Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.559 0.333 0.742 663.0 -9999.0 0.0 663.0 KIRREL -0.092 0.199 -9999.0 0.0 -0.924 47.0 47.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.56 0.334 -9999.0 0.0 -0.744 663.0 663.0 PLCG1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.044 -9999.0 0.0 -0.737 3.0 3.0 WASL 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.613 0.384 -9999.0 0.0 -0.762 715.0 715.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.454 0.298 -9999.0 0.0 -0.767 353.0 353.0 FYN -0.576 0.37 -9999.0 0.0 -0.721 715.0 715.0 mol:Ca2+ -0.602 0.375 -9999.0 0.0 -0.749 715.0 715.0 mol:DAG -0.607 0.379 -9999.0 0.0 -0.755 715.0 715.0 NPHS2 -0.429 0.435 -9999.0 0.0 -0.925 385.0 385.0 mol:IP3 -0.607 0.379 -9999.0 0.0 -0.755 715.0 715.0 regulation of endocytosis -0.544 0.342 -9999.0 0.0 -0.681 699.0 699.0 Nephrin/NEPH1/podocin/Cholesterol -0.621 0.387 -9999.0 0.0 -0.772 715.0 715.0 establishment of cell polarity -0.559 0.333 -9999.0 0.0 -0.742 663.0 663.0 Nephrin/NEPH1/podocin/NCK1-2 -0.569 0.363 -9999.0 0.0 -0.945 364.0 364.0 Nephrin/NEPH1/beta Arrestin2 -0.556 0.353 -9999.0 0.0 -0.696 699.0 699.0 NPHS1 -0.661 0.394 -9999.0 0.0 -0.9 649.0 649.0 Nephrin/NEPH1/podocin -0.586 0.369 -9999.0 0.0 -0.729 715.0 715.0 TJP1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.613 0.384 -9999.0 0.0 -0.762 715.0 715.0 CD2AP 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.613 0.384 -9999.0 0.0 -0.762 715.0 715.0 GRB2 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.626 0.392 -9999.0 0.0 -0.759 739.0 739.0 cytoskeleton organization -0.602 0.386 -9999.0 0.0 -0.757 702.0 702.0 Nephrin/NEPH1 -0.431 0.264 -9999.0 0.0 -0.573 663.0 663.0 Nephrin/NEPH1/ZO-1 -0.465 0.285 -9999.0 0.0 -0.619 663.0 663.0