Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.02 0.106 -9999.0 0.0 -0.426 12.0 12.0 MAP3K8 0.02 0.016 0.125 12.0 -0.019 6.0 18.0 FOS -0.028 0.101 -9999.0 0.0 -0.439 12.0 12.0 PRKCA 0.02 0.006 -9999.0 0.0 -0.025 7.0 7.0 PTPN7 0.036 0.037 0.125 96.0 -0.031 7.0 103.0 HRAS 0.02 0.005 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.014 0.011 -9999.0 0.0 -0.025 7.0 7.0 NRAS 0.019 0.007 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.033 0.017 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.006 0.073 -9999.0 0.0 -0.488 6.0 6.0 MAP2K1 -0.065 0.136 -9999.0 0.0 -0.291 169.0 169.0 ELK1 0.021 0.006 -9999.0 0.0 -0.034 7.0 7.0 BRAF -0.045 0.115 -9999.0 0.0 -0.285 121.0 121.0 mol:GTP -0.0 0.0 -9999.0 0.0 -0.004 7.0 7.0 MAPK1 -0.012 0.094 -9999.0 0.0 -0.504 14.0 14.0 RAF1 -0.074 0.135 -9999.0 0.0 -0.284 190.0 190.0 KRAS 0.02 0.004 -9999.0 0.0 -9999.0 0.0 0.0