Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.062 0.186 0.59 54.0 -9999.0 0.0 54.0 KIRREL -0.022 0.138 -9999.0 0.0 -0.628 25.0 25.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.062 0.187 -9999.0 0.0 -0.592 54.0 54.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.057 0.171 -9999.0 0.0 -0.562 43.0 43.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.009 0.121 -9999.0 0.0 -0.596 10.0 10.0 FYN -0.036 0.164 -9999.0 0.0 -0.511 44.0 44.0 mol:Ca2+ -0.056 0.168 -9999.0 0.0 -0.555 43.0 43.0 mol:DAG -0.056 0.169 -9999.0 0.0 -0.559 43.0 43.0 NPHS2 -0.024 0.133 -9999.0 0.0 -0.843 13.0 13.0 mol:IP3 -0.056 0.169 -9999.0 0.0 -0.559 43.0 43.0 regulation of endocytosis -0.049 0.147 -9999.0 0.0 -0.749 11.0 11.0 Nephrin/NEPH1/podocin/Cholesterol -0.058 0.173 -9999.0 0.0 -0.571 43.0 43.0 establishment of cell polarity -0.062 0.186 -9999.0 0.0 -0.59 54.0 54.0 Nephrin/NEPH1/podocin/NCK1-2 -0.052 0.157 -9999.0 0.0 -0.842 10.0 10.0 Nephrin/NEPH1/beta Arrestin2 -0.026 0.158 -9999.0 0.0 -0.766 11.0 11.0 NPHS1 -0.048 0.202 -9999.0 0.0 -0.823 33.0 33.0 Nephrin/NEPH1/podocin -0.051 0.16 -9999.0 0.0 -0.515 44.0 44.0 TJP1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.057 0.171 -9999.0 0.0 -0.562 43.0 43.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.057 0.171 -9999.0 0.0 -0.562 43.0 43.0 GRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.055 0.196 -9999.0 0.0 -0.53 65.0 65.0 cytoskeleton organization -0.013 0.154 -9999.0 0.0 -0.77 10.0 10.0 Nephrin/NEPH1 -0.047 0.141 -9999.0 0.0 -0.442 54.0 54.0 Nephrin/NEPH1/ZO-1 -0.051 0.153 -9999.0 0.0 -0.551 37.0 37.0