Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.032 0.133 0.587 10.0 -9999.0 0.0 10.0 KIRREL 0.01 0.013 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.032 0.133 -9999.0 0.0 -0.588 10.0 10.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.024 0.099 -9999.0 0.0 -0.436 10.0 10.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.017 0.062 -9999.0 0.0 -9999.0 0.0 0.0 FYN -0.001 0.093 -9999.0 0.0 -0.391 10.0 10.0 mol:Ca2+ -0.024 0.098 -9999.0 0.0 -0.432 10.0 10.0 mol:DAG -0.024 0.098 -9999.0 0.0 -0.434 10.0 10.0 NPHS2 0.004 0.015 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.024 0.098 -9999.0 0.0 -0.434 10.0 10.0 regulation of endocytosis -0.02 0.082 -9999.0 0.0 -0.362 10.0 10.0 Nephrin/NEPH1/podocin/Cholesterol -0.024 0.101 -9999.0 0.0 -0.444 10.0 10.0 establishment of cell polarity -0.032 0.133 -9999.0 0.0 -0.587 10.0 10.0 Nephrin/NEPH1/podocin/NCK1-2 -0.021 0.09 -9999.0 0.0 -0.395 10.0 10.0 Nephrin/NEPH1/beta Arrestin2 -0.02 0.083 -9999.0 0.0 -0.367 10.0 10.0 NPHS1 -0.033 0.178 -9999.0 0.0 -0.775 10.0 10.0 Nephrin/NEPH1/podocin -0.021 0.089 -9999.0 0.0 -0.393 10.0 10.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.024 0.099 -9999.0 0.0 -0.436 10.0 10.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.024 0.099 -9999.0 0.0 -0.436 10.0 10.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 0.002 0.097 -9999.0 0.0 -0.401 10.0 10.0 cytoskeleton organization 0.021 0.081 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1 -0.024 0.099 -9999.0 0.0 -0.436 10.0 10.0 Nephrin/NEPH1/ZO-1 -0.026 0.108 -9999.0 0.0 -0.477 10.0 10.0