Hybridization REF	p	difference	q	subclass
Composite Element REF	p	difference	q	subclass
FN1|FIBRONECTIN	0.0160677832703803	1.26103033461538	0.118654399535116	1
RAD51|RAD51	0.000393269612990597	0.805420318019231	0.0188769414235487	1
SYK|SYK	0.0215750100307877	0.796485141019231	0.119610472279099	1
LCK|LCK	0.000245997457674622	0.609792429076923	0.0157438372911758	1
ANXA1|ANNEXIN-1	0.0170319674426279	0.557389674211539	0.119610472279099	1
HSPA1A|HSP70	0.00637486256826284	0.534232151923077	0.0764983508191541	1
COL6A1|COLLAGEN_VI	0.0062437562467784	0.505711620538462	0.0764983508191541	1
NFKB1|NF-KB-P65_PS536	0.00117287867657524	0.457181498134615	0.0375321176504077	1
CASP7|CASPASE-7_CLEAVEDD198	0.00568438677454934	0.349127997836538	0.0764983508191541	1
STMN1|STATHMIN	0.00306377303505323	0.343906311144231	0.0653604914144689	1
C12ORF5|TIGAR	0.0114789035180906	0.280549894125	0.11019747377367	1
MAP2K1|MEK1_PS217_S221	0.0204714952081562	0.276202071384615	0.119610472279099	1
EIF4EBP1|4E-BP1_PT70	0.0224269635523311	0.268812869855769	0.119610472279099	1
WWTR1|TAZ	0.0018410135215118	0.25805644675	0.0504963708757522	1
RPS6KA1|P90RSK_PT359_S363	0.0203518436839042	0.242565326817308	0.119610472279099	1
BID|BID	0.00775292792650934	0.241659212932692	0.0875624801111643	1
PIK3R1|PI3K-P85	0.0214472457955488	0.237793047538462	0.119610472279099	1
ACVRL1|ACVRL1	0.0275679952906572	0.234826181144231	0.126025121328719	1
RICTOR|RICTOR_PT1135	0.0190300667910262	0.208993270269231	0.119610472279099	1
CDH2|N-CADHERIN	0.0246017406164114	0.201638369432692	0.125264005285997	1
MRE11A|MRE11	0.0113187521862819	0.193980366519231	0.11019747377367	1
BRCA2|BRCA2	0.00483948898988649	0.178502632826923	0.0743075183674643	1
CHEK2|CHK2_PT68	0.0427257540113629	0.154619446836538	0.168948024947265	1
CDC2|CDK1	0.0431169438667499	-0.126251555163461	0.168948024947265	1
ERRFI1|MIG-6	0.0444548474129976	-0.156481930067308	0.170706614065911	1
PIK3CA |PI3K-P110-ALPHA	0.0267490844621139	-0.203606829028846	0.125264005285997	1
SCD1|SCD1	0.0194204708060498	-0.246065845923077	0.119610472279099	1
PARK7|DJ-1	0.00395237152262075	-0.26891012225	0.0743075183674643	1
FRAP1|MTOR	0.0316422592136293	-0.273168114144231	0.135006972644818	1
SHC1|SHC_PY317	3.1454973783043e-05	-0.282339949567308	0.00301967748317213	1
PRKAA1|AMPK_ALPHA	0.0147971187222079	-0.28671039025	0.118654399535116	1
MSH2|MSH2	0.00440495950800023	-0.325763140038462	0.0743075183674643	1
CCNE2|CYCLIN_E2	0.00953315200078637	-0.329577271990385	0.101686954675055	1
RPS6|S6	0.0124077582491295	-0.342964224384615	0.113442361134898	1
XRCC5|KU80	0.0156449564289656	-0.348219098057692	0.118654399535116	1
MSH6|MSH6	0.0311894744080105	-0.358767491144231	0.135006972644818	1
PKC|PKC-PAN_BETAII_PS660	0.0149162069615723	-0.378592971163462	0.118654399535116	1
BAP1|BAP1C-4	0.0258470030904762	-0.380234548567308	0.125264005285997	1
EEF2|EEF2	1.61136177689055e-05	-0.386349542682692	0.00301967748317213	1
ERCC1|ERCC1	0.0399011607404493	-0.387285855211538	0.163000486429069	1
TTF1|TTF1	0.00503123822279706	-0.390204860644231	0.0743075183674643	1
BRAF|B-RAF	0.0285754405120431	-0.400408096567308	0.127592664611913	1
EGFR|EGFR_PY1068	0.0332152020366197	-0.402591028596154	0.138637365022413	1
CDH1|E-CADHERIN	0.0264545033531287	-0.481392169423077	0.125264005285997	1
TSC2|TUBERIN	0.0182174900616787	-0.503679518192308	0.119610472279099	1
ACACA ACACB|ACC_PS79	0.00266517809949787	-0.522653300394231	0.0639642743879489	1
TP53BP1|53BP1	0.0218670345712495	-0.576398489173077	0.119610472279099	1
EEF2K|EEF2K	0.0260454062962908	-0.581938557576923	0.125264005285997	1
GATA3|GATA3	0.0135887969023375	-0.733770383519231	0.118593136602218	1
FASN|FASN	0.000557402060207108	-1.00068692125962	0.0214042391119529	1
FASN|FASN	0.0272581270188909	1.0805192073101	0.123162832583141	2
GSK3A GSK3B|GSK3-ALPHA-BETA_PS21_S9	1.43184820336558e-05	0.953191755665865	0.000916382850153971	2
PDCD4|PDCD4	0.0108975110826303	0.891881090348558	0.0721490388918972	2
GSK3A GSK3B|GSK3_PS9	0.00010085664743189	0.789170998685096	0.00387289526138458	2
AKT1 AKT2 AKT3|AKT_PS473	0.00419241085951116	0.760832446704327	0.0390007629880453	2
CDKN1A|P21	0.000291830220946369	0.700257534665865	0.00560314024217028	2
AKT1 AKT2 AKT3|AKT	0.0311413419773747	0.602500100579327	0.132869725770132	2
ACACA ACACB|ACC_PS79	0.000266912153952946	0.586057138771635	0.00560314024217028	2
ACACA|ACC1	0.00501279701177452	0.585145016887019	0.041845957663509	2
MAPK14|P38_PT180_Y182	0.0232963183005017	0.562323949723558	0.123162832583141	2
YAP1|YAP_PS127	0.0275833427139326	0.543630147194711	0.123162832583141	2
PTEN|PTEN	0.00426570845181745	0.520152524146635	0.0390007629880453	2
PKC|PKC-PAN_BETAII_PS660	0.0162487833344384	0.495588532742788	0.0974927000066304	2
AKT1 AKT2 AKT3|AKT_PT308	0.0332428098218303	0.485724498012019	0.135800414591307	2
CTNNB2|BETA-CATENIN	0.036589830291041	0.47712127815625	0.143372396242446	2
TSC2|TUBERIN	0.0131230875301249	0.433124157329327	0.0839877601927994	2
BAD|BAD_PS112	7.87021463218735e-05	0.412033459838942	0.00377770302344993	2
RPS6|S6_PS240_S244	0.0212665848601603	0.339174006963942	0.120093655680905	2
PRKAA1|AMPK_ALPHA	0.00911816662233297	0.256556283733173	0.0625245711245689	2
AKT1S1|PRAS40_PT246	0.00396493508483089	0.244632280877404	0.0390007629880453	2
FRAP1|MTOR_PS2448	0.00188549004456987	0.24275306903125	0.0212949463857303	2
EEF2|EEF2	0.0348409212852018	0.219826603079327	0.139363685140807	2
TSC2|TUBERIN_PT1462	0.000211697037546096	0.219152853021635	0.00560314024217028	2
XRCC5|KU80	0.0286170605472222	0.153378038512019	0.124874446024242	2
CDKN1B|P27_PT198	0.0457419490978107	-0.0672567481899039	0.168893350514993	2
XRCC1|XRCC1	0.0268974057576772	-0.0713417611322116	0.123162832583141	2
MS4A1|CD20	0.0229790910170805	-0.0773342369495193	0.123162832583141	2
RAF1|C-RAF_PS338	0.0169934693015718	-0.0830664794206731	0.0988710941182359	2
BECN1|BECLIN	0.0144479064260729	-0.105005756084135	0.0894838075421289	2
MAP2K1|MEK1_PS217_S221	0.0275329710893514	-0.118127486295673	0.123162832583141	2
STK11|LKB1	0.00832480043138985	-0.118440835911058	0.0591985808454389	2
MRE11A|MRE11	0.000532861133122116	-0.121708073689904	0.00852577812995386	2
ACVRL1|ACVRL1	0.0259217792950331	-0.13773122071875	0.123162832583141	2
YWHAB|14-3-3_BETA	0.00169711688485279	-0.145460865824519	0.0203654026182335	2
BRCA2|BRCA2	0.00237446606029024	-0.147978182516827	0.0253276379764292	2
PGR|PR	0.00106128805169399	-0.147998557305288	0.014554807566089	2
SMAD3|SMAD3	0.000172121179702602	-0.15869629859375	0.00550787775048326	2
BAK1|BAK	0.00527877081563423	-0.160426247161058	0.0422301665250738	2
INPP4B|INPP4B	0.0420903787148987	-0.162424712689904	0.161627054265211	2
CDH2|N-CADHERIN	0.0260415076025234	-0.180085884564904	0.123162832583141	2
ETS1|ETS-1	1.47146040713457e-06	-0.196084437612981	0.000168010732903146	2
CHEK2|CHK2_PT68	0.000326555901444341	-0.201431468295673	0.00569988482521032	2
CDH3|P-CADHERIN	0.0329514882773312	-0.203813108795673	0.135800414591307	2
CHEK1|CHK1	0.0445839667729368	-0.221396034151442	0.167845521968703	2
CASP7|CASPASE-7_CLEAVEDD198	0.000247248736106161	-0.241491213439904	0.00560314024217028	2
BIRC2 |CIAP	0.0267627735930673	-0.243549075334135	0.123162832583141	2
NRG1|HEREGULIN	0.00586026674828238	-0.273942214141827	0.0450068486268087	2
STMN1|STATHMIN	1.75011180107444e-06	-0.282270899132212	0.000168010732903146	2
TGM2|TRANSGLUTAMINASE	0.00483712852663299	-0.299959390141827	0.041845957663509	2
HSPA1A|HSP70	0.00658833756718309	-0.352572264805288	0.0486523389576597	2
LCK|LCK	0.0013494456121719	-0.379301795641827	0.0172729038358003	2
RAD51|RAD51	0.000918695673306547	-0.49550600859375	0.0135684284057582	2
PRKCA |PKC-ALPHA_PS657	0.000193303814018339	1.5291339588726	0.00742286645830422	3
PRKCA |PKC-ALPHA	0.000150837383509847	1.19006391932452	0.00724019440847266	3
CDH1|E-CADHERIN	0.00299469092592712	0.840832274055288	0.0258729137830744	3
PRKCD|PKC-DELTA_PS664	0.00086353083769485	0.744474542334135	0.013710759056133	3
VHL|VHL	0.00130393180595031	0.66590999459375	0.0144827297110801	3
RPS6KB1|P70S6K_PT389	0.00012489182344082	0.574179020478365	0.00724019440847266	3
STAT5A|STAT5-ALPHA	0.0407990138163224	0.561903446353365	0.146399061581793	3
TTF1|TTF1	0.00674568969943309	0.53314515046875	0.0462561579389698	3
TP53|P53	0.00340929921484192	0.479794744939904	0.0272743937187354	3
PRDX1|PRDX1	0.00135214998127741	0.450883390084135	0.0144827297110801	3
ESR1|ER-ALPHA	0.0133051664427263	0.435059508295673	0.0709608876945403	3
RAB25|RAB25	0.00964257842706611	0.427192272987981	0.0578554705623967	3
FOXO3|FOXO3A	0.00730687632047579	0.425030575430288	0.0483765604665983	3
PECAM1|CD31	0.0020539491535826	0.398848359997596	0.0195305451911616	3
CDH3|P-CADHERIN	0.0338234491347007	0.397903988661058	0.129882044677251	3
PREX1|PREX1	0.00861597528426209	0.309389009814904	0.0533634598251071	3
XBP1|XBP1	0.00484747572925705	0.307300395949519	0.0357967438468213	3
SCD1|SCD1	0.0021361533802833	0.303148413978365	0.0195305451911616	3
BCL2|BCL-2	0.0299366230241145	0.284209962103365	0.122294289800638	3
MYC|C-MYC	0.0147970989720024	0.27863358234375	0.0755400162746796	3
CDC2|CDK1	0.0493104260886819	0.267021031603365	0.16073694862776	3
SHC1|SHC_PY317	0.000999742847843033	0.246863382959135	0.013710759056133	3
ARHI|ARHI	0.029443604173119	0.226088005026442	0.122294289800638	3
NRAS|N-RAS	0.0117243058828886	0.20861629684375	0.064316192271846	3
CHEK1|CHK1_PS345	0.000621319474389449	0.167093969305288	0.0132548154536416	3
BAK1|BAK	0.0102912505088584	0.159438591997596	0.0598763665969943	3
YWHAB|14-3-3_BETA	0.000487453678587897	0.148481727007212	0.0116988882861095	3
PGR|PR	0.0356295497548796	0.138126895939904	0.134134775547782	3
MS4A1|CD20	0.0461145231605727	0.124836123747596	0.15533313064614	3
CDKN1B|P27_PT157	0.0151294670688548	0.121004850526442	0.0755400162746796	3
ESR1|ER-ALPHA_PS118	0.000957436206525333	0.0864993398725962	0.013710759056133	3
STK11|LKB1	0.0330391092279835	-0.140394236002404	0.129459366770874	3
MAP2K1|MEK1_PS217_S221	0.0153440658057943	-0.149677709223558	0.0755400162746796	3
EIF4EBP1|4E-BP1_PT70	0.0165786095643815	-0.15175601365625	0.0759169844758487	3
YAP1|YAP	0.0187168314310475	-0.164356961771635	0.0816734462445709	3
WWTR1|TAZ	0.00135775591041376	-0.179304926262019	0.0144827297110801	3
EIF4E|EIF4E	0.0308286267268714	-0.209844189694712	0.123314506907486	3
DVL3|DVL3	0.0158958822870717	-0.218645038012019	0.0759169844758487	3
BID|BID	0.00438603472301415	-0.221001179050481	0.0336847466727487	3
EIF4EBP1|4E-BP1_PS65	0.000248772682458125	-0.227793867175481	0.00796072583866	3
RPS6KB1|P70S6K	0.0280971219331012	-0.260021305002404	0.119881053581232	3
C12ORF5|TIGAR	0.0116121198268115	-0.286673472454327	0.064316192271846	3
GSK3A GSK3B|GSK3-ALPHA-BETA	0.0411747360698793	-0.289048224627404	0.146399061581793	3
RAF1|C-RAF	0.00660652046701515	-0.302236990060096	0.0462561579389698	3
TSC1|TSC1	0.0454087067725987	-0.312943711233173	0.15533313064614	3
KIT|C-KIT	0.0493931248387388	-0.320143699944712	0.16073694862776	3
RPS6|S6	0.0398260481058696	-0.327800365819712	0.146399061581793	3
COL6A1|COLLAGEN_VI	0.0170956895265872	-0.339415386060096	0.076334241607087	3
MYH9|MYOSIN-IIA-PS1943	0.0166068403540919	-0.406541766483173	0.0759169844758487	3
CCNB1|CYCLIN_B1	0.0449381541125844	-0.444447910973558	0.15533313064614	3
PTEN|PTEN	1.00467123435078e-05	-0.488908454060096	0.000964484384976749	3
MAPK1|ERK2	1.5948659365466e-06	-0.496675394262019	0.000306214259816947	3
RBM15|RBM15	0.00309935946359745	-0.530293692829327	0.0258729137830744	3
YAP1|YAP_PS127	0.0020166642441846	-0.670627713887019	0.0195305451911616	3
AKT1 AKT2 AKT3|AKT	0.00791902929468243	-0.755976867540865	0.0506817874859676	3
CTNNB2|BETA-CATENIN	0.00107220186426946	-0.793744013310096	0.0137241838626491	3
FASN|FASN	0.000839405982800196	-0.827883822194712	0.013710759056133	3
SERPINE1|PAI-1	0.000706592582826727	-0.934104162463942	0.0135665775902732	3
FN1|FIBRONECTIN	0.000316354634021243	-0.995400254877404	0.00867715567601124	3
CCNB1|CYCLIN_B1	0.0334499666783036	0.929752242425	0.176602294007692	4
CTNNB2|BETA-CATENIN	0.0070174105810806	0.761033002925	0.0863574661968371	4
CCNE1|CYCLIN_E1	0.000374324035910139	0.734075447658333	0.0239567382982489	4
FASN|FASN	0.0417752859237539	0.648311331325	0.183935738572702	4
RBM15|RBM15	0.0481595777560992	0.468968336325	0.183935738572702	4
EIF4G1|EIF4G	0.0478274536556864	0.423127105783333	0.183935738572702	4
TSC1|TSC1	0.0100829923904921	0.372722359483333	0.092036897328891	4
RPTOR|RAPTOR	0.0438910554251572	0.372531636358333	0.183935738572702	4
RPS6|S6	0.00448376358558267	0.369557017241667	0.0764045074945368	4
DVL3|DVL3	0.00689115772430874	0.364672795925	0.0863574661968371	4
GSK3A GSK3B|GSK3-ALPHA-BETA	0.00246161271137487	0.342703672491667	0.060049494898905	4
TSC2|TUBERIN	0.0308623868077056	0.334375949525	0.174281713737632	4
MAPK1|ERK2	0.0365246298088522	0.326177435566667	0.180905973334967	4
EEF2|EEF2	0.00196822363842608	0.300686229166667	0.060049494898905	4
YBX1|YB-1	0.0410714439324718	0.287415344466667	0.183935738572702	4
FRAP1|MTOR	0.0293537409625451	0.285328505066667	0.170785401963899	4
RPS6KB1|P70S6K	0.0175204405102234	0.280100230775	0.111301661947805	4
BAP1|BAP1C-4	0.00627179827301857	0.257170641616667	0.0863574661968371	4
RAF1|C-RAF	0.0378714640345659	0.227934067408333	0.180905973334967	4
CCNE2|CYCLIN_E2	0.0026832613128445	0.227699576175	0.060049494898905	4
SRC|SRC	0.045953871471374	0.192255444466667	0.183935738572702	4
EIF4EBP1|4E-BP1_PS65	0.0125037449876579	0.161643651258333	0.101091227902346	4
RAD50|RAD50	0.0481203107148008	0.122633348625	0.183935738572702	4
SMAD3|SMAD3	0.0105458944856021	0.11793958105	0.092036897328891	4
MET|C-MET_PY1235	0.00854579092572867	0.0796079799666667	0.0863574661968371	4
XRCC1|XRCC1	0.0496570272817418	0.0687428715583333	0.183935738572702	4
BRCA2|BRCA2	0.0328789856514133	-0.105524478125	0.176602294007692	4
RPS6KA1|P90RSK_PT359_S363	0.0340327337410657	-0.185360774366667	0.176602294007692	4
FRAP1|MTOR_PS2448	0.0164704135637183	-0.19670239705	0.111301661947805	4
PECAM1|CD31	0.0179705808353227	-0.203722541741667	0.111301661947805	4
ERBB2|HER2_PY1248	0.000239286582891095	-0.256760248016667	0.0229715119575451	4
PREX1|PREX1	0.0384335251151756	-0.265823776116667	0.180905973334967	4
BCL2|BCL-2	0.0154651215025885	-0.274752902508333	0.11035989824909	4
LCK|LCK	0.0083448760692046	-0.276651203075	0.0863574661968371	4
FOXO3|FOXO3A	0.00281482007338617	-0.29286113645	0.060049494898905	4
BAD|BAD_PS112	0.01707172356061	-0.301354280858333	0.111301661947805	4
MAPK1 MAPK3|MAPK_PT202_Y204	0.0155193606912783	-0.303001508316667	0.11035989824909	4
RPS6KB1|P70S6K_PT389	0.0015223161234128	-0.305230707266667	0.060049494898905	4
RAD51|RAD51	0.0425429368016909	-0.306963824483333	0.183935738572702	4
ESR1|ER-ALPHA	0.00376693632507995	-0.35697215	0.072325177441535	4
PRKCD|PKC-DELTA_PS664	0.0102559596819508	-0.370001543416667	0.092036897328891	4
SRC|SRC_PY416	0.00791042844906282	-0.381879529158333	0.0863574661968371	4
NFKB1|NF-KB-P65_PS536	0.00265588112456867	-0.409426068975	0.060049494898905	4
CDH1|E-CADHERIN	0.0083559211518399	-0.486837075816667	0.0863574661968371	4
MAPK14|P38_PT180_Y182	0.0386309630559044	-0.499504870741667	0.180905973334967	4
PKC|PKC-PAN_BETAII_PS660	0.0126364034877933	-0.518608896108333	0.101091227902346	4
ANXA1|ANNEXIN-1	3.74863267193757e-05	-0.541838433308333	0.00719737473012013	4
CDKN1A|P21	0.0276157243513961	-0.5915261818	0.165694346108377	4
SRC|SRC_PY527	0.0477938681372091	-0.605807355125	0.183935738572702	4
PRKCA |PKC-ALPHA_PS657	0.0140471752640564	-1.06068863085833	0.107882306027953	4
NDRG1|NDRG1_PT346	0.00477528171840855	-1.40632133545833	0.0764045074945368	4