Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.133 0.209 0.401 29.0 -9999.0 0.0 29.0 KIRREL -0.054 0.166 -9999.0 0.0 -0.533 9.0 9.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.133 0.209 -9999.0 0.0 -0.402 29.0 29.0 PLCG1 0.029 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.084 0.173 -9999.0 0.0 -0.312 28.0 28.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.082 0.157 -9999.0 0.0 -0.3 25.0 25.0 FYN -0.088 0.171 0.27 4.0 -0.296 29.0 33.0 mol:Ca2+ -0.086 0.172 -9999.0 0.0 -0.308 29.0 29.0 mol:DAG -0.086 0.173 -9999.0 0.0 -0.309 29.0 29.0 NPHS2 -0.022 0.057 -9999.0 0.0 -0.281 2.0 2.0 mol:IP3 -0.086 0.173 -9999.0 0.0 -0.309 29.0 29.0 regulation of endocytosis -0.079 0.158 -9999.0 0.0 -0.287 27.0 27.0 Nephrin/NEPH1/podocin/Cholesterol -0.094 0.167 -9999.0 0.0 -0.309 29.0 29.0 establishment of cell polarity -0.133 0.209 -9999.0 0.0 -0.401 29.0 29.0 Nephrin/NEPH1/podocin/NCK1-2 -0.073 0.177 -9999.0 0.0 -0.299 27.0 27.0 Nephrin/NEPH1/beta Arrestin2 -0.079 0.161 -9999.0 0.0 -0.291 27.0 27.0 NPHS1 -0.159 0.232 -9999.0 0.0 -0.42 36.0 36.0 Nephrin/NEPH1/podocin -0.09 0.162 -9999.0 0.0 -0.298 29.0 29.0 TJP1 0.021 0.057 -9999.0 0.0 -0.503 1.0 1.0 NCK1 0.029 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.022 0.057 -9999.0 0.0 -0.503 1.0 1.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.086 0.175 -9999.0 0.0 -0.31 29.0 29.0 CD2AP 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.089 0.172 -9999.0 0.0 -0.31 29.0 29.0 GRB2 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.099 0.177 0.279 4.0 -0.302 30.0 34.0 cytoskeleton organization -0.104 0.187 0.204 4.0 -0.361 25.0 29.0 Nephrin/NEPH1 -0.09 0.152 -9999.0 0.0 -0.296 27.0 27.0 Nephrin/NEPH1/ZO-1 -0.1 0.187 -9999.0 0.0 -0.345 27.0 27.0