Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.041 0.145 0.419 52.0 -9999.0 0.0 52.0 KIRREL -0.053 0.188 -9999.0 0.0 -0.579 46.0 46.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.041 0.146 -9999.0 0.0 -0.42 52.0 52.0 PLCG1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.044 0.118 -9999.0 0.0 -0.33 46.0 46.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.007 0.103 -9999.0 0.0 -0.3 25.0 25.0 FYN -0.029 0.121 -9999.0 0.0 -0.322 47.0 47.0 mol:Ca2+ -0.048 0.114 -9999.0 0.0 -0.327 46.0 46.0 mol:DAG -0.049 0.115 -9999.0 0.0 -0.328 46.0 46.0 NPHS2 -0.023 0.11 -9999.0 0.0 -0.515 19.0 19.0 mol:IP3 -0.049 0.115 -9999.0 0.0 -0.328 46.0 46.0 regulation of endocytosis -0.018 0.114 -9999.0 0.0 -0.331 25.0 25.0 Nephrin/NEPH1/podocin/Cholesterol -0.04 0.124 -9999.0 0.0 -0.311 66.0 66.0 establishment of cell polarity -0.041 0.145 -9999.0 0.0 -0.419 52.0 52.0 Nephrin/NEPH1/podocin/NCK1-2 -0.013 0.116 -9999.0 0.0 -0.46 7.0 7.0 Nephrin/NEPH1/beta Arrestin2 -0.017 0.116 -9999.0 0.0 -0.335 25.0 25.0 NPHS1 -0.008 0.064 -9999.0 0.0 -0.498 6.0 6.0 Nephrin/NEPH1/podocin -0.029 0.121 -9999.0 0.0 -0.324 47.0 47.0 TJP1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.044 0.118 -9999.0 0.0 -0.33 46.0 46.0 CD2AP 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.044 0.118 -9999.0 0.0 -0.33 46.0 46.0 GRB2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.025 0.121 -9999.0 0.0 -0.314 47.0 47.0 cytoskeleton organization -0.007 0.12 -9999.0 0.0 -0.472 7.0 7.0 Nephrin/NEPH1 -0.027 0.104 -9999.0 0.0 -0.297 52.0 52.0 Nephrin/NEPH1/ZO-1 -0.042 0.109 -9999.0 0.0 -0.335 46.0 46.0