Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.295 0.244 0.434 33.0 -9999.0 0.0 33.0 KIRREL -0.244 0.277 -9999.0 0.0 -0.549 21.0 21.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.296 0.244 -9999.0 0.0 -0.435 33.0 33.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.216 0.197 -9999.0 0.0 -0.398 22.0 22.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.162 0.168 -9999.0 0.0 -0.327 22.0 22.0 FYN -0.212 0.191 -9999.0 0.0 -0.382 23.0 23.0 mol:Ca2+ -0.214 0.195 -9999.0 0.0 -0.394 22.0 22.0 mol:DAG -0.215 0.196 -9999.0 0.0 -0.396 22.0 22.0 NPHS2 -0.044 0.068 -9999.0 0.0 -0.463 1.0 1.0 mol:IP3 -0.215 0.196 -9999.0 0.0 -0.396 22.0 22.0 regulation of endocytosis -0.193 0.182 -9999.0 0.0 -0.354 23.0 23.0 Nephrin/NEPH1/podocin/Cholesterol -0.224 0.196 -9999.0 0.0 -0.405 22.0 22.0 establishment of cell polarity -0.295 0.244 -9999.0 0.0 -0.434 33.0 33.0 Nephrin/NEPH1/podocin/NCK1-2 -0.19 0.184 -9999.0 0.0 -0.359 22.0 22.0 Nephrin/NEPH1/beta Arrestin2 -0.195 0.185 -9999.0 0.0 -0.358 23.0 23.0 NPHS1 -0.212 0.246 -9999.0 0.0 -0.493 20.0 20.0 Nephrin/NEPH1/podocin -0.213 0.192 -9999.0 0.0 -0.384 23.0 23.0 TJP1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.216 0.197 -9999.0 0.0 -0.398 22.0 22.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.216 0.197 -9999.0 0.0 -0.398 22.0 22.0 GRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.227 0.202 -9999.0 0.0 -0.387 26.0 26.0 cytoskeleton organization -0.194 0.199 -9999.0 0.0 -0.388 22.0 22.0 Nephrin/NEPH1 -0.213 0.183 -9999.0 0.0 -0.383 22.0 22.0 Nephrin/NEPH1/ZO-1 -0.23 0.204 -9999.0 0.0 -0.421 22.0 22.0