Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.087	0.284	0.508	78.0	-0.63	21.0	99.0
IHH	0.054	0.158	0.337	29.0	-0.595	10.0	39.0
SHH Np/Cholesterol/GAS1	-0.053	0.155	0.211	1.0	-0.393	54.0	55.0
LRPAP1	0.025	0.005	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.053	0.154	0.391	54.0	-0.209	1.0	55.0
SMO/beta Arrestin2	0.046	0.23	0.379	22.0	-0.613	28.0	50.0
SMO	0.033	0.244	0.396	29.0	-0.661	27.0	56.0
AKT1	0.035	0.173	0.305	9.0	-0.471	19.0	28.0
ARRB2	0.022	0.01	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.036	0.054	0.339	11.0	-9999.0	0.0	11.0
ADRBK1	0.025	0.004	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	0.034	0.239	0.395	29.0	-0.646	27.0	56.0
STIL	0.074	0.21	0.421	37.0	-0.526	20.0	57.0
DHH N/PTCH2	0.035	0.042	0.247	3.0	-0.46	2.0	5.0
DHH N/PTCH1	0.057	0.212	0.391	28.0	-0.532	28.0	56.0
PIK3CA	0.024	0.034	-9999.0	0.0	-0.616	1.0	1.0
DHH	0.026	0.017	0.339	1.0	-9999.0	0.0	1.0
PTHLH	0.098	0.312	0.582	72.0	-0.673	21.0	93.0
determination of left/right symmetry	0.034	0.239	0.395	29.0	-0.646	27.0	56.0
PIK3R1	0.022	0.048	-9999.0	0.0	-0.616	2.0	2.0
skeletal system development	0.098	0.31	0.581	72.0	-0.666	21.0	93.0
IHH N/Hhip	-0.2	0.278	0.308	1.0	-0.491	167.0	168.0
DHH N/Hhip	-0.189	0.245	-9999.0	0.0	-0.461	161.0	161.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	0.034	0.239	0.395	29.0	-0.646	27.0	56.0
pancreas development	-0.265	0.314	0.338	1.0	-0.603	167.0	168.0
HHAT	0.019	0.035	-9999.0	0.0	-0.616	1.0	1.0
PI3K	0.034	0.052	-9999.0	0.0	-0.642	2.0	2.0
EntrezGene:84976	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.093	0.25	0.339	1.0	-0.607	69.0	70.0
somite specification	0.034	0.239	0.395	29.0	-0.646	27.0	56.0
SHH Np/Cholesterol/PTCH1	0.02	0.189	0.379	12.0	-0.479	30.0	42.0
SHH Np/Cholesterol/PTCH2	0.006	0.077	0.207	2.0	-0.391	11.0	13.0
SHH Np/Cholesterol/Megalin	-0.027	0.154	0.23	24.0	-0.372	50.0	74.0
SHH	-0.004	0.09	0.254	2.0	-0.492	11.0	13.0
catabolic process	0.06	0.245	0.397	70.0	-0.581	28.0	98.0
SMO/Vitamin D3	0.064	0.241	0.444	28.0	-0.591	26.0	54.0
SHH Np/Cholesterol/Hhip	-0.146	0.185	-9999.0	0.0	-0.374	130.0	130.0
LRP2	-0.043	0.24	0.339	24.0	-0.609	50.0	74.0
receptor-mediated endocytosis	0.007	0.245	0.39	25.0	-0.554	35.0	60.0
SHH Np/Cholesterol/BOC	0.012	0.081	0.221	10.0	-0.381	11.0	21.0
SHH Np/Cholesterol/CDO	0.006	0.074	-9999.0	0.0	-0.39	11.0	11.0
mesenchymal cell differentiation	0.145	0.183	0.372	130.0	-9999.0	0.0	130.0
mol:Vitamin D3	0.073	0.223	0.455	27.0	-0.48	30.0	57.0
IHH N/PTCH2	0.046	0.109	0.265	7.0	-0.419	11.0	18.0
CDON	0.025	0.005	-9999.0	0.0	-9999.0	0.0	0.0
IHH N/PTCH1	0.076	0.255	0.425	72.0	-0.586	28.0	100.0
Megalin/LRPAP1	-0.018	0.182	0.247	23.0	-0.454	50.0	73.0
PTCH2	0.023	0.053	0.339	2.0	-0.616	2.0	4.0
SHH Np/Cholesterol	-0.001	0.072	-9999.0	0.0	-0.357	13.0	13.0
PTCH1	0.06	0.246	0.397	70.0	-0.584	28.0	98.0
HHIP	-0.266	0.315	0.339	1.0	-0.604	167.0	168.0