Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.096 0.198 0.627 121.0 -9999.0 0.0 121.0 KIRREL -0.079 0.252 -9999.0 0.0 -0.794 121.0 121.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.096 0.199 -9999.0 0.0 -0.628 121.0 121.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.07 0.15 -9999.0 0.0 -0.479 121.0 121.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.043 0.112 -9999.0 0.0 -0.358 121.0 121.0 FYN -0.065 0.144 -9999.0 0.0 -0.458 121.0 121.0 mol:Ca2+ -0.069 0.149 -9999.0 0.0 -0.474 121.0 121.0 mol:DAG -0.069 0.15 -9999.0 0.0 -0.476 121.0 121.0 NPHS2 -0.008 0.031 -9999.0 0.0 -0.29 5.0 5.0 mol:IP3 -0.069 0.15 -9999.0 0.0 -0.476 121.0 121.0 regulation of endocytosis -0.055 0.136 -9999.0 0.0 -0.426 121.0 121.0 Nephrin/NEPH1/podocin/Cholesterol -0.072 0.153 -9999.0 0.0 -0.487 121.0 121.0 establishment of cell polarity -0.096 0.198 -9999.0 0.0 -0.627 121.0 121.0 Nephrin/NEPH1/podocin/NCK1-2 -0.062 0.136 -9999.0 0.0 -0.435 121.0 121.0 Nephrin/NEPH1/beta Arrestin2 -0.056 0.138 -9999.0 0.0 -0.432 121.0 121.0 NPHS1 -0.047 0.111 -9999.0 0.0 -0.293 177.0 177.0 Nephrin/NEPH1/podocin -0.065 0.145 -9999.0 0.0 -0.46 121.0 121.0 TJP1 -0.001 0.024 -9999.0 0.0 -0.787 1.0 1.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.07 0.15 -9999.0 0.0 -0.479 121.0 121.0 CD2AP -0.0 0.009 -9999.0 0.0 -0.293 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 -0.07 0.15 -9999.0 0.0 -0.479 121.0 121.0 GRB2 -0.0 0.009 -9999.0 0.0 -0.293 1.0 1.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.057 0.175 -9999.0 0.0 -0.498 130.0 130.0 cytoskeleton organization -0.055 0.139 -9999.0 0.0 -0.444 121.0 121.0 Nephrin/NEPH1 -0.069 0.148 -9999.0 0.0 -0.471 121.0 121.0 Nephrin/NEPH1/ZO-1 -0.076 0.163 -9999.0 0.0 -0.518 121.0 121.0