Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.043	0.251	0.497	2.0	-0.558	12.0	14.0
IHH	0.004	0.141	0.244	6.0	-0.466	4.0	10.0
SHH Np/Cholesterol/GAS1	-0.05	0.127	-9999.0	0.0	-0.267	18.0	18.0
LRPAP1	0.021	0.008	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.05	0.126	0.265	18.0	-9999.0	0.0	18.0
SMO/beta Arrestin2	-0.078	0.182	-9999.0	0.0	-0.418	7.0	7.0
SMO	-0.085	0.181	-9999.0	0.0	-0.37	14.0	14.0
AKT1	-0.041	0.132	-9999.0	0.0	-0.636	2.0	2.0
ARRB2	0.023	0.006	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.017	0.08	0.24	2.0	-0.428	2.0	4.0
ADRBK1	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.084	0.179	-9999.0	0.0	-0.366	14.0	14.0
STIL	-0.068	0.147	0.276	3.0	-0.291	11.0	14.0
DHH N/PTCH2	0.041	0.078	0.185	10.0	-0.309	2.0	12.0
DHH N/PTCH1	-0.011	0.141	0.318	1.0	-0.288	11.0	12.0
PIK3CA	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.035	0.103	0.24	9.0	-0.428	2.0	11.0
PTHLH	-0.099	0.354	0.699	1.0	-0.86	12.0	13.0
determination of left/right symmetry	-0.084	0.179	-9999.0	0.0	-0.366	14.0	14.0
PIK3R1	0.006	0.091	0.24	1.0	-0.428	3.0	4.0
skeletal system development	-0.098	0.35	0.698	1.0	-0.849	12.0	13.0
IHH N/Hhip	-0.026	0.168	0.237	3.0	-0.337	15.0	18.0
DHH N/Hhip	-0.003	0.147	0.199	11.0	-0.285	14.0	25.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.084	0.179	-9999.0	0.0	-0.366	14.0	14.0
pancreas development	-0.032	0.182	0.24	7.0	-0.427	12.0	19.0
HHAT	0.012	0.072	-9999.0	0.0	-0.428	2.0	2.0
PI3K	0.018	0.069	0.185	1.0	-0.309	3.0	4.0
EntrezGene:84976	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.004	0.115	0.24	1.0	-0.428	5.0	6.0
somite specification	-0.084	0.179	-9999.0	0.0	-0.366	14.0	14.0
SHH Np/Cholesterol/PTCH1	-0.062	0.15	0.312	2.0	-0.288	12.0	14.0
SHH Np/Cholesterol/PTCH2	-0.03	0.118	0.228	2.0	-0.249	15.0	17.0
SHH Np/Cholesterol/Megalin	-0.046	0.105	-9999.0	0.0	-0.245	15.0	15.0
SHH	-0.067	0.134	0.164	4.0	-0.32	15.0	19.0
catabolic process	-0.024	0.151	0.259	2.0	-0.323	13.0	15.0
SMO/Vitamin D3	-0.087	0.168	0.334	2.0	-0.329	13.0	15.0
SHH Np/Cholesterol/Hhip	-0.063	0.159	0.188	5.0	-0.278	23.0	28.0
LRP2	0.007	0.034	0.24	1.0	-9999.0	0.0	1.0
receptor-mediated endocytosis	-0.088	0.163	0.293	2.0	-0.388	6.0	8.0
SHH Np/Cholesterol/BOC	-0.038	0.116	0.151	1.0	-0.243	17.0	18.0
SHH Np/Cholesterol/CDO	-0.043	0.113	0.153	1.0	-0.24	18.0	19.0
mesenchymal cell differentiation	0.062	0.157	0.276	23.0	-0.186	5.0	28.0
mol:Vitamin D3	-0.057	0.161	0.327	3.0	-0.288	12.0	15.0
IHH N/PTCH2	0.025	0.094	0.217	2.0	-0.276	4.0	6.0
CDON	0.013	0.098	0.24	3.0	-0.428	3.0	6.0
IHH N/PTCH1	-0.008	0.167	0.366	2.0	-0.325	13.0	15.0
Megalin/LRPAP1	0.032	0.021	0.185	1.0	-9999.0	0.0	1.0
PTCH2	0.028	0.035	0.24	2.0	-9999.0	0.0	2.0
SHH Np/Cholesterol	-0.054	0.098	-9999.0	0.0	-0.243	15.0	15.0
PTCH1	-0.024	0.152	0.259	2.0	-0.324	13.0	15.0
HHIP	-0.032	0.182	0.24	7.0	-0.428	12.0	19.0