Hybridization REF	p	difference	q	subclass
Composite Element REF	p	difference	q	subclass
HSPA1A|HSP70	6.43682949614489e-05	1.15782978761711	0.00454665867569092	1
MYH11|MYH11	0.0360449430330204	0.949694287338158	0.150448457876955	1
FN1|FIBRONECTIN	0.0130817772664957	0.930354698132895	0.0761121586414295	1
MAPK14|P38_PT180_Y182	0.000409030379201084	0.767968145359211	0.00872598142295646	1
CCND1|CYCLIN_D1	0.000882080707726659	0.527707044764474	0.0122649867289359	1
RICTOR|RICTOR_PT1135	0.00489797690462007	0.432587544043421	0.040887459377698	1
CASP7|CASPASE-7_CLEAVEDD198	0.0163922483564864	0.412198508722368	0.0874253245679275	1
NRG1|HEREGULIN	0.0495571162746963	0.412125163485526	0.17044979541929	1
BID|BID	0.00753810395550618	0.394694830148684	0.0571519122640875	1
MAP2K1|MEK1_PS217_S221	0.000966584624391553	0.386353048648684	0.0123722831922119	1
STMN1|STATHMIN	0.00634367547205347	0.354046983790789	0.0507494037764278	1
RAB11A RAB11B|RAB11	0.000618140596991672	0.295342204122368	0.010789363147491	1
STAT3|STAT3_PY705	0.00773932145242852	0.288991586348684	0.0571519122640875	1
STK11|LKB1	0.000248448655162532	0.284808578359211	0.00623657181991591	1
YWHAZ|14-3-3_ZETA	0.023191797524089	0.280885156101316	0.111320628115627	1
LCK|LCK	0.0466382058627246	0.272306013164474	0.17044979541929	1
RAF1|C-RAF_PS338	0.00141106439206257	0.209731067959211	0.0152268931511363	1
EIF4EBP1|4E-BP1_PT70	0.049392998534848	0.209255941722368	0.17044979541929	1
CHEK2|CHK2_PT68	0.0121197934930715	0.176015092206579	0.075064527440959	1
ERBB3|HER3_PY1289	0.000483021227156343	0.172036320696053	0.00927400756140179	1
MET|C-MET_PY1235	0.0296633944250016	0.100966778690789	0.135604088800007	1
CDKN1B|P27_PT157	0.0216542788453252	-0.149379191382895	0.108831903546783	1
ESR1|ER-ALPHA_PS118	0.00146965976529285	-0.156692011740789	0.0152268931511363	1
CTNNB1|ALPHA-CATENIN	0.0348637061199407	-0.161544964782895	0.148751812778414	1
CHEK1|CHK1_PS345	0.0144276922572113	-0.168197536998684	0.0791461975252734	1
EGFR|EGFR	0.0471810371048955	-0.178991151677632	0.17044979541929	1
CCNE2|CYCLIN_E2	7.54026326228774e-05	-0.183999305877632	0.00454665867569092	1
ADAR|ADAR1	0.000150474541030473	-0.189005071214474	0.00481518531297514	1
BCL2|BCL-2	0.0190985697104964	-0.196021949051316	0.099106091470684	1
JUN|C-JUN_PS73	0.0119995942082399	-0.211698129425	0.075064527440959	1
AR|AR	0.000122907515653823	-0.226782286046053	0.0047196486011068	1
DVL3|DVL3	0.0386237233642	-0.250997637751316	0.157782018849498	1
TP53|P53	0.0221064804079403	-0.282591167135526	0.108831903546783	1
EIF4EBP1|4E-BP1	0.0437738266127154	-0.311142585382895	0.17044979541929	1
EGFR|EGFR_PY1068	0.00429576879565969	-0.351494371161842	0.03749034585303	1
COPS5|JAB1	0.00971265755505307	-0.365158139614474	0.0690677870581552	1
RPS6|S6	0.0325745436543448	-0.399901847935526	0.143534184083204	1
FRAP1|MTOR	0.00222139696614955	-0.403244452703947	0.0213254108750357	1
MSH2|MSH2	0.00290203862300442	-0.413642448319737	0.0265329245531833	1
PRKCA |PKC-ALPHA_PS657	0.0465687789069755	-0.439479686261842	0.17044979541929	1
ERBB2|HER2	0.00141093652757448	-0.453096229335526	0.0152268931511363	1
PRKCD|PKC-DELTA_PS664	0.000894321948984907	-0.461350417835526	0.0122649867289359	1
SHC1|SHC_PY317	9.47220557435609e-05	-0.465522621361842	0.00454665867569092	1
TP53BP1|53BP1	0.0115506428960003	-0.528867934282895	0.075064527440959	1
PTEN|PTEN	0.0399909378738299	-0.534046284682895	0.15996375149532	1
RPS6KB1|P70S6K	0.0130149603452766	-0.545540373219737	0.0761121586414295	1
STAT5A|STAT5-ALPHA	0.0459683468108747	-0.586320228698684	0.17044979541929	1
TSC2|TUBERIN	0.0276691249660542	-0.587054952677632	0.129572487645912	1
BAP1|BAP1-C-4	0.0015068279680812	-0.591089734509211	0.0152268931511363	1
RBM15|RBM15	0.0117607126311707	-0.604672856514474	0.075064527440959	1
EEF2K|EEF2K	1.89230803989539e-06	-0.691765196867105	0.000363323143659915	1
PXN|PAXILLIN	0.000259857159163163	-0.730776011335526	0.00623657181991591	1
CDH1|E-CADHERIN	0.0328932505190676	-0.816496193472368	0.143534184083204	1
CTNNB2|BETA-CATENIN	0.01421507340507	-0.825137748798684	0.0791461975252734	1
EIF4G1|EIF4G	0.000882563722040937	-0.928671490588158	0.0122649867289359	1
RPS6|S6_PS235_S236	0.000397994964386635	1.03479643323214	0.00416971586810697	2
RPS6|S6_PS240_S244	0.000325347119978381	0.976892955035714	0.00390416543974057	2
NDRG1|NDRG1_PT346	0.0018089191528709	0.892233557107143	0.00913980203555823	2
COPS5|JAB1	0.000424188328145381	0.821479619880952	0.00416971586810697	2
MSH2|MSH2	0.000172859482465726	0.76865292664881	0.00332318757737426	2
EGFR|EGFR_PY1068	0.000434345402927809	0.731199383976191	0.00416971586810697	2
AKT1 AKT2 AKT3|AKT_PS473	4.29923477012787e-05	0.688124832541667	0.00137575512644092	2
ESR1|ER-ALPHA	0.00415317655103629	0.662739011952381	0.0166127062041452	2
SRC|SRC_PY416	0.000623309415774537	0.639021873279762	0.00532533158687906	2
TP53|P53	0.00114360422488365	0.636028814708334	0.00708296810250519	2
CDKN1A|P21	0.0194345690912296	0.620230488005952	0.0538541889450558	2
ARHI|ARHI	0.000669168192877887	0.582666125095238	0.0053533455430231	2
MAPK1 MAPK3|MAPK_PT202_Y204	0.000207699223585891	0.568636605410714	0.00332318757737426	2
BAP1|BAP1-C-4	0.000724220328916741	0.528197194113095	0.00550048562495219	2
JUN|C-JUN_PS73	4.25883342370169e-05	0.503931272392857	0.00137575512644092	2
SCD1|SCD1	0.00177409172412792	0.459336782845238	0.00913980203555823	2
SFRS1|SF2	0.000274074439685401	0.445676392922619	0.00375873517282836	2
TSC2|TUBERIN_PT1462	0.000183253783145778	0.401797743428571	0.00332318757737426	2
SMAD4|SMAD4	0.00200354137011519	0.390383688779762	0.00961699857655291	2
EIF4G1|EIF4G	0.034544198471468	0.389951578613095	0.0799094711629139	2
ARAF|A-RAF_PS299	0.00207277396780463	0.385672448511905	0.00970664882484119	2
INPP4B|INPP4B	0.00175827692461275	0.370260537333333	0.00913980203555823	2
SHC1|SHC_PY317	0.000264583719260592	0.365901731916667	0.00375873517282836	2
FRAP1|MTOR_PS2448	0.000879802428304628	0.362860591267857	0.00563073554114962	2
GSK3A GSK3B|GSK3_PS9	0.0132530338484557	0.345215774660714	0.0410416532081209	2
PECAM1|CD31	0.00187898946353508	0.343395516464286	0.00925040966663424	2
FOXO3|FOXO3A	0.00163207168850031	0.320431839595238	0.00895307897691599	2
FOXM1|FOXM1	0.00457998518517338	0.319722336678571	0.0175871431110658	2
GSK3A GSK3B|GSK3-ALPHA-BETA_PS21_S9	0.0217702900964956	0.317854521910714	0.0582619203208016	2
BCL2|BCL-2	0.00350068016767226	0.317181731946429	0.014300650897725	2
BAK1|BAK	0.0196343397195516	0.314719086375	0.0538541889450558	2
ANXA1|ANNEXIN_1	0.00890269790685155	0.309125522565476	0.0294709999675086	2
RB1|RB_PS807_S811	0.0262595332743829	0.300759702785714	0.0631798763131997	2
CDKN1B|P27_PT157	0.00129785636780274	0.265349732732143	0.0075511643217614	2
PRDX1|PRDX1	0.0244644972423938	0.257004849458333	0.0626291129405281	2
RPS6KA1|P90RSK_PT359_S363	0.0249392548796451	0.249139345916667	0.0629397752956311	2
AKT1 AKT2 AKT3|AKT_PT308	0.0263249484638332	0.24884676275	0.0631798763131997	2
CDH2|N-CADHERIN	0.0362126999880989	0.221673285839286	0.0821858446991968	2
NOTCH1|NOTCH1	0.0183476403361399	0.213832970839286	0.0525783126050576	2
ACVRL1|ACVRL1	0.0239296544532662	0.191348390934524	0.062087752094961	2
YWHAE|14-3-3_EPSILON	0.00330276898742995	0.190531262696428	0.0137854705562294	2
CTNNB1|ALPHA-CATENIN	0.000784602562202858	0.190508667892857	0.00550048562495219	2
CHEK2|CHK2	0.0333593234378125	0.169848238625	0.0781096353665854	2
NRAS|N-RAS	0.0331007643695873	0.158454706755952	0.0781096353665854	2
ADAR|ADAR1	0.00437969112352167	0.156491143422619	0.0171612386880849	2
TTF1|TTF1	0.039501939496245	0.153810225244048	0.0871766940606786	2
BAD|BAD_PS112	0.0363843583303736	0.15254058914881	0.0821858446991968	2
CHEK1|CHK1_PS345	0.013849086174682	0.143562648440476	0.0422067388180785	2
ERCC1|ERCC1	0.0258256700201892	0.137149919541667	0.0631798763131997	2
ETS1|ETS-1	0.0232174162620401	0.130443496041667	0.0610649852371466	2
MAPK8|JNK_PT183_PY185	0.0179503178993484	0.125801285005952	0.0522191066162863	2
RAF1|C-RAF	0.0496094914519578	-0.121623418077381	0.107022723132313	2
CHEK1|CHK1	0.017062012598688	-0.129615094577381	0.0503985602915092	2
PARK7|DJ-1	0.0434751331099211	-0.139850667553571	0.0948548358761915	2
WWTR1|TAZ	0.00556966703639399	-0.154991640517857	0.0205649244420701	2
EIF4E|EIF4E	0.0218482201203006	-0.174202402059524	0.0582619203208016	2
STMN1|STATHMIN	0.0160930271939159	-0.176755323672619	0.0482790815817477	2
YAP1|YAP	0.000320311068543377	-0.19631375977381	0.00390416543974057	2
ERBB3|HER3_PY1289	9.36250484800007e-06	-0.206368553047619	0.000717258280157462	2
MAP2K1|MEK1_PS217_S221	0.0252414723841854	-0.207107505232143	0.0629397752956311	2
NRG1|HEREGULIN	0.0369910738247988	-0.221165829761905	0.0825847229576903	2
STK11|LKB1	1.49428808366138e-05	-0.236673068005952	0.000717258280157462	2
EGFR|EGFR_PY1173	0.00228359755058307	-0.240153266833333	0.0104393030883797	2
KDR|VEGFR2	0.00640969515727729	-0.249178991958333	0.0227900272258748	2
EIF4EBP1|4E-BP1_PS65	0.000156060932144009	-0.254964914160714	0.00332318757737426	2
XRCC1|XRCC1	0.00312878413325073	-0.259246677529762	0.013547744529022	2
SMAD1|SMAD1	0.000508847479859578	-0.265484545934524	0.004652319815859	2
PDK1|PDK1	0.0112438358217316	-0.271931803946429	0.0353904340618437	2
PRKAA1|AMPK_ALPHA	0.00838921177913295	-0.324307831297619	0.0287143367726307	2
RICTOR|RICTOR_PT1135	0.000830802516268821	-0.331437183589286	0.00550048562495219	2
RPTOR|RAPTOR	0.0012968764667317	-0.335652594857143	0.0075511643217614	2
PDK1|PDK1_PS241	0.00551871855434813	-0.356122695553571	0.0205649244420701	2
PIK3R1|PI3K-P85	1.17175356657145e-05	-0.357660274029762	0.000717258280157462	2
SMAD3|SMAD3	0.00306712889018271	-0.363743385464286	0.013547744529022	2
SRC|SRC	0.00841696274306299	-0.374258262547619	0.0287143367726307	2
PEA15|PEA15	0.0101224000592116	-0.376947663630952	0.0325190472631056	2
RAB11A RAB11B|RAB11	0.000827759133483379	-0.379060890738095	0.00550048562495219	2
ERBB2|HER2_PY1248	0.00136296721303831	-0.392097767130952	0.00769675602656928	2
GSK3A GSK3B|GSK3-ALPHA-BETA	0.000637930346344888	-0.41138547714881	0.00532533158687906	2
YWHAZ|14-3-3_ZETA	0.00852456872937473	-0.417432872279762	0.0287143367726307	2
BID|BID	3.0600453767639e-06	-0.458880643422619	0.000587528712338669	2
TSC1|TSC1	0.0101622022697205	-0.466359014761905	0.0325190472631056	2
BAX|BAX	6.6933033416019e-05	-0.525020656136905	0.00183587748798224	2
ACACA|ACC1	0.00317525262398954	-0.554844691541667	0.013547744529022	2
MAPK14|P38	0.000198636663453265	-0.580883939446429	0.00332318757737426	2
BCL2L1|BCL-XL	0.000401007201878597	-0.714743986696429	0.00416971586810697	2
HSPA1A|HSP70	0.000810256103023054	-0.785334158297619	0.00550048562495219	2
SERPINE1|PAI-1	0.0193506467188244	-0.902944203589286	0.0538541889450558	2
MYH11|MYH11	0.00639238536268053	-1.36650813082738	0.0227900272258748	2
CDH1|E-CADHERIN	0.00184591462562917	0.82781004622601	0.00813022625006199	3
TP53BP1|53BP1	6.72903999117358e-06	0.82285211452904	0.000732195215315827	3
PXN|PAXILLIN	0.000334066104164423	0.71610682502399	0.00291548599998042	3
PRKAA1|AMPK_PT172	0.000975921319491111	0.711914753367424	0.00585940852836527	3
XRCC5|KU80	8.89296058635199e-06	0.67323547902904	0.000732195215315827	3
RPS6|S6	1.80668020493713e-05	0.660293580109849	0.000752817416478907	3
CTNNB2|BETA-CATENIN	0.00314239290081342	0.651941061771465	0.0118301850383564	3
RBM15|RBM15	9.11578499673554e-05	0.624282730862374	0.00129014360793645	3
ATM|ATM	0.00204211814399492	0.622007825907828	0.00852362355754401	3
BCL2L1|BCL-XL	0.000371728310134597	0.620808546751263	0.00297382648107678	3
TSC2|TUBERIN	0.00190552177735828	0.606589147210859	0.00813022625006199	3
EIF4G1|EIF4G	0.00521136463059992	0.560281404064394	0.0173261669930434	3
STAT5A|STAT5-ALPHA	0.0126710702273641	0.551628947907828	0.0338817737751392	3
PTEN|PTEN	0.00124422201406926	0.541394047943182	0.0063242119567106	3
ERBB2|HER2	0.000873825556742973	0.541021927756313	0.00578532782395348	3
RPS6KB1|P70S6K	0.000936502520516314	0.51089611032197	0.00585940852836527	3
EEF2K|EEF2K	0.00131735396407002	0.487178016443182	0.00648543490003702	3
TSC1|TSC1	4.07482501115818e-05	0.474964431897727	0.00076357494187024	3
BRAF|B-RAF	0.00543187006127465	0.454415993342172	0.0176765940977073	3
RAB25|RAB25	0.0206245566802901	0.416544590453283	0.0488878380569839	3
PDK1|PDK1_PS241	0.00015911348560377	0.364555947332071	0.00179704642564258	3
FRAP1|MTOR	0.00190147798737019	0.358583469397727	0.00813022625006199	3
MAP2K1|MEK1	0.0470131656263215	0.35268785002399	0.0960268914920609	3
PRKCD|PKC-DELTA_PS664	0.00219065474333221	0.326458754660354	0.00894905767488903	3
MSH6|MSH6	0.00523394627914853	0.32600075802399	0.0173261669930434	3
DVL3|DVL3	0.00156219946071434	0.305104645968434	0.00731566576724764	3
MAPK14|P38	0.0101301239929193	0.301318075837121	0.0290296090543359	3
GSK3A GSK3B|GSK3-ALPHA-BETA	0.00675170255252006	0.299225749135101	0.0216054481680642	3
ERBB3|HER3	0.0077191244022393	0.286798201710859	0.0239043852456443	3
MAPK9|JNK2	0.00489638305440431	0.259873692741162	0.0167875990436719	3
AKT1 AKT2 AKT3|AKT	0.0183192762110327	0.255040125407828	0.0445227978799782	3
RPTOR|RAPTOR	0.000467495180552876	0.247929264604798	0.00359036298664609	3
NF2|NF2	0.00851978580612435	0.235446906296717	0.025559357418373	3
EIF4EBP1|4E-BP1	0.049584942730018	0.235036302018939	0.100213778991194	3
SMAD1|SMAD1	0.000363291763041753	0.232378870963384	0.00297382648107678	3
PDK1|PDK1	0.00115539129088512	0.228848323069444	0.00616208688472064	3
EGFR|EGFR	0.0189926657414273	0.228480783513889	0.0455823977794255	3
PRKAA1|AMPK_ALPHA	0.00382399098722371	0.228122574448232	0.013690521644769	3
SMAD3|SMAD3	0.00359626861082945	0.227308237584596	0.0132785302553703	3
PIK3R1|PI3K-P85	0.0219379207055585	0.222136038685606	0.0511373392519016	3
EEF2|EEF2	0.00949306295715197	0.205349661619949	0.0278032078192169	3
ERBB2|HER2_PY1248	0.0389819861196629	0.192278153190657	0.0813537101627747	3
XRCC1|XRCC1	0.0458715388799351	0.179361010155303	0.0947025318811563	3
CCNE2|CYCLIN_E2	0.00110936630571601	0.166670495185606	0.00616208688472064	3
CHEK1|CHK1	0.00955735268785582	0.148787999044192	0.0278032078192169	3
ESR1|ER-ALPHA_PS118	0.0127056651656772	0.140310860170454	0.0338817737751392	3
CHEK2|CHK2_PT68	0.0121916791044902	-0.111223288324495	0.0334400341151731	3
PGR|PR	0.00770651174502684	-0.112133672344697	0.0239043852456443	3
RAF1|C-RAF_PS338	0.0119931230935383	-0.126807044880051	0.0333721686081066	3
CDC2|CDK1	0.013501530287219	-0.135119674869949	0.0350309975019736	3
MRE11A|MRE11	0.0136929256339101	-0.148466690875	0.0350538896228099	3
BAK1|BAK	0.0274731000652747	-0.162815938016414	0.0599413092333266	3
YWHAE|14-3-3_EPSILON	1.14405502393098e-05	-0.176618802026515	0.000732195215315827	3
MAPK8|JNK_PT183_PY185	3.28372078205839e-05	-0.179271905228535	0.00076357494187024	3
STMN1|STATHMIN	0.0221062456141033	-0.189767841127525	0.0511373392519016	3
MAP2K1|MEK1_PS217_S221	0.017108118635521	-0.195015244263889	0.0421122920258978	3
PECAM1|CD31	0.0045852184510904	-0.197565739284091	0.0160065807747156	3
NRAS|N-RAS	0.00254861234411599	-0.198069332375	0.0097866714014054	3
YWHAB|14-3-3_BETA	0.00166233697113248	-0.198411012415404	0.00759925472517705	3
TTF1|TTF1	0.000580304767069721	-0.202537359930555	0.00428532751066871	3
PREX1|PREX1	0.0105243019514157	-0.220421415753788	0.0297156760981149	3
JUN|C-JUN_PS73	0.00818216456462417	-0.224433379652778	0.0249361205779022	3
ETS1|ETS-1	3.9577003951464e-05	-0.227426651026515	0.00076357494187024	3
SMAD4|SMAD4	0.001531785134408	-0.237835358930556	0.00731566576724764	3
FOXO3|FOXO3A	0.000309127820075567	-0.247827453728535	0.00282631149783376	3
NFKB1|NF-KB-P65_PS536	0.0362016819968652	-0.250966573814394	0.0763815708065727	3
ARAF|A-RAF_PS299	0.00114493811902611	-0.25332671297601	0.00616208688472064	3
CDH2|N-CADHERIN	0.00236336200059146	-0.255251993385101	0.00945344800236584	3
CASP7|CASPASE-7_CLEAVEDD198	0.0291994247805645	-0.261676443511364	0.0629920175041391	3
TSC2|TUBERIN_PT1462	0.000770196656874249	-0.262570521425505	0.0054769540044391	3
TP53|P53	0.0274000241434456	-0.268487470279041	0.0599413092333266	3
FOXM1|FOXM1	0.00100708584081278	-0.272985076314394	0.00585940852836527	3
SCD1|SCD1	0.000991394564423062	-0.278383685031566	0.00585940852836527	3
EGFR|EGFR_PY1068	0.0259461118794469	-0.283119020137626	0.0579262032657419	3
RB1|RB_PS807_S811	0.0237595793029016	-0.308693759965909	0.0543076098352036	3
ACVRL1|ACVRL1	2.6664769001688e-05	-0.313627966112374	0.000752817416478907	3
SFRS1|SF2	6.35627904360781e-05	-0.315323001531566	0.00101700464697725	3
PRDX1|PRDX1	0.0350811263712343	-0.329158497167929	0.0748397362586332	3
RPS6KA1|P90RSK_PT359_S363	4.37464810446492e-05	-0.335340852127525	0.00076357494187024	3
COPS5|JAB1	0.0134359187972319	-0.346608735420455	0.0350309975019736	3
ARHI|ARHI	0.000802426550818288	-0.347773802319444	0.0055023534913254	3
AKT1 AKT2 AKT3|AKT_PT308	0.000111391116680646	-0.37784942967803	0.00142580629351227	3
ANXA1|ANNEXIN_1	9.40729714120326e-05	-0.419953594981061	0.00129014360793645	3
ESR1|ER-ALPHA	0.00125166694976564	-0.433019614607323	0.0063242119567106	3
AKT1 AKT2 AKT3|AKT_PS473	0.00385045921259129	-0.434185972496212	0.013690521644769	3
SRC|SRC_PY527	0.0241222668867785	-0.464722573960859	0.0544879440266056	3
CCND1|CYCLIN_D1	0.000155483940445996	-0.47606510397601	0.00179704642564258	3
RPS6|S6_PS240_S244	0.0140933100508735	-0.482340995541667	0.0356041517074699	3
RAD51|RAD51	0.000230339783187623	-0.483395722157828	0.00245695768733464	3
RPS6|S6_PS235_S236	0.0146485233484364	-0.546334082809343	0.0365261880896076	3
MAPK14|P38_PT180_Y182	0.00243114545321412	-0.56824453067803	0.00952612095953288	3
SRC|SRC_PY416	0.000259939429672575	-0.582562280228535	0.00262675634195444	3
MAPK1 MAPK3|MAPK_PT202_Y204	2.74464683091268e-05	-0.597056412268939	0.000752817416478907	3
NDRG1|NDRG1_PT346	0.000273977919987381	-0.950302310349747	0.00263018803187886	3
CDKN1A|P21	2.02005639392891e-05	-1.06019489581439	0.000752817416478907	3