Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1q gain 6 (12%) 42 0.28314 0.924 0.68066 1 0.39104 0.95 0.27443 0.924 0.33886 0.926 0.55042 1 0.86114 1 0.31376 0.926 1 1 0.84118 1 2p gain 6 (12%) 42 0.59743 1 0.6834 1 0.34125 0.926 0.82616 1 0.90811 1 1 1 1 1 0.60579 1 0.49805 1 0.24769 0.924 2q gain 6 (12%) 42 0.59402 1 0.68192 1 0.34064 0.926 0.82368 1 0.90775 1 1 1 1 1 0.6041 1 0.49743 1 0.24914 0.924 3p gain 10 (21%) 38 0.02572 0.634 0.61879 1 0.45108 1 0.2479 0.924 0.36661 0.943 0.12737 0.849 0.2033 0.905 0.40276 0.965 0.76083 1 0.70266 1 3q gain 13 (27%) 35 0.00231 0.256 0.3406 0.926 0.23907 0.924 0.0369 0.634 0.065759 0.788 0.01298 0.582 0.22182 0.924 0.56323 1 0.87644 1 0.85855 1 5p gain 7 (15%) 41 0.27914 0.924 0.066959 0.788 0.77422 1 0.68721 1 0.04391 0.634 0.87406 1 1 1 0.63786 1 0.65978 1 0.3163 0.926 5q gain 6 (12%) 42 0.5029 1 0.25573 0.924 0.77237 1 0.68703 1 0.1039 0.821 0.66548 1 1 1 0.80006 1 0.58688 1 0.51115 1 6p gain 6 (12%) 42 0.59755 1 0.86682 1 0.8747 1 0.82596 1 0.36267 0.943 1 1 0.67188 1 0.86108 1 0.91363 1 0.90902 1 6q gain 4 (8%) 44 0.10477 0.821 0.60084 1 0.96041 1 0.76962 1 0.61862 1 0.89495 1 0.44133 1 1 1 0.78032 1 0.32815 0.926 7p gain 14 (29%) 34 0.00251 0.256 0.46455 1 0.81487 1 0.76015 1 0.13293 0.864 0.04117 0.634 0.66521 1 0.69808 1 0.43388 1 0.7347 1 7q gain 12 (25%) 36 0.0035 0.256 0.74868 1 0.82359 1 1 1 0.19849 0.905 0.067759 0.788 0.64925 1 0.91836 1 0.088499 0.793 0.47302 1 8p gain 7 (15%) 41 1 1 0.11696 0.838 0.92061 1 1 1 0.15104 0.875 0.70462 1 0.26439 0.924 0.0055199 0.319 0.37991 0.943 0.14986 0.875 8q gain 8 (17%) 40 0.87491 1 0.04103 0.634 0.77095 1 0.82406 1 0.04855 0.664 0.32354 0.926 0.1362 0.866 0.0276 0.634 0.3763 0.943 0.14846 0.875 9p gain 7 (15%) 41 1 1 0.38662 0.944 0.97534 1 0.43801 1 0.31123 0.926 0.02455 0.634 0.26369 0.924 0.63901 1 0.9116 1 0.29928 0.924 9q gain 7 (15%) 41 0.65235 1 0.38445 0.944 0.97548 1 0.4384 1 0.87359 1 0.089979 0.793 0.26556 0.924 0.29251 0.924 0.85442 1 0.29499 0.924 10p gain 4 (8%) 44 0.10746 0.821 0.89656 1 NA NA NA NA 0.02196 0.634 0.19904 0.905 0.67587 1 1 1 0.77879 1 0.32607 0.926 10q gain 4 (8%) 44 0.10718 0.821 0.59974 1 0.9613 1 0.76823 1 0.18231 0.905 0.19738 0.905 0.44502 1 0.77781 1 0.081729 0.788 0.01248 0.582 11p gain 9 (19%) 39 0.46978 1 0.87182 1 0.2968 0.924 0.37811 0.943 0.20359 0.905 0.51653 1 0.19716 0.905 0.16367 0.902 0.34153 0.926 0.37741 0.943 11q gain 13 (27%) 35 0.82247 1 0.48622 1 0.10049 0.821 0.3588 0.943 0.15346 0.875 0.44257 1 0.91294 1 0.074849 0.788 0.46344 1 0.33902 0.926 12p gain 7 (15%) 41 0.27755 0.924 0.53347 1 0.87416 1 0.2994 0.924 0.76114 1 0.19868 0.905 0.36331 0.943 0.27515 0.924 0.68813 1 0.62324 1 12q gain 9 (19%) 39 0.47395 1 0.23261 0.924 1 1 0.47568 1 0.60696 1 0.30167 0.924 0.19658 0.905 0.13655 0.866 0.26226 0.924 0.14183 0.875 13q gain 5 (10%) 43 0.68732 1 0.78174 1 0.26853 0.924 1 1 0.36644 0.943 0.25676 0.924 0.03473 0.634 0.66108 1 0.19589 0.905 0.57115 1 16p gain 7 (15%) 41 0.65282 1 0.19381 0.905 0.61916 1 1 1 0.083309 0.788 0.077169 0.788 0.46824 1 0.02951 0.634 0.24337 0.924 0.04323 0.634 16q gain 7 (15%) 41 0.55762 1 0.097879 0.821 0.61789 1 1 1 0.33744 0.926 0.31815 0.926 0.46746 1 0.01454 0.582 0.24264 0.924 0.22691 0.924 17q gain 3 (6%) 45 0.7557 1 0.64283 1 0.96042 1 0.76979 1 0.16642 0.902 0.53782 1 0.76263 1 0.03555 0.634 0.78089 1 1 1 18p gain 13 (27%) 35 0.00209 0.256 0.53703 1 0.0037 0.256 0.77913 1 0.49805 1 0.31103 0.926 0.22064 0.924 0.12282 0.849 0.66363 1 0.37083 0.943 18q gain 13 (27%) 35 0.00217 0.256 0.5366 1 0.00394 0.256 0.77838 1 0.49521 1 0.31068 0.926 0.21893 0.924 0.11994 0.843 0.6648 1 0.37152 0.943 19p gain 3 (6%) 45 0.26955 0.924 1 1 NA NA NA NA 0.88065 1 0.63427 1 1 1 0.69042 1 NA NA NA NA 19q gain 3 (6%) 45 0.26853 0.924 1 1 NA NA NA NA 0.88185 1 0.63536 1 1 1 0.69232 1 NA NA NA NA 20p gain 5 (10%) 43 0.83631 1 1 1 0.62972 1 0.15488 0.875 0.072249 0.788 0.43098 1 0.59618 1 0.37823 0.943 0.89806 1 1 1 20q gain 4 (8%) 44 1 1 1 1 0.95981 1 0.11768 0.838 0.22639 0.924 0.51405 1 1 1 0.8183 1 1 1 0.51505 1 21q gain 10 (21%) 38 0.62703 1 0.057469 0.766 0.35311 0.943 0.03401 0.634 0.04519 0.635 0.26671 0.924 0.11054 0.821 0.18263 0.905 0.29591 0.924 0.43097 1 xp gain 6 (12%) 42 0.59437 1 0.68479 1 0.92131 1 0.81591 1 0.90769 1 1 1 0.33554 0.926 0.17745 0.905 0.064829 0.788 0.04204 0.634 xq gain 7 (15%) 41 0.32861 0.926 0.76157 1 0.9208 1 0.81452 1 0.55663 1 0.74686 1 1 1 0.27326 0.924 0.39919 0.961 0.085459 0.793 1p loss 3 (6%) 45 1 1 0.55606 1 0.66282 1 0.56955 1 0.70794 1 1 1 1 1 0.84662 1 NA NA NA NA 3p loss 4 (8%) 44 1 1 1 1 NA NA NA NA 0.29316 0.924 0.71651 1 0.10957 0.821 0.7777 1 0.46213 1 0.37885 0.943 3q loss 3 (6%) 45 0.75643 1 0.64216 1 NA NA NA NA 0.069319 0.788 0.35361 0.943 0.30388 0.924 0.92054 1 NA NA NA NA 4p loss 3 (6%) 45 0.27528 0.924 0.55296 1 NA NA NA NA 0.12905 0.849 0.089069 0.793 0.02811 0.634 0.68734 1 NA NA NA NA 4q loss 4 (8%) 44 0.10636 0.821 0.8952 1 0.66211 1 0.57043 1 0.49231 1 0.89593 1 0.44488 1 0.23543 0.924 0.89648 1 0.573 1 6q loss 7 (15%) 41 0.27799 0.924 0.24034 0.924 0.02215 0.634 1 1 0.8829 1 0.93704 1 0.59771 1 0.72692 1 0.76988 1 0.80384 1 8p loss 8 (17%) 40 0.22407 0.924 1 1 0.14798 0.875 0.04321 0.634 0.51728 1 0.809 1 0.89511 1 0.02585 0.634 1 1 0.65946 1 8q loss 4 (8%) 44 0.10604 0.821 0.73823 1 0.41436 0.988 0.076589 0.788 0.784 1 0.58167 1 0.67462 1 0.15792 0.883 NA NA NA NA 13q loss 3 (6%) 45 0.75654 1 0.46809 1 NA NA NA NA 0.067879 0.788 0.35284 0.943 1 1 0.84813 1 NA NA NA NA 15q loss 7 (15%) 41 0.02642 0.634 0.12868 0.849 0.66109 1 0.57172 1 0.02249 0.634 0.22205 0.924 0.11589 0.838 0.36726 0.943 0.3224 0.926 0.21169 0.924 16q loss 4 (8%) 44 0.10824 0.821 0.24298 0.924 0.17161 0.902 0.56656 1 0.49157 1 0.89542 1 0.20369 0.905 0.12866 0.849 0.17789 0.905 0.082469 0.788 17p loss 9 (19%) 39 0.28497 0.924 0.66391 1 1 1 1 1 0.082519 0.788 0.70292 1 0.73743 1 0.50055 1 0.39864 0.961 0.17401 0.905 17q loss 4 (8%) 44 1 1 0.38076 0.943 NA NA NA NA 0.1835 0.905 0.64669 1 0.4455 1 0.49041 1 0.081869 0.788 0.0376 0.634 18p loss 5 (10%) 43 0.69136 1 0.42827 1 0.96043 1 0.2742 0.924 0.4617 1 0.03533 0.634 0.85926 1 0.24938 0.924 0.20861 0.919 0.38589 0.944 18q loss 5 (10%) 43 0.83735 1 0.42576 1 NA NA NA NA 0.14519 0.875 0.16822 0.902 1 1 0.72768 1 0.19549 0.905 0.1525 0.875 22q loss 3 (6%) 45 0.27079 0.924 0.74212 1 0.29519 0.924 0.76751 1 0.88108 1 1 1 1 1 0.44048 1 NA NA NA NA xp loss 5 (10%) 43 0.54882 1 0.34206 0.926 0.17166 0.902 0.57177 1 0.29659 0.924 0.83926 1 0.59968 1 0.01352 0.582 0.66171 1 0.25533 0.924 xq loss 4 (8%) 44 0.79387 1 0.14562 0.875 0.17088 0.902 0.56966 1 0.079559 0.788 0.45142 1 0.30388 0.924 0.00223 0.256 0.31219 0.926 0.04023 0.634