Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.097 0.174 0.31 19.0 -9999.0 0.0 19.0 KIRREL -0.116 0.188 -9999.0 0.0 -0.418 13.0 13.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.097 0.175 -9999.0 0.0 -0.31 19.0 19.0 PLCG1 0.03 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.01 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.009 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.05 0.146 -9999.0 0.0 -0.232 18.0 18.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.075 0.119 -9999.0 0.0 -0.224 18.0 18.0 FYN -0.089 0.118 0.193 2.0 -0.218 20.0 22.0 mol:Ca2+ -0.053 0.148 -9999.0 0.0 -0.231 19.0 19.0 mol:DAG -0.053 0.149 -9999.0 0.0 -0.232 19.0 19.0 NPHS2 -0.025 0.037 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.053 0.149 -9999.0 0.0 -0.232 19.0 19.0 regulation of endocytosis -0.06 0.126 -9999.0 0.0 -0.205 20.0 20.0 Nephrin/NEPH1/podocin/Cholesterol -0.06 0.14 -9999.0 0.0 -0.229 19.0 19.0 establishment of cell polarity -0.097 0.174 -9999.0 0.0 -0.31 19.0 19.0 Nephrin/NEPH1/podocin/NCK1-2 -0.04 0.145 -9999.0 0.0 -0.214 19.0 19.0 Nephrin/NEPH1/beta Arrestin2 -0.06 0.128 -9999.0 0.0 -0.207 20.0 20.0 NPHS1 -0.084 0.148 -9999.0 0.0 -0.392 8.0 8.0 Nephrin/NEPH1/podocin -0.063 0.133 -9999.0 0.0 -0.219 20.0 20.0 TJP1 0.028 0.008 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.03 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.052 0.151 -9999.0 0.0 -0.233 19.0 19.0 CD2AP 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.052 0.151 -9999.0 0.0 -0.233 19.0 19.0 GRB2 0.03 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.081 0.126 0.216 2.0 -0.223 18.0 20.0 cytoskeleton organization -0.099 0.128 -9999.0 0.0 -0.26 18.0 18.0 Nephrin/NEPH1 -0.062 0.123 -9999.0 0.0 -0.212 19.0 19.0 Nephrin/NEPH1/ZO-1 -0.069 0.146 -9999.0 0.0 -0.245 19.0 19.0