Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.063 0.149 0.4 81.0 -9999.0 0.0 81.0 KIRREL -0.037 0.164 -9999.0 0.0 -0.594 41.0 41.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.063 0.15 -9999.0 0.0 -0.4 81.0 81.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.046 0.108 -9999.0 0.0 -0.337 42.0 42.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.004 0.096 -9999.0 0.0 -0.338 13.0 13.0 FYN -0.024 0.109 -9999.0 0.0 -0.321 42.0 42.0 mol:Ca2+ -0.045 0.108 -9999.0 0.0 -0.334 42.0 42.0 mol:DAG -0.045 0.108 -9999.0 0.0 -0.335 42.0 42.0 NPHS2 -0.006 0.039 -9999.0 0.0 -0.537 2.0 2.0 mol:IP3 -0.045 0.108 -9999.0 0.0 -0.335 42.0 42.0 regulation of endocytosis -0.015 0.103 -9999.0 0.0 -0.495 4.0 4.0 Nephrin/NEPH1/podocin/Cholesterol -0.047 0.112 -9999.0 0.0 -0.346 42.0 42.0 establishment of cell polarity -0.063 0.149 -9999.0 0.0 -0.4 81.0 81.0 Nephrin/NEPH1/podocin/NCK1-2 -0.041 0.099 -9999.0 0.0 -0.533 5.0 5.0 Nephrin/NEPH1/beta Arrestin2 -0.014 0.104 -9999.0 0.0 -0.502 4.0 4.0 NPHS1 -0.035 0.141 -9999.0 0.0 -0.494 44.0 44.0 Nephrin/NEPH1/podocin -0.027 0.109 -9999.0 0.0 -0.323 42.0 42.0 TJP1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.027 -9999.0 0.0 -0.593 1.0 1.0 NCK2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.046 0.108 -9999.0 0.0 -0.337 42.0 42.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.046 0.109 -9999.0 0.0 -0.337 42.0 42.0 GRB2 0.013 0.022 -9999.0 0.0 -0.489 1.0 1.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.043 0.134 -9999.0 0.0 -0.337 55.0 55.0 cytoskeleton organization -0.004 0.111 -9999.0 0.0 -0.388 13.0 13.0 Nephrin/NEPH1 -0.045 0.107 -9999.0 0.0 -0.333 41.0 41.0 Nephrin/NEPH1/ZO-1 -0.049 0.117 -9999.0 0.0 -0.365 41.0 41.0