Clinical Features	Time to Death		YEARS_TO_BIRTH		GENDER		RADIATION_THERAPY		KARNOFSKY_PERFORMANCE_SCORE		HISTOLOGICAL_TYPE		RACE		ETHNICITY	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
IDH1	400 (78%)	115	0	0	9.815e-09	1.2e-06	1	1	0.012282	0.289	0.002855	0.0914	0.0055499	0.151	0.02504	0.439	1	1
TP53	250 (49%)	265	0.044415	0.597	3.0722e-12	7.54e-10	0.24989	0.9	0.00018236	0.0079	0.36603	0.921	9.9999e-06	0.000613	0.03217	0.526	0.71519	1
ATRX	197 (38%)	318	0.081349	0.682	2.7134e-12	7.54e-10	0.78446	1	0.012271	0.289	0.93928	1	9.9999e-06	0.000613	0.3959	0.936	1	1
CIC	108 (21%)	407	8.1629e-05	0.00429	0.10939	0.737	0.32771	0.921	6.8186e-06	0.000613	0.23605	0.9	9.9999e-06	0.000613	0.74773	1	0.65539	1
NOTCH1	42 (8%)	473	0.2098	0.863	0.042953	0.596	0.74698	1	0.50401	1	0.87882	1	5e-05	0.00283	0.33423	0.921	1	1
IDH2	20 (4%)	495	0.059711	0.668	0.073887	0.668	1	1	0.47429	0.992	0.61726	1	0.00092999	0.036	0.44962	0.982	0.12505	0.761
PIK3R1	22 (4%)	493	0.35992	0.921	0.080598	0.682	0.27478	0.916	0.37041	0.921	0.75386	1	0.35278	0.921	0.04464	0.597	0.62272	1
FUBP1	47 (9%)	468	0.13261	0.787	0.0030458	0.0934	0.64473	1	0.072816	0.668	0.23403	0.9	9.9999e-06	0.000613	1	1	0.099792	0.718
NF1	33 (6%)	482	9.5894e-05	0.00471	0.01256	0.289	0.59001	1	0.56817	1	0.55542	1	0.01577	0.324	0.21874	0.875	0.25684	0.9
TCF12	15 (3%)	500	0.61047	1	0.22736	0.9	0.60074	1	1	1	0.90925	1	0.89408	1	1	1	0.6133	1
PTEN	24 (5%)	491	0.00012669	0.00583	0.0017563	0.0646	0.29714	0.916	0.068364	0.668	0.59153	1	0.00276	0.0914	0.16347	0.803	1	1
ARID1A	20 (4%)	495	0.036341	0.566	0.64656	1	0.49282	1	0.34902	0.921	0.95816	1	0.19628	0.836	1	1	1	1
EGFR	35 (7%)	480	1.876e-11	3.45e-09	4.9238e-11	7.25e-09	1	1	0.022701	0.414	0.0053541	0.151	0.050319	0.65	0.17763	0.808	0.71702	1
GAGE2A	8 (2%)	507	0.51781	1	0.73417	1	0.73692	1	1	1	0.32821	0.921	1	1	0.054049	0.667	0.4259	0.95
NUDT11	11 (2%)	504	0.47484	0.992	0.32246	0.921	0.36003	0.921	1	1	0.63936	1	0.73988	1	1	1	1	1
PIK3CA	44 (9%)	471	0.64763	1	0.073255	0.668	0.87518	1	0.19763	0.836	0.10634	0.737	0.01764	0.342	0.62942	1	0.7413	1
STK19	10 (2%)	505	0.30141	0.916	0.31054	0.916	0.11932	0.75	0.68056	1	0.23291	0.9	0.074249	0.668	1	1	0.13814	0.802
SMARCA4	26 (5%)	489	0.0051558	0.151	0.52494	1	0.31842	0.921	1	1	0.43142	0.956	0.81636	1	0.11437	0.746	0.64263	1
NIPBL	18 (3%)	497	0.055992	0.668	0.17526	0.808	0.15657	0.803	0.30993	0.916	0.60121	1	0.069139	0.668	0.074439	0.668	0.11017	0.737
TRERF1	6 (1%)	509	0.25805	0.9	0.28261	0.916	0.09384	0.691	0.68056	1	0.80099	1	0.16823	0.803	1	1	1	1
CREBZF	7 (1%)	508	0.96508	1	0.1707	0.803	0.25099	0.9	1	1	0.07261	0.668	0.03115	0.521	0.35379	0.921	0.38433	0.921
DNMT3A	11 (2%)	504	0.033317	0.533	0.66641	1	1	1	0.54216	1	0.94612	1	0.20843	0.862	0.49469	1	0.53493	1
EMG1	5 (1%)	510	0.53459	1	0.083944	0.682	0.17776	0.808	1	1	0.14213	0.803	0.85072	1	1	1	1	1
IRS4	8 (2%)	507	0.13899	0.802	0.8874	1	1	1	1	1	0.24241	0.9	0.091959	0.685	1	1	0.4259	0.95
MYST4	11 (2%)	504	0.16262	0.803	0.10889	0.737	1	1	1	1	0.92462	1	0.19025	0.836	0.1467	0.803	0.50103	1
MED9	3 (1%)	512	0.30482	0.916	0.86836	1	0.25711	0.9	0.28758	0.916	NA	NA	0.01586	0.324	1	1	1	1
FAM47C	19 (4%)	496	0.068666	0.668	0.70377	1	0.24984	0.9	0.46089	0.986	0.63175	1	0.76259	1	1	1	1	1
NRAS	4 (1%)	511	0.43026	0.956	0.88527	1	1	1	0.64168	1	0.47071	0.99	0.02234	0.414	1	1	1	1
PLXNA3	9 (2%)	506	0.070075	0.668	0.24945	0.9	0.19744	0.836	0.16019	0.803	0.58966	1	0.83427	1	0.10522	0.737	1	1
TNRC18	10 (2%)	505	0.36093	0.921	0.7421	1	0.19705	0.836	0.32956	0.921	0.41714	0.939	0.36638	0.921	1	1	1	1
HTRA2	5 (1%)	510	0.34441	0.921	0.027671	0.474	1	1	0.38589	0.921	NA	NA	0.45241	0.982	1	1	0.29228	0.916
ZMIZ1	9 (2%)	506	0.069292	0.668	0.858	1	0.52172	1	1	1	0.14987	0.803	0.43598	0.964	0.065309	0.668	0.017113	0.34
CUL4B	10 (2%)	505	0.16836	0.803	0.82217	1	0.11932	0.75	0.16314	0.803	0.63936	1	0.33509	0.921	0.21835	0.875	1	1
DLX6	4 (1%)	511	0.31237	0.916	0.97573	1	0.63211	1	1	1	NA	NA	0.4574	0.982	1	1	1	1
RB1	6 (1%)	509	0.83448	1	0.16418	0.803	0.41473	0.936	1	1	NA	NA	0.096479	0.703	0.30751	0.916	1	1
ROBO3	5 (1%)	510	0.36452	0.921	0.53097	1	0.66043	1	0.64168	1	0.66936	1	0.37967	0.921	1	1	0.29228	0.916
SRPX	4 (1%)	511	0.19875	0.836	0.042867	0.596	0.039207	0.566	1	1	0.55424	1	0.37443	0.921	0.22017	0.876	1	1
RBPJ	7 (1%)	508	0.86872	1	0.053926	0.667	1	1	0.68056	1	0.33814	0.921	0.27421	0.916	1	1	1	1
TMEM216	3 (1%)	512	0.74063	1	0.81651	1	0.088432	0.682	1	1	NA	NA	0.36777	0.921	1	1	1	1
ARID2	11 (2%)	504	0.50222	1	0.10844	0.737	1	1	0.21654	0.875	0.80253	1	0.20843	0.862	0.24477	0.9	1	1
SLC6A3	9 (2%)	506	0.60482	1	0.37768	0.921	0.52172	1	1	1	NA	NA	0.75892	1	1	1	0.38433	0.921
PDGFRA	10 (2%)	505	0.15609	0.803	0.70663	1	0.35349	0.921	0.74758	1	0.14562	0.803	0.11492	0.746	1	1	0.13814	0.802
PTPN11	7 (1%)	508	0.28796	0.916	0.34166	0.921	1	1	1	1	0.75313	1	0.30708	0.916	0.35139	0.921	1	1
MYT1	6 (1%)	509	0.26283	0.9	0.40827	0.936	1	1	0.086543	0.682	0.73308	1	0.16555	0.803	1	1	1	1
ZNF292	14 (3%)	501	0.98511	1	0.0065429	0.172	0.17436	0.808	0.57563	1	0.62493	1	0.88889	1	0.13955	0.802	0.59616	1
PPL	6 (1%)	509	0.038257	0.566	0.72541	1	1	1	1	1	0.80099	1	0.45776	0.982	1	1	0.29228	0.916
CIB1	4 (1%)	511	0.4076	0.936	1	1	1	1	1	1	0.75313	1	1	1	1	1	1	1
ANKRD36	7 (1%)	508	0.092106	0.685	0.59041	1	0.70563	1	0.046897	0.616	0.071076	0.668	0.2348	0.9	0.069339	0.668	1	1
NAP1L2	4 (1%)	511	0.26299	0.9	0.17738	0.808	1	1	0.64168	1	NA	NA	0.19107	0.836	1	1	1	1
SMOC1	3 (1%)	512	0.33831	0.921	0.44349	0.974	1	1	0.28758	0.916	0.47071	0.99	0.47602	0.992	1	1	1	1
ABCA7	10 (2%)	505	0.92543	1	0.3108	0.916	0.52349	1	1	1	0.63917	1	0.60967	1	1	1	0.50103	1
ZNF512B	5 (1%)	510	0.078216	0.682	0.2992	0.916	1	1	1	1	NA	NA	1	1	1	1	0.29228	0.916
PRX	10 (2%)	505	0.77092	1	0.46199	0.986	0.35349	0.921	0.32956	0.921	0.3282	0.921	0.77962	1	1	1	0.50103	1
SMARCB1	4 (1%)	511	0.305	0.916	0.809	1	0.63211	1	0.30348	0.916	0.75313	1	1	1	1	1	1	1
C9ORF79	10 (2%)	505	0.11141	0.739	0.27498	0.916	1	1	0.16019	0.803	0.16875	0.803	0.56604	1	0.45785	0.982	1	1
KRT3	4 (1%)	511	0.089941	0.682	0.85647	1	0.63211	1	1	1	0.10662	0.737	0.68218	1	1	1	0.24139	0.9
ELF4	4 (1%)	511	0.087876	0.682	0.81556	1	0.039207	0.566	0.64168	1	NA	NA	0.68272	1	1	1	1	1
NEU2	6 (1%)	509	0.52622	1	0.30747	0.916	1	1	1	1	NA	NA	0.45695	0.982	1	1	0.33986	0.921
ZNF709	3 (1%)	512	0.50341	1	0.60807	1	0.25711	0.9	1	1	NA	NA	0.36714	0.921	0.16907	0.803	1	1
R3HDM1	7 (1%)	508	0.05756	0.668	0.87071	1	1	1	1	1	0.75313	1	0.49127	1	1	1	0.38433	0.921
PLCG1	6 (1%)	509	1.0752e-07	1.13e-05	0.014714	0.319	0.41473	0.936	0.41309	0.936	0.31105	0.916	0.29895	0.916	0.3103	0.916	1	1
C14ORF4	3 (1%)	512	0.46616	0.989	0.74175	1	0.58873	1	1	1	NA	NA	0.78704	1	0.16739	0.803	1	1
ZBTB20	21 (4%)	494	0.41072	0.936	0.49758	1	0.37164	0.921	0.15878	0.803	0.80424	1	0.18318	0.817	0.12706	0.767	0.63511	1
C4BPA	6 (1%)	509	0.52106	1	0.64219	1	0.41473	0.936	0.41309	0.936	0.17124	0.803	0.88758	1	0.30885	0.916	0.33986	0.921
ENGASE	5 (1%)	510	0.50646	1	0.88568	1	0.66043	1	0.16178	0.803	0.99054	1	0.26184	0.9	1	1	1	1
DLC1	6 (1%)	509	0.54663	1	0.54932	1	0.41473	0.936	0.086543	0.682	NA	NA	0.66225	1	1	1	0.33986	0.921
G6PC	6 (1%)	509	0.86609	1	0.40047	0.936	0.69638	1	0.41309	0.936	0.51379	1	0.45577	0.982	1	1	0.054397	0.667
SLC12A7	7 (1%)	508	0.23824	0.9	0.53846	1	0.70563	1	0.41309	0.936	0.51854	1	1	1	0.35201	0.921	1	1
RET	7 (1%)	508	0.64524	1	0.50026	1	0.25099	0.9	0.43753	0.964	0.60172	1	0.071259	0.668	1	1	1	1
SETD2	10 (2%)	505	0.55936	1	0.007978	0.202	1	1	0.74758	1	0.31143	0.916	0.36718	0.921	0.46422	0.987	1	1
ZC3H11A	6 (1%)	509	0.61295	1	0.19507	0.836	0.69638	1	1	1	0.33751	0.921	0.66503	1	1	1	1	1
USP6	7 (1%)	508	0.084626	0.682	0.52167	1	1	1	0.25758	0.9	0.072496	0.668	0.30621	0.916	0.35123	0.921	1	1
RBBP6	6 (1%)	509	0.19379	0.836	0.32144	0.921	1	1	0.68056	1	NA	NA	0.77372	1	0.12437	0.761	1	1
SLFN11	6 (1%)	509	0.089493	0.682	0.058341	0.668	0.69638	1	1	1	0.47071	0.99	0.34977	0.921	1	1	0.33986	0.921
ASXL2	3 (1%)	512	0.11797	0.75	0.41281	0.936	0.58873	1	1	1	NA	NA	0.6283	1	1	1	1	1
KRT15	6 (1%)	509	0.74968	1	0.11556	0.746	0.69638	1	0.21141	0.864	0.41168	0.936	0.88788	1	0.30886	0.916	1	1
FMR1	5 (1%)	510	0.068669	0.668	0.18146	0.817	1	1	0.6533	1	0.356	0.921	0.12514	0.761	1	1	1	1
DDX5	5 (1%)	510	0.33056	0.921	0.85352	1	1	1	1	1	0.29237	0.916	0.85246	1	1	1	0.24139	0.9
SCN4A	6 (1%)	509	0.18245	0.817	0.26032	0.9	0.41473	0.936	0.68056	1	0.33964	0.921	0.77394	1	1	1	1	1
CCDC135	7 (1%)	508	0.23332	0.9	0.75549	1	0.25099	0.9	1	1	NA	NA	0.70508	1	1	1	0.38433	0.921
MYOCD	9 (2%)	506	0.14639	0.803	0.41035	0.936	1	1	0.16314	0.803	0.50273	1	0.01431	0.319	0.42595	0.95	1	1
TMEM184A	3 (1%)	512	0.00046949	0.0192	0.15181	0.803	1	1	1	1	NA	NA	1	1	0.16521	0.803	1	1
KTELC1	5 (1%)	510	0.30806	0.916	0.66075	1	0.38685	0.921	0.6533	1	NA	NA	0.84897	1	1	1	1	1
GPR133	4 (1%)	511	0.27104	0.916	0.51362	1	1	1	1	1	NA	NA	1	1	1	1	0.24139	0.9
CDH3	3 (1%)	512	0.29444	0.916	0.6273	1	0.088432	0.682	1	1	NA	NA	0.63247	1	1	1	1	1
SLC25A5	4 (1%)	511	0.023064	0.414	0.57698	1	0.32901	0.921	1	1	0.25481	0.9	0.83965	1	0.21792	0.875	1	1
LAMA4	4 (1%)	511	0.79245	1	0.35536	0.921	0.13211	0.787	1	1	0.75313	1	0.066609	0.668	0.078509	0.682	0.24139	0.9
NKD2	4 (1%)	511	0.968	1	0.68871	1	1	1	0.16237	0.803	NA	NA	0.45734	0.982	1	1	1	1
WRN	5 (1%)	510	0.083599	0.682	0.37844	0.921	0.66043	1	1	1	0.03874	0.566	0.54912	1	0.26423	0.9	0.0024518	0.0859
PHF3	8 (2%)	507	0.69322	1	0.60839	1	1	1	0.16019	0.803	0.12021	0.75	0.60562	1	0.3866	0.921	0.38433	0.921
AGBL1	5 (1%)	510	0.24129	0.9	0.20473	0.856	0.38685	0.921	1	1	NA	NA	0.18957	0.836	1	1	1	1
ZNF148	4 (1%)	511	0.10053	0.718	0.66768	1	1	1	0.16237	0.803	NA	NA	0.37842	0.921	0.079739	0.682	1	1