Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.026 0.081 0.265 29.0 -9999.0 0.0 29.0 KIRREL -0.025 0.109 -9999.0 0.0 -0.406 23.0 23.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.026 0.081 -9999.0 0.0 -0.266 29.0 29.0 PLCG1 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.017 0.057 -9999.0 0.0 -0.206 23.0 23.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.001 0.059 -9999.0 0.0 -0.205 23.0 23.0 FYN -0.01 0.06 -9999.0 0.0 -0.191 28.0 28.0 mol:Ca2+ -0.017 0.056 -9999.0 0.0 -0.205 23.0 23.0 mol:DAG -0.017 0.056 -9999.0 0.0 -0.206 23.0 23.0 NPHS2 -0.002 0.012 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.017 0.056 -9999.0 0.0 -0.206 23.0 23.0 regulation of endocytosis -0.014 0.054 -9999.0 0.0 -0.184 23.0 23.0 Nephrin/NEPH1/podocin/Cholesterol -0.019 0.058 -9999.0 0.0 -0.211 23.0 23.0 establishment of cell polarity -0.026 0.081 -9999.0 0.0 -0.265 29.0 29.0 Nephrin/NEPH1/podocin/NCK1-2 -0.012 0.051 -9999.0 0.0 -0.182 23.0 23.0 Nephrin/NEPH1/beta Arrestin2 -0.003 0.057 -9999.0 0.0 -0.185 23.0 23.0 NPHS1 -0.006 0.042 -9999.0 0.0 -0.254 8.0 8.0 Nephrin/NEPH1/podocin -0.016 0.058 -9999.0 0.0 -0.192 28.0 28.0 TJP1 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.017 0.057 -9999.0 0.0 -0.206 23.0 23.0 CD2AP 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.017 0.057 -9999.0 0.0 -0.206 23.0 23.0 GRB2 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.007 0.058 -9999.0 0.0 -0.189 26.0 26.0 cytoskeleton organization 0.002 0.062 -9999.0 0.0 -0.212 23.0 23.0 Nephrin/NEPH1 -0.018 0.055 -9999.0 0.0 -0.201 23.0 23.0 Nephrin/NEPH1/ZO-1 -0.019 0.061 -9999.0 0.0 -0.225 23.0 23.0