Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.027 0.022 0.283 2.0 -9999.0 0.0 2.0 KIRREL 0.018 0.02 -9999.0 0.0 -0.41 1.0 1.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.027 0.022 -9999.0 0.0 -0.283 2.0 2.0 PLCG1 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.019 0.078 -9999.0 0.0 -0.216 51.0 51.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.029 0.021 -9999.0 0.0 -0.121 4.0 4.0 FYN 0.019 0.017 -9999.0 0.0 -0.173 4.0 4.0 mol:Ca2+ 0.043 0.023 -9999.0 0.0 -0.191 2.0 2.0 mol:DAG 0.044 0.024 -9999.0 0.0 -0.192 2.0 2.0 NPHS2 0.019 0.006 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.044 0.024 -9999.0 0.0 -0.192 2.0 2.0 regulation of endocytosis 0.037 0.019 -9999.0 0.0 -0.158 4.0 4.0 Nephrin/NEPH1/podocin/Cholesterol 0.034 0.024 -9999.0 0.0 -0.197 2.0 2.0 establishment of cell polarity 0.027 0.022 -9999.0 0.0 -0.283 2.0 2.0 Nephrin/NEPH1/podocin/NCK1-2 0.047 0.037 -9999.0 0.0 -0.173 13.0 13.0 Nephrin/NEPH1/beta Arrestin2 0.039 0.019 -9999.0 0.0 -0.159 4.0 4.0 NPHS1 0.018 0.02 -9999.0 0.0 -0.41 1.0 1.0 Nephrin/NEPH1/podocin 0.032 0.019 -9999.0 0.0 -0.173 4.0 4.0 TJP1 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.008 0.061 -9999.0 0.0 -0.413 11.0 11.0 NCK2 0.017 0.001 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.045 0.024 -9999.0 0.0 -0.193 2.0 2.0 CD2AP -0.023 0.125 -9999.0 0.0 -0.413 49.0 49.0 Nephrin/NEPH1/podocin/GRB2 0.044 0.023 -9999.0 0.0 -0.193 2.0 2.0 GRB2 0.017 0.002 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 0.022 0.023 -9999.0 0.0 -0.193 5.0 5.0 cytoskeleton organization 0.031 0.023 0.168 4.0 -0.149 2.0 6.0 Nephrin/NEPH1 0.023 0.016 -9999.0 0.0 -0.191 2.0 2.0 Nephrin/NEPH1/ZO-1 0.036 0.018 -9999.0 0.0 -0.216 2.0 2.0