Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.019 0.194 -9999.0 0.0 -0.625 20.0 20.0 MAP3K8 0.01 0.024 -9999.0 0.0 -0.408 1.0 1.0 FOS -0.017 0.17 -9999.0 0.0 -0.696 13.0 13.0 PRKCA -0.002 0.09 -9999.0 0.0 -0.533 8.0 8.0 PTPN7 -0.014 0.126 -9999.0 0.0 -0.6 13.0 13.0 HRAS 0.012 0.001 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.042 0.175 -9999.0 0.0 -0.59 27.0 27.0 NRAS 0.011 0.024 -9999.0 0.0 -0.408 1.0 1.0 RAS family/GTP 0.014 0.043 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.011 0.143 -9999.0 0.0 -0.667 11.0 11.0 MAP2K1 -0.013 0.138 -9999.0 0.0 -0.465 24.0 24.0 ELK1 0.01 0.026 -9999.0 0.0 -0.441 1.0 1.0 BRAF -0.019 0.136 -9999.0 0.0 -0.467 24.0 24.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.004 28.0 28.0 MAPK1 -0.013 0.145 -9999.0 0.0 -0.682 11.0 11.0 RAF1 -0.019 0.136 -9999.0 0.0 -0.467 24.0 24.0 KRAS -0.002 0.075 -9999.0 0.0 -0.41 10.0 10.0