Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.442 0.215 0.531 55.0 -9999.0 0.0 55.0 KIRREL -0.092 0.139 -9999.0 0.0 -0.699 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.443 0.215 -9999.0 0.0 -0.532 55.0 55.0 PLCG1 0.022 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.029 0.026 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.021 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.441 0.26 -9999.0 0.0 -0.517 57.0 57.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.388 0.231 -9999.0 0.0 -0.465 54.0 54.0 FYN -0.422 0.232 -9999.0 0.0 -0.487 57.0 57.0 mol:Ca2+ -0.435 0.257 -9999.0 0.0 -0.515 56.0 56.0 mol:DAG -0.437 0.259 -9999.0 0.0 -0.518 56.0 56.0 NPHS2 -0.298 0.311 -9999.0 0.0 -0.696 25.0 25.0 mol:IP3 -0.437 0.259 -9999.0 0.0 -0.518 56.0 56.0 regulation of endocytosis -0.392 0.235 -9999.0 0.0 -0.46 57.0 57.0 Nephrin/NEPH1/podocin/Cholesterol -0.441 0.255 -9999.0 0.0 -0.515 57.0 57.0 establishment of cell polarity -0.442 0.215 -9999.0 0.0 -0.531 55.0 55.0 Nephrin/NEPH1/podocin/NCK1-2 -0.413 0.249 -9999.0 0.0 -0.486 57.0 57.0 Nephrin/NEPH1/beta Arrestin2 -0.398 0.24 -9999.0 0.0 -0.467 57.0 57.0 NPHS1 -0.55 0.25 -9999.0 0.0 -0.667 54.0 54.0 Nephrin/NEPH1/podocin -0.42 0.245 -9999.0 0.0 -0.49 57.0 57.0 TJP1 0.022 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.022 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.023 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.44 0.261 -9999.0 0.0 -0.521 56.0 56.0 CD2AP 0.021 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.441 0.26 -9999.0 0.0 -0.517 57.0 57.0 GRB2 0.021 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.41 0.233 -9999.0 0.0 -0.484 55.0 55.0 cytoskeleton organization -0.485 0.267 -9999.0 0.0 -0.576 54.0 54.0 Nephrin/NEPH1 -0.324 0.163 -9999.0 0.0 -0.389 55.0 55.0 Nephrin/NEPH1/ZO-1 -0.363 0.187 -9999.0 0.0 -0.44 55.0 55.0