Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.056 0.202 0.29 1.0 -0.392 192.0 193.0 MAP3K8 0.009 0.051 -9999.0 0.0 -0.57 7.0 7.0 FOS -0.02 0.142 0.287 2.0 -0.445 52.0 54.0 PRKCA -0.002 0.086 0.235 1.0 -0.574 22.0 23.0 PTPN7 0.021 0.06 0.245 61.0 -9999.0 0.0 61.0 HRAS 0.024 0.022 0.254 9.0 -9999.0 0.0 9.0 PRKCB 0.006 0.079 0.247 19.0 -0.575 15.0 34.0 NRAS 0.023 0.004 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.025 0.036 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.008 0.09 -9999.0 0.0 -0.656 7.0 7.0 MAP2K1 -0.012 0.12 -9999.0 0.0 -0.502 45.0 45.0 ELK1 0.006 0.029 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.012 0.099 -9999.0 0.0 -0.48 39.0 39.0 mol:GTP -0.002 0.003 -9999.0 0.0 -0.006 323.0 323.0 MAPK1 -0.009 0.122 -9999.0 0.0 -0.471 41.0 41.0 RAF1 -0.011 0.097 -9999.0 0.0 -0.475 39.0 39.0 KRAS 0.022 0.005 -9999.0 0.0 -9999.0 0.0 0.0