0.235) |
0.364 (0.471) |
0.132 (0.219) |
0.173 (0.271) |
| 12p loss | 109 (21%) | 407 |
1 (1.00) |
0.882 (0.941) |
1e-05 (8.2e-05) |
0.269 (0.379) |
0.00708 (0.0196) |
0.103 (0.18) |
0.00039 (0.00168) |
0.00011 (0.000576) |
0.0714 (0.133) |
0.18 (0.279) |
0.136 (0.223) |
0.184 (0.284) |
| 12q loss | 94 (18%) | 422 |
0.579 (0.685) |
0.428 (0.533) |
1e-05 (8.2e-05) |
0.118 (0.201) |
0.105 (0.182) |
0.149 (0.237) |
8e-05 (0.00044) |
0.00013 (0.000666) |
0.0941 (0.166) |
0.0214 (0.0503) |
0.188 (0.288) |
0.22 (0.324) |
| xp loss | 106 (21%) | 410 |
0.702 (0.79) |
0.893 (0.947) |
0.00904 (0.0243) |
0.043 (0.0879) |
0.00684 (0.0193) |
0.142 (0.23) |
0.0977 (0.171) |
0.00477 (0.0146) |
0.757 (0.839) |
0.452 (0.557) |
0.389 (0.497) |
0.661 (0.759) |
| 16q gain | 101 (20%) | 415 |
0.298 (0.406) |
0.31 (0.417) |
0.0165 (0.0408) |
0.338 (0.443) |
0.297 (0.406) |
0.425 (0.531) |
0.346 (0.451) |
0.203 (0.305) |
0.0152 (0.0382) |
0.0146 (0.0368) |
0.513 (0.615) |
0.486 (0.587) |
| xq gain | 86 (17%) | 430 |
0.394 (0.503) |
0.246 (0.353) |
0.00059 (0.00241) |
0.187 (0.286) |
0.921 (0.971) |
0.336 (0.442) |
0.0485 (0.0959) |
0.0169 (0.0414) |
0.17 (0.266) |
0.436 (0.54) |
0.389 (0.497) |
0.054 (0.104) |
| 9q gain | 34 (7%) | 482 |
0.0045 (0.014) |
0.106 (0.183) |
0.274 (0.383) |
0.138 (0.225) |
0.178 (0.277) |
0.0483 (0.0958) |
0.223 (0.326) |
0.889 (0.944) |
0.698 (0.787) |
0.312 (0.419) |
||
| 13q gain | 43 (8%) | 473 |
0.63 (0.732) |
0.539 (0.642) |
0.0554 (0.107) |
0.0143 (0.0362) |
0.0718 (0.133) |
0.723 (0.807) |
0.304 (0.412) |
0.0227 (0.0523) |
0.935 (0.981) |
0.162 (0.255) |
0.363 (0.471) |
0.483 (0.584) |
| xp gain | 53 (10%) | 463 |
0.293 (0.402) |
0.221 (0.324) |
0.0739 (0.136) |
0.00635 (0.0182) |
0.363 (0.471) |
0.827 (0.895) |
0.149 (0.237) |
0.124 (0.208) |
0.0837 (0.15) |
0.332 (0.437) |
0.0446 (0.0904) |
0.191 (0.291) |
| 8q loss | 56 (11%) | 460 |
1 (1.00) |
0.583 (0.687) |
1e-05 (8.2e-05) |
0.418 (0.523) |
0.088 (0.156) |
0.103 (0.18) |
0.0738 (0.136) |
0.0412 (0.0851) |
0.662 (0.76) |
0.652 (0.752) |
0.824 (0.893) |
0.263 (0.372) |
| 22q gain | 62 (12%) | 454 |
0.11 (0.188) |
0.122 (0.206) |
0.0522 (0.102) |
0.678 (0.772) |
0.858 (0.92) |
0.144 (0.232) |
0.226 (0.329) |
0.0426 (0.0871) |
0.613 (0.716) |
0.835 (0.903) |
0.372 (0.479) |
0.276 (0.385) |
| 2p loss | 24 (5%) | 492 |
0.427 (0.532) |
0.581 (0.686) |
0.666 (0.761) |
0.889 (0.944) |
1 (1.00) |
0.297 (0.406) |
0.998 (1.00) |
0.751 (0.833) |
0.039 (0.0812) |
0.923 (0.971) |
0.142 (0.23) |
0.462 (0.566) |
| 6p loss | 101 (20%) | 415 |
0.0635 (0.12) |
0.0935 (0.165) |
0.0582 (0.111) |
0.00398 (0.0128) |
0.788 (0.862) |
0.467 (0.57) |
0.452 (0.557) |
0.278 (0.386) |
0.146 (0.235) |
0.0975 (0.171) |
0.205 (0.307) |
0.156 (0.246) |
| 7q loss | 41 (8%) | 475 |
0.255 (0.363) |
0.256 (0.364) |
0.0194 (0.0463) |
0.273 (0.383) |
0.78 (0.858) |
0.6 (0.704) |
0.309 (0.417) |
0.091 (0.161) |
0.473 (0.575) |
0.149 (0.237) |
0.788 (0.862) |
0.732 (0.816) |
| 17q loss | 60 (12%) | 456 |
0.52 (0.622) |
0.844 (0.907) |
0.00053 (0.00218) |
0.378 (0.485) |
0.115 (0.195) |
0.773 (0.855) |
0.3 (0.409) |
0.277 (0.385) |
0.602 (0.705) |
0.137 (0.223) |
0.396 (0.504) |
0.471 (0.574) |
| xq loss | 61 (12%) | 455 |
0.0827 (0.149) |
0.054 (0.104) |
0.203 (0.305) |
0.0056 (0.0165) |
0.256 (0.363) |
0.697 (0.787) |
0.187 (0.286) |
0.157 (0.248) |
0.0718 (0.133) |
0.051 (0.0998) |
0.155 (0.246) |
0.303 (0.411) |
| 19p gain | 33 (6%) | 483 |
0.0642 (0.122) |
0.73 (0.815) |
0.275 (0.383) |
0.663 (0.76) |
0.898 (0.951) |
0.707 (0.795) |
0.505 (0.607) |
0.658 (0.757) |
0.886 (0.944) |
0.513 (0.615) |
||
| 2q loss | 25 (5%) | 491 |
1 (1.00) |
1 (1.00) |
0.212 (0.315) |
0.242 (0.348) |
0.777 (0.857) |
0.271 (0.381) |
0.213 (0.315) |
0.44 (0.545) |
0.21 (0.312) |
0.923 (0.971) |
0.31 (0.417) |
0.285 (0.394) |
| 20q loss | 67 (13%) | 449 |
1 (1.00) |
1 (1.00) |
0.986 (1.00) |
0.69 (0.78) |
0.126 (0.21) |
0.282 (0.391) |
0.871 (0.933) |
0.105 (0.183) |
0.739 (0.821) |
0.807 (0.878) |
0.123 (0.207) |
0.655 (0.755) |
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S1. Gene #1: '1p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 1P GAIN MUTATED | 81 | 28 | 18 | 15 |
| 1P GAIN WILD-TYPE | 91 | 110 | 114 | 59 |
Figure S1. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0015
Table S2. Gene #1: '1p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 1P GAIN MUTATED | 42 | 6 | 17 | 18 | 19 |
| 1P GAIN WILD-TYPE | 49 | 16 | 49 | 57 | 90 |
Figure S2. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0491 (Fisher's exact test), Q value = 0.097
Table S3. Gene #1: '1p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 1P GAIN MUTATED | 50 | 42 | 10 |
| 1P GAIN WILD-TYPE | 117 | 91 | 53 |
Figure S3. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00151 (Fisher's exact test), Q value = 0.0055
Table S4. Gene #1: '1p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 1P GAIN MUTATED | 53 | 31 | 15 | 29 | 13 |
| 1P GAIN WILD-TYPE | 77 | 88 | 75 | 86 | 45 |
Figure S4. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0253 (Fisher's exact test), Q value = 0.057
Table S5. Gene #1: '1p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 1P GAIN MUTATED | 20 | 37 | 37 | 7 | 10 | 12 | 18 |
| 1P GAIN WILD-TYPE | 58 | 73 | 60 | 41 | 43 | 37 | 59 |
Figure S5. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S6. Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 1Q GAIN MUTATED | 123 | 83 | 60 | 53 |
| 1Q GAIN WILD-TYPE | 49 | 55 | 72 | 21 |
Figure S6. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00103 (Fisher's exact test), Q value = 0.0039
Table S7. Gene #2: '1q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 1Q GAIN MUTATED | 103 | 118 | 63 |
| 1Q GAIN WILD-TYPE | 53 | 52 | 66 |
Figure S7. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 3e-04
Table S8. Gene #2: '1q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 1Q GAIN MUTATED | 64 | 16 | 53 | 39 | 53 |
| 1Q GAIN WILD-TYPE | 27 | 6 | 13 | 36 | 56 |
Figure S8. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00282 (Fisher's exact test), Q value = 0.0095
Table S9. Gene #2: '1q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 1Q GAIN MUTATED | 119 | 72 | 34 |
| 1Q GAIN WILD-TYPE | 48 | 61 | 29 |
Figure S9. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00187 (Fisher's exact test), Q value = 0.0066
Table S10. Gene #2: '1q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 1Q GAIN MUTATED | 88 | 77 | 40 | 79 | 32 |
| 1Q GAIN WILD-TYPE | 42 | 42 | 50 | 36 | 26 |
Figure S10. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0264 (Fisher's exact test), Q value = 0.059
Table S11. Gene #2: '1q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 1Q GAIN MUTATED | 49 | 67 | 52 | 37 | 40 | 30 | 41 |
| 1Q GAIN WILD-TYPE | 29 | 43 | 45 | 11 | 13 | 19 | 36 |
Figure S11. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S12. Gene #2: '1q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 1Q GAIN MUTATED | 53 | 35 | 92 | 67 | 56 | 12 |
| 1Q GAIN WILD-TYPE | 18 | 4 | 53 | 63 | 40 | 17 |
Figure S12. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S13. Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 2P GAIN MUTATED | 53 | 59 | 15 | 27 |
| 2P GAIN WILD-TYPE | 119 | 79 | 117 | 47 |
Figure S13. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 2e-04
Table S14. Gene #3: '2p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 2P GAIN MUTATED | 64 | 47 | 20 |
| 2P GAIN WILD-TYPE | 92 | 123 | 109 |
Figure S14. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00024
Table S15. Gene #3: '2p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 2P GAIN MUTATED | 43 | 17 | 28 | 50 | 16 |
| 2P GAIN WILD-TYPE | 87 | 102 | 62 | 65 | 42 |
Figure S15. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00019 (Fisher's exact test), Q value = 0.00091
Table S16. Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 2P GAIN MUTATED | 15 | 32 | 35 | 8 | 25 | 23 | 16 |
| 2P GAIN WILD-TYPE | 63 | 78 | 62 | 40 | 28 | 26 | 61 |
Figure S16. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S17. Gene #3: '2p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 2P GAIN MUTATED | 37 | 92 | 24 |
| 2P GAIN WILD-TYPE | 149 | 129 | 79 |
Figure S17. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00045 (Fisher's exact test), Q value = 0.0019
Table S18. Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 2P GAIN MUTATED | 13 | 17 | 51 | 29 | 39 | 4 |
| 2P GAIN WILD-TYPE | 58 | 22 | 94 | 101 | 57 | 25 |
Figure S18. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0012 (Fisher's exact test), Q value = 0.0044
Table S19. Gene #3: '2p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 2P GAIN MUTATED | 8 | 41 | 27 | 9 | 18 | 23 |
| 2P GAIN WILD-TYPE | 51 | 49 | 68 | 34 | 52 | 54 |
Figure S19. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00039
Table S20. Gene #3: '2p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 2P GAIN MUTATED | 15 | 88 | 23 |
| 2P GAIN WILD-TYPE | 89 | 150 | 69 |
Figure S20. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S21. Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 2Q GAIN MUTATED | 50 | 49 | 15 | 29 |
| 2Q GAIN WILD-TYPE | 122 | 89 | 117 | 45 |
Figure S21. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00029 (Fisher's exact test), Q value = 0.0013
Table S22. Gene #4: '2q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 2Q GAIN MUTATED | 57 | 46 | 20 |
| 2Q GAIN WILD-TYPE | 99 | 124 | 109 |
Figure S22. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0297 (Fisher's exact test), Q value = 0.065
Table S23. Gene #4: '2q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 2Q GAIN MUTATED | 37 | 22 | 26 | 43 | 15 |
| 2Q GAIN WILD-TYPE | 93 | 97 | 64 | 72 | 43 |
Figure S23. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0115 (Fisher's exact test), Q value = 0.03
Table S24. Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 2Q GAIN MUTATED | 14 | 30 | 34 | 12 | 18 | 21 | 14 |
| 2Q GAIN WILD-TYPE | 64 | 80 | 63 | 36 | 35 | 28 | 63 |
Figure S24. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0013 (Fisher's exact test), Q value = 0.0048
Table S25. Gene #4: '2q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 2Q GAIN MUTATED | 39 | 80 | 23 |
| 2Q GAIN WILD-TYPE | 147 | 141 | 80 |
Figure S25. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0139 (Fisher's exact test), Q value = 0.035
Table S26. Gene #4: '2q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 2Q GAIN MUTATED | 13 | 13 | 48 | 31 | 34 | 3 |
| 2Q GAIN WILD-TYPE | 58 | 26 | 97 | 99 | 62 | 26 |
Figure S26. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00557 (Fisher's exact test), Q value = 0.017
Table S27. Gene #4: '2q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 2Q GAIN MUTATED | 8 | 36 | 28 | 7 | 16 | 20 |
| 2Q GAIN WILD-TYPE | 51 | 54 | 67 | 36 | 54 | 57 |
Figure S27. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00479 (Fisher's exact test), Q value = 0.015
Table S28. Gene #4: '2q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 2Q GAIN MUTATED | 16 | 76 | 23 |
| 2Q GAIN WILD-TYPE | 88 | 162 | 69 |
Figure S28. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00827 (Fisher's exact test), Q value = 0.023
Table S29. Gene #5: '3p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 3P GAIN MUTATED | 16 | 17 | 3 | 8 |
| 3P GAIN WILD-TYPE | 156 | 121 | 129 | 66 |
Figure S29. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00069 (Fisher's exact test), Q value = 0.0027
Table S30. Gene #5: '3p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 3P GAIN MUTATED | 18 | 20 | 2 |
| 3P GAIN WILD-TYPE | 138 | 150 | 127 |
Figure S30. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0216 (Fisher's exact test), Q value = 0.05
Table S31. Gene #5: '3p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 3P GAIN MUTATED | 7 | 3 | 5 | 13 | 4 |
| 3P GAIN WILD-TYPE | 84 | 19 | 61 | 62 | 105 |
Figure S31. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 2e-04
Table S32. Gene #5: '3p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 3P GAIN MUTATED | 19 | 0 | 8 | 14 | 3 |
| 3P GAIN WILD-TYPE | 111 | 119 | 82 | 101 | 55 |
Figure S32. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00093 (Fisher's exact test), Q value = 0.0036
Table S33. Gene #5: '3p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 3P GAIN MUTATED | 3 | 13 | 19 | 3 | 2 | 2 | 2 |
| 3P GAIN WILD-TYPE | 75 | 97 | 78 | 45 | 51 | 47 | 75 |
Figure S33. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00239 (Fisher's exact test), Q value = 0.0083
Table S34. Gene #5: '3p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 3P GAIN MUTATED | 0 | 6 | 16 | 1 | 8 | 8 |
| 3P GAIN WILD-TYPE | 59 | 84 | 79 | 42 | 62 | 69 |
Figure S34. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0131 (Fisher's exact test), Q value = 0.034
Table S35. Gene #5: '3p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 3P GAIN MUTATED | 3 | 23 | 13 |
| 3P GAIN WILD-TYPE | 101 | 215 | 79 |
Figure S35. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 2e-04
Table S36. Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 3Q GAIN MUTATED | 30 | 40 | 9 | 11 |
| 3Q GAIN WILD-TYPE | 142 | 98 | 123 | 63 |
Figure S36. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00057 (Fisher's exact test), Q value = 0.0023
Table S37. Gene #6: '3q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 3Q GAIN MUTATED | 40 | 31 | 11 |
| 3Q GAIN WILD-TYPE | 116 | 139 | 118 |
Figure S37. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0166 (Fisher's exact test), Q value = 0.041
Table S38. Gene #6: '3q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 3Q GAIN MUTATED | 15 | 5 | 10 | 23 | 12 |
| 3Q GAIN WILD-TYPE | 76 | 17 | 56 | 52 | 97 |
Figure S38. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S39. Gene #6: '3q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 3Q GAIN MUTATED | 31 | 3 | 23 | 26 | 7 |
| 3Q GAIN WILD-TYPE | 99 | 116 | 67 | 89 | 51 |
Figure S39. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S40. Gene #6: '3q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 3Q GAIN MUTATED | 4 | 24 | 39 | 3 | 6 | 8 | 6 |
| 3Q GAIN WILD-TYPE | 74 | 86 | 58 | 45 | 47 | 41 | 71 |
Figure S40. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0179 (Fisher's exact test), Q value = 0.043
Table S41. Gene #6: '3q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 3Q GAIN MUTATED | 27 | 51 | 12 |
| 3Q GAIN WILD-TYPE | 159 | 170 | 91 |
Figure S41. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00064 (Fisher's exact test), Q value = 0.0026
Table S42. Gene #6: '3q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 3Q GAIN MUTATED | 2 | 18 | 27 | 3 | 15 | 14 |
| 3Q GAIN WILD-TYPE | 57 | 72 | 68 | 40 | 55 | 63 |
Figure S42. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.027 (Fisher's exact test), Q value = 0.06
Table S43. Gene #6: '3q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 3Q GAIN MUTATED | 10 | 50 | 19 |
| 3Q GAIN WILD-TYPE | 94 | 188 | 73 |
Figure S43. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 2e-04
Table S44. Gene #7: '4p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 4P GAIN MUTATED | 40 | 29 | 8 | 6 |
| 4P GAIN WILD-TYPE | 132 | 109 | 124 | 68 |
Figure S44. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00376 (Fisher's exact test), Q value = 0.012
Table S45. Gene #7: '4p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 4P GAIN MUTATED | 36 | 28 | 11 |
| 4P GAIN WILD-TYPE | 120 | 142 | 118 |
Figure S45. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00554 (Fisher's exact test), Q value = 0.017
Table S46. Gene #7: '4p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 4P GAIN MUTATED | 32 | 9 | 15 | 20 | 7 |
| 4P GAIN WILD-TYPE | 98 | 110 | 75 | 95 | 51 |
Figure S46. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0477 (Fisher's exact test), Q value = 0.095
Table S47. Gene #7: '4p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 4P GAIN MUTATED | 6 | 24 | 19 | 6 | 8 | 12 | 8 |
| 4P GAIN WILD-TYPE | 72 | 86 | 78 | 42 | 45 | 37 | 69 |
Figure S47. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00073 (Fisher's exact test), Q value = 0.0029
Table S48. Gene #8: '4q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 4Q GAIN MUTATED | 27 | 14 | 7 | 1 |
| 4Q GAIN WILD-TYPE | 145 | 124 | 125 | 73 |
Figure S48. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0485 (Fisher's exact test), Q value = 0.096
Table S49. Gene #8: '4q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 4Q GAIN MUTATED | 9 | 18 | 5 |
| 4Q GAIN WILD-TYPE | 158 | 115 | 58 |
Figure S49. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00887 (Fisher's exact test), Q value = 0.024
Table S50. Gene #8: '4q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 4Q GAIN MUTATED | 23 | 6 | 7 | 7 | 6 |
| 4Q GAIN WILD-TYPE | 107 | 113 | 83 | 108 | 52 |
Figure S50. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0216 (Fisher's exact test), Q value = 0.05
Table S51. Gene #8: '4q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 4Q GAIN MUTATED | 5 | 17 | 15 | 1 | 2 | 4 | 5 |
| 4Q GAIN WILD-TYPE | 73 | 93 | 82 | 47 | 51 | 45 | 72 |
Figure S51. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S52. Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 5P GAIN MUTATED | 135 | 60 | 39 | 45 |
| 5P GAIN WILD-TYPE | 37 | 78 | 93 | 29 |
Figure S52. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0472 (Fisher's exact test), Q value = 0.094
Table S53. Gene #9: '5p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 5P GAIN MUTATED | 93 | 64 | 42 |
| 5P GAIN WILD-TYPE | 74 | 69 | 21 |
Figure S53. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00032 (Fisher's exact test), Q value = 0.0014
Table S54. Gene #9: '5p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 5P GAIN MUTATED | 87 | 55 | 35 | 66 | 34 |
| 5P GAIN WILD-TYPE | 43 | 64 | 55 | 49 | 24 |
Figure S54. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00635 (Fisher's exact test), Q value = 0.018
Table S55. Gene #9: '5p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 5P GAIN MUTATED | 42 | 69 | 59 | 16 | 32 | 26 | 33 |
| 5P GAIN WILD-TYPE | 36 | 41 | 38 | 32 | 21 | 23 | 44 |
Figure S55. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0472 (Fisher's exact test), Q value = 0.094
Table S56. Gene #9: '5p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 5P GAIN MUTATED | 24 | 60 | 52 | 22 | 35 | 45 |
| 5P GAIN WILD-TYPE | 35 | 30 | 43 | 21 | 35 | 32 |
Figure S56. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0015
Table S57. Gene #9: '5p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 5P GAIN MUTATED | 40 | 148 | 50 |
| 5P GAIN WILD-TYPE | 64 | 90 | 42 |
Figure S57. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.004 (Fisher's exact test), Q value = 0.013
Table S58. Gene #10: '5q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 5Q GAIN MUTATED | 60 | 24 | 32 | 16 |
| 5Q GAIN WILD-TYPE | 112 | 114 | 100 | 58 |
Figure S58. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00381 (Fisher's exact test), Q value = 0.012
Table S59. Gene #10: '5q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 5Q GAIN MUTATED | 49 | 22 | 23 |
| 5Q GAIN WILD-TYPE | 118 | 111 | 40 |
Figure S59. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0229 (Fisher's exact test), Q value = 0.053
Table S60. Gene #10: '5q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 5Q GAIN MUTATED | 31 | 41 | 16 | 23 | 19 |
| 5Q GAIN WILD-TYPE | 99 | 78 | 74 | 92 | 39 |
Figure S60. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.046 (Fisher's exact test), Q value = 0.093
Table S61. Gene #10: '5q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 5Q GAIN MUTATED | 32 | 24 | 27 | 10 | 12 | 10 | 15 |
| 5Q GAIN WILD-TYPE | 46 | 86 | 70 | 38 | 41 | 39 | 62 |
Figure S61. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00651 (Fisher's exact test), Q value = 0.019
Table S62. Gene #10: '5q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 5Q GAIN MUTATED | 27 | 10 | 26 | 37 | 19 | 12 |
| 5Q GAIN WILD-TYPE | 44 | 29 | 119 | 93 | 77 | 17 |
Figure S62. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00038 (Fisher's exact test), Q value = 0.0016
Table S63. Gene #11: '6p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 6P GAIN MUTATED | 54 | 36 | 23 | 33 |
| 6P GAIN WILD-TYPE | 118 | 102 | 109 | 41 |
Figure S63. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00058
Table S64. Gene #11: '6p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 6P GAIN MUTATED | 60 | 46 | 21 |
| 6P GAIN WILD-TYPE | 96 | 124 | 108 |
Figure S64. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.044 (Fisher's exact test), Q value = 0.089
Table S65. Gene #11: '6p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 6P GAIN MUTATED | 38 | 31 | 17 | 44 | 16 |
| 6P GAIN WILD-TYPE | 92 | 88 | 73 | 71 | 42 |
Figure S65. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0225 (Fisher's exact test), Q value = 0.052
Table S66. Gene #11: '6p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 6P GAIN MUTATED | 17 | 26 | 39 | 18 | 17 | 14 | 15 |
| 6P GAIN WILD-TYPE | 61 | 84 | 58 | 30 | 36 | 35 | 62 |
Figure S66. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0297 (Fisher's exact test), Q value = 0.065
Table S67. Gene #11: '6p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 6P GAIN MUTATED | 16 | 12 | 49 | 24 | 34 | 8 |
| 6P GAIN WILD-TYPE | 55 | 27 | 96 | 106 | 62 | 21 |
Figure S67. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0157 (Fisher's exact test), Q value = 0.039
Table S68. Gene #12: '6q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 6Q GAIN MUTATED | 23 | 21 | 6 | 10 |
| 6Q GAIN WILD-TYPE | 149 | 117 | 126 | 64 |
Figure S68. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0488 (Fisher's exact test), Q value = 0.096
Table S69. Gene #12: '6q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 6Q GAIN MUTATED | 5 | 2 | 11 | 14 | 10 |
| 6Q GAIN WILD-TYPE | 86 | 20 | 55 | 61 | 99 |
Figure S69. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0168 (Fisher's exact test), Q value = 0.041
Table S70. Gene #12: '6q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 6Q GAIN MUTATED | 11 | 7 | 21 | 5 | 6 | 6 | 4 |
| 6Q GAIN WILD-TYPE | 67 | 103 | 76 | 43 | 47 | 43 | 73 |
Figure S70. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0127 (Fisher's exact test), Q value = 0.033
Table S71. Gene #12: '6q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 6Q GAIN MUTATED | 13 | 36 | 10 |
| 6Q GAIN WILD-TYPE | 173 | 185 | 93 |
Figure S71. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0314 (Fisher's exact test), Q value = 0.068
Table S72. Gene #12: '6q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 6Q GAIN MUTATED | 3 | 6 | 22 | 9 | 16 | 3 |
| 6Q GAIN WILD-TYPE | 68 | 33 | 123 | 121 | 80 | 26 |
Figure S72. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S73. Gene #13: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 7P GAIN MUTATED | 138 | 82 | 19 | 28 |
| 7P GAIN WILD-TYPE | 34 | 56 | 113 | 46 |
Figure S73. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00434 (Fisher's exact test), Q value = 0.014
Table S74. Gene #13: '7p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 7P GAIN MUTATED | 59 | 11 | 26 | 47 | 50 |
| 7P GAIN WILD-TYPE | 32 | 11 | 40 | 28 | 59 |
Figure S74. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00577 (Fisher's exact test), Q value = 0.017
Table S75. Gene #13: '7p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 7P GAIN MUTATED | 81 | 85 | 27 |
| 7P GAIN WILD-TYPE | 86 | 48 | 36 |
Figure S75. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S76. Gene #13: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 7P GAIN MUTATED | 101 | 34 | 47 | 51 | 30 |
| 7P GAIN WILD-TYPE | 29 | 85 | 43 | 64 | 28 |
Figure S76. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S77. Gene #13: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 7P GAIN MUTATED | 31 | 80 | 60 | 9 | 22 | 28 | 33 |
| 7P GAIN WILD-TYPE | 47 | 30 | 37 | 39 | 31 | 21 | 44 |
Figure S77. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S78. Gene #13: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 7P GAIN MUTATED | 71 | 125 | 67 |
| 7P GAIN WILD-TYPE | 115 | 96 | 36 |
Figure S78. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S79. Gene #13: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 7P GAIN MUTATED | 20 | 18 | 95 | 56 | 56 | 18 |
| 7P GAIN WILD-TYPE | 51 | 21 | 50 | 74 | 40 | 11 |
Figure S79. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00293 (Fisher's exact test), Q value = 0.0098
Table S80. Gene #13: '7p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 7P GAIN MUTATED | 17 | 48 | 52 | 25 | 36 | 49 |
| 7P GAIN WILD-TYPE | 42 | 42 | 43 | 18 | 34 | 28 |
Figure S80. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S81. Gene #13: '7p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 7P GAIN MUTATED | 31 | 138 | 58 |
| 7P GAIN WILD-TYPE | 73 | 100 | 34 |
Figure S81. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S82. Gene #14: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 7Q GAIN MUTATED | 113 | 66 | 17 | 24 |
| 7Q GAIN WILD-TYPE | 59 | 72 | 115 | 50 |
Figure S82. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S83. Gene #14: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 7Q GAIN MUTATED | 87 | 28 | 40 | 35 | 26 |
| 7Q GAIN WILD-TYPE | 43 | 91 | 50 | 80 | 32 |
Figure S83. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S84. Gene #14: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 7Q GAIN MUTATED | 25 | 72 | 45 | 7 | 17 | 23 | 27 |
| 7Q GAIN WILD-TYPE | 53 | 38 | 52 | 41 | 36 | 26 | 50 |
Figure S84. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00402 (Fisher's exact test), Q value = 0.013
Table S85. Gene #14: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 7Q GAIN MUTATED | 61 | 106 | 49 |
| 7Q GAIN WILD-TYPE | 125 | 115 | 54 |
Figure S85. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00119 (Fisher's exact test), Q value = 0.0044
Table S86. Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 7Q GAIN MUTATED | 17 | 18 | 75 | 46 | 45 | 15 |
| 7Q GAIN WILD-TYPE | 54 | 21 | 70 | 84 | 51 | 14 |
Figure S86. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.048 (Fisher's exact test), Q value = 0.096
Table S87. Gene #14: '7q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 7Q GAIN MUTATED | 16 | 35 | 44 | 21 | 26 | 40 |
| 7Q GAIN WILD-TYPE | 43 | 55 | 51 | 22 | 44 | 37 |
Figure S87. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 2e-04
Table S88. Gene #14: '7q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 7Q GAIN MUTATED | 23 | 112 | 47 |
| 7Q GAIN WILD-TYPE | 81 | 126 | 45 |
Figure S88. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S89. Gene #15: '8p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 8P GAIN MUTATED | 34 | 36 | 17 | 38 |
| 8P GAIN WILD-TYPE | 138 | 102 | 115 | 36 |
Figure S89. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0271 (Fisher's exact test), Q value = 0.06
Table S90. Gene #15: '8p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 8P GAIN MUTATED | 48 | 41 | 22 |
| 8P GAIN WILD-TYPE | 108 | 129 | 107 |
Figure S90. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0168 (Fisher's exact test), Q value = 0.041
Table S91. Gene #15: '8p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 8P GAIN MUTATED | 29 | 20 | 19 | 41 | 14 |
| 8P GAIN WILD-TYPE | 101 | 99 | 71 | 74 | 44 |
Figure S91. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00385 (Fisher's exact test), Q value = 0.012
Table S92. Gene #15: '8p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 8P GAIN MUTATED | 13 | 24 | 20 | 14 | 24 | 15 | 13 |
| 8P GAIN WILD-TYPE | 65 | 86 | 77 | 34 | 29 | 34 | 64 |
Figure S92. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0343 (Fisher's exact test), Q value = 0.073
Table S93. Gene #15: '8p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 8P GAIN MUTATED | 8 | 31 | 27 | 7 | 18 | 15 |
| 8P GAIN WILD-TYPE | 51 | 59 | 68 | 36 | 52 | 62 |
Figure S93. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0376 (Fisher's exact test), Q value = 0.079
Table S94. Gene #16: '8q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 15 | 10 | 7 |
| 8Q GAIN MUTATED | 4 | 5 | 6 |
| 8Q GAIN WILD-TYPE | 11 | 5 | 1 |
Figure S94. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0438 (Fisher's exact test), Q value = 0.089
Table S95. Gene #16: '8q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 8Q GAIN MUTATED | 4 | 5 | 6 |
| 8Q GAIN WILD-TYPE | 10 | 6 | 1 |
Figure S95. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S96. Gene #16: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 8Q GAIN MUTATED | 75 | 82 | 28 | 60 |
| 8Q GAIN WILD-TYPE | 97 | 56 | 104 | 14 |
Figure S96. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S97. Gene #16: '8q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 8Q GAIN MUTATED | 88 | 91 | 39 |
| 8Q GAIN WILD-TYPE | 68 | 79 | 90 |
Figure S97. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S98. Gene #16: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 8Q GAIN MUTATED | 65 | 35 | 39 | 78 | 24 |
| 8Q GAIN WILD-TYPE | 65 | 84 | 51 | 37 | 34 |
Figure S98. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S99. Gene #16: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 8Q GAIN MUTATED | 28 | 54 | 49 | 20 | 42 | 26 | 22 |
| 8Q GAIN WILD-TYPE | 50 | 56 | 48 | 28 | 11 | 23 | 55 |
Figure S99. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S100. Gene #16: '8q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 8Q GAIN MUTATED | 60 | 126 | 56 |
| 8Q GAIN WILD-TYPE | 126 | 95 | 47 |
Figure S100. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00034
Table S101. Gene #16: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 8Q GAIN MUTATED | 25 | 29 | 77 | 47 | 53 | 11 |
| 8Q GAIN WILD-TYPE | 46 | 10 | 68 | 83 | 43 | 18 |
Figure S101. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S102. Gene #16: '8q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 8Q GAIN MUTATED | 13 | 58 | 45 | 17 | 38 | 38 |
| 8Q GAIN WILD-TYPE | 46 | 32 | 50 | 26 | 32 | 39 |
Figure S102. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00033 (Fisher's exact test), Q value = 0.0015
Table S103. Gene #16: '8q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 8Q GAIN MUTATED | 34 | 133 | 42 |
| 8Q GAIN WILD-TYPE | 70 | 105 | 50 |
Figure S103. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 0.00049
Table S104. Gene #17: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 9P GAIN MUTATED | 19 | 8 | 3 | 15 |
| 9P GAIN WILD-TYPE | 153 | 130 | 129 | 59 |
Figure S104. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0225 (Fisher's exact test), Q value = 0.052
Table S105. Gene #17: '9p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 9P GAIN MUTATED | 20 | 18 | 5 |
| 9P GAIN WILD-TYPE | 136 | 152 | 124 |
Figure S105. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0115 (Fisher's exact test), Q value = 0.03
Table S106. Gene #17: '9p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 9P GAIN MUTATED | 12 | 5 | 3 | 17 | 7 |
| 9P GAIN WILD-TYPE | 118 | 114 | 87 | 98 | 51 |
Figure S106. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00526 (Fisher's exact test), Q value = 0.016
Table S107. Gene #17: '9p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 9P GAIN MUTATED | 1 | 11 | 13 | 2 | 9 | 1 | 7 |
| 9P GAIN WILD-TYPE | 77 | 99 | 84 | 46 | 44 | 48 | 70 |
Figure S107. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0045 (Fisher's exact test), Q value = 0.014
Table S108. Gene #18: '9q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 9Q GAIN MUTATED | 14 | 8 | 2 | 10 |
| 9Q GAIN WILD-TYPE | 158 | 130 | 130 | 64 |
Figure S108. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0483 (Fisher's exact test), Q value = 0.096
Table S109. Gene #18: '9q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 9Q GAIN MUTATED | 1 | 7 | 12 | 2 | 6 | 2 | 3 |
| 9Q GAIN WILD-TYPE | 77 | 103 | 85 | 46 | 47 | 47 | 74 |
Figure S109. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S110. Gene #19: '10p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 10P GAIN MUTATED | 31 | 44 | 9 | 28 |
| 10P GAIN WILD-TYPE | 141 | 94 | 123 | 46 |
Figure S110. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S111. Gene #19: '10p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 10P GAIN MUTATED | 45 | 47 | 9 |
| 10P GAIN WILD-TYPE | 111 | 123 | 120 |
Figure S111. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00465 (Fisher's exact test), Q value = 0.014
Table S112. Gene #19: '10p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 10P GAIN MUTATED | 11 | 2 | 19 | 22 | 33 |
| 10P GAIN WILD-TYPE | 80 | 20 | 47 | 53 | 76 |
Figure S112. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0207 (Fisher's exact test), Q value = 0.049
Table S113. Gene #19: '10p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 10P GAIN MUTATED | 30 | 35 | 22 |
| 10P GAIN WILD-TYPE | 137 | 98 | 41 |
Figure S113. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S114. Gene #19: '10p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 10P GAIN MUTATED | 27 | 10 | 22 | 43 | 9 |
| 10P GAIN WILD-TYPE | 103 | 109 | 68 | 72 | 49 |
Figure S114. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S115. Gene #19: '10p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 10P GAIN MUTATED | 5 | 19 | 20 | 14 | 26 | 17 | 10 |
| 10P GAIN WILD-TYPE | 73 | 91 | 77 | 34 | 27 | 32 | 67 |
Figure S115. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00027 (Fisher's exact test), Q value = 0.0013
Table S116. Gene #19: '10p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 10P GAIN MUTATED | 24 | 65 | 21 |
| 10P GAIN WILD-TYPE | 162 | 156 | 82 |
Figure S116. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S117. Gene #19: '10p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 10P GAIN MUTATED | 12 | 15 | 44 | 12 | 25 | 2 |
| 10P GAIN WILD-TYPE | 59 | 24 | 101 | 118 | 71 | 27 |
Figure S117. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00084 (Fisher's exact test), Q value = 0.0032
Table S118. Gene #19: '10p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 10P GAIN MUTATED | 4 | 32 | 26 | 10 | 12 | 15 |
| 10P GAIN WILD-TYPE | 55 | 58 | 69 | 33 | 58 | 62 |
Figure S118. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00028 (Fisher's exact test), Q value = 0.0013
Table S119. Gene #19: '10p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 10P GAIN MUTATED | 10 | 69 | 20 |
| 10P GAIN WILD-TYPE | 94 | 169 | 72 |
Figure S119. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00051 (Fisher's exact test), Q value = 0.0021
Table S120. Gene #20: '10q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 10Q GAIN MUTATED | 24 | 29 | 8 | 18 |
| 10Q GAIN WILD-TYPE | 148 | 109 | 124 | 56 |
Figure S120. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00032 (Fisher's exact test), Q value = 0.0014
Table S121. Gene #20: '10q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 10Q GAIN MUTATED | 30 | 34 | 7 |
| 10Q GAIN WILD-TYPE | 126 | 136 | 122 |
Figure S121. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0459 (Fisher's exact test), Q value = 0.093
Table S122. Gene #20: '10q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 10Q GAIN MUTATED | 8 | 1 | 16 | 13 | 20 |
| 10Q GAIN WILD-TYPE | 83 | 21 | 50 | 62 | 89 |
Figure S122. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00076 (Fisher's exact test), Q value = 0.003
Table S123. Gene #20: '10q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 10Q GAIN MUTATED | 17 | 8 | 17 | 30 | 6 |
| 10Q GAIN WILD-TYPE | 113 | 111 | 73 | 85 | 52 |
Figure S123. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S124. Gene #20: '10q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 10Q GAIN MUTATED | 3 | 15 | 8 | 13 | 19 | 13 | 7 |
| 10Q GAIN WILD-TYPE | 75 | 95 | 89 | 35 | 34 | 36 | 70 |
Figure S124. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00543 (Fisher's exact test), Q value = 0.016
Table S125. Gene #20: '10q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 10Q GAIN MUTATED | 10 | 12 | 29 | 12 | 13 | 1 |
| 10Q GAIN WILD-TYPE | 61 | 27 | 116 | 118 | 83 | 28 |
Figure S125. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0241 (Fisher's exact test), Q value = 0.055
Table S126. Gene #20: '10q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 10Q GAIN MUTATED | 3 | 21 | 18 | 9 | 7 | 12 |
| 10Q GAIN WILD-TYPE | 56 | 69 | 77 | 34 | 63 | 65 |
Figure S126. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0174 (Fisher's exact test), Q value = 0.042
Table S127. Gene #20: '10q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 10Q GAIN MUTATED | 8 | 46 | 16 |
| 10Q GAIN WILD-TYPE | 96 | 192 | 76 |
Figure S127. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00859 (Fisher's exact test), Q value = 0.023
Table S128. Gene #21: '11p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 15 | 10 | 7 |
| 11P GAIN MUTATED | 2 | 0 | 4 |
| 11P GAIN WILD-TYPE | 13 | 10 | 3 |
Figure S128. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0107 (Fisher's exact test), Q value = 0.028
Table S129. Gene #21: '11p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 11P GAIN MUTATED | 2 | 0 | 4 |
| 11P GAIN WILD-TYPE | 12 | 11 | 3 |
Figure S129. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00241 (Fisher's exact test), Q value = 0.0083
Table S130. Gene #21: '11p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 11P GAIN MUTATED | 40 | 26 | 11 | 17 |
| 11P GAIN WILD-TYPE | 132 | 112 | 121 | 57 |
Figure S130. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S131. Gene #21: '11p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 11P GAIN MUTATED | 18 | 18 | 29 | 0 | 15 | 7 | 7 |
| 11P GAIN WILD-TYPE | 60 | 92 | 68 | 48 | 38 | 42 | 70 |
Figure S131. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00034
Table S132. Gene #21: '11p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 11P GAIN MUTATED | 16 | 48 | 29 |
| 11P GAIN WILD-TYPE | 170 | 173 | 74 |
Figure S132. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S133. Gene #21: '11p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 11P GAIN MUTATED | 4 | 11 | 25 | 13 | 31 | 9 |
| 11P GAIN WILD-TYPE | 67 | 28 | 120 | 117 | 65 | 20 |
Figure S133. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00274 (Fisher's exact test), Q value = 0.0093
Table S134. Gene #21: '11p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 11P GAIN MUTATED | 8 | 49 | 22 |
| 11P GAIN WILD-TYPE | 96 | 189 | 70 |
Figure S134. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0178 (Fisher's exact test), Q value = 0.043
Table S135. Gene #22: '11q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 15 | 10 | 7 |
| 11Q GAIN MUTATED | 3 | 1 | 5 |
| 11Q GAIN WILD-TYPE | 12 | 9 | 2 |
Figure S135. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0169 (Fisher's exact test), Q value = 0.041
Table S136. Gene #22: '11q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 11Q GAIN MUTATED | 3 | 1 | 5 |
| 11Q GAIN WILD-TYPE | 11 | 10 | 2 |
Figure S136. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S137. Gene #22: '11q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 11Q GAIN MUTATED | 59 | 31 | 11 | 17 |
| 11Q GAIN WILD-TYPE | 113 | 107 | 121 | 57 |
Figure S137. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0308 (Fisher's exact test), Q value = 0.067
Table S138. Gene #22: '11q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 11Q GAIN MUTATED | 38 | 20 | 15 | 34 | 11 |
| 11Q GAIN WILD-TYPE | 92 | 99 | 75 | 81 | 47 |
Figure S138. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 3e-04
Table S139. Gene #22: '11q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 11Q GAIN MUTATED | 19 | 31 | 28 | 0 | 18 | 10 | 12 |
| 11Q GAIN WILD-TYPE | 59 | 79 | 69 | 48 | 35 | 39 | 65 |
Figure S139. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00017 (Fisher's exact test), Q value = 0.00083
Table S140. Gene #22: '11q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 11Q GAIN MUTATED | 24 | 59 | 32 |
| 11Q GAIN WILD-TYPE | 162 | 162 | 71 |
Figure S140. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00034
Table S141. Gene #22: '11q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 11Q GAIN MUTATED | 5 | 11 | 36 | 20 | 33 | 10 |
| 11Q GAIN WILD-TYPE | 66 | 28 | 109 | 110 | 63 | 19 |
Figure S141. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00306 (Fisher's exact test), Q value = 0.01
Table S142. Gene #22: '11q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 11Q GAIN MUTATED | 12 | 61 | 27 |
| 11Q GAIN WILD-TYPE | 92 | 177 | 65 |
Figure S142. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0275 (Fisher's exact test), Q value = 0.061
Table S143. Gene #23: '12p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 15 | 10 | 7 |
| 12P GAIN MUTATED | 1 | 3 | 4 |
| 12P GAIN WILD-TYPE | 14 | 7 | 3 |
Figure S143. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0463 (Fisher's exact test), Q value = 0.093
Table S144. Gene #23: '12p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 12P GAIN MUTATED | 1 | 3 | 4 |
| 12P GAIN WILD-TYPE | 13 | 8 | 3 |
Figure S144. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S145. Gene #23: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 12P GAIN MUTATED | 26 | 80 | 13 | 19 |
| 12P GAIN WILD-TYPE | 146 | 58 | 119 | 55 |
Figure S145. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 3e-04
Table S146. Gene #23: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 12P GAIN MUTATED | 59 | 44 | 19 |
| 12P GAIN WILD-TYPE | 97 | 126 | 110 |
Figure S146. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S147. Gene #23: '12p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 12P GAIN MUTATED | 36 | 7 | 39 | 44 | 12 |
| 12P GAIN WILD-TYPE | 94 | 112 | 51 | 71 | 46 |
Figure S147. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S148. Gene #23: '12p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 12P GAIN MUTATED | 8 | 30 | 31 | 4 | 27 | 25 | 13 |
| 12P GAIN WILD-TYPE | 70 | 80 | 66 | 44 | 26 | 24 | 64 |
Figure S148. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S149. Gene #23: '12p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 12P GAIN MUTATED | 27 | 82 | 27 |
| 12P GAIN WILD-TYPE | 159 | 139 | 76 |
Figure S149. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S150. Gene #23: '12p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 12P GAIN MUTATED | 10 | 16 | 40 | 18 | 45 | 7 |
| 12P GAIN WILD-TYPE | 61 | 23 | 105 | 112 | 51 | 22 |
Figure S150. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00253 (Fisher's exact test), Q value = 0.0087
Table S151. Gene #23: '12p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 12P GAIN MUTATED | 6 | 35 | 28 | 11 | 14 | 23 |
| 12P GAIN WILD-TYPE | 53 | 55 | 67 | 32 | 56 | 54 |
Figure S151. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S152. Gene #23: '12p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 12P GAIN MUTATED | 13 | 84 | 20 |
| 12P GAIN WILD-TYPE | 91 | 154 | 72 |
Figure S152. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S153. Gene #24: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 12Q GAIN MUTATED | 21 | 78 | 13 | 21 |
| 12Q GAIN WILD-TYPE | 151 | 60 | 119 | 53 |
Figure S153. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00034
Table S154. Gene #24: '12q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 12Q GAIN MUTATED | 56 | 44 | 17 |
| 12Q GAIN WILD-TYPE | 100 | 126 | 112 |
Figure S154. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0331 (Fisher's exact test), Q value = 0.071
Table S155. Gene #24: '12q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 12Q GAIN MUTATED | 20 | 3 | 20 | 30 | 25 |
| 12Q GAIN WILD-TYPE | 71 | 19 | 46 | 45 | 84 |
Figure S155. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S156. Gene #24: '12q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 12Q GAIN MUTATED | 30 | 6 | 37 | 51 | 9 |
| 12Q GAIN WILD-TYPE | 100 | 113 | 53 | 64 | 49 |
Figure S156. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S157. Gene #24: '12q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 12Q GAIN MUTATED | 8 | 30 | 25 | 4 | 32 | 26 | 8 |
| 12Q GAIN WILD-TYPE | 70 | 80 | 72 | 44 | 21 | 23 | 69 |
Figure S157. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S158. Gene #24: '12q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 12Q GAIN MUTATED | 26 | 82 | 23 |
| 12Q GAIN WILD-TYPE | 160 | 139 | 80 |
Figure S158. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S159. Gene #24: '12q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 12Q GAIN MUTATED | 13 | 19 | 35 | 13 | 42 | 9 |
| 12Q GAIN WILD-TYPE | 58 | 20 | 110 | 117 | 54 | 20 |
Figure S159. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00012 (Fisher's exact test), Q value = 0.00062
Table S160. Gene #24: '12q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 12Q GAIN MUTATED | 3 | 35 | 28 | 12 | 15 | 19 |
| 12Q GAIN WILD-TYPE | 56 | 55 | 67 | 31 | 55 | 58 |
Figure S160. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S161. Gene #24: '12q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 12Q GAIN MUTATED | 12 | 81 | 19 |
| 12Q GAIN WILD-TYPE | 92 | 157 | 73 |
Figure S161. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0143 (Fisher's exact test), Q value = 0.036
Table S162. Gene #25: '13q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 13Q GAIN MUTATED | 17 | 14 | 3 |
| 13Q GAIN WILD-TYPE | 139 | 156 | 126 |
Figure S162. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0227 (Fisher's exact test), Q value = 0.052
Table S163. Gene #25: '13q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 13Q GAIN MUTATED | 8 | 4 | 9 | 8 | 3 | 8 | 3 |
| 13Q GAIN WILD-TYPE | 70 | 106 | 88 | 40 | 50 | 41 | 74 |
Figure S163. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S164. Gene #26: '14q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 14Q GAIN MUTATED | 51 | 35 | 13 | 30 |
| 14Q GAIN WILD-TYPE | 121 | 103 | 119 | 44 |
Figure S164. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0292 (Fisher's exact test), Q value = 0.064
Table S165. Gene #26: '14q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 14Q GAIN MUTATED | 51 | 40 | 25 |
| 14Q GAIN WILD-TYPE | 105 | 130 | 104 |
Figure S165. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00047 (Fisher's exact test), Q value = 0.002
Table S166. Gene #26: '14q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 14Q GAIN MUTATED | 40 | 21 | 13 | 42 | 12 |
| 14Q GAIN WILD-TYPE | 90 | 98 | 77 | 73 | 46 |
Figure S166. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S167. Gene #26: '14q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 14Q GAIN MUTATED | 15 | 27 | 42 | 7 | 21 | 7 | 9 |
| 14Q GAIN WILD-TYPE | 63 | 83 | 55 | 41 | 32 | 42 | 68 |
Figure S167. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00043 (Fisher's exact test), Q value = 0.0018
Table S168. Gene #26: '14q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 14Q GAIN MUTATED | 29 | 60 | 36 |
| 14Q GAIN WILD-TYPE | 157 | 161 | 67 |
Figure S168. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00015 (Fisher's exact test), Q value = 0.00075
Table S169. Gene #26: '14q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 14Q GAIN MUTATED | 12 | 13 | 38 | 17 | 32 | 13 |
| 14Q GAIN WILD-TYPE | 59 | 26 | 107 | 113 | 64 | 16 |
Figure S169. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00626 (Fisher's exact test), Q value = 0.018
Table S170. Gene #26: '14q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 14Q GAIN MUTATED | 6 | 33 | 23 | 14 | 14 | 19 |
| 14Q GAIN WILD-TYPE | 53 | 57 | 72 | 29 | 56 | 58 |
Figure S170. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0248 (Fisher's exact test), Q value = 0.056
Table S171. Gene #26: '14q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 14Q GAIN MUTATED | 16 | 69 | 24 |
| 14Q GAIN WILD-TYPE | 88 | 169 | 68 |
Figure S171. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00151 (Fisher's exact test), Q value = 0.0055
Table S172. Gene #27: '15q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 15Q GAIN MUTATED | 8 | 21 | 7 | 2 |
| 15Q GAIN WILD-TYPE | 164 | 117 | 125 | 72 |
Figure S172. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0146 (Fisher's exact test), Q value = 0.037
Table S173. Gene #27: '15q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 15Q GAIN MUTATED | 18 | 6 | 7 |
| 15Q GAIN WILD-TYPE | 138 | 164 | 122 |
Figure S173. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S174. Gene #27: '15q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 15Q GAIN MUTATED | 3 | 6 | 20 | 7 | 2 |
| 15Q GAIN WILD-TYPE | 127 | 113 | 70 | 108 | 56 |
Figure S174. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S175. Gene #27: '15q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 15Q GAIN MUTATED | 2 | 1 | 4 | 3 | 4 | 16 | 8 |
| 15Q GAIN WILD-TYPE | 76 | 109 | 93 | 45 | 49 | 33 | 69 |
Figure S175. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00023 (Fisher's exact test), Q value = 0.0011
Table S176. Gene #28: '16p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 16P GAIN MUTATED | 66 | 33 | 25 | 13 |
| 16P GAIN WILD-TYPE | 106 | 105 | 107 | 61 |
Figure S176. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00342 (Fisher's exact test), Q value = 0.011
Table S177. Gene #28: '16p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 16P GAIN MUTATED | 36 | 7 | 20 | 16 | 18 |
| 16P GAIN WILD-TYPE | 55 | 15 | 46 | 59 | 91 |
Figure S177. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0206 (Fisher's exact test), Q value = 0.049
Table S178. Gene #28: '16p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 16P GAIN MUTATED | 39 | 39 | 15 | 24 | 20 |
| 16P GAIN WILD-TYPE | 91 | 80 | 75 | 91 | 38 |
Figure S178. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00702 (Fisher's exact test), Q value = 0.02
Table S179. Gene #28: '16p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 16P GAIN MUTATED | 33 | 26 | 33 | 9 | 9 | 10 | 17 |
| 16P GAIN WILD-TYPE | 45 | 84 | 64 | 39 | 44 | 39 | 60 |
Figure S179. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0302 (Fisher's exact test), Q value = 0.066
Table S180. Gene #28: '16p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 16P GAIN MUTATED | 42 | 56 | 38 |
| 16P GAIN WILD-TYPE | 144 | 165 | 65 |
Figure S180. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00556 (Fisher's exact test), Q value = 0.017
Table S181. Gene #28: '16p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 16P GAIN MUTATED | 17 | 13 | 34 | 29 | 26 | 17 |
| 16P GAIN WILD-TYPE | 54 | 26 | 111 | 101 | 70 | 12 |
Figure S181. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0165 (Fisher's exact test), Q value = 0.041
Table S182. Gene #29: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 16Q GAIN MUTATED | 46 | 27 | 17 | 11 |
| 16Q GAIN WILD-TYPE | 126 | 111 | 115 | 63 |
Figure S182. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0152 (Fisher's exact test), Q value = 0.038
Table S183. Gene #29: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 16Q GAIN MUTATED | 26 | 45 | 29 |
| 16Q GAIN WILD-TYPE | 160 | 176 | 74 |
Figure S183. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0146 (Fisher's exact test), Q value = 0.037
Table S184. Gene #29: '16q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 16Q GAIN MUTATED | 8 | 8 | 28 | 22 | 21 | 13 |
| 16Q GAIN WILD-TYPE | 63 | 31 | 117 | 108 | 75 | 16 |
Figure S184. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00268 (Fisher's exact test), Q value = 0.0091
Table S185. Gene #30: '17p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 17P GAIN MUTATED | 30 | 30 | 9 | 15 |
| 17P GAIN WILD-TYPE | 142 | 108 | 123 | 59 |
Figure S185. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0159 (Fisher's exact test), Q value = 0.04
Table S186. Gene #30: '17p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 17P GAIN MUTATED | 30 | 25 | 3 |
| 17P GAIN WILD-TYPE | 137 | 108 | 60 |
Figure S186. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0407 (Fisher's exact test), Q value = 0.084
Table S187. Gene #30: '17p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 17P GAIN MUTATED | 24 | 11 | 12 | 27 | 10 |
| 17P GAIN WILD-TYPE | 106 | 108 | 78 | 88 | 48 |
Figure S187. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0225 (Fisher's exact test), Q value = 0.052
Table S188. Gene #30: '17p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 17P GAIN MUTATED | 12 | 14 | 22 | 4 | 16 | 8 | 8 |
| 17P GAIN WILD-TYPE | 66 | 96 | 75 | 44 | 37 | 41 | 69 |
Figure S188. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00948 (Fisher's exact test), Q value = 0.025
Table S189. Gene #30: '17p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 17P GAIN MUTATED | 19 | 47 | 16 |
| 17P GAIN WILD-TYPE | 167 | 174 | 87 |
Figure S189. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00015 (Fisher's exact test), Q value = 0.00075
Table S190. Gene #30: '17p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 17P GAIN MUTATED | 4 | 16 | 23 | 15 | 20 | 4 |
| 17P GAIN WILD-TYPE | 67 | 23 | 122 | 115 | 76 | 25 |
Figure S190. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S191. Gene #31: '17q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 17Q GAIN MUTATED | 88 | 61 | 16 | 26 |
| 17Q GAIN WILD-TYPE | 84 | 77 | 116 | 48 |
Figure S191. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00073 (Fisher's exact test), Q value = 0.0029
Table S192. Gene #31: '17q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 17Q GAIN MUTATED | 57 | 77 | 31 |
| 17Q GAIN WILD-TYPE | 99 | 93 | 98 |
Figure S192. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00024
Table S193. Gene #31: '17q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 17Q GAIN MUTATED | 68 | 27 | 29 | 46 | 20 |
| 17Q GAIN WILD-TYPE | 62 | 92 | 61 | 69 | 38 |
Figure S193. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S194. Gene #31: '17q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 17Q GAIN MUTATED | 29 | 53 | 45 | 5 | 27 | 12 | 19 |
| 17Q GAIN WILD-TYPE | 49 | 57 | 52 | 43 | 26 | 37 | 58 |
Figure S194. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00094 (Fisher's exact test), Q value = 0.0036
Table S195. Gene #31: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 17Q GAIN MUTATED | 50 | 98 | 41 |
| 17Q GAIN WILD-TYPE | 136 | 123 | 62 |
Figure S195. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00039
Table S196. Gene #31: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 17Q GAIN MUTATED | 18 | 23 | 59 | 32 | 47 | 10 |
| 17Q GAIN WILD-TYPE | 53 | 16 | 86 | 98 | 49 | 19 |
Figure S196. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00286 (Fisher's exact test), Q value = 0.0096
Table S197. Gene #31: '17q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 17Q GAIN MUTATED | 9 | 39 | 42 | 16 | 24 | 33 |
| 17Q GAIN WILD-TYPE | 50 | 51 | 53 | 27 | 46 | 44 |
Figure S197. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00013 (Fisher's exact test), Q value = 0.00067
Table S198. Gene #31: '17q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 17Q GAIN MUTATED | 21 | 103 | 39 |
| 17Q GAIN WILD-TYPE | 83 | 135 | 53 |
Figure S198. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S199. Gene #32: '18p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 18P GAIN MUTATED | 36 | 25 | 7 | 24 |
| 18P GAIN WILD-TYPE | 136 | 113 | 125 | 50 |
Figure S199. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S200. Gene #32: '18p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 18P GAIN MUTATED | 41 | 34 | 7 |
| 18P GAIN WILD-TYPE | 115 | 136 | 122 |
Figure S200. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0137 (Fisher's exact test), Q value = 0.035
Table S201. Gene #32: '18p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 18P GAIN MUTATED | 25 | 14 | 11 | 32 | 9 |
| 18P GAIN WILD-TYPE | 105 | 105 | 79 | 83 | 49 |
Figure S201. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00106 (Fisher's exact test), Q value = 0.004
Table S202. Gene #32: '18p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 18P GAIN MUTATED | 10 | 15 | 26 | 4 | 19 | 6 | 11 |
| 18P GAIN WILD-TYPE | 68 | 95 | 71 | 44 | 34 | 43 | 66 |
Figure S202. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00229 (Fisher's exact test), Q value = 0.008
Table S203. Gene #32: '18p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 18P GAIN MUTATED | 20 | 53 | 18 |
| 18P GAIN WILD-TYPE | 166 | 168 | 85 |
Figure S203. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0356 (Fisher's exact test), Q value = 0.075
Table S204. Gene #32: '18p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 18P GAIN MUTATED | 6 | 9 | 29 | 18 | 25 | 4 |
| 18P GAIN WILD-TYPE | 65 | 30 | 116 | 112 | 71 | 25 |
Figure S204. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00482 (Fisher's exact test), Q value = 0.015
Table S205. Gene #32: '18p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 18P GAIN MUTATED | 5 | 28 | 14 | 8 | 8 | 17 |
| 18P GAIN WILD-TYPE | 54 | 62 | 81 | 35 | 62 | 60 |
Figure S205. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00024
Table S206. Gene #32: '18p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 18P GAIN MUTATED | 6 | 59 | 15 |
| 18P GAIN WILD-TYPE | 98 | 179 | 77 |
Figure S206. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S207. Gene #33: '18q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 18Q GAIN MUTATED | 21 | 22 | 5 | 21 |
| 18Q GAIN WILD-TYPE | 151 | 116 | 127 | 53 |
Figure S207. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S208. Gene #33: '18q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 18Q GAIN MUTATED | 37 | 21 | 3 |
| 18Q GAIN WILD-TYPE | 119 | 149 | 126 |
Figure S208. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00024
Table S209. Gene #33: '18q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 18Q GAIN MUTATED | 12 | 11 | 8 | 33 | 4 |
| 18Q GAIN WILD-TYPE | 118 | 108 | 82 | 82 | 54 |
Figure S209. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00024
Table S210. Gene #33: '18q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 18Q GAIN MUTATED | 5 | 8 | 19 | 6 | 19 | 5 | 6 |
| 18Q GAIN WILD-TYPE | 73 | 102 | 78 | 42 | 34 | 44 | 71 |
Figure S210. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00702 (Fisher's exact test), Q value = 0.02
Table S211. Gene #33: '18q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 18Q GAIN MUTATED | 15 | 41 | 12 |
| 18Q GAIN WILD-TYPE | 171 | 180 | 91 |
Figure S211. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00166 (Fisher's exact test), Q value = 0.0059
Table S212. Gene #33: '18q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 18Q GAIN MUTATED | 5 | 10 | 17 | 11 | 23 | 2 |
| 18Q GAIN WILD-TYPE | 66 | 29 | 128 | 119 | 73 | 27 |
Figure S212. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S213. Gene #33: '18q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 18Q GAIN MUTATED | 4 | 30 | 8 | 5 | 4 | 8 |
| 18Q GAIN WILD-TYPE | 55 | 60 | 87 | 38 | 66 | 69 |
Figure S213. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00052 (Fisher's exact test), Q value = 0.0021
Table S214. Gene #33: '18q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 18Q GAIN MUTATED | 5 | 45 | 9 |
| 18Q GAIN WILD-TYPE | 99 | 193 | 83 |
Figure S214. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00082 (Fisher's exact test), Q value = 0.0032
Table S215. Gene #35: '19q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 19Q GAIN MUTATED | 22 | 29 | 9 | 18 |
| 19Q GAIN WILD-TYPE | 150 | 109 | 123 | 56 |
Figure S215. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00737 (Fisher's exact test), Q value = 0.02
Table S216. Gene #35: '19q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 19Q GAIN MUTATED | 37 | 20 | 16 |
| 19Q GAIN WILD-TYPE | 119 | 150 | 113 |
Figure S216. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0418 (Fisher's exact test), Q value = 0.086
Table S217. Gene #35: '19q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 19Q GAIN MUTATED | 10 | 2 | 10 | 21 | 15 |
| 19Q GAIN WILD-TYPE | 81 | 20 | 56 | 54 | 94 |
Figure S217. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.039 (Fisher's exact test), Q value = 0.081
Table S218. Gene #35: '19q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 19Q GAIN MUTATED | 5 | 13 | 16 | 11 | 10 | 12 | 9 |
| 19Q GAIN WILD-TYPE | 73 | 97 | 81 | 37 | 43 | 37 | 68 |
Figure S218. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0279 (Fisher's exact test), Q value = 0.062
Table S219. Gene #35: '19q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 19Q GAIN MUTATED | 17 | 46 | 7 |
| 19Q GAIN WILD-TYPE | 87 | 192 | 85 |
Figure S219. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S220. Gene #36: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 20P GAIN MUTATED | 63 | 59 | 15 | 38 |
| 20P GAIN WILD-TYPE | 109 | 79 | 117 | 36 |
Figure S220. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S221. Gene #36: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 20P GAIN MUTATED | 75 | 48 | 30 |
| 20P GAIN WILD-TYPE | 81 | 122 | 99 |
Figure S221. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00181 (Fisher's exact test), Q value = 0.0064
Table S222. Gene #36: '20p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 20P GAIN MUTATED | 43 | 60 | 19 |
| 20P GAIN WILD-TYPE | 124 | 73 | 44 |
Figure S222. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S223. Gene #36: '20p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 20P GAIN MUTATED | 42 | 27 | 31 | 59 | 12 |
| 20P GAIN WILD-TYPE | 88 | 92 | 59 | 56 | 46 |
Figure S223. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S224. Gene #36: '20p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 20P GAIN MUTATED | 12 | 33 | 54 | 14 | 27 | 16 | 15 |
| 20P GAIN WILD-TYPE | 66 | 77 | 43 | 34 | 26 | 33 | 62 |
Figure S224. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 2e-04
Table S225. Gene #36: '20p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 20P GAIN MUTATED | 39 | 92 | 41 |
| 20P GAIN WILD-TYPE | 147 | 129 | 62 |
Figure S225. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00019 (Fisher's exact test), Q value = 0.00091
Table S226. Gene #36: '20p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 20P GAIN MUTATED | 15 | 14 | 56 | 29 | 47 | 11 |
| 20P GAIN WILD-TYPE | 56 | 25 | 89 | 101 | 49 | 18 |
Figure S226. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00776 (Fisher's exact test), Q value = 0.021
Table S227. Gene #36: '20p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 20P GAIN MUTATED | 14 | 42 | 24 | 20 | 21 | 25 |
| 20P GAIN WILD-TYPE | 45 | 48 | 71 | 23 | 49 | 52 |
Figure S227. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00039
Table S228. Gene #36: '20p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 20P GAIN MUTATED | 22 | 101 | 23 |
| 20P GAIN WILD-TYPE | 82 | 137 | 69 |
Figure S228. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0222 (Fisher's exact test), Q value = 0.052
Table S229. Gene #37: '20q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 15 | 10 | 7 |
| 20Q GAIN MUTATED | 2 | 2 | 5 |
| 20Q GAIN WILD-TYPE | 13 | 8 | 2 |
Figure S229. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0239 (Fisher's exact test), Q value = 0.054
Table S230. Gene #37: '20q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 20Q GAIN MUTATED | 2 | 2 | 5 |
| 20Q GAIN WILD-TYPE | 12 | 9 | 2 |
Figure S230. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S231. Gene #37: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 20Q GAIN MUTATED | 76 | 71 | 14 | 40 |
| 20Q GAIN WILD-TYPE | 96 | 67 | 118 | 34 |
Figure S231. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S232. Gene #37: '20q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 20Q GAIN MUTATED | 84 | 60 | 32 |
| 20Q GAIN WILD-TYPE | 72 | 110 | 97 |
Figure S232. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0203 (Fisher's exact test), Q value = 0.048
Table S233. Gene #37: '20q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 20Q GAIN MUTATED | 33 | 8 | 18 | 41 | 44 |
| 20Q GAIN WILD-TYPE | 58 | 14 | 48 | 34 | 65 |
Figure S233. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S234. Gene #37: '20q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 20Q GAIN MUTATED | 47 | 73 | 24 |
| 20Q GAIN WILD-TYPE | 120 | 60 | 39 |
Figure S234. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S235. Gene #37: '20q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 20Q GAIN MUTATED | 53 | 26 | 36 | 65 | 17 |
| 20Q GAIN WILD-TYPE | 77 | 93 | 54 | 50 | 41 |
Figure S235. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S236. Gene #37: '20q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 20Q GAIN MUTATED | 12 | 46 | 61 | 14 | 29 | 18 | 17 |
| 20Q GAIN WILD-TYPE | 66 | 64 | 36 | 34 | 24 | 31 | 60 |
Figure S236. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S237. Gene #37: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 20Q GAIN MUTATED | 47 | 106 | 43 |
| 20Q GAIN WILD-TYPE | 139 | 115 | 60 |
Figure S237. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S238. Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 20Q GAIN MUTATED | 15 | 15 | 71 | 35 | 50 | 10 |
| 20Q GAIN WILD-TYPE | 56 | 24 | 74 | 95 | 46 | 19 |
Figure S238. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00191 (Fisher's exact test), Q value = 0.0067
Table S239. Gene #37: '20q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 20Q GAIN MUTATED | 13 | 48 | 32 | 21 | 23 | 31 |
| 20Q GAIN WILD-TYPE | 46 | 42 | 63 | 22 | 47 | 46 |
Figure S239. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S240. Gene #37: '20q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 20Q GAIN MUTATED | 20 | 118 | 30 |
| 20Q GAIN WILD-TYPE | 84 | 120 | 62 |
Figure S240. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S241. Gene #38: '21q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 21Q GAIN MUTATED | 62 | 13 | 15 | 8 |
| 21Q GAIN WILD-TYPE | 110 | 125 | 117 | 66 |
Figure S241. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.033 (Fisher's exact test), Q value = 0.071
Table S242. Gene #38: '21q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 21Q GAIN MUTATED | 29 | 3 | 12 | 11 | 17 |
| 21Q GAIN WILD-TYPE | 62 | 19 | 54 | 64 | 92 |
Figure S242. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00456 (Fisher's exact test), Q value = 0.014
Table S243. Gene #38: '21q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 21Q GAIN MUTATED | 35 | 30 | 11 | 15 | 7 |
| 21Q GAIN WILD-TYPE | 95 | 89 | 79 | 100 | 51 |
Figure S243. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00026 (Fisher's exact test), Q value = 0.0012
Table S244. Gene #38: '21q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 21Q GAIN MUTATED | 24 | 25 | 26 | 3 | 4 | 7 | 9 |
| 21Q GAIN WILD-TYPE | 54 | 85 | 71 | 45 | 49 | 42 | 68 |
Figure S244. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0426 (Fisher's exact test), Q value = 0.087
Table S245. Gene #39: '22q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 22Q GAIN MUTATED | 7 | 12 | 19 | 2 | 4 | 10 | 7 |
| 22Q GAIN WILD-TYPE | 71 | 98 | 78 | 46 | 49 | 39 | 70 |
Figure S245. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00635 (Fisher's exact test), Q value = 0.018
Table S246. Gene #40: 'xp gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| XP GAIN MUTATED | 25 | 16 | 6 |
| XP GAIN WILD-TYPE | 131 | 154 | 123 |
Figure S246. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0446 (Fisher's exact test), Q value = 0.09
Table S247. Gene #40: 'xp gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| XP GAIN MUTATED | 3 | 16 | 9 | 7 | 3 | 7 |
| XP GAIN WILD-TYPE | 56 | 74 | 86 | 36 | 67 | 70 |
Figure S247. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00059 (Fisher's exact test), Q value = 0.0024
Table S248. Gene #41: 'xq gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| XQ GAIN MUTATED | 43 | 16 | 12 | 15 |
| XQ GAIN WILD-TYPE | 129 | 122 | 120 | 59 |
Figure S248. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0485 (Fisher's exact test), Q value = 0.096
Table S249. Gene #41: 'xq gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| XQ GAIN MUTATED | 31 | 19 | 10 | 21 | 5 |
| XQ GAIN WILD-TYPE | 99 | 100 | 80 | 94 | 53 |
Figure S249. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0169 (Fisher's exact test), Q value = 0.041
Table S250. Gene #41: 'xq gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| XQ GAIN MUTATED | 12 | 23 | 27 | 5 | 6 | 4 | 9 |
| XQ GAIN WILD-TYPE | 66 | 87 | 70 | 43 | 47 | 45 | 68 |
Figure S250. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0131 (Fisher's exact test), Q value = 0.034
Table S251. Gene #42: '1p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 15 | 10 | 7 |
| 1P LOSS MUTATED | 0 | 4 | 1 |
| 1P LOSS WILD-TYPE | 15 | 6 | 6 |
Figure S251. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.038 (Fisher's exact test), Q value = 0.08
Table S252. Gene #42: '1p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 1P LOSS MUTATED | 0 | 4 | 1 |
| 1P LOSS WILD-TYPE | 14 | 7 | 6 |
Figure S252. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S253. Gene #42: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 1P LOSS MUTATED | 9 | 35 | 10 | 26 |
| 1P LOSS WILD-TYPE | 163 | 103 | 122 | 48 |
Figure S253. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00047 (Fisher's exact test), Q value = 0.002
Table S254. Gene #42: '1p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 1P LOSS MUTATED | 33 | 27 | 7 |
| 1P LOSS WILD-TYPE | 123 | 143 | 122 |
Figure S254. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0385 (Fisher's exact test), Q value = 0.081
Table S255. Gene #42: '1p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 1P LOSS MUTATED | 7 | 2 | 16 | 15 | 18 |
| 1P LOSS WILD-TYPE | 84 | 20 | 50 | 60 | 91 |
Figure S255. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00024
Table S256. Gene #42: '1p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 1P LOSS MUTATED | 14 | 10 | 20 | 31 | 3 |
| 1P LOSS WILD-TYPE | 116 | 109 | 70 | 84 | 55 |
Figure S256. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00024
Table S257. Gene #42: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 1P LOSS MUTATED | 7 | 17 | 10 | 10 | 19 | 12 | 3 |
| 1P LOSS WILD-TYPE | 71 | 93 | 87 | 38 | 34 | 37 | 74 |
Figure S257. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00722 (Fisher's exact test), Q value = 0.02
Table S258. Gene #42: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 1P LOSS MUTATED | 9 | 15 | 23 | 14 | 13 | 4 |
| 1P LOSS WILD-TYPE | 62 | 24 | 122 | 116 | 83 | 25 |
Figure S258. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00577 (Fisher's exact test), Q value = 0.017
Table S259. Gene #42: '1p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 1P LOSS MUTATED | 3 | 23 | 14 | 8 | 9 | 6 |
| 1P LOSS WILD-TYPE | 56 | 67 | 81 | 35 | 61 | 71 |
Figure S259. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00569 (Fisher's exact test), Q value = 0.017
Table S260. Gene #43: '1q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 1Q LOSS MUTATED | 3 | 10 | 6 | 9 |
| 1Q LOSS WILD-TYPE | 169 | 128 | 126 | 65 |
Figure S260. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00409 (Fisher's exact test), Q value = 0.013
Table S261. Gene #43: '1q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 1Q LOSS MUTATED | 14 | 10 | 1 |
| 1Q LOSS WILD-TYPE | 142 | 160 | 128 |
Figure S261. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0178 (Fisher's exact test), Q value = 0.043
Table S262. Gene #43: '1q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 1Q LOSS MUTATED | 6 | 3 | 9 | 10 | 0 |
| 1Q LOSS WILD-TYPE | 124 | 116 | 81 | 105 | 58 |
Figure S262. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0357 (Fisher's exact test), Q value = 0.075
Table S263. Gene #43: '1q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 1Q LOSS MUTATED | 1 | 9 | 7 | 2 | 0 | 6 |
| 1Q LOSS WILD-TYPE | 58 | 81 | 88 | 41 | 70 | 71 |
Figure S263. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.039 (Fisher's exact test), Q value = 0.081
Table S264. Gene #44: '2p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 2P LOSS MUTATED | 7 | 7 | 10 |
| 2P LOSS WILD-TYPE | 179 | 214 | 93 |
Figure S264. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S265. Gene #46: '3p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 3P LOSS MUTATED | 84 | 68 | 21 | 38 |
| 3P LOSS WILD-TYPE | 88 | 70 | 111 | 36 |
Figure S265. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00019 (Fisher's exact test), Q value = 0.00091
Table S266. Gene #46: '3p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 3P LOSS MUTATED | 82 | 65 | 37 |
| 3P LOSS WILD-TYPE | 74 | 105 | 92 |
Figure S266. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S267. Gene #46: '3p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 3P LOSS MUTATED | 29 | 38 | 49 | 17 | 34 | 24 | 17 |
| 3P LOSS WILD-TYPE | 49 | 72 | 48 | 31 | 19 | 25 | 60 |
Figure S267. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00813 (Fisher's exact test), Q value = 0.022
Table S268. Gene #46: '3p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 3P LOSS MUTATED | 59 | 100 | 48 |
| 3P LOSS WILD-TYPE | 127 | 121 | 55 |
Figure S268. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00029 (Fisher's exact test), Q value = 0.0013
Table S269. Gene #46: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 3P LOSS MUTATED | 29 | 25 | 51 | 41 | 52 | 9 |
| 3P LOSS WILD-TYPE | 42 | 14 | 94 | 89 | 44 | 20 |
Figure S269. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0112 (Fisher's exact test), Q value = 0.03
Table S270. Gene #46: '3p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 3P LOSS MUTATED | 21 | 52 | 38 | 18 | 25 | 24 |
| 3P LOSS WILD-TYPE | 38 | 38 | 57 | 25 | 45 | 53 |
Figure S270. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0343 (Fisher's exact test), Q value = 0.073
Table S271. Gene #46: '3p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 3P LOSS MUTATED | 32 | 109 | 37 |
| 3P LOSS WILD-TYPE | 72 | 129 | 55 |
Figure S271. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S272. Gene #47: '3q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 3Q LOSS MUTATED | 58 | 37 | 18 | 31 |
| 3Q LOSS WILD-TYPE | 114 | 101 | 114 | 43 |
Figure S272. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0394 (Fisher's exact test), Q value = 0.082
Table S273. Gene #47: '3q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 3Q LOSS MUTATED | 50 | 51 | 25 |
| 3Q LOSS WILD-TYPE | 106 | 119 | 104 |
Figure S273. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00538 (Fisher's exact test), Q value = 0.016
Table S274. Gene #47: '3q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 3Q LOSS MUTATED | 24 | 29 | 20 | 17 | 24 | 15 | 12 |
| 3Q LOSS WILD-TYPE | 54 | 81 | 77 | 31 | 29 | 34 | 65 |
Figure S274. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0225 (Fisher's exact test), Q value = 0.052
Table S275. Gene #47: '3q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 3Q LOSS MUTATED | 25 | 19 | 37 | 30 | 25 | 5 |
| 3Q LOSS WILD-TYPE | 46 | 20 | 108 | 100 | 71 | 24 |
Figure S275. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S276. Gene #48: '4p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 4P LOSS MUTATED | 39 | 46 | 8 | 26 |
| 4P LOSS WILD-TYPE | 133 | 92 | 124 | 48 |
Figure S276. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0027 (Fisher's exact test), Q value = 0.0092
Table S277. Gene #48: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 4P LOSS MUTATED | 49 | 30 | 21 |
| 4P LOSS WILD-TYPE | 107 | 140 | 108 |
Figure S277. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00117 (Fisher's exact test), Q value = 0.0044
Table S278. Gene #48: '4p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 4P LOSS MUTATED | 20 | 7 | 10 | 32 | 21 |
| 4P LOSS WILD-TYPE | 71 | 15 | 56 | 43 | 88 |
Figure S278. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00464 (Fisher's exact test), Q value = 0.014
Table S279. Gene #48: '4p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 4P LOSS MUTATED | 40 | 43 | 7 |
| 4P LOSS WILD-TYPE | 127 | 90 | 56 |
Figure S279. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00048 (Fisher's exact test), Q value = 0.002
Table S280. Gene #48: '4p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 4P LOSS MUTATED | 29 | 13 | 22 | 40 | 14 |
| 4P LOSS WILD-TYPE | 101 | 106 | 68 | 75 | 44 |
Figure S280. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S281. Gene #48: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 4P LOSS MUTATED | 13 | 17 | 39 | 2 | 21 | 14 | 12 |
| 4P LOSS WILD-TYPE | 65 | 93 | 58 | 46 | 32 | 35 | 65 |
Figure S281. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S282. Gene #48: '4p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 4P LOSS MUTATED | 22 | 75 | 21 |
| 4P LOSS WILD-TYPE | 164 | 146 | 82 |
Figure S282. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S283. Gene #48: '4p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 4P LOSS MUTATED | 6 | 16 | 39 | 19 | 36 | 2 |
| 4P LOSS WILD-TYPE | 65 | 23 | 106 | 111 | 60 | 27 |
Figure S283. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00866 (Fisher's exact test), Q value = 0.023
Table S284. Gene #48: '4p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 4P LOSS MUTATED | 5 | 31 | 22 | 8 | 18 | 15 |
| 4P LOSS WILD-TYPE | 54 | 59 | 73 | 35 | 52 | 62 |
Figure S284. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00339 (Fisher's exact test), Q value = 0.011
Table S285. Gene #48: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 4P LOSS MUTATED | 16 | 69 | 14 |
| 4P LOSS WILD-TYPE | 88 | 169 | 78 |
Figure S285. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00519 (Fisher's exact test), Q value = 0.016
Table S286. Gene #49: '4q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 15 | 10 | 7 |
| 4Q LOSS MUTATED | 1 | 2 | 5 |
| 4Q LOSS WILD-TYPE | 14 | 8 | 2 |
Figure S286. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00706 (Fisher's exact test), Q value = 0.02
Table S287. Gene #49: '4q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 4Q LOSS MUTATED | 1 | 2 | 5 |
| 4Q LOSS WILD-TYPE | 13 | 9 | 2 |
Figure S287. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S288. Gene #49: '4q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 4Q LOSS MUTATED | 41 | 57 | 7 | 31 |
| 4Q LOSS WILD-TYPE | 131 | 81 | 125 | 43 |
Figure S288. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S289. Gene #49: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 4Q LOSS MUTATED | 62 | 31 | 22 |
| 4Q LOSS WILD-TYPE | 94 | 139 | 107 |
Figure S289. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0267 (Fisher's exact test), Q value = 0.06
Table S290. Gene #49: '4q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 4Q LOSS MUTATED | 25 | 6 | 12 | 32 | 28 |
| 4Q LOSS WILD-TYPE | 66 | 16 | 54 | 43 | 81 |
Figure S290. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0184 (Fisher's exact test), Q value = 0.044
Table S291. Gene #49: '4q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 4Q LOSS MUTATED | 44 | 48 | 11 |
| 4Q LOSS WILD-TYPE | 123 | 85 | 52 |
Figure S291. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S292. Gene #49: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 4Q LOSS MUTATED | 34 | 11 | 27 | 50 | 13 |
| 4Q LOSS WILD-TYPE | 96 | 108 | 63 | 65 | 45 |
Figure S292. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S293. Gene #49: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 4Q LOSS MUTATED | 11 | 17 | 43 | 5 | 28 | 20 | 11 |
| 4Q LOSS WILD-TYPE | 67 | 93 | 54 | 43 | 25 | 29 | 66 |
Figure S293. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S294. Gene #49: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 4Q LOSS MUTATED | 24 | 82 | 29 |
| 4Q LOSS WILD-TYPE | 162 | 139 | 74 |
Figure S294. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S295. Gene #49: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 4Q LOSS MUTATED | 8 | 16 | 45 | 19 | 44 | 3 |
| 4Q LOSS WILD-TYPE | 63 | 23 | 100 | 111 | 52 | 26 |
Figure S295. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00015 (Fisher's exact test), Q value = 0.00075
Table S296. Gene #49: '4q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 4Q LOSS MUTATED | 5 | 38 | 23 | 11 | 20 | 16 |
| 4Q LOSS WILD-TYPE | 54 | 52 | 72 | 32 | 50 | 61 |
Figure S296. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 3e-04 (Fisher's exact test), Q value = 0.0013
Table S297. Gene #49: '4q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 4Q LOSS MUTATED | 16 | 80 | 17 |
| 4Q LOSS WILD-TYPE | 88 | 158 | 75 |
Figure S297. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00024
Table S298. Gene #50: '5p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 5P LOSS MUTATED | 9 | 23 | 3 | 10 |
| 5P LOSS WILD-TYPE | 163 | 115 | 129 | 64 |
Figure S298. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.018 (Fisher's exact test), Q value = 0.043
Table S299. Gene #50: '5p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 5P LOSS MUTATED | 20 | 11 | 5 |
| 5P LOSS WILD-TYPE | 136 | 159 | 124 |
Figure S299. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.009 (Fisher's exact test), Q value = 0.024
Table S300. Gene #50: '5p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 5P LOSS MUTATED | 6 | 1 | 3 | 15 | 6 |
| 5P LOSS WILD-TYPE | 85 | 21 | 63 | 60 | 103 |
Figure S300. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00023 (Fisher's exact test), Q value = 0.0011
Table S301. Gene #50: '5p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 5P LOSS MUTATED | 7 | 22 | 2 |
| 5P LOSS WILD-TYPE | 160 | 111 | 61 |
Figure S301. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00595 (Fisher's exact test), Q value = 0.017
Table S302. Gene #50: '5p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 5P LOSS MUTATED | 4 | 8 | 12 | 2 | 7 | 9 | 1 |
| 5P LOSS WILD-TYPE | 74 | 102 | 85 | 46 | 46 | 40 | 76 |
Figure S302. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0203 (Fisher's exact test), Q value = 0.048
Table S303. Gene #50: '5p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 5P LOSS MUTATED | 8 | 26 | 9 |
| 5P LOSS WILD-TYPE | 178 | 195 | 94 |
Figure S303. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0175 (Fisher's exact test), Q value = 0.042
Table S304. Gene #50: '5p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 5P LOSS MUTATED | 2 | 4 | 13 | 6 | 16 | 2 |
| 5P LOSS WILD-TYPE | 69 | 35 | 132 | 124 | 80 | 27 |
Figure S304. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0146 (Fisher's exact test), Q value = 0.037
Table S305. Gene #50: '5p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 5P LOSS MUTATED | 0 | 13 | 8 | 5 | 4 | 4 |
| 5P LOSS WILD-TYPE | 59 | 77 | 87 | 38 | 66 | 73 |
Figure S305. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00235 (Fisher's exact test), Q value = 0.0081
Table S306. Gene #50: '5p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 5P LOSS MUTATED | 1 | 26 | 7 |
| 5P LOSS WILD-TYPE | 103 | 212 | 85 |
Figure S306. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.03 (Fisher's exact test), Q value = 0.066
Table S307. Gene #51: '5q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 15 | 10 | 7 |
| 5Q LOSS MUTATED | 1 | 4 | 4 |
| 5Q LOSS WILD-TYPE | 14 | 6 | 3 |
Figure S307. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0351 (Fisher's exact test), Q value = 0.074
Table S308. Gene #51: '5q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 5Q LOSS MUTATED | 1 | 4 | 4 |
| 5Q LOSS WILD-TYPE | 13 | 7 | 3 |
Figure S308. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S309. Gene #51: '5q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 5Q LOSS MUTATED | 51 | 53 | 6 | 33 |
| 5Q LOSS WILD-TYPE | 121 | 85 | 126 | 41 |
Figure S309. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S310. Gene #51: '5q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 5Q LOSS MUTATED | 59 | 53 | 13 |
| 5Q LOSS WILD-TYPE | 97 | 117 | 116 |
Figure S310. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00024
Table S311. Gene #51: '5q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 5Q LOSS MUTATED | 30 | 6 | 12 | 36 | 18 |
| 5Q LOSS WILD-TYPE | 61 | 16 | 54 | 39 | 91 |
Figure S311. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00034
Table S312. Gene #51: '5q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 5Q LOSS MUTATED | 36 | 57 | 9 |
| 5Q LOSS WILD-TYPE | 131 | 76 | 54 |
Figure S312. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S313. Gene #51: '5q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 5Q LOSS MUTATED | 46 | 14 | 22 | 47 | 12 |
| 5Q LOSS WILD-TYPE | 84 | 105 | 68 | 68 | 46 |
Figure S313. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S314. Gene #51: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 5Q LOSS MUTATED | 6 | 37 | 34 | 9 | 21 | 18 | 16 |
| 5Q LOSS WILD-TYPE | 72 | 73 | 63 | 39 | 32 | 31 | 61 |
Figure S314. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S315. Gene #51: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 5Q LOSS MUTATED | 29 | 83 | 28 |
| 5Q LOSS WILD-TYPE | 157 | 138 | 75 |
Figure S315. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S316. Gene #51: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 5Q LOSS MUTATED | 8 | 13 | 50 | 20 | 45 | 4 |
| 5Q LOSS WILD-TYPE | 63 | 26 | 95 | 110 | 51 | 25 |
Figure S316. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S317. Gene #51: '5q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 5Q LOSS MUTATED | 4 | 41 | 30 | 9 | 13 | 24 |
| 5Q LOSS WILD-TYPE | 55 | 49 | 65 | 34 | 57 | 53 |
Figure S317. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S318. Gene #51: '5q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 5Q LOSS MUTATED | 11 | 88 | 22 |
| 5Q LOSS WILD-TYPE | 93 | 150 | 70 |
Figure S318. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00398 (Fisher's exact test), Q value = 0.013
Table S319. Gene #52: '6p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 6P LOSS MUTATED | 23 | 48 | 20 |
| 6P LOSS WILD-TYPE | 133 | 122 | 109 |
Figure S319. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S320. Gene #53: '6q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 6Q LOSS MUTATED | 59 | 98 | 37 |
| 6Q LOSS WILD-TYPE | 97 | 72 | 92 |
Figure S320. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00071
Table S321. Gene #53: '6q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 6Q LOSS MUTATED | 29 | 58 | 27 | 28 | 30 | 18 | 24 |
| 6Q LOSS WILD-TYPE | 49 | 52 | 70 | 20 | 23 | 31 | 53 |
Figure S321. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00081 (Fisher's exact test), Q value = 0.0031
Table S322. Gene #53: '6q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 6Q LOSS MUTATED | 31 | 18 | 77 | 43 | 29 | 17 |
| 6Q LOSS WILD-TYPE | 40 | 21 | 68 | 87 | 67 | 12 |
Figure S322. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0206 (Fisher's exact test), Q value = 0.049
Table S323. Gene #53: '6q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 6Q LOSS MUTATED | 37 | 96 | 50 |
| 6Q LOSS WILD-TYPE | 67 | 142 | 42 |
Figure S323. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 0.00067
Table S324. Gene #54: '7p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 7P LOSS MUTATED | 2 | 16 | 7 | 9 |
| 7P LOSS WILD-TYPE | 170 | 122 | 125 | 65 |
Figure S324. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0443 (Fisher's exact test), Q value = 0.09
Table S325. Gene #54: '7p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 7P LOSS MUTATED | 16 | 9 | 4 |
| 7P LOSS WILD-TYPE | 140 | 161 | 125 |
Figure S325. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00999 (Fisher's exact test), Q value = 0.027
Table S326. Gene #54: '7p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 7P LOSS MUTATED | 3 | 6 | 8 | 15 | 2 |
| 7P LOSS WILD-TYPE | 127 | 113 | 82 | 100 | 56 |
Figure S326. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 0.00053
Table S327. Gene #54: '7p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 7P LOSS MUTATED | 2 | 3 | 7 | 7 | 8 | 7 | 0 |
| 7P LOSS WILD-TYPE | 76 | 107 | 90 | 41 | 45 | 42 | 77 |
Figure S327. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0194 (Fisher's exact test), Q value = 0.046
Table S328. Gene #55: '7q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 7Q LOSS MUTATED | 9 | 19 | 6 | 7 |
| 7Q LOSS WILD-TYPE | 163 | 119 | 126 | 67 |
Figure S328. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S329. Gene #56: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 8P LOSS MUTATED | 96 | 61 | 23 | 20 |
| 8P LOSS WILD-TYPE | 76 | 77 | 109 | 54 |
Figure S329. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0299 (Fisher's exact test), Q value = 0.065
Table S330. Gene #56: '8p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 8P LOSS MUTATED | 59 | 77 | 39 |
| 8P LOSS WILD-TYPE | 97 | 93 | 90 |
Figure S330. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0371 (Fisher's exact test), Q value = 0.078
Table S331. Gene #56: '8p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 8P LOSS MUTATED | 41 | 11 | 21 | 35 | 32 |
| 8P LOSS WILD-TYPE | 50 | 11 | 45 | 40 | 77 |
Figure S331. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0333 (Fisher's exact test), Q value = 0.071
Table S332. Gene #56: '8p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 8P LOSS MUTATED | 56 | 63 | 21 |
| 8P LOSS WILD-TYPE | 111 | 70 | 42 |
Figure S332. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S333. Gene #56: '8p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 8P LOSS MUTATED | 75 | 36 | 29 | 43 | 16 |
| 8P LOSS WILD-TYPE | 55 | 83 | 61 | 72 | 42 |
Figure S333. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00044
Table S334. Gene #56: '8p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 8P LOSS MUTATED | 33 | 54 | 51 | 8 | 15 | 15 | 23 |
| 8P LOSS WILD-TYPE | 45 | 56 | 46 | 40 | 38 | 34 | 54 |
Figure S334. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0311 (Fisher's exact test), Q value = 0.067
Table S335. Gene #56: '8p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 8P LOSS MUTATED | 59 | 98 | 41 |
| 8P LOSS WILD-TYPE | 127 | 123 | 62 |
Figure S335. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.023 (Fisher's exact test), Q value = 0.053
Table S336. Gene #56: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 8P LOSS MUTATED | 22 | 14 | 72 | 40 | 40 | 10 |
| 8P LOSS WILD-TYPE | 49 | 25 | 73 | 90 | 56 | 19 |
Figure S336. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00067 (Fisher's exact test), Q value = 0.0027
Table S337. Gene #56: '8p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 8P LOSS MUTATED | 12 | 33 | 40 | 10 | 35 | 38 |
| 8P LOSS WILD-TYPE | 47 | 57 | 55 | 33 | 35 | 39 |
Figure S337. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0318 (Fisher's exact test), Q value = 0.068
Table S338. Gene #56: '8p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 8P LOSS MUTATED | 29 | 100 | 39 |
| 8P LOSS WILD-TYPE | 75 | 138 | 53 |
Figure S338. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S339. Gene #57: '8q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 8Q LOSS MUTATED | 36 | 11 | 6 | 3 |
| 8Q LOSS WILD-TYPE | 136 | 127 | 126 | 71 |
Figure S339. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0412 (Fisher's exact test), Q value = 0.085
Table S340. Gene #57: '8q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 8Q LOSS MUTATED | 15 | 13 | 12 | 2 | 1 | 5 | 8 |
| 8Q LOSS WILD-TYPE | 63 | 97 | 85 | 46 | 52 | 44 | 69 |
Figure S340. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S341. Gene #58: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 9P LOSS MUTATED | 101 | 94 | 46 | 28 |
| 9P LOSS WILD-TYPE | 71 | 44 | 86 | 46 |
Figure S341. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00344 (Fisher's exact test), Q value = 0.011
Table S342. Gene #58: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 9P LOSS MUTATED | 96 | 85 | 54 |
| 9P LOSS WILD-TYPE | 60 | 85 | 75 |
Figure S342. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 3e-04
Table S343. Gene #58: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 9P LOSS MUTATED | 41 | 50 | 60 | 20 | 25 | 40 | 31 |
| 9P LOSS WILD-TYPE | 37 | 60 | 37 | 28 | 28 | 9 | 46 |
Figure S343. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0121 (Fisher's exact test), Q value = 0.031
Table S344. Gene #58: '9p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 9P LOSS MUTATED | 31 | 21 | 73 | 58 | 64 | 18 |
| 9P LOSS WILD-TYPE | 40 | 18 | 72 | 72 | 32 | 11 |
Figure S344. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0329 (Fisher's exact test), Q value = 0.071
Table S345. Gene #58: '9p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 9P LOSS MUTATED | 43 | 134 | 51 |
| 9P LOSS WILD-TYPE | 61 | 104 | 41 |
Figure S345. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S346. Gene #59: '9q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 9Q LOSS MUTATED | 94 | 90 | 32 | 33 |
| 9Q LOSS WILD-TYPE | 78 | 48 | 100 | 41 |
Figure S346. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0035 (Fisher's exact test), Q value = 0.011
Table S347. Gene #59: '9q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 9Q LOSS MUTATED | 89 | 74 | 49 |
| 9Q LOSS WILD-TYPE | 67 | 96 | 80 |
Figure S347. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00026 (Fisher's exact test), Q value = 0.0012
Table S348. Gene #59: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 9Q LOSS MUTATED | 39 | 46 | 58 | 14 | 30 | 32 | 28 |
| 9Q LOSS WILD-TYPE | 39 | 64 | 39 | 34 | 23 | 17 | 49 |
Figure S348. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00448 (Fisher's exact test), Q value = 0.014
Table S349. Gene #59: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 9Q LOSS MUTATED | 72 | 115 | 58 |
| 9Q LOSS WILD-TYPE | 114 | 106 | 45 |
Figure S349. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 2e-04
Table S350. Gene #59: '9q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 9Q LOSS MUTATED | 27 | 24 | 63 | 50 | 65 | 16 |
| 9Q LOSS WILD-TYPE | 44 | 15 | 82 | 80 | 31 | 13 |
Figure S350. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0127 (Fisher's exact test), Q value = 0.033
Table S351. Gene #59: '9q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 9Q LOSS MUTATED | 37 | 126 | 43 |
| 9Q LOSS WILD-TYPE | 67 | 112 | 49 |
Figure S351. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S352. Gene #60: '10p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 10P LOSS MUTATED | 66 | 24 | 12 | 8 |
| 10P LOSS WILD-TYPE | 106 | 114 | 120 | 66 |
Figure S352. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0483 (Fisher's exact test), Q value = 0.096
Table S353. Gene #60: '10p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 10P LOSS MUTATED | 28 | 6 | 12 | 17 | 15 |
| 10P LOSS WILD-TYPE | 63 | 16 | 54 | 58 | 94 |
Figure S353. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00112 (Fisher's exact test), Q value = 0.0042
Table S354. Gene #60: '10p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 10P LOSS MUTATED | 39 | 18 | 9 | 26 | 17 |
| 10P LOSS WILD-TYPE | 91 | 101 | 81 | 89 | 41 |
Figure S354. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S355. Gene #60: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 10P LOSS MUTATED | 17 | 27 | 38 | 0 | 10 | 4 | 13 |
| 10P LOSS WILD-TYPE | 61 | 83 | 59 | 48 | 43 | 45 | 64 |
Figure S355. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00757 (Fisher's exact test), Q value = 0.021
Table S356. Gene #60: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 10P LOSS MUTATED | 30 | 45 | 33 |
| 10P LOSS WILD-TYPE | 156 | 176 | 70 |
Figure S356. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 6e-04 (Fisher's exact test), Q value = 0.0024
Table S357. Gene #60: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 10P LOSS MUTATED | 9 | 11 | 24 | 24 | 25 | 15 |
| 10P LOSS WILD-TYPE | 62 | 28 | 121 | 106 | 71 | 14 |
Figure S357. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S358. Gene #61: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 10Q LOSS MUTATED | 71 | 36 | 12 | 13 |
| 10Q LOSS WILD-TYPE | 101 | 102 | 120 | 61 |
Figure S358. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.042 (Fisher's exact test), Q value = 0.086
Table S359. Gene #61: '10q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 10Q LOSS MUTATED | 48 | 42 | 23 |
| 10Q LOSS WILD-TYPE | 108 | 128 | 106 |
Figure S359. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00267 (Fisher's exact test), Q value = 0.0091
Table S360. Gene #61: '10q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 10Q LOSS MUTATED | 46 | 19 | 16 | 33 | 17 |
| 10Q LOSS WILD-TYPE | 84 | 100 | 74 | 82 | 41 |
Figure S360. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S361. Gene #61: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 10Q LOSS MUTATED | 20 | 31 | 49 | 0 | 10 | 9 | 12 |
| 10Q LOSS WILD-TYPE | 58 | 79 | 48 | 48 | 43 | 40 | 65 |
Figure S361. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00934 (Fisher's exact test), Q value = 0.025
Table S362. Gene #61: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 10Q LOSS MUTATED | 35 | 59 | 36 |
| 10Q LOSS WILD-TYPE | 151 | 162 | 67 |
Figure S362. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.00083
Table S363. Gene #61: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 10Q LOSS MUTATED | 9 | 9 | 34 | 27 | 36 | 15 |
| 10Q LOSS WILD-TYPE | 62 | 30 | 111 | 103 | 60 | 14 |
Figure S363. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0425 (Fisher's exact test), Q value = 0.087
Table S364. Gene #61: '10q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 10Q LOSS MUTATED | 7 | 29 | 20 | 14 | 19 | 23 |
| 10Q LOSS WILD-TYPE | 52 | 61 | 75 | 29 | 51 | 54 |
Figure S364. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.007 (Fisher's exact test), Q value = 0.02
Table S365. Gene #61: '10q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 10Q LOSS MUTATED | 16 | 74 | 22 |
| 10Q LOSS WILD-TYPE | 88 | 164 | 70 |
Figure S365. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0343 (Fisher's exact test), Q value = 0.073
Table S366. Gene #62: '11p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 15 | 10 | 7 |
| 11P LOSS MUTATED | 0 | 3 | 2 |
| 11P LOSS WILD-TYPE | 15 | 7 | 5 |
Figure S366. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S367. Gene #62: '11p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 11P LOSS MUTATED | 41 | 46 | 8 | 16 |
| 11P LOSS WILD-TYPE | 131 | 92 | 124 | 58 |
Figure S367. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00058
Table S368. Gene #62: '11p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 11P LOSS MUTATED | 48 | 36 | 13 |
| 11P LOSS WILD-TYPE | 108 | 134 | 116 |
Figure S368. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.023 (Fisher's exact test), Q value = 0.053
Table S369. Gene #62: '11p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 11P LOSS MUTATED | 27 | 39 | 13 |
| 11P LOSS WILD-TYPE | 140 | 94 | 50 |
Figure S369. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00064 (Fisher's exact test), Q value = 0.0026
Table S370. Gene #62: '11p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 11P LOSS MUTATED | 36 | 11 | 24 | 29 | 8 |
| 11P LOSS WILD-TYPE | 94 | 108 | 66 | 86 | 50 |
Figure S370. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.00079
Table S371. Gene #62: '11p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 11P LOSS MUTATED | 6 | 29 | 25 | 9 | 13 | 18 | 8 |
| 11P LOSS WILD-TYPE | 72 | 81 | 72 | 39 | 40 | 31 | 69 |
Figure S371. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0417 (Fisher's exact test), Q value = 0.086
Table S372. Gene #62: '11p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 11P LOSS MUTATED | 14 | 8 | 41 | 20 | 24 | 2 |
| 11P LOSS WILD-TYPE | 57 | 31 | 104 | 110 | 72 | 27 |
Figure S372. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 2e-04
Table S373. Gene #62: '11p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 11P LOSS MUTATED | 7 | 30 | 31 | 3 | 11 | 10 |
| 11P LOSS WILD-TYPE | 52 | 60 | 64 | 40 | 59 | 67 |
Figure S373. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S374. Gene #63: '11q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 11Q LOSS MUTATED | 27 | 36 | 6 | 18 |
| 11Q LOSS WILD-TYPE | 145 | 102 | 126 | 56 |
Figure S374. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 0.00053
Table S375. Gene #63: '11q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 11Q LOSS MUTATED | 41 | 26 | 10 |
| 11Q LOSS WILD-TYPE | 115 | 144 | 119 |
Figure S375. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00138 (Fisher's exact test), Q value = 0.005
Table S376. Gene #63: '11q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 11Q LOSS MUTATED | 25 | 7 | 18 | 27 | 7 |
| 11Q LOSS WILD-TYPE | 105 | 112 | 72 | 88 | 51 |
Figure S376. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00356 (Fisher's exact test), Q value = 0.012
Table S377. Gene #63: '11q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 11Q LOSS MUTATED | 5 | 20 | 18 | 8 | 15 | 12 | 6 |
| 11Q LOSS WILD-TYPE | 73 | 90 | 79 | 40 | 38 | 37 | 71 |
Figure S377. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00644 (Fisher's exact test), Q value = 0.018
Table S378. Gene #63: '11q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 11Q LOSS MUTATED | 6 | 23 | 21 | 2 | 10 | 8 |
| 11Q LOSS WILD-TYPE | 53 | 67 | 74 | 41 | 60 | 69 |
Figure S378. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S379. Gene #64: '12p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 12P LOSS MUTATED | 67 | 8 | 22 | 12 |
| 12P LOSS WILD-TYPE | 105 | 130 | 110 | 62 |
Figure S379. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00708 (Fisher's exact test), Q value = 0.02
Table S380. Gene #64: '12p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 12P LOSS MUTATED | 26 | 10 | 16 | 12 | 16 |
| 12P LOSS WILD-TYPE | 65 | 12 | 50 | 63 | 93 |
Figure S380. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00039 (Fisher's exact test), Q value = 0.0017
Table S381. Gene #64: '12p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 12P LOSS MUTATED | 37 | 33 | 8 | 16 | 14 |
| 12P LOSS WILD-TYPE | 93 | 86 | 82 | 99 | 44 |
Figure S381. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00058
Table S382. Gene #64: '12p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 12P LOSS MUTATED | 19 | 24 | 32 | 11 | 2 | 3 | 17 |
| 12P LOSS WILD-TYPE | 59 | 86 | 65 | 37 | 51 | 46 | 60 |
Figure S382. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S383. Gene #65: '12q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 12Q LOSS MUTATED | 63 | 4 | 18 | 9 |
| 12Q LOSS WILD-TYPE | 109 | 134 | 114 | 65 |
Figure S383. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00044
Table S384. Gene #65: '12q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 12Q LOSS MUTATED | 34 | 28 | 7 | 11 | 13 |
| 12Q LOSS WILD-TYPE | 96 | 91 | 83 | 104 | 45 |
Figure S384. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00013 (Fisher's exact test), Q value = 0.00067
Table S385. Gene #65: '12q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 12Q LOSS MUTATED | 16 | 21 | 27 | 10 | 1 | 2 | 16 |
| 12Q LOSS WILD-TYPE | 62 | 89 | 70 | 38 | 52 | 47 | 61 |
Figure S385. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0214 (Fisher's exact test), Q value = 0.05
Table S386. Gene #65: '12q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 12Q LOSS MUTATED | 14 | 1 | 32 | 29 | 12 | 5 |
| 12Q LOSS WILD-TYPE | 57 | 38 | 113 | 101 | 84 | 24 |
Figure S386. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S387. Gene #66: '13q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 13Q LOSS MUTATED | 105 | 85 | 24 | 37 |
| 13Q LOSS WILD-TYPE | 67 | 53 | 108 | 37 |
Figure S387. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00049
Table S388. Gene #66: '13q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 13Q LOSS MUTATED | 54 | 7 | 28 | 50 | 39 |
| 13Q LOSS WILD-TYPE | 37 | 15 | 38 | 25 | 70 |
Figure S388. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S389. Gene #66: '13q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 13Q LOSS MUTATED | 82 | 38 | 34 | 69 | 25 |
| 13Q LOSS WILD-TYPE | 48 | 81 | 56 | 46 | 33 |
Figure S389. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S390. Gene #66: '13q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 13Q LOSS MUTATED | 33 | 68 | 53 | 11 | 37 | 18 | 28 |
| 13Q LOSS WILD-TYPE | 45 | 42 | 44 | 37 | 16 | 31 | 49 |
Figure S390. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00321 (Fisher's exact test), Q value = 0.011
Table S391. Gene #66: '13q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 13Q LOSS MUTATED | 72 | 120 | 56 |
| 13Q LOSS WILD-TYPE | 114 | 101 | 47 |
Figure S391. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00164 (Fisher's exact test), Q value = 0.0059
Table S392. Gene #66: '13q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 13Q LOSS MUTATED | 31 | 27 | 80 | 47 | 51 | 12 |
| 13Q LOSS WILD-TYPE | 40 | 12 | 65 | 83 | 45 | 17 |
Figure S392. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0215 (Fisher's exact test), Q value = 0.05
Table S393. Gene #66: '13q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 13Q LOSS MUTATED | 40 | 130 | 45 |
| 13Q LOSS WILD-TYPE | 64 | 108 | 47 |
Figure S393. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 3e-04 (Fisher's exact test), Q value = 0.0013
Table S394. Gene #67: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 14Q LOSS MUTATED | 38 | 45 | 15 | 16 |
| 14Q LOSS WILD-TYPE | 134 | 93 | 117 | 58 |
Figure S394. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0253 (Fisher's exact test), Q value = 0.057
Table S395. Gene #67: '14q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 14Q LOSS MUTATED | 42 | 38 | 18 |
| 14Q LOSS WILD-TYPE | 114 | 132 | 111 |
Figure S395. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00222 (Fisher's exact test), Q value = 0.0078
Table S396. Gene #67: '14q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 14Q LOSS MUTATED | 23 | 2 | 16 | 26 | 13 |
| 14Q LOSS WILD-TYPE | 68 | 20 | 50 | 49 | 96 |
Figure S396. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00928 (Fisher's exact test), Q value = 0.025
Table S397. Gene #67: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 14Q LOSS MUTATED | 12 | 25 | 20 | 10 | 12 | 22 | 12 |
| 14Q LOSS WILD-TYPE | 66 | 85 | 77 | 38 | 41 | 27 | 65 |
Figure S397. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0155 (Fisher's exact test), Q value = 0.039
Table S398. Gene #67: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 14Q LOSS MUTATED | 33 | 63 | 18 |
| 14Q LOSS WILD-TYPE | 153 | 158 | 85 |
Figure S398. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0283 (Fisher's exact test), Q value = 0.062
Table S399. Gene #67: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 14Q LOSS MUTATED | 18 | 9 | 37 | 22 | 27 | 1 |
| 14Q LOSS WILD-TYPE | 53 | 30 | 108 | 108 | 69 | 28 |
Figure S399. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S400. Gene #68: '15q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 15Q LOSS MUTATED | 111 | 64 | 21 | 48 |
| 15Q LOSS WILD-TYPE | 61 | 74 | 111 | 26 |
Figure S400. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0015
Table S401. Gene #68: '15q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 15Q LOSS MUTATED | 75 | 95 | 42 |
| 15Q LOSS WILD-TYPE | 81 | 75 | 87 |
Figure S401. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S402. Gene #68: '15q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 15Q LOSS MUTATED | 90 | 35 | 20 | 66 | 29 |
| 15Q LOSS WILD-TYPE | 40 | 84 | 70 | 49 | 29 |
Figure S402. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S403. Gene #68: '15q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 15Q LOSS MUTATED | 34 | 68 | 56 | 8 | 36 | 9 | 29 |
| 15Q LOSS WILD-TYPE | 44 | 42 | 41 | 40 | 17 | 40 | 48 |
Figure S403. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00024
Table S404. Gene #68: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 15Q LOSS MUTATED | 63 | 121 | 57 |
| 15Q LOSS WILD-TYPE | 123 | 100 | 46 |
Figure S404. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00022 (Fisher's exact test), Q value = 0.001
Table S405. Gene #68: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 15Q LOSS MUTATED | 25 | 27 | 76 | 46 | 55 | 12 |
| 15Q LOSS WILD-TYPE | 46 | 12 | 69 | 84 | 41 | 17 |
Figure S405. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00419 (Fisher's exact test), Q value = 0.013
Table S406. Gene #68: '15q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 15Q LOSS MUTATED | 14 | 48 | 50 | 21 | 37 | 36 |
| 15Q LOSS WILD-TYPE | 45 | 42 | 45 | 22 | 33 | 41 |
Figure S406. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00029 (Fisher's exact test), Q value = 0.0013
Table S407. Gene #68: '15q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 15Q LOSS MUTATED | 32 | 125 | 49 |
| 15Q LOSS WILD-TYPE | 72 | 113 | 43 |
Figure S407. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S408. Gene #69: '16p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 16P LOSS MUTATED | 36 | 32 | 9 | 30 |
| 16P LOSS WILD-TYPE | 136 | 106 | 123 | 44 |
Figure S408. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00022 (Fisher's exact test), Q value = 0.001
Table S409. Gene #69: '16p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 16P LOSS MUTATED | 42 | 41 | 12 |
| 16P LOSS WILD-TYPE | 114 | 129 | 117 |
Figure S409. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00331 (Fisher's exact test), Q value = 0.011
Table S410. Gene #69: '16p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 16P LOSS MUTATED | 19 | 5 | 8 | 28 | 18 |
| 16P LOSS WILD-TYPE | 72 | 17 | 58 | 47 | 91 |
Figure S410. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00045 (Fisher's exact test), Q value = 0.0019
Table S411. Gene #69: '16p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 16P LOSS MUTATED | 28 | 43 | 7 |
| 16P LOSS WILD-TYPE | 139 | 90 | 56 |
Figure S411. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S412. Gene #69: '16p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 16P LOSS MUTATED | 39 | 8 | 21 | 32 | 7 |
| 16P LOSS WILD-TYPE | 91 | 111 | 69 | 83 | 51 |
Figure S412. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00071
Table S413. Gene #69: '16p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 16P LOSS MUTATED | 8 | 37 | 25 | 8 | 13 | 10 | 6 |
| 16P LOSS WILD-TYPE | 70 | 73 | 72 | 40 | 40 | 39 | 71 |
Figure S413. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00696 (Fisher's exact test), Q value = 0.02
Table S414. Gene #69: '16p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 16P LOSS MUTATED | 27 | 60 | 20 |
| 16P LOSS WILD-TYPE | 159 | 161 | 83 |
Figure S414. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00044 (Fisher's exact test), Q value = 0.0019
Table S415. Gene #69: '16p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 16P LOSS MUTATED | 10 | 5 | 43 | 18 | 29 | 2 |
| 16P LOSS WILD-TYPE | 61 | 34 | 102 | 112 | 67 | 27 |
Figure S415. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 0.00049
Table S416. Gene #69: '16p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 16P LOSS MUTATED | 3 | 33 | 23 | 6 | 10 | 18 |
| 16P LOSS WILD-TYPE | 56 | 57 | 72 | 37 | 60 | 59 |
Figure S416. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00205 (Fisher's exact test), Q value = 0.0072
Table S417. Gene #69: '16p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 16P LOSS MUTATED | 11 | 64 | 18 |
| 16P LOSS WILD-TYPE | 93 | 174 | 74 |
Figure S417. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S418. Gene #70: '16q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 16Q LOSS MUTATED | 51 | 41 | 13 | 32 |
| 16Q LOSS WILD-TYPE | 121 | 97 | 119 | 42 |
Figure S418. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 2e-04
Table S419. Gene #70: '16q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 16Q LOSS MUTATED | 49 | 54 | 15 |
| 16Q LOSS WILD-TYPE | 107 | 116 | 114 |
Figure S419. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00029 (Fisher's exact test), Q value = 0.0013
Table S420. Gene #70: '16q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 16Q LOSS MUTATED | 28 | 7 | 10 | 34 | 21 |
| 16Q LOSS WILD-TYPE | 63 | 15 | 56 | 41 | 88 |
Figure S420. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00478 (Fisher's exact test), Q value = 0.015
Table S421. Gene #70: '16q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 16Q LOSS MUTATED | 38 | 50 | 12 |
| 16Q LOSS WILD-TYPE | 129 | 83 | 51 |
Figure S421. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S422. Gene #70: '16q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 16Q LOSS MUTATED | 58 | 13 | 24 | 35 | 7 |
| 16Q LOSS WILD-TYPE | 72 | 106 | 66 | 80 | 51 |
Figure S422. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S423. Gene #70: '16q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 16Q LOSS MUTATED | 13 | 50 | 32 | 9 | 14 | 10 | 9 |
| 16Q LOSS WILD-TYPE | 65 | 60 | 65 | 39 | 39 | 39 | 68 |
Figure S423. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00602 (Fisher's exact test), Q value = 0.017
Table S424. Gene #70: '16q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 16Q LOSS MUTATED | 36 | 74 | 27 |
| 16Q LOSS WILD-TYPE | 150 | 147 | 76 |
Figure S424. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00113 (Fisher's exact test), Q value = 0.0042
Table S425. Gene #70: '16q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 16Q LOSS MUTATED | 17 | 8 | 52 | 22 | 34 | 4 |
| 16Q LOSS WILD-TYPE | 54 | 31 | 93 | 108 | 62 | 25 |
Figure S425. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00132 (Fisher's exact test), Q value = 0.0048
Table S426. Gene #70: '16q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 16Q LOSS MUTATED | 5 | 35 | 27 | 9 | 17 | 22 |
| 16Q LOSS WILD-TYPE | 54 | 55 | 68 | 34 | 53 | 55 |
Figure S426. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00497 (Fisher's exact test), Q value = 0.015
Table S427. Gene #70: '16q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 16Q LOSS MUTATED | 16 | 76 | 23 |
| 16Q LOSS WILD-TYPE | 88 | 162 | 69 |
Figure S427. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S428. Gene #71: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 17P LOSS MUTATED | 97 | 63 | 26 | 33 |
| 17P LOSS WILD-TYPE | 75 | 75 | 106 | 41 |
Figure S428. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00034
Table S429. Gene #71: '17p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 17P LOSS MUTATED | 63 | 92 | 37 |
| 17P LOSS WILD-TYPE | 93 | 78 | 92 |
Figure S429. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0184 (Fisher's exact test), Q value = 0.044
Table S430. Gene #71: '17p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 17P LOSS MUTATED | 48 | 11 | 20 | 38 | 40 |
| 17P LOSS WILD-TYPE | 43 | 11 | 46 | 37 | 69 |
Figure S430. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00076 (Fisher's exact test), Q value = 0.003
Table S431. Gene #71: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 17P LOSS MUTATED | 71 | 33 | 40 | 50 | 23 |
| 17P LOSS WILD-TYPE | 59 | 86 | 50 | 65 | 35 |
Figure S431. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00034
Table S432. Gene #71: '17p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 17P LOSS MUTATED | 29 | 65 | 46 | 8 | 21 | 20 | 28 |
| 17P LOSS WILD-TYPE | 49 | 45 | 51 | 40 | 32 | 29 | 49 |
Figure S432. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.011 (Fisher's exact test), Q value = 0.029
Table S433. Gene #71: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 17P LOSS MUTATED | 26 | 10 | 78 | 49 | 43 | 11 |
| 17P LOSS WILD-TYPE | 45 | 29 | 67 | 81 | 53 | 18 |
Figure S433. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00034
Table S434. Gene #71: '17p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 17P LOSS MUTATED | 13 | 39 | 54 | 14 | 23 | 40 |
| 17P LOSS WILD-TYPE | 46 | 51 | 41 | 29 | 47 | 37 |
Figure S434. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0202 (Fisher's exact test), Q value = 0.048
Table S435. Gene #71: '17p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 17P LOSS MUTATED | 32 | 106 | 45 |
| 17P LOSS WILD-TYPE | 72 | 132 | 47 |
Figure S435. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00053 (Fisher's exact test), Q value = 0.0022
Table S436. Gene #72: '17q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 17Q LOSS MUTATED | 30 | 17 | 4 | 9 |
| 17Q LOSS WILD-TYPE | 142 | 121 | 128 | 65 |
Figure S436. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S437. Gene #73: '18p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 18P LOSS MUTATED | 77 | 57 | 28 | 18 |
| 18P LOSS WILD-TYPE | 95 | 81 | 104 | 56 |
Figure S437. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0451 (Fisher's exact test), Q value = 0.091
Table S438. Gene #73: '18p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 18P LOSS MUTATED | 34 | 8 | 22 | 38 | 31 |
| 18P LOSS WILD-TYPE | 57 | 14 | 44 | 37 | 78 |
Figure S438. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00618 (Fisher's exact test), Q value = 0.018
Table S439. Gene #73: '18p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 18P LOSS MUTATED | 50 | 63 | 20 |
| 18P LOSS WILD-TYPE | 117 | 70 | 43 |
Figure S439. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0016 (Fisher's exact test), Q value = 0.0057
Table S440. Gene #73: '18p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 18P LOSS MUTATED | 61 | 33 | 37 | 30 | 17 |
| 18P LOSS WILD-TYPE | 69 | 86 | 53 | 85 | 41 |
Figure S440. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.00079
Table S441. Gene #73: '18p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 18P LOSS MUTATED | 30 | 51 | 37 | 9 | 11 | 23 | 17 |
| 18P LOSS WILD-TYPE | 48 | 59 | 60 | 39 | 42 | 26 | 60 |
Figure S441. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00413 (Fisher's exact test), Q value = 0.013
Table S442. Gene #73: '18p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 18P LOSS MUTATED | 52 | 76 | 49 |
| 18P LOSS WILD-TYPE | 134 | 145 | 54 |
Figure S442. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S443. Gene #74: '18q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 18Q LOSS MUTATED | 97 | 64 | 38 | 16 |
| 18Q LOSS WILD-TYPE | 75 | 74 | 94 | 58 |
Figure S443. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0149 (Fisher's exact test), Q value = 0.037
Table S444. Gene #74: '18q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 18Q LOSS MUTATED | 47 | 10 | 25 | 39 | 34 |
| 18Q LOSS WILD-TYPE | 44 | 12 | 41 | 36 | 75 |
Figure S444. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S445. Gene #74: '18q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 18Q LOSS MUTATED | 78 | 40 | 41 | 31 | 23 |
| 18Q LOSS WILD-TYPE | 52 | 79 | 49 | 84 | 35 |
Figure S445. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 2e-04
Table S446. Gene #74: '18q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 18Q LOSS MUTATED | 38 | 59 | 45 | 8 | 12 | 23 | 28 |
| 18Q LOSS WILD-TYPE | 40 | 51 | 52 | 40 | 41 | 26 | 49 |
Figure S446. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00614 (Fisher's exact test), Q value = 0.018
Table S447. Gene #74: '18q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 18Q LOSS MUTATED | 65 | 91 | 56 |
| 18Q LOSS WILD-TYPE | 121 | 130 | 47 |
Figure S447. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0104 (Fisher's exact test), Q value = 0.028
Table S448. Gene #74: '18q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 18Q LOSS MUTATED | 21 | 28 | 54 | 17 | 32 | 29 |
| 18Q LOSS WILD-TYPE | 38 | 62 | 41 | 26 | 38 | 48 |
Figure S448. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0247 (Fisher's exact test), Q value = 0.056
Table S449. Gene #74: '18q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 18Q LOSS MUTATED | 36 | 96 | 49 |
| 18Q LOSS WILD-TYPE | 68 | 142 | 43 |
Figure S449. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S450. Gene #75: '19p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 19P LOSS MUTATED | 76 | 88 | 37 | 44 |
| 19P LOSS WILD-TYPE | 96 | 50 | 95 | 30 |
Figure S450. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S451. Gene #75: '19p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 19P LOSS MUTATED | 105 | 77 | 30 |
| 19P LOSS WILD-TYPE | 51 | 93 | 99 |
Figure S451. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00152 (Fisher's exact test), Q value = 0.0055
Table S452. Gene #75: '19p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 19P LOSS MUTATED | 38 | 13 | 40 | 47 | 41 |
| 19P LOSS WILD-TYPE | 53 | 9 | 26 | 28 | 68 |
Figure S452. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S453. Gene #75: '19p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 19P LOSS MUTATED | 61 | 39 | 47 | 77 | 19 |
| 19P LOSS WILD-TYPE | 69 | 80 | 43 | 38 | 39 |
Figure S453. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S454. Gene #75: '19p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 19P LOSS MUTATED | 21 | 46 | 57 | 32 | 35 | 34 | 18 |
| 19P LOSS WILD-TYPE | 57 | 64 | 40 | 16 | 18 | 15 | 59 |
Figure S454. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S455. Gene #75: '19p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 19P LOSS MUTATED | 66 | 130 | 43 |
| 19P LOSS WILD-TYPE | 120 | 91 | 60 |
Figure S455. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00024
Table S456. Gene #75: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 19P LOSS MUTATED | 28 | 21 | 73 | 43 | 63 | 11 |
| 19P LOSS WILD-TYPE | 43 | 18 | 72 | 87 | 33 | 18 |
Figure S456. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 2e-04
Table S457. Gene #75: '19p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 19P LOSS MUTATED | 18 | 62 | 42 | 17 | 34 | 30 |
| 19P LOSS WILD-TYPE | 41 | 28 | 53 | 26 | 36 | 47 |
Figure S457. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00142 (Fisher's exact test), Q value = 0.0052
Table S458. Gene #75: '19p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 19P LOSS MUTATED | 39 | 130 | 34 |
| 19P LOSS WILD-TYPE | 65 | 108 | 58 |
Figure S458. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00014 (Fisher's exact test), Q value = 0.00071
Table S459. Gene #76: '19q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 19Q LOSS MUTATED | 61 | 53 | 21 | 24 |
| 19Q LOSS WILD-TYPE | 111 | 85 | 111 | 50 |
Figure S459. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S460. Gene #76: '19q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 19Q LOSS MUTATED | 64 | 56 | 17 |
| 19Q LOSS WILD-TYPE | 92 | 114 | 112 |
Figure S460. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0318 (Fisher's exact test), Q value = 0.068
Table S461. Gene #76: '19q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 19Q LOSS MUTATED | 25 | 8 | 28 | 31 | 26 |
| 19Q LOSS WILD-TYPE | 66 | 14 | 38 | 44 | 83 |
Figure S461. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00073 (Fisher's exact test), Q value = 0.0029
Table S462. Gene #76: '19q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 19Q LOSS MUTATED | 55 | 54 | 9 |
| 19Q LOSS WILD-TYPE | 112 | 79 | 54 |
Figure S462. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00227 (Fisher's exact test), Q value = 0.0079
Table S463. Gene #76: '19q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 19Q LOSS MUTATED | 45 | 24 | 29 | 48 | 12 |
| 19Q LOSS WILD-TYPE | 85 | 95 | 61 | 67 | 46 |
Figure S463. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00024
Table S464. Gene #76: '19q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 19Q LOSS MUTATED | 15 | 33 | 41 | 17 | 21 | 22 | 9 |
| 19Q LOSS WILD-TYPE | 63 | 77 | 56 | 31 | 32 | 27 | 68 |
Figure S464. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00099 (Fisher's exact test), Q value = 0.0038
Table S465. Gene #76: '19q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 19Q LOSS MUTATED | 39 | 84 | 31 |
| 19Q LOSS WILD-TYPE | 147 | 137 | 72 |
Figure S465. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00067 (Fisher's exact test), Q value = 0.0027
Table S466. Gene #76: '19q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 19Q LOSS MUTATED | 16 | 12 | 47 | 25 | 44 | 10 |
| 19Q LOSS WILD-TYPE | 55 | 27 | 98 | 105 | 52 | 19 |
Figure S466. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00331 (Fisher's exact test), Q value = 0.011
Table S467. Gene #76: '19q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 19Q LOSS MUTATED | 7 | 38 | 32 | 12 | 21 | 21 |
| 19Q LOSS WILD-TYPE | 52 | 52 | 63 | 31 | 49 | 56 |
Figure S467. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0113 (Fisher's exact test), Q value = 0.03
Table S468. Gene #76: '19q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 19Q LOSS MUTATED | 21 | 85 | 25 |
| 19Q LOSS WILD-TYPE | 83 | 153 | 67 |
Figure S468. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0232 (Fisher's exact test), Q value = 0.053
Table S469. Gene #77: '20p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 20P LOSS MUTATED | 49 | 32 | 22 | 10 |
| 20P LOSS WILD-TYPE | 123 | 106 | 110 | 64 |
Figure S469. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0113 (Fisher's exact test), Q value = 0.03
Table S470. Gene #77: '20p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 20P LOSS MUTATED | 24 | 49 | 25 |
| 20P LOSS WILD-TYPE | 132 | 121 | 104 |
Figure S470. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00698 (Fisher's exact test), Q value = 0.02
Table S471. Gene #77: '20p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 20P LOSS MUTATED | 30 | 1 | 16 | 16 | 16 |
| 20P LOSS WILD-TYPE | 61 | 21 | 50 | 59 | 93 |
Figure S471. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00464 (Fisher's exact test), Q value = 0.014
Table S472. Gene #77: '20p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 20P LOSS MUTATED | 39 | 23 | 24 | 13 | 14 |
| 20P LOSS WILD-TYPE | 91 | 96 | 66 | 102 | 44 |
Figure S472. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00078 (Fisher's exact test), Q value = 0.003
Table S473. Gene #77: '20p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 20P LOSS MUTATED | 23 | 37 | 13 | 5 | 7 | 14 | 14 |
| 20P LOSS WILD-TYPE | 55 | 73 | 84 | 43 | 46 | 35 | 63 |
Figure S473. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0139 (Fisher's exact test), Q value = 0.035
Table S474. Gene #77: '20p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 20P LOSS MUTATED | 7 | 17 | 32 | 5 | 13 | 17 |
| 20P LOSS WILD-TYPE | 52 | 73 | 63 | 38 | 57 | 60 |
Figure S474. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0234 (Fisher's exact test), Q value = 0.053
Table S475. Gene #77: '20p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 20P LOSS MUTATED | 15 | 48 | 28 |
| 20P LOSS WILD-TYPE | 89 | 190 | 64 |
Figure S475. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S476. Gene #79: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 21Q LOSS MUTATED | 33 | 74 | 19 | 40 |
| 21Q LOSS WILD-TYPE | 139 | 64 | 113 | 34 |
Figure S476. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00424 (Fisher's exact test), Q value = 0.013
Table S477. Gene #79: '21q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 21Q LOSS MUTATED | 59 | 54 | 26 |
| 21Q LOSS WILD-TYPE | 97 | 116 | 103 |
Figure S477. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00014
Table S478. Gene #79: '21q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 21Q LOSS MUTATED | 16 | 3 | 17 | 41 | 35 |
| 21Q LOSS WILD-TYPE | 75 | 19 | 49 | 34 | 74 |
Figure S478. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0068 (Fisher's exact test), Q value = 0.019
Table S479. Gene #79: '21q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 21Q LOSS MUTATED | 38 | 52 | 22 |
| 21Q LOSS WILD-TYPE | 129 | 81 | 41 |
Figure S479. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S480. Gene #79: '21q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 21Q LOSS MUTATED | 32 | 15 | 40 | 62 | 14 |
| 21Q LOSS WILD-TYPE | 98 | 104 | 50 | 53 | 44 |
Figure S480. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S481. Gene #79: '21q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 21Q LOSS MUTATED | 11 | 30 | 36 | 13 | 34 | 23 | 16 |
| 21Q LOSS WILD-TYPE | 67 | 80 | 61 | 35 | 19 | 26 | 61 |
Figure S481. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 2e-04
Table S482. Gene #79: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 21Q LOSS MUTATED | 39 | 91 | 32 |
| 21Q LOSS WILD-TYPE | 147 | 130 | 71 |
Figure S482. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00031 (Fisher's exact test), Q value = 0.0014
Table S483. Gene #79: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 21Q LOSS MUTATED | 15 | 15 | 49 | 30 | 47 | 6 |
| 21Q LOSS WILD-TYPE | 56 | 24 | 96 | 100 | 49 | 23 |
Figure S483. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-04 (Fisher's exact test), Q value = 0.00053
Table S484. Gene #79: '21q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 21Q LOSS MUTATED | 7 | 42 | 35 | 9 | 17 | 26 |
| 21Q LOSS WILD-TYPE | 52 | 48 | 60 | 34 | 53 | 51 |
Figure S484. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S485. Gene #79: '21q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 21Q LOSS MUTATED | 18 | 99 | 19 |
| 21Q LOSS WILD-TYPE | 86 | 139 | 73 |
Figure S485. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S486. Gene #80: '22q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| 22Q LOSS MUTATED | 78 | 71 | 24 | 48 |
| 22Q LOSS WILD-TYPE | 94 | 67 | 108 | 26 |
Figure S486. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S487. Gene #80: '22q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| 22Q LOSS MUTATED | 85 | 84 | 27 |
| 22Q LOSS WILD-TYPE | 71 | 86 | 102 |
Figure S487. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0165 (Fisher's exact test), Q value = 0.041
Table S488. Gene #80: '22q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| 22Q LOSS MUTATED | 41 | 5 | 23 | 43 | 44 |
| 22Q LOSS WILD-TYPE | 50 | 17 | 43 | 32 | 65 |
Figure S488. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0112 (Fisher's exact test), Q value = 0.03
Table S489. Gene #80: '22q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 167 | 133 | 63 |
| 22Q LOSS MUTATED | 59 | 70 | 27 |
| 22Q LOSS WILD-TYPE | 108 | 63 | 36 |
Figure S489. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S490. Gene #80: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 119 | 90 | 115 | 58 |
| 22Q LOSS MUTATED | 68 | 30 | 40 | 66 | 14 |
| 22Q LOSS WILD-TYPE | 62 | 89 | 50 | 49 | 44 |
Figure S490. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S491. Gene #80: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 22Q LOSS MUTATED | 24 | 59 | 46 | 15 | 34 | 23 | 17 |
| 22Q LOSS WILD-TYPE | 54 | 51 | 51 | 33 | 19 | 26 | 60 |
Figure S491. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00024
Table S492. Gene #80: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 186 | 221 | 103 |
| 22Q LOSS MUTATED | 58 | 117 | 41 |
| 22Q LOSS WILD-TYPE | 128 | 104 | 62 |
Figure S492. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.2e-05
Table S493. Gene #80: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 71 | 39 | 145 | 130 | 96 | 29 |
| 22Q LOSS MUTATED | 21 | 23 | 77 | 36 | 51 | 8 |
| 22Q LOSS WILD-TYPE | 50 | 16 | 68 | 94 | 45 | 21 |
Figure S493. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00582 (Fisher's exact test), Q value = 0.017
Table S494. Gene #80: '22q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 59 | 90 | 95 | 43 | 70 | 77 |
| 22Q LOSS MUTATED | 15 | 52 | 43 | 18 | 27 | 32 |
| 22Q LOSS WILD-TYPE | 44 | 38 | 52 | 25 | 43 | 45 |
Figure S494. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00048 (Fisher's exact test), Q value = 0.002
Table S495. Gene #80: '22q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 104 | 238 | 92 |
| 22Q LOSS MUTATED | 30 | 121 | 36 |
| 22Q LOSS WILD-TYPE | 74 | 117 | 56 |
Figure S495. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00904 (Fisher's exact test), Q value = 0.024
Table S496. Gene #81: 'xp loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 172 | 138 | 132 | 74 |
| XP LOSS MUTATED | 46 | 30 | 15 | 15 |
| XP LOSS WILD-TYPE | 126 | 108 | 117 | 59 |
Figure S496. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.043 (Fisher's exact test), Q value = 0.088
Table S497. Gene #81: 'xp loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| XP LOSS MUTATED | 33 | 42 | 17 |
| XP LOSS WILD-TYPE | 123 | 128 | 112 |
Figure S497. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00684 (Fisher's exact test), Q value = 0.019
Table S498. Gene #81: 'xp loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 22 | 66 | 75 | 109 |
| XP LOSS MUTATED | 26 | 2 | 5 | 18 | 19 |
| XP LOSS WILD-TYPE | 65 | 20 | 61 | 57 | 90 |
Figure S498. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00477 (Fisher's exact test), Q value = 0.015
Table S499. Gene #81: 'xp loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| XP LOSS MUTATED | 19 | 36 | 22 | 6 | 6 | 6 | 11 |
| XP LOSS WILD-TYPE | 59 | 74 | 75 | 42 | 47 | 43 | 66 |
Figure S499. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0056 (Fisher's exact test), Q value = 0.017
Table S500. Gene #82: 'xq loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 156 | 170 | 129 |
| XQ LOSS MUTATED | 23 | 26 | 6 |
| XQ LOSS WILD-TYPE | 133 | 144 | 123 |
Figure S500. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
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Copy number data file = broad_values_by_arm.txt from GISTIC pipeline
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Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/LUAD-TP/22531211/transformed.cor.cli.txt
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Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/LUAD-TP/22552673/LUAD-TP.transferedmergedcluster.txt
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Number of patients = 516
-
Number of significantly arm-level cnvs = 82
-
Number of molecular subtypes = 12
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Exclude genes that fewer than K tumors have mutations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.