Clinical Features Time to Death YEARS_TO_BIRTH PATHOLOGIC_STAGE PATHOLOGY_T_STAGE PATHOLOGY_N_STAGE GENDER RADIATION_THERAPY HISTOLOGICAL_TYPE RESIDUAL_TUMOR NUMBER_OF_LYMPH_NODES ETHNICITY nMutated (%) nWild-Type logrank test_P logrank test_Q Wilcoxon-test_P Wilcoxon-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Wilcoxon-test_P Wilcoxon-test_Q Fisher's exact test_P Fisher's exact test_Q ZFPM1 24 (39%) 38 0.30135 1 0.53413 1 0.31997 1 0.97426 1 0.66624 1 1 1 0.75867 1 1 1 0.14347 1 0.33009 1 0.67692 1 LACTB 19 (31%) 43 0.92281 1 0.94519 1 0.19392 1 0.10767 1 1 1 0.56782 1 1 1 0.18669 1 1 1 0.90056 1 0.65598 1 CCDC102A 17 (27%) 45 0.10396 1 0.47745 1 0.14524 1 0.20469 1 0.17026 1 1 1 0.73693 1 0.16615 1 0.78235 1 0.31034 1 1 1 ZNF517 13 (21%) 49 0.96764 1 0.042075 1 0.73656 1 0.75363 1 1 1 0.75624 1 0.12822 1 0.6213 1 0.42094 1 0.70482 1 0.30578 1 MAL2 11 (18%) 51 0.7272 1 0.070821 1 0.45011 1 0.04463 1 0.3017 1 0.078935 1 0.70745 1 1 1 0.80011 1 0.2352 1 0.29969 1 TOR3A 12 (19%) 50 0.43136 1 0.53269 1 0.18598 1 0.13891 1 0.58102 1 0.73958 1 1 1 1 1 0.14994 1 0.40461 1 1 1 TP53 13 (21%) 49 0.032907 1 0.91733 1 0.098329 1 0.23121 1 1 1 0.51549 1 1 1 1 1 0.0096099 1 0.40461 1 0.13462 1 CLDN23 10 (16%) 52 0.99727 1 0.716 1 0.62461 1 0.75213 1 0.25938 1 0.47182 1 1 1 0.21847 1 0.26502 1 0.70482 1 0.5585 1 GDF1 5 (8%) 57 0.10133 1 0.94844 1 0.37083 1 0.54878 1 1 1 1 1 0.58169 1 1 1 1 1 0.40461 1 1 1 LZTR1 6 (10%) 56 0.53616 1 0.46025 1 1 1 1 1 0.48412 1 1 1 0.13296 1 1 1 0.82714 1 0.94608 1 1 1 ANKRD43 19 (31%) 43 0.58704 1 0.37561 1 0.6242 1 0.79289 1 0.33789 1 0.39518 1 1 1 1 1 0.14287 1 0.40852 1 0.17797 1 KCNK17 9 (15%) 53 0.53954 1 0.71895 1 0.85092 1 0.42813 1 0.5847 1 0.70862 1 0.42341 1 1 1 0.55784 1 0.31034 1 0.18007 1 RINL 8 (13%) 54 0.36203 1 0.62153 1 0.61851 1 0.51472 1 1 1 0.70029 1 0.013155 1 1 1 0.70305 1 0.76786 1 0.26837 1 ZAR1 11 (18%) 51 0.28852 1 0.67156 1 0.65782 1 0.33222 1 0.3017 1 0.078935 1 0.70745 1 0.0166 1 0.80233 1 0.10454 1 0.5585 1 CTNNB1 8 (13%) 54 0.20764 1 0.3776 1 0.42896 1 0.48368 1 0.17805 1 0.04207 1 1 1 1 1 0.24307 1 0.94608 1 1 1 APOE 7 (11%) 55 0.84354 1 0.13307 1 1 1 0.91907 1 1 1 0.086091 1 0.13296 1 1 1 0.12647 1 NA NA 1 1 GPRIN2 8 (13%) 54 0.5789 1 0.40073 1 0.9443 1 0.58139 1 0.5847 1 1 1 0.37399 1 1 1 0.70263 1 0.40461 1 1 1 ASPDH 8 (13%) 54 0.40904 1 0.98324 1 0.00321 1 0.3126 1 0.1051 1 0.70029 1 0.0057317 1 1 1 0.12758 1 0.44866 1 1 1 ERCC2 10 (16%) 52 0.51974 1 0.83318 1 0.60137 1 0.63108 1 0.25938 1 1 1 0.22206 1 1 1 1 1 0.90056 1 0.5112 1 IDUA 8 (13%) 54 0.31883 1 0.20374 1 0.10928 1 0.23511 1 1 1 1 1 0.66686 1 0.43345 1 0.85621 1 0.40461 1 1 1 C1ORF106 9 (15%) 53 0.26574 1 0.38448 1 0.51435 1 0.30664 1 0.21798 1 0.14043 1 0.67052 1 1 1 1 1 0.94608 1 0.5585 1 C10ORF95 6 (10%) 56 0.56463 1 0.53569 1 0.35429 1 0.7065 1 1 1 1 1 1 1 0.11915 1 0.82662 1 NA NA 1 1 RGS9BP 8 (13%) 54 0.46553 1 0.98324 1 0.93758 1 0.03429 1 0.54144 1 0.43805 1 0.37399 1 1 1 1 1 0.54443 1 0.5112 1 THEM4 5 (8%) 57 0.67136 1 0.31312 1 0.47915 1 0.3865 1 0.35146 1 0.64731 1 1 1 1 1 0.72228 1 NA NA 1 1 TSC22D2 8 (13%) 54 0.021849 1 0.62897 1 0.27546 1 0.11512 1 1 1 0.70029 1 0.37399 1 0.16609 1 0.26142 1 0.40461 1 0.5112 1 SYT8 8 (13%) 54 0.34936 1 0.40665 1 0.22828 1 0.69302 1 0.5847 1 1 1 1 1 1 1 0.62418 1 NA NA 0.5585 1 PLIN5 5 (8%) 57 0.43431 1 0.58703 1 1 1 0.89487 1 0.42095 1 0.64731 1 0.077778 1 1 1 1 1 0.70482 1 0.37433 1 LRIG1 16 (26%) 46 0.62374 1 0.45908 1 0.91495 1 0.74759 1 0.15876 1 0.37529 1 0.73966 1 0.38044 1 0.75493 1 0.78675 1 0.64446 1 HHIPL1 6 (10%) 56 0.97715 1 0.60024 1 0.73072 1 0.64231 1 0.48412 1 0.65659 1 0.13296 1 1 1 0.6834 1 0.70482 1 1 1 CCDC105 6 (10%) 56 0.60467 1 0.43182 1 0.28033 1 0.10242 1 0.48412 1 0.080787 1 0.32006 1 1 1 1 1 NA NA 0.5112 1 C19ORF10 7 (11%) 55 0.92538 1 0.53323 1 0.14502 1 0.47953 1 0.54144 1 0.40475 1 0.33747 1 1 1 0.49292 1 0.94608 1 1 1 OPRD1 12 (19%) 50 0.90709 1 0.139 1 1 1 1 1 1 1 0.5123 1 0.44834 1 1 1 0.93633 1 0.95018 1 1 1 ATXN1 10 (16%) 52 0.84834 1 0.26265 1 0.74929 1 0.42802 1 1 1 0.082016 1 0.42664 1 1 1 0.26476 1 0.40461 1 1 1 AATK 6 (10%) 56 0.29852 1 0.034003 1 0.68089 1 0.7093 1 0.48412 1 0.40908 1 1 1 0.34331 1 1 1 NA NA 1 1 ZNF628 7 (11%) 55 0.022416 1 0.75539 1 0.43311 1 0.41313 1 1 1 1 1 0.61668 1 1 1 0.25982 1 NA NA 0.5112 1 KRTAP4-5 5 (8%) 57 0.13515 1 0.47692 1 0.57477 1 0.31407 1 1 1 0.64731 1 0.32876 1 1 1 1 1 NA NA 1 1 NOXA1 5 (8%) 57 0.21371 1 0.98968 1 0.89646 1 0.79641 1 0.42095 1 0.15097 1 1 1 1 1 1 1 0.40461 1 1 1 TRIOBP 10 (16%) 52 0.74873 1 0.76662 1 0.95214 1 1 1 0.052374 1 0.082016 1 0.68506 1 1 1 0.64117 1 0.40852 1 1 1 ZNF598 12 (19%) 50 0.37051 1 0.020975 1 0.51605 1 0.86457 1 0.58102 1 0.018637 1 1 1 0.58946 1 0.7991 1 0.31034 1 0.57981 1 IRX3 5 (8%) 57 0.63744 1 0.31312 1 0.23792 1 0.50776 1 1 1 0.64731 1 0.56418 1 1 1 0.081369 1 NA NA 1 1 WDR34 5 (8%) 57 0.5252 1 0.679 1 1 1 0.73913 1 1 1 0.049287 1 0.58169 1 0.29062 1 0.28663 1 NA NA 1 1 BHLHE22 5 (8%) 57 0.26374 1 0.92787 1 0.29129 1 0.8943 1 0.073514 1 0.64731 1 0.58169 1 1 1 0.050409 1 0.44866 1 0.18007 1 PANK2 5 (8%) 57 0.0097828 1 0.16644 1 0.896 1 0.62103 1 1 1 0.049287 1 1 1 1 1 0.04164 1 NA NA 1 1 FPGS 5 (8%) 57 0.13034 1 0.31936 1 0.23771 1 0.56267 1 0.42095 1 1 1 1 1 1 1 0.24838 1 NA NA 1 1 GLTPD2 6 (10%) 56 0.41171 1 0.10025 1 0.63353 1 0.62426 1 1 1 0.65659 1 0.13296 1 0.33821 1 0.40212 1 NA NA 0.20588 1 TNIP2 5 (8%) 57 0.42057 1 0.60496 1 0.085459 1 0.63803 1 0.046264 1 1 1 0.077778 1 1 1 0.72144 1 NA NA 1 1 AKAP2 6 (10%) 56 0.56415 1 0.88635 1 0.35639 1 0.91991 1 1 1 0.1736 1 1 1 0.33803 1 0.04431 1 NA NA 1 1 RREB1 5 (8%) 57 0.83897 1 0.93815 1 0.6332 1 0.23361 1 0.073514 1 1 1 0.58169 1 1 1 0.24657 1 0.26076 1 0.37433 1 TPO 12 (19%) 50 0.91438 1 0.85153 1 0.86367 1 0.95473 1 0.087936 1 1 1 0.26377 1 0.59113 1 1 1 0.21146 1 1 1 OBSCN 18 (29%) 44 0.83155 1 0.045341 1 0.43809 1 0.83902 1 0.33789 1 0.56134 1 0.19 1 0.67773 1 0.42432 1 0.69134 1 1 1 SNED1 5 (8%) 57 0.29555 1 0.73669 1 0.12949 1 0.15929 1 0.073514 1 0.64731 1 0.077778 1 1 1 1 1 NA NA 1 1 MEN1 5 (8%) 57 0.12836 1 0.6885 1 0.03297 1 0.15195 1 0.35146 1 1 1 0.58169 1 1 1 0.055269 1 NA NA 0.5112 1 BTBD11 6 (10%) 56 0.97568 1 0.86757 1 0.03655 1 0.14293 1 0.48412 1 0.40908 1 0.61668 1 1 1 1 1 0.44866 1 1 1 RNF149 4 (6%) 58 0.14255 1 0.070917 1 0.22981 1 0.3836 1 1 1 1 1 0.56418 1 1 1 1 1 NA NA 1 1 KIAA1984 4 (6%) 58 0.8698 1 0.6568 1 0.83415 1 0.51415 1 1 1 0.12354 1 0.22954 1 1 1 1 1 NA NA 0.5112 1 CCDC150 4 (6%) 58 0.099318 1 0.45607 1 0.03401 1 0.10556 1 0.35146 1 1 1 0.22954 1 1 1 0.078219 1 0.70482 1 0.1006 1 FAM18B2 4 (6%) 58 0.39014 1 0.62602 1 1 1 0.46366 1 0.35146 1 1 1 0.03639 1 1 1 0.72163 1 NA NA 0.37433 1 MUC5B 22 (35%) 40 0.61672 1 0.58097 1 0.73498 1 0.79974 1 0.4122 1 1 1 0.7514 1 0.21907 1 0.62804 1 0.086914 1 1 1 PTPLA 4 (6%) 58 0.6699 1 0.72009 1 0.60762 1 0.63655 1 1 1 0.61036 1 1 1 1 1 0.72073 1 NA NA 0.5112 1 SRPX 3 (5%) 59 0.82841 1 0.92157 1 0.83364 1 0.62531 1 0.27516 1 0.54627 1 0.5564 1 1 1 0.61047 1 0.44866 1 0.5112 1 GARS 19 (31%) 43 0.045806 1 0.22458 1 0.0082299 1 0.0065499 1 0.65793 1 1 1 0.045451 1 0.082099 1 0.37356 1 0.2352 1 0.64446 1 PRSS27 3 (5%) 59 0.2152 1 0.41193 1 0.46761 1 0.51544 1 1 1 0.28503 1 0.13296 1 1 1 0.61331 1 NA NA 0.037433 1 SEMA5B 8 (13%) 54 0.73145 1 0.64396 1 0.85172 1 1 1 1 1 0.43805 1 1 1 0.43467 1 0.43695 1 0.70482 1 1 1 CD320 4 (6%) 58 0.40205 1 0.28237 1 0.15114 1 0.26994 1 1 1 1 1 1 1 1 1 0.28468 1 NA NA 0.1006 1 TAF5 4 (6%) 58 0.36884 1 0.59588 1 0.31833 1 0.84307 1 0.35146 1 1 1 1 1 1 1 0.16155 1 NA NA 0.37433 1 NEFH 6 (10%) 56 0.23398 1 0.53569 1 1 1 0.37135 1 0.48412 1 1 1 0.61668 1 1 1 1 1 1 1 0.18007 1 DMKN 3 (5%) 59 0.18372 1 0.38445 1 NA NA NA NA 1 1 1 1 0.5564 1 1 1 NA NA NA NA 1 1 NPTX1 3 (5%) 59 0.88186 1 0.89555 1 0.24655 1 0.24145 1 1 1 0.28503 1 1 1 1 1 0.61397 1 NA NA 1 1 NOTCH2 5 (8%) 57 0.43915 1 0.76613 1 0.68525 1 0.46257 1 0.35146 1 1 1 0.077778 1 1 1 1 1 0.94608 1 1 1 RNF39 5 (8%) 57 0.83105 1 0.77602 1 0.31934 1 0.84396 1 0.35146 1 1 1 0.58169 1 1 1 0.28636 1 NA NA 0.37433 1 KBTBD13 9 (15%) 53 0.32805 1 0.49667 1 0.088489 1 0.11234 1 0.21798 1 0.14043 1 1 1 1 1 0.73876 1 0.34867 1 1 1 IER5 3 (5%) 59 0.00019899 0.254 0.58814 1 0.087779 1 0.03447 1 0.27516 1 0.54627 1 0.13296 1 1 1 0.088349 1 NA NA 1 1 SCRT1 3 (5%) 59 0.035315 1 0.22462 1 0.83228 1 0.32722 1 0.27516 1 0.54627 1 0.5564 1 1 1 0.17064 1 NA NA 1 1 KNDC1 9 (15%) 53 0.2964 1 0.91244 1 0.12953 1 0.068549 1 1 1 0.14043 1 1 1 1 1 1 1 0.40461 1 1 1 MAP1S 5 (8%) 57 0.71856 1 0.40058 1 0.38499 1 1 1 0.42095 1 0.3366 1 0.58169 1 0.29135 1 0.11814 1 NA NA 1 1 RGMB 6 (10%) 56 0.82693 1 0.72979 1 1 1 0.70898 1 0.48412 1 1 1 0.32006 1 1 1 1 1 NA NA 0.30578 1 LRP11 6 (10%) 56 0.62826 1 0.49721 1 0.75345 1 1 1 1 1 0.65659 1 1 1 1 1 0.6049 1 NA NA 0.5585 1 AR 4 (6%) 58 0.12749 1 0.78536 1 0.32188 1 0.15348 1 0.35146 1 1 1 1 1 0.23971 1 0.054379 1 NA NA 1 1 VARS 6 (10%) 56 0.99452 1 0.83955 1 0.31845 1 0.2324 1 1 1 0.1736 1 0.13296 1 1 1 1 1 0.40461 1 0.021132 1 SEZ6L2 8 (13%) 54 0.44015 1 0.88309 1 0.8504 1 0.61465 1 1 1 1 1 1 1 1 1 1 1 0.44866 1 0.30578 1 PABPC1 4 (6%) 58 0.62588 1 0.39774 1 1 1 1 1 0.35146 1 0.61036 1 1 1 1 1 1 1 NA NA 0.5585 1 FANK1 3 (5%) 59 0.79579 1 0.38445 1 0.01054 1 0.04846 1 0.27516 1 0.54627 1 1 1 1 1 0.61259 1 NA NA 1 1 NMU 5 (8%) 57 0.42693 1 0.27167 1 1 1 0.89584 1 0.42095 1 0.15097 1 0.58169 1 1 1 0.40244 1 0.54443 1 0.5112 1 ADAD2 4 (6%) 58 0.9917 1 0.62602 1 0.8345 1 1 1 1 1 0.12354 1 0.5564 1 0.073259 1 0.39207 1 NA NA 1 1 CLIC6 5 (8%) 57 0.28506 1 0.34515 1 0.47418 1 0.70597 1 1 1 0.64731 1 0.32876 1 1 1 1 1 NA NA 1 1 PCDHB13 5 (8%) 57 0.78437 1 0.12701 1 0.34786 1 0.20516 1 1 1 1 1 0.32876 1 1 1 0.40338 1 NA NA 0.1006 1 PLEC 13 (21%) 49 0.57113 1 0.56806 1 0.81904 1 0.79517 1 1 1 0.11215 1 0.47786 1 1 1 0.59753 1 1 1 0.64446 1 AMDHD1 10 (16%) 52 0.33015 1 0.043373 1 0.82302 1 1 1 0.57771 1 0.3066 1 0.19277 1 1 1 0.90682 1 NA NA 0.5112 1 DSPP 9 (15%) 53 0.85222 1 0.4124 1 0.69124 1 1 1 0.21798 1 0.47135 1 0.66686 1 1 1 0.66477 1 0.68489 1 1 1 TMEM189 3 (5%) 59 0.19293 1 0.44055 1 NA NA NA NA 1 1 1 1 0.5564 1 1 1 NA NA NA NA 0.37433 1 CRIPAK 10 (16%) 52 0.51419 1 0.11639 1 0.097339 1 0.32492 1 0.57679 1 1 1 0.097699 1 1 1 0.48971 1 NA NA 1 1 PDCD6 3 (5%) 59 0.78109 1 0.087891 1 0.01029 1 0.00461 1 0.27516 1 1 1 1 1 1 1 0.61457 1 NA NA 0.20588 1 MAP7 3 (5%) 59 0.97294 1 0.73039 1 1 1 1 1 1 1 1 1 0.5564 1 1 1 1 1 NA NA 1 1 NOM1 6 (10%) 56 0.93441 1 0.62532 1 0.20796 1 0.2585 1 1 1 1 1 0.32006 1 1 1 0.68642 1 NA NA 1 1 SHOX2 3 (5%) 59 0.20499 1 0.89555 1 1 1 0.78384 1 0.27516 1 1 1 0.5564 1 0.18571 1 1 1 NA NA 1 1 HSD17B1 4 (6%) 58 0.59018 1 0.59588 1 0.18481 1 0.22874 1 1 1 1 1 0.22954 1 1 1 0.50563 1 NA NA 0.37433 1 PRKAR1A 6 (10%) 56 0.90485 1 0.83025 1 0.060329 1 0.063309 1 0.48412 1 0.080787 1 1 1 1 1 0.68483 1 0.70482 1 0.37433 1 KRTAP5-5 3 (5%) 59 0.35918 1 0.066076 1 0.83323 1 1 1 1 1 0.28503 1 0.5564 1 1 1 1 1 NA NA 1 1 DLEU7 3 (5%) 59 0.39796 1 0.61096 1 0.83377 1 1 1 1 1 1 1 1 1 1 1 0.61235 1 NA NA 1 1 FEZ2 3 (5%) 59 0.73947 1 0.49069 1 0.83344 1 0.78486 1 0.27516 1 1 1 1 1 1 1 0.61259 1 NA NA 1 1 RASIP1 6 (10%) 56 0.11117 1 0.9905 1 0.64075 1 0.47611 1 0.48412 1 0.40908 1 0.61668 1 1 1 0.093179 1 NA NA 1 1 JMJD4 3 (5%) 59 0.90716 1 0.84389 1 1 1 0.62342 1 1 1 0.28503 1 1 1 1 1 0.3906 1 NA NA 0.37433 1 COQ2 5 (8%) 57 0.72077 1 0.12382 1 0.47149 1 0.70602 1 1 1 0.64731 1 1 1 0.29175 1 0.60267 1 NA NA 1 1 UQCRFS1 5 (8%) 57 0.25686 1 0.049335 1 0.03623 1 0.01992 1 0.42095 1 1 1 0.32876 1 1 1 0.04181 1 NA NA 0.18007 1 C9ORF66 5 (8%) 57 0.2451 1 0.35852 1 0.42815 1 0.56134 1 1 1 0.3366 1 0.58169 1 1 1 1 1 NA NA 0.037433 1 POLRMT 4 (6%) 58 0.10775 1 0.81861 1 0.22754 1 0.38583 1 1 1 0.61036 1 0.56418 1 0.23915 1 1 1 NA NA NA NA ADAMTS7 4 (6%) 58 0.15598 1 0.12868 1 0.22871 1 0.38606 1 1 1 1 1 1 1 0.24055 1 1 1 NA NA 1 1 BTNL9 4 (6%) 58 0.70187 1 0.50052 1 0.83474 1 1 1 1 1 1 1 1 1 1 1 0.39141 1 NA NA 1 1 NF1 7 (11%) 55 0.27859 1 0.68057 1 1 1 1 1 1 1 0.0064154 1 0.13296 1 1 1 0.2618 1 NA NA 0.5112 1 ZNF814 3 (5%) 59 0.23054 1 0.74276 1 0.02591 1 0.063659 1 1 1 1 1 1 1 1 1 0.16876 1 NA NA 1 1 RNF135 3 (5%) 59 0.20499 1 0.83107 1 0.57462 1 0.78153 1 1 1 1 1 1 1 1 1 1 1 NA NA 0.5112 1 CSGALNACT2 3 (5%) 59 0.83653 1 0.70586 1 0.83512 1 1 1 1 1 0.54627 1 1 1 1 1 0.61059 1 NA NA 1 1 SPIRE2 3 (5%) 59 0.82203 1 0.063693 1 0.38912 1 0.16028 1 1 1 0.54627 1 1 1 1 1 0.39525 1 NA NA 0.20588 1 CYP4A22 4 (6%) 58 0.066787 1 0.82977 1 0.31872 1 0.84409 1 1 1 0.61036 1 1 1 1 1 0.71886 1 NA NA 0.5112 1 HLA-A 3 (5%) 59 0.30716 1 0.22462 1 1 1 0.62365 1 1 1 0.28503 1 0.5564 1 1 1 1 1 NA NA 0.20588 1 GLI3 5 (8%) 57 0.11381 1 0.96905 1 0.01812 1 0.0065699 1 1 1 0.64731 1 0.58169 1 1 1 0.050859 1 NA NA 1 1