Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.001 0.099 0.351 20.0 -9999.0 0.0 20.0 KIRREL 0.024 0.025 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.001 0.099 -9999.0 0.0 -0.351 20.0 20.0 PLCG1 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.03 0.083 -9999.0 0.0 -0.271 18.0 18.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.001 0.069 -9999.0 0.0 -0.259 18.0 18.0 FYN -0.002 0.086 0.178 11.0 -0.251 21.0 32.0 mol:Ca2+ 0.028 0.083 -9999.0 0.0 -0.271 19.0 19.0 mol:DAG 0.029 0.084 -9999.0 0.0 -0.272 19.0 19.0 NPHS2 0.012 0.028 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.029 0.084 -9999.0 0.0 -0.272 19.0 19.0 regulation of endocytosis 0.026 0.076 -9999.0 0.0 -0.24 20.0 20.0 Nephrin/NEPH1/podocin/Cholesterol 0.016 0.078 -9999.0 0.0 -0.27 19.0 19.0 establishment of cell polarity -0.001 0.099 -9999.0 0.0 -0.351 20.0 20.0 Nephrin/NEPH1/podocin/NCK1-2 0.043 0.082 -9999.0 0.0 -0.251 18.0 18.0 Nephrin/NEPH1/beta Arrestin2 0.027 0.077 -9999.0 0.0 -0.242 20.0 20.0 NPHS1 -0.023 0.132 -9999.0 0.0 -0.492 21.0 21.0 Nephrin/NEPH1/podocin 0.017 0.077 -9999.0 0.0 -0.252 21.0 21.0 TJP1 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.029 0.085 -9999.0 0.0 -0.273 19.0 19.0 CD2AP 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.03 0.084 -9999.0 0.0 -0.272 19.0 19.0 GRB2 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.016 0.094 0.16 30.0 -0.265 24.0 54.0 cytoskeleton organization -0.014 0.085 0.202 3.0 -0.32 19.0 22.0 Nephrin/NEPH1 0.009 0.07 -9999.0 0.0 -0.253 19.0 19.0 Nephrin/NEPH1/ZO-1 0.021 0.085 -9999.0 0.0 -0.29 19.0 19.0