Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.049 0.138 0.359 29.0 -9999.0 0.0 29.0 KIRREL -0.076 0.199 -9999.0 0.0 -0.529 29.0 29.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.049 0.138 -9999.0 0.0 -0.36 29.0 29.0 PLCG1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.028 0.103 -9999.0 0.0 -0.259 29.0 29.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.017 0.1 -9999.0 0.0 -0.255 22.0 22.0 FYN -0.021 0.104 -9999.0 0.0 -0.248 29.0 29.0 mol:Ca2+ -0.028 0.102 -9999.0 0.0 -0.257 29.0 29.0 mol:DAG -0.028 0.103 -9999.0 0.0 -0.258 29.0 29.0 NPHS2 -0.003 0.02 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.028 0.103 -9999.0 0.0 -0.258 29.0 29.0 regulation of endocytosis -0.023 0.093 -9999.0 0.0 -0.236 27.0 27.0 Nephrin/NEPH1/podocin/Cholesterol -0.033 0.102 -9999.0 0.0 -0.262 29.0 29.0 establishment of cell polarity -0.049 0.138 -9999.0 0.0 -0.359 29.0 29.0 Nephrin/NEPH1/podocin/NCK1-2 -0.02 0.095 -9999.0 0.0 -0.255 22.0 22.0 Nephrin/NEPH1/beta Arrestin2 -0.023 0.094 -9999.0 0.0 -0.238 27.0 27.0 NPHS1 0.001 0.018 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin -0.03 0.098 -9999.0 0.0 -0.249 29.0 29.0 TJP1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.028 0.103 -9999.0 0.0 -0.259 29.0 29.0 CD2AP 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.028 0.103 -9999.0 0.0 -0.259 29.0 29.0 GRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.019 0.1 -9999.0 0.0 -0.257 22.0 22.0 cytoskeleton organization -0.019 0.112 -9999.0 0.0 -0.285 22.0 22.0 Nephrin/NEPH1 -0.032 0.097 -9999.0 0.0 -0.25 29.0 29.0 Nephrin/NEPH1/ZO-1 -0.032 0.111 -9999.0 0.0 -0.282 29.0 29.0