		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
SPOP	57 (11%)	441	9.9999e-06	0.00055	9.9999e-06	0.00055	0.090599	0.48	0.88599	1	9.9999e-06	0.00055	9.9999e-06	0.00055	0.16267	0.582	0.16087	0.58	0.12159	0.51	0.33575	0.728
TP53	57 (11%)	441	9.9999e-06	0.00055	0.00436	0.103	0.00174	0.0547	0.056319	0.435	0.00234	0.0606	5e-05	0.00244	0.071059	0.447	0.0073099	0.128	0.01926	0.208	0.061129	0.447
PTEN	17 (3%)	481	0.53605	0.88	0.52311	0.879	0.35101	0.75	0.49471	0.86	0.01206	0.156	0.00113	0.041	0.54135	0.88	0.13001	0.523	0.67473	0.916	0.88231	1
NUDT11	11 (2%)	487	0.53384	0.88	0.90424	1	0.11935	0.51	0.088449	0.475	0.85096	1	0.92771	1	0.43629	0.813	0.51421	0.874	0.68526	0.924	0.51169	0.873
MLL2	29 (6%)	469	0.070119	0.447	0.096199	0.489	0.29653	0.712	0.48806	0.86	0.02629	0.257	0.0084799	0.138	0.30238	0.712	0.41887	0.805	0.0047	0.103	0.33505	0.728
CTNNB1	13 (3%)	485	0.18526	0.62	0.01016	0.142	0.10083	0.493	0.01206	0.156	0.065469	0.447	0.2066	0.658	0.065109	0.447	0.0075699	0.128	0.02088	0.209	0.11202	0.51
PIK3CA	14 (3%)	484	0.081059	0.466	0.01287	0.156	0.063659	0.447	0.58584	0.892	0.00466	0.103	0.0070399	0.128	0.0416	0.352	0.01031	0.142	0.54843	0.88	0.15679	0.57
KDM6A	13 (3%)	485	0.49989	0.863	0.0201	0.209	0.49439	0.86	0.70456	0.937	0.0099799	0.142	0.0087599	0.138	0.080399	0.466	0.26389	0.682	0.30322	0.712	0.43597	0.813
FOXA1	28 (6%)	470	0.00099999	0.041	9.9999e-06	0.00055	0.0061999	0.128	0.078539	0.466	9.9999e-06	0.00055	9.9999e-06	0.00055	0.097729	0.489	0.0066299	0.128	0.1906	0.631	0.23913	0.666
MLL3	29 (6%)	469	0.03942	0.34	0.30161	0.712	0.79598	1	0.0073199	0.128	0.75379	0.981	0.70983	0.941	0.23933	0.666	0.38294	0.787	0.31215	0.712	0.01809	0.204
GAGE2A	5 (1%)	493	0.52261	0.879	0.66277	0.915	NA	NA	NA	NA	0.68305	0.924	0.45765	0.833	0.85883	1	0.58859	0.893	0.12515	0.519	0.28033	0.705
TNRC18	9 (2%)	489	0.32657	0.726	0.26513	0.682	0.56877	0.881	0.30692	0.712	0.66523	0.915	0.57171	0.881	0.41688	0.805	0.21027	0.658	0.50941	0.872	0.94372	1
AGAP6	5 (1%)	493	1	1	0.65923	0.915	0.48122	0.86	0.2488	0.673	0.22147	0.658	0.45841	0.833	0.74011	0.969	0.30733	0.712	0.41368	0.805	1	1
IDH1	6 (1%)	492	0.88727	1	0.01261	0.156	0.41835	0.805	0.33799	0.729	0.072119	0.447	0.01001	0.142	0.2791	0.705	0.11057	0.51	0.72918	0.961	0.20645	0.658
GATA6	4 (1%)	494	0.91706	1	0.53735	0.88	NA	NA	NA	NA	0.6571	0.915	0.82697	1	1	1	0.68907	0.924	0.62315	0.909	0.8844	1
SMG7	8 (2%)	490	0.03223	0.295	0.074059	0.453	0.54859	0.88	0.73312	0.963	0.01315	0.156	0.00218	0.0599	0.29659	0.712	0.087099	0.473	1	1	0.22809	0.658
CNTNAP1	9 (2%)	489	0.2218	0.658	0.16974	0.59	0.82585	1	1	1	0.5176	0.876	0.70107	0.935	0.9263	1	0.068719	0.447	0.84072	1	0.62642	0.909
CDKN1B	6 (1%)	492	0.31044	0.712	0.11718	0.51	0.10322	0.499	0.01727	0.2	0.56191	0.88	0.095769	0.489	0.28051	0.705	0.11158	0.51	0.28431	0.711	0.84022	1
EOMES	5 (1%)	493	0.25096	0.673	0.42935	0.813	0.66994	0.916	0.11455	0.51	0.93316	1	0.13552	0.527	0.41065	0.805	0.80349	1	0.31206	0.712	0.49025	0.86
NBPF1	9 (2%)	489	0.96674	1	0.10919	0.51	0.85443	1	0.77317	0.995	0.43286	0.813	0.42522	0.81	0.5601	0.88	0.34036	0.731	0.61856	0.909	0.36656	0.77
LMOD2	6 (1%)	492	0.4724	0.852	0.94567	1	0.67141	0.916	0.23167	0.658	0.39516	0.794	0.33096	0.728	0.29579	0.712	0.65011	0.914	0.94608	1	0.9661	1
EHHADH	5 (1%)	493	0.64112	0.914	0.81693	1	0.15343	0.563	0.88961	1	0.64825	0.914	1	1	0.47038	0.852	0.48554	0.86	NA	NA	NA	NA
MED12	8 (2%)	490	1	1	0.55406	0.88	0.98405	1	0.8965	1	0.96367	1	0.22308	0.658	0.84709	1	0.88707	1	0.57427	0.881	0.79989	1
ZNF709	5 (1%)	493	0.92289	1	0.25407	0.673	0.11484	0.51	0.096989	0.489	0.64783	0.914	0.54299	0.88	0.11975	0.51	0.25341	0.673	0.32972	0.728	0.31748	0.713
TCEB3	4 (1%)	494	0.83808	1	0.49398	0.86	0.2926	0.712	0.55229	0.88	0.20555	0.658	0.03421	0.301	0.90243	1	0.17416	0.599	0.38642	0.791	0.27951	0.705
MED15	7 (1%)	491	0.084429	0.468	0.14856	0.554	0.39677	0.794	0.57719	0.882	0.83736	1	0.22979	0.658	0.7876	1	0.65348	0.915	0.81258	1	0.80648	1
ERF	5 (1%)	493	1	1	0.22149	0.658	0.57332	0.881	0.060119	0.447	0.4054	0.803	0.63032	0.909	0.79786	1	0.12744	0.523	0.62911	0.909	0.69898	0.935
ERN1	4 (1%)	494	0.36728	0.77	0.01939	0.208	NA	NA	NA	NA	0.2297	0.658	0.55863	0.88	0.30202	0.712	0.79871	1	0.064199	0.447	0.13201	0.523
MLLT10	5 (1%)	493	0.16493	0.585	0.45032	0.833	0.76591	0.992	0.66024	0.915	1	1	0.62681	0.909	0.68643	0.924	0.59071	0.893	NA	NA	NA	NA
ZFHX3	16 (3%)	482	0.39711	0.794	0.17031	0.59	0.081539	0.466	0.77186	0.995	0.19493	0.64	0.10636	0.509	0.02053	0.209	0.31583	0.713	0.38136	0.787	0.9613	1
ZMYM3	12 (2%)	486	0.33549	0.728	0.00121	0.041	0.45222	0.833	0.051269	0.403	0.084349	0.468	0.14578	0.548	0.04548	0.371	0.63319	0.91	0.24581	0.673	0.2538	0.673
FMN1	4 (1%)	494	0.53936	0.88	0.19766	0.644	0.5689	0.881	0.61999	0.909	0.2275	0.658	1	1	0.82079	1	0.18562	0.62	NA	NA	NA	NA
AKT1	3 (1%)	495	1	1	0.03389	0.301	NA	NA	NA	NA	0.36724	0.77	0.1802	0.615	0.6492	0.914	1	1	NA	NA	NA	NA
ATM	22 (4%)	476	0.071239	0.447	0.25748	0.674	0.82842	1	0.82669	1	0.29292	0.712	0.02929	0.274	0.29576	0.712	0.22944	0.658	0.66315	0.915	0.47945	0.86
STRC	5 (1%)	493	0.64026	0.914	0.0484	0.387	NA	NA	NA	NA	0.54667	0.88	0.24765	0.673	0.13743	0.527	0.068669	0.447	NA	NA	NA	NA
APC	10 (2%)	488	0.43512	0.813	0.23013	0.658	0.37316	0.778	1	1	0.071159	0.447	0.14241	0.54	0.3195	0.714	0.31769	0.713	0.52642	0.88	0.36011	0.765
ZFP36L2	4 (1%)	494	0.54204	0.88	0.37957	0.787	0.091999	0.482	0.88999	1	0.23033	0.658	0.55748	0.88	1	1	0.21577	0.658	0.50036	0.863	0.59549	0.896
MYOT	5 (1%)	493	0.40989	0.805	0.02907	0.274	0.60569	0.897	0.11917	0.51	0.060229	0.447	0.30055	0.712	0.13523	0.527	0.12849	0.523	0.67256	0.916	0.42348	0.81
KIRREL	6 (1%)	492	0.099709	0.493	0.39463	0.794	0.86588	1	0.085159	0.468	0.56178	0.88	0.50889	0.872	0.59744	0.896	0.60557	0.897	0.72874	0.961	0.88254	1
PGBD2	3 (1%)	495	0.25731	0.674	0.18599	0.62	NA	NA	NA	NA	0.12084	0.51	0.25091	0.673	0.74358	0.971	0.2153	0.658	0.62779	0.909	0.59896	0.896
LOC100132247	3 (1%)	495	0.30874	0.712	1	1	NA	NA	NA	NA	1	1	1	1	1	1	0.90424	1	NA	NA	NA	NA
EMG1	4 (1%)	494	0.49472	0.86	0.115	0.51	NA	NA	NA	NA	0.40519	0.803	0.22219	0.658	0.0443	0.368	0.0011	0.041	NA	NA	NA	NA
CDH16	4 (1%)	494	0.45176	0.833	0.41749	0.805	0.76622	0.992	0.13174	0.523	0.13773	0.527	0.45427	0.833	0.23402	0.66	0.22107	0.658	0.38941	0.793	0.5536	0.88
KRT25	6 (1%)	492	0.60356	0.897	0.080349	0.466	0.84138	1	0.57438	0.881	0.15222	0.563	0.87475	1	0.26155	0.681	0.00194	0.0569	0.64928	0.914	0.16696	0.588
