Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.004 0.117 -9999.0 0.0 -0.389 17.0 17.0 MAP3K8 0.023 0.023 0.06 26.0 -0.037 62.0 88.0 FOS 0.026 0.128 0.445 26.0 -0.378 11.0 37.0 PRKCA 0.023 0.027 0.098 23.0 -0.042 60.0 83.0 PTPN7 0.023 0.038 0.152 25.0 -0.043 85.0 110.0 HRAS 0.022 0.021 0.051 1.0 -0.023 88.0 89.0 PRKCB 0.001 0.015 0.068 26.0 -0.022 1.0 27.0 NRAS 0.012 0.017 -9999.0 0.0 -0.032 20.0 20.0 RAS family/GTP 0.023 0.043 0.173 23.0 -9999.0 0.0 23.0 MAPK3 0.027 0.113 0.319 25.0 -0.424 20.0 45.0 MAP2K1 0.029 0.076 0.264 26.0 -0.284 7.0 33.0 ELK1 0.022 0.028 0.069 26.0 -0.052 61.0 87.0 BRAF 0.02 0.046 0.183 22.0 -0.242 3.0 25.0 mol:GTP -0.0 0.003 0.012 26.0 -0.005 63.0 89.0 MAPK1 0.019 0.122 0.319 25.0 -0.397 29.0 54.0 RAF1 0.021 0.051 0.186 22.0 -0.348 3.0 25.0 KRAS 0.019 0.02 -9999.0 0.0 -0.011 147.0 147.0