Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q amp_2q11.2 107 (20%) 415 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.04159 0.0821 0.54304 0.642 0.085019 0.149 9.9999e-06 4.94e-05 0.00064999 0.00215 0.00067999 0.00223 0.70079 0.771 0.73594 0.792 amp_2q31.2 112 (21%) 410 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.16347 0.259 0.31186 0.423 0.04124 0.0816 9.9999e-06 4.94e-05 0.00442 0.0118 0.0066699 0.0168 0.25653 0.358 0.55725 0.654 amp_3q26.33 380 (73%) 142 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.080939 0.144 0.30871 0.422 9.9999e-06 4.94e-05 0.00023 0.000821 0.00056999 0.00191 0.59359 0.685 0.20011 0.302 0.22708 0.33 amp_5p15.33 240 (46%) 282 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.51667 0.617 0.82962 0.868 0.0050599 0.0133 0.68681 0.764 0.69469 0.769 0.03374 0.0689 0.57261 0.665 0.63602 0.725 amp_5p12 205 (39%) 317 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.17891 0.276 0.14645 0.238 0.050209 0.0959 0.23416 0.338 0.4361 0.548 0.01619 0.0367 0.69815 0.77 0.71288 0.778 amp_6p12.1 110 (21%) 412 9.9999e-06 4.94e-05 2e-05 8.94e-05 0.49931 0.6 0.95059 0.957 0.11168 0.189 0.03722 0.0756 0.56207 0.658 0.0023 0.00675 0.40234 0.512 0.2368 0.339 amp_6q12 96 (18%) 426 9.9999e-06 4.94e-05 7.9999e-05 0.000315 0.68945 0.766 0.8999 0.919 0.089049 0.155 0.0061199 0.0156 0.18278 0.281 0.23439 0.338 0.84184 0.876 0.54712 0.645 amp_7p11.2 222 (43%) 300 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.85443 0.887 0.6714 0.754 0.02382 0.0513 9.9999e-06 4.94e-05 0.00022 0.000789 9.9999e-06 4.94e-05 0.22617 0.329 0.21871 0.323 amp_7q21.3 169 (32%) 353 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.76541 0.818 0.44217 0.552 0.01281 0.0297 9.9999e-06 4.94e-05 0.082749 0.147 0.00015 0.000562 0.24198 0.343 0.93517 0.945 amp_8p11.23 161 (31%) 361 9.9999e-06 4.94e-05 0.03855 0.0774 0.94865 0.957 0.87389 0.899 0.24132 0.343 0.16954 0.266 0.066429 0.123 0.01092 0.0258 0.40438 0.514 0.04529 0.0883 amp_8q11.21 310 (59%) 212 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.02241 0.0489 0.63451 0.724 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.00222 0.00656 0.0052199 0.0136 0.093399 0.161 0.00434 0.0117 amp_8q24.21 386 (74%) 136 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.0059899 0.0153 0.4474 0.555 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.00109 0.00345 0.00268 0.00766 0.00089999 0.00286 amp_9p24.1 126 (24%) 396 9.9999e-06 4.94e-05 2e-05 8.94e-05 0.13441 0.22 0.25119 0.352 0.00074999 0.00243 0.01429 0.0326 0.00385 0.0105 0.00129 0.004 0.26299 0.364 0.32579 0.438 amp_9p23 124 (24%) 398 9.9999e-06 4.94e-05 0.00014 0.000527 0.38698 0.496 0.42478 0.536 0.00136 0.0042 0.01946 0.0435 0.00163 0.00492 0.00218 0.00647 0.33135 0.442 0.53353 0.634 amp_9p13.3 139 (27%) 383 9.9999e-06 4.94e-05 0.00389 0.0106 0.2473 0.348 0.12217 0.203 0.00027 0.000954 0.00144 0.0044 0.22626 0.329 0.059529 0.111 0.75824 0.812 0.4543 0.561 amp_9q34.3 177 (34%) 345 9.9999e-06 4.94e-05 0.00012 0.000456 0.65218 0.738 0.02368 0.0511 0.37974 0.492 0.00446 0.0118 0.22528 0.329 0.086219 0.151 0.96022 0.965 0.96824 0.972 amp_11p13 102 (20%) 420 0.00223 0.00657 0.00049 0.00166 0.17301 0.269 0.17675 0.274 0.083919 0.148 0.56542 0.661 0.63193 0.722 0.49246 0.593 0.90479 0.922 0.04218 0.083 amp_11q13.3 229 (44%) 293 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.79671 0.841 0.73273 0.79 9.9999e-06 4.94e-05 0.03181 0.0655 0.0301 0.0626 0.0046 0.0121 0.38106 0.492 0.2008 0.303 amp_12p13.33 167 (32%) 355 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.25052 0.352 0.52351 0.624 0.00177 0.0053 8.9999e-05 0.000349 0.02595 0.0552 0.087489 0.152 0.67224 0.754 0.77106 0.822 amp_12q15 103 (20%) 419 2e-05 8.94e-05 6.9999e-05 0.000277 0.30273 0.415 0.20515 0.309 0.10244 0.175 0.00167 0.00502 0.87981 0.904 0.32227 0.434 0.3965 0.506 0.73655 0.792 amp_13q22.1 105 (20%) 417 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.38443 0.494 0.15669 0.251 0.64968 0.737 0.076439 0.139 0.33202 0.442 0.16216 0.258 0.46077 0.565 0.61942 0.712 amp_13q34 106 (20%) 416 9.9999e-06 4.94e-05 0.00047 0.00159 0.779 0.828 0.49175 0.593 0.24358 0.344 0.00402 0.0109 0.12396 0.205 0.1327 0.217 0.46583 0.568 0.31047 0.423 amp_15q26.3 105 (20%) 417 3e-05 0.000129 0.00443 0.0118 0.69916 0.77 0.32747 0.439 0.22448 0.329 0.075659 0.138 0.54862 0.645 0.050979 0.0969 0.52871 0.629 0.079409 0.143 amp_17q12 91 (17%) 431 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.69776 0.77 0.72177 0.787 0.00255 0.00737 3e-05 0.000129 0.02066 0.0458 4e-05 0.000168 0.70482 0.773 0.22393 0.329 amp_18p11.31 156 (30%) 366 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.21122 0.316 0.51637 0.617 0.0094599 0.0228 9.9999e-06 4.94e-05 0.01064 0.0253 2e-04 0.000724 0.94975 0.957 0.22211 0.327 amp_18q11.2 106 (20%) 416 2e-05 8.94e-05 0.00033 0.00116 0.77332 0.823 0.20733 0.311 0.10725 0.182 0.01261 0.0293 0.0079899 0.0196 0.02871 0.0603 0.79831 0.841 0.6806 0.76 amp_20q11.22 227 (43%) 295 9.9999e-06 4.94e-05 3e-05 0.000129 0.04875 0.0938 0.832 0.87 0.058689 0.11 0.0287 0.0603 0.91026 0.924 0.02359 0.0511 0.57902 0.672 0.01728 0.039 amp_xq28 150 (29%) 372 9.9999e-06 4.94e-05 9.9999e-05 0.000382 0.74485 0.8 0.19638 0.297 0.25698 0.358 0.31545 0.427 0.56765 0.662 0.094609 0.163 0.69385 0.769 0.60541 0.697 del_1p36.21 95 (18%) 427 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.02097 0.0463 0.0057799 0.015 6.9999e-05 0.000277 9.9999e-06 4.94e-05 0.0070899 0.0176 0.04046 0.0807 0.00355 0.00992 0.0068099 0.017 del_1p13.2 133 (25%) 389 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.0108 0.0256 0.0071199 0.0176 0.15612 0.251 2e-05 8.94e-05 0.00080999 0.0026 9.9999e-05 0.000382 0.076929 0.14 0.62835 0.72 del_1q44 48 (9%) 474 8.9999e-05 0.000349 0.01197 0.0281 0.79993 0.842 0.90962 0.924 0.0085299 0.0207 0.01019 0.0244 0.00037 0.00128 0.04593 0.0891 0.24209 0.343 0.48596 0.587 del_2q21.2 78 (15%) 444 0.04953 0.0949 0.055109 0.104 0.5037 0.605 0.2125 0.317 0.0062999 0.016 2e-04 0.000724 0.03862 0.0774 0.25863 0.36 0.31097 0.423 0.1708 0.267 del_2q22.1 121 (23%) 401 0.00468 0.0123 9.9999e-05 0.000382 0.38745 0.496 0.83742 0.873 0.12307 0.204 0.0097199 0.0233 0.081059 0.144 0.00139 0.00428 0.88965 0.912 0.57154 0.665 del_2q36.2 157 (30%) 365 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.18613 0.285 0.85947 0.89 0.0087999 0.0213 0.065909 0.122 0.069589 0.128 0.02482 0.053 0.10281 0.176 0.090079 0.156 del_3p26.2 348 (67%) 174 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.17848 0.276 0.21096 0.316 5e-05 0.000203 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.053379 0.101 0.01981 0.0442 del_3p24.1 368 (70%) 154 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.22353 0.329 0.11279 0.19 0.00126 0.00394 9.9999e-06 4.94e-05 5.9999e-05 0.000241 5e-05 0.000203 0.01425 0.0326 0.11075 0.188 del_3p14.2 372 (71%) 150 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.35921 0.471 0.17542 0.272 0.0057899 0.015 9.9999e-06 4.94e-05 0.00144 0.0044 0.00041 0.00141 0.03187 0.0655 0.21445 0.318 del_3p12.1 343 (66%) 179 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.6691 0.753 0.90232 0.92 0.00161 0.00487 9.9999e-06 4.94e-05 0.00014 0.000527 0.00047 0.00159 0.080789 0.144 0.48184 0.585 del_4p16.3 205 (39%) 317 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.19553 0.297 0.40812 0.518 0.00246 0.00716 9.9999e-06 4.94e-05 0.064139 0.119 0.069459 0.128 0.0081399 0.0199 0.04124 0.0816 del_4p15.2 208 (40%) 314 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.02482 0.053 0.33589 0.446 0.0056899 0.0148 9.9999e-06 4.94e-05 0.0064599 0.0163 0.03017 0.0626 0.00111 0.00349 0.00296 0.00839 del_4q21.3 156 (30%) 366 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.73186 0.79 0.04648 0.0899 0.1461 0.238 2e-05 8.94e-05 0.25909 0.36 0.03149 0.065 0.44301 0.552 0.02964 0.0619 del_4q22.1 169 (32%) 353 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.47742 0.581 0.074499 0.136 0.12006 0.201 0.00024 0.000852 0.44336 0.552 0.03998 0.08 0.44613 0.554 0.087069 0.152 del_4q35.2 213 (41%) 309 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.87081 0.897 0.18602 0.285 0.080659 0.144 0.00017 0.000633 0.23538 0.339 0.0060099 0.0153 0.14668 0.238 0.16422 0.26 del_5q12.1 215 (41%) 307 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.00419 0.0113 0.36127 0.471 0.073549 0.135 9.9999e-06 4.94e-05 0.00264 0.0076 3e-05 0.000129 0.35137 0.461 0.52257 0.623 del_5q15 226 (43%) 296 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.01881 0.0422 0.43138 0.544 0.31128 0.423 9.9999e-06 4.94e-05 0.01211 0.0283 2e-05 8.94e-05 0.65147 0.738 0.78016 0.828 del_5q35.3 199 (38%) 323 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.12091 0.202 0.72262 0.787 0.0070199 0.0174 9.9999e-06 4.94e-05 0.03774 0.0763 4e-05 0.000168 0.36065 0.471 0.22916 0.332 del_6p25.3 96 (18%) 426 0.0058199 0.015 9.9999e-06 4.94e-05 0.29788 0.409 0.01068 0.0254 0.0036 0.00999 0.17242 0.269 0.0373 0.0756 0.72553 0.789 0.681 0.76 0.67209 0.754 del_7q31.1 77 (15%) 445 0.00018 0.000667 0.3419 0.452 0.72985 0.79 0.38057 0.492 0.00364 0.0101 0.54847 0.645 0.00217 0.00647 0.17569 0.272 0.18672 0.285 0.39764 0.507 del_7q36.1 132 (25%) 390 2e-05 8.94e-05 0.32675 0.439 0.31418 0.426 0.67377 0.754 0.04289 0.084 0.80524 0.846 0.0071799 0.0177 0.33132 0.442 0.51662 0.617 0.29042 0.399 del_8p23.2 305 (58%) 217 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.12222 0.203 0.32171 0.434 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.00316 0.00889 0.02647 0.0562 5e-05 0.000203 del_9p23 239 (46%) 283 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.12429 0.205 0.11334 0.191 0.00051999 0.00175 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 8.9999e-05 0.000349 0.48475 0.587 0.97871 0.98 del_9p21.3 302 (58%) 220 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.15151 0.244 0.36077 0.471 4e-05 0.000168 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.27663 0.382 0.03644 0.0742 del_9q21.11 108 (21%) 414 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.70289 0.772 0.23736 0.339 0.074499 0.136 0.02284 0.0497 0.00234 0.00684 0.00060999 0.00203 0.4442 0.553 0.12188 0.203 del_9q34.3 79 (15%) 443 9.9999e-06 4.94e-05 2e-04 0.000724 0.8283 0.868 0.3693 0.48 0.43419 0.546 0.44223 0.552 0.78816 0.834 0.0095799 0.023 0.45245 0.56 0.25952 0.36 del_10p15.3 170 (33%) 352 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.75725 0.812 0.70868 0.776 0.00079999 0.00258 0.003 0.00848 0.00021 0.000756 0.080279 0.144 0.02764 0.0585 0.68628 0.764 del_10p11.21 163 (31%) 359 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.54914 0.645 0.21982 0.324 5.9999e-05 0.000241 0.02214 0.0485 2e-05 8.94e-05 0.01111 0.0261 0.03859 0.0774 0.86044 0.89 del_10q23.31 138 (26%) 384 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.23738 0.339 0.97987 0.98 0.00047 0.00159 0.00281 0.008 0.00035 0.00122 0.46207 0.565 0.32969 0.441 0.45581 0.561 del_11p15.5 163 (31%) 359 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.7688 0.821 0.2821 0.388 0.00083999 0.00268 0.01375 0.0317 2e-05 8.94e-05 0.0038 0.0104 0.33555 0.446 0.01417 0.0325 del_11q23.1 246 (47%) 276 2e-05 8.94e-05 9.9999e-06 4.94e-05 0.34261 0.452 0.16571 0.261 2e-05 8.94e-05 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.01318 0.0304 0.04459 0.0871 0.15968 0.255 del_12q24.33 63 (12%) 459 9.9999e-06 4.94e-05 2e-04 0.000724 0.84345 0.877 0.45568 0.561 0.3503 0.461 0.1045 0.178 0.35146 0.461 0.12096 0.202 0.43823 0.55 0.73245 0.79 del_13q12.11 233 (45%) 289 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.16174 0.258 0.24035 0.342 0.078719 0.142 2e-05 8.94e-05 0.01993 0.0443 0.03082 0.0638 0.62951 0.721 0.83749 0.873 del_13q14.2 217 (42%) 305 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.21416 0.318 0.56637 0.661 3e-05 0.000129 6.9999e-05 0.000277 0.0011 0.00347 0.21623 0.32 0.91037 0.924 0.02142 0.0472 del_14q11.2 75 (14%) 447 0.00365 0.0101 0.0067199 0.0169 0.17053 0.267 0.89829 0.919 0.24057 0.342 0.14941 0.242 0.00447 0.0118 0.03259 0.0668 0.38725 0.496 0.65388 0.738 del_14q32.32 75 (14%) 447 0.00129 0.004 9.9999e-06 4.94e-05 0.053489 0.101 0.46587 0.568 2e-05 8.94e-05 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.0289 0.0605 0.38187 0.492 0.11151 0.189 del_15q15.1 124 (24%) 398 9.9999e-06 4.94e-05 0.050399 0.096 0.64976 0.737 0.4143 0.525 0.02481 0.053 0.063539 0.119 0.73042 0.79 0.63965 0.728 0.48177 0.585 0.93292 0.944 del_16q23.1 98 (19%) 424 0.00037 0.00128 9.9999e-06 4.94e-05 0.78855 0.834 0.45531 0.561 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.04083 0.0812 0.27328 0.378 0.00064999 0.00215 del_16q23.3 105 (20%) 417 0.00065999 0.00217 9.9999e-06 4.94e-05 0.42047 0.532 0.23306 0.337 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 5e-05 0.000203 0.16522 0.261 0.37935 0.492 0.02181 0.0479 del_17p11.2 99 (19%) 423 9.9999e-06 4.94e-05 0.00147 0.00447 0.85813 0.89 0.97319 0.976 0.19324 0.294 0.10013 0.172 0.1403 0.229 0.12564 0.207 0.86686 0.894 0.93273 0.944 del_17q25.3 71 (14%) 451 0.01442 0.0328 2e-05 8.94e-05 0.10014 0.172 0.6905 0.766 0.00266 0.00763 0.083119 0.147 0.00357 0.00994 0.04958 0.0949 0.02804 0.0592 0.0059699 0.0153 del_18q23 288 (55%) 234 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.18124 0.279 0.2461 0.347 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 2e-05 8.94e-05 9.9999e-06 4.94e-05 0.082389 0.146 0.01689 0.0382 del_19p13.3 175 (34%) 347 9.9999e-06 4.94e-05 3e-05 0.000129 0.54224 0.642 0.36574 0.476 0.00072999 0.00237 0.00068999 0.00225 0.04665 0.09 2e-04 0.000724 0.53588 0.635 0.2523 0.353 del_19q13.43 97 (19%) 425 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.21359 0.318 0.5872 0.678 0.33819 0.448 5e-05 0.000203 0.04271 0.0839 0.065809 0.122 0.16545 0.261 0.57993 0.672 del_21q22.3 208 (40%) 314 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.65562 0.739 0.72672 0.789 0.04594 0.0891 9.9999e-06 4.94e-05 0.00028 0.000985 5e-05 0.000203 0.084219 0.148 0.18954 0.289 del_xp22.2 157 (30%) 365 9.9999e-06 4.94e-05 9.9999e-06 4.94e-05 0.62173 0.714 0.00247 0.00716 0.4836 0.586 0.01735 0.039 0.0085199 0.0207 0.15804 0.253 0.86656 0.894 0.89149 0.913 del_xp21.3 159 (30%) 363 9.9999e-06 4.94e-05 4e-05 0.000168 0.78669 0.834 0.055239 0.104 0.80992 0.85 0.02326 0.0505 0.15209 0.245 0.084839 0.149 0.71194 0.778 0.45712 0.561 del_xq21.33 80 (15%) 442 3e-05 0.000129 9.9999e-06 4.94e-05 0.5852 0.677 0.12815 0.21 0.00345 0.00968 0.00383 0.0105 0.0068299 0.017 0.01235 0.0288 0.23646 0.339 0.077759 0.141