Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.402 0.256 0.548 647.0 -9999.0 0.0 647.0 KIRREL -0.081 0.146 -9999.0 0.0 -0.662 46.0 46.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.403 0.257 -9999.0 0.0 -0.549 647.0 647.0 PLCG1 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.024 0.03 -9999.0 0.0 -0.457 3.0 3.0 WASL 0.025 0.01 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.418 0.292 -9999.0 0.0 -0.544 692.0 692.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.347 0.246 -9999.0 0.0 -0.467 647.0 647.0 FYN -0.404 0.263 0.262 1.0 -0.515 693.0 694.0 mol:Ca2+ -0.409 0.288 -9999.0 0.0 -0.541 674.0 674.0 mol:DAG -0.411 0.29 -9999.0 0.0 -0.544 674.0 674.0 NPHS2 -0.319 0.329 -9999.0 0.0 -0.697 374.0 374.0 mol:IP3 -0.411 0.29 -9999.0 0.0 -0.544 674.0 674.0 regulation of endocytosis -0.37 0.258 -9999.0 0.0 -0.491 659.0 659.0 Nephrin/NEPH1/podocin/Cholesterol -0.424 0.288 -9999.0 0.0 -0.546 695.0 695.0 establishment of cell polarity -0.402 0.256 -9999.0 0.0 -0.548 647.0 647.0 Nephrin/NEPH1/podocin/NCK1-2 -0.383 0.28 -9999.0 0.0 -0.508 681.0 681.0 Nephrin/NEPH1/beta Arrestin2 -0.375 0.264 -9999.0 0.0 -0.499 659.0 659.0 NPHS1 -0.499 0.306 -9999.0 0.0 -0.686 638.0 638.0 Nephrin/NEPH1/podocin -0.401 0.275 -9999.0 0.0 -0.518 693.0 693.0 TJP1 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.413 0.292 -9999.0 0.0 -0.548 674.0 674.0 CD2AP 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.412 0.29 -9999.0 0.0 -0.545 673.0 673.0 GRB2 0.025 0.009 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.437 0.281 0.273 1.0 -0.541 711.0 712.0 cytoskeleton organization -0.429 0.3 -9999.0 0.0 -0.583 635.0 635.0 Nephrin/NEPH1 -0.295 0.194 -9999.0 0.0 -0.406 642.0 642.0 Nephrin/NEPH1/ZO-1 -0.325 0.221 -9999.0 0.0 -0.452 641.0 641.0