Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.04	0.22	0.412	5.0	-0.627	113.0	118.0
IHH	0.016	0.082	0.264	31.0	-0.216	37.0	68.0
SHH Np/Cholesterol/GAS1	0.0	0.075	-9999.0	0.0	-0.328	49.0	49.0
LRPAP1	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	-0.0	0.075	0.326	49.0	-9999.0	0.0	49.0
SMO/beta Arrestin2	-0.019	0.209	-9999.0	0.0	-0.619	97.0	97.0
SMO	-0.042	0.212	0.319	1.0	-0.653	97.0	98.0
AKT1	-0.004	0.133	-9999.0	0.0	-0.594	25.0	25.0
ARRB2	0.022	0.007	-9999.0	0.0	-9999.0	0.0	0.0
BOC	-0.018	0.151	-9999.0	0.0	-0.566	76.0	76.0
ADRBK1	0.023	0.006	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.041	0.208	0.318	1.0	-0.639	97.0	98.0
STIL	0.006	0.173	0.296	31.0	-0.476	87.0	118.0
DHH N/PTCH2	-0.008	0.14	-9999.0	0.0	-0.442	97.0	97.0
DHH N/PTCH1	-0.027	0.205	-9999.0	0.0	-0.506	144.0	144.0
PIK3CA	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.008	0.096	0.255	2.0	-0.566	29.0	31.0
PTHLH	-0.061	0.297	0.428	10.0	-0.828	120.0	130.0
determination of left/right symmetry	-0.041	0.208	0.318	1.0	-0.639	97.0	98.0
PIK3R1	0.016	0.065	-9999.0	0.0	-0.566	13.0	13.0
skeletal system development	-0.059	0.293	0.42	14.0	-0.816	120.0	134.0
IHH N/Hhip	0.027	0.056	0.235	2.0	-0.458	2.0	4.0
DHH N/Hhip	0.022	0.077	-9999.0	0.0	-0.414	31.0	31.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.041	0.208	0.318	1.0	-0.639	97.0	98.0
pancreas development	0.023	0.03	0.255	5.0	-0.565	2.0	7.0
HHAT	0.02	0.02	-9999.0	0.0	-0.566	1.0	1.0
PI3K	0.028	0.049	-9999.0	0.0	-0.385	14.0	14.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.009	0.137	-9999.0	0.0	-0.566	61.0	61.0
somite specification	-0.041	0.208	0.318	1.0	-0.639	97.0	98.0
SHH Np/Cholesterol/PTCH1	-0.024	0.159	0.257	4.0	-0.479	97.0	101.0
SHH Np/Cholesterol/PTCH2	-0.004	0.082	-9999.0	0.0	-0.329	59.0	59.0
SHH Np/Cholesterol/Megalin	-0.06	0.147	0.277	3.0	-0.329	228.0	231.0
SHH	-0.0	0.037	0.341	7.0	-0.423	1.0	8.0
catabolic process	-0.033	0.208	0.311	2.0	-0.571	123.0	125.0
SMO/Vitamin D3	-0.009	0.198	0.363	15.0	-0.574	88.0	103.0
SHH Np/Cholesterol/Hhip	0.015	0.028	0.248	3.0	-0.333	3.0	6.0
LRP2	-0.123	0.264	0.255	26.0	-0.566	277.0	303.0
receptor-mediated endocytosis	-0.079	0.221	0.303	11.0	-0.622	101.0	112.0
SHH Np/Cholesterol/BOC	-0.004	0.083	-9999.0	0.0	-0.329	61.0	61.0
SHH Np/Cholesterol/CDO	0.013	0.04	-9999.0	0.0	-0.33	12.0	12.0
mesenchymal cell differentiation	-0.015	0.028	0.331	3.0	-0.245	3.0	6.0
mol:Vitamin D3	0.002	0.181	0.344	21.0	-0.49	93.0	114.0
IHH N/PTCH2	-0.006	0.137	-9999.0	0.0	-0.47	76.0	76.0
CDON	0.015	0.065	-9999.0	0.0	-0.566	13.0	13.0
IHH N/PTCH1	-0.024	0.214	0.35	4.0	-0.575	123.0	127.0
Megalin/LRPAP1	-0.079	0.201	-9999.0	0.0	-0.418	277.0	277.0
PTCH2	-0.018	0.151	-9999.0	0.0	-0.566	76.0	76.0
SHH Np/Cholesterol	0.01	0.013	-9999.0	0.0	-0.329	1.0	1.0
PTCH1	-0.033	0.209	0.312	2.0	-0.574	123.0	125.0
HHIP	0.023	0.03	0.255	5.0	-0.566	2.0	7.0