Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.046 0.219 0.334 1.0 -0.474 12.0 13.0 MAP3K8 0.015 0.081 0.247 2.0 -0.428 2.0 4.0 FOS -0.051 0.212 0.306 2.0 -0.477 11.0 13.0 PRKCA -0.018 0.133 0.24 1.0 -0.427 7.0 8.0 PTPN7 0.032 0.183 0.241 20.0 -0.429 8.0 28.0 HRAS 0.023 0.005 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.014 0.135 0.24 8.0 -0.43 5.0 13.0 NRAS 0.023 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.038 0.021 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.015 0.193 0.313 1.0 -0.541 7.0 8.0 MAP2K1 -0.058 0.193 -9999.0 0.0 -0.416 14.0 14.0 ELK1 0.022 0.014 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.046 0.165 -9999.0 0.0 -0.388 13.0 13.0 mol:GTP -0.0 0.001 0.003 2.0 -0.004 4.0 6.0 MAPK1 -0.062 0.222 0.281 1.0 -0.468 14.0 15.0 RAF1 -0.039 0.163 -9999.0 0.0 -0.39 12.0 12.0 KRAS 0.022 0.006 -9999.0 0.0 -9999.0 0.0 0.0