Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.257 0.243 -9999.0 0.0 -0.428 99.0 99.0 MAP3K8 0.019 0.055 -9999.0 0.0 -0.381 3.0 3.0 FOS -0.265 0.23 -9999.0 0.0 -0.43 99.0 99.0 PRKCA 0.017 0.056 -9999.0 0.0 -0.384 3.0 3.0 PTPN7 -0.225 0.197 -9999.0 0.0 -0.382 99.0 99.0 HRAS 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.023 0.035 -9999.0 0.0 -0.397 1.0 1.0 NRAS 0.024 0.01 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.043 0.023 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.262 0.217 -9999.0 0.0 -0.408 107.0 107.0 MAP2K1 0.007 0.074 0.222 1.0 -0.34 5.0 6.0 ELK1 0.026 0.012 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.008 0.055 -9999.0 0.0 -0.319 4.0 4.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.005 4.0 4.0 MAPK1 -0.278 0.238 -9999.0 0.0 -0.43 108.0 108.0 RAF1 0.006 0.063 -9999.0 0.0 -0.302 6.0 6.0 KRAS 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0