Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.067 0.152 0.346 112.0 -9999.0 0.0 112.0 KIRREL -0.087 0.196 -9999.0 0.0 -0.472 102.0 102.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.067 0.152 -9999.0 0.0 -0.347 112.0 112.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.039 0.115 -9999.0 0.0 -0.321 16.0 16.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.029 0.105 -9999.0 0.0 -0.356 5.0 5.0 FYN -0.042 0.11 -9999.0 0.0 -0.309 16.0 16.0 mol:Ca2+ -0.04 0.114 -9999.0 0.0 -0.319 16.0 16.0 mol:DAG -0.039 0.115 -9999.0 0.0 -0.32 16.0 16.0 NPHS2 -0.011 0.049 -9999.0 0.0 -0.584 3.0 3.0 mol:IP3 -0.039 0.115 -9999.0 0.0 -0.32 16.0 16.0 regulation of endocytosis -0.031 0.104 -9999.0 0.0 -0.442 4.0 4.0 Nephrin/NEPH1/podocin/Cholesterol -0.048 0.115 -9999.0 0.0 -0.255 112.0 112.0 establishment of cell polarity -0.067 0.152 -9999.0 0.0 -0.346 112.0 112.0 Nephrin/NEPH1/podocin/NCK1-2 -0.028 0.108 -9999.0 0.0 -0.409 5.0 5.0 Nephrin/NEPH1/beta Arrestin2 -0.031 0.106 -9999.0 0.0 -0.448 4.0 4.0 NPHS1 -0.015 0.086 -9999.0 0.0 -0.572 11.0 11.0 Nephrin/NEPH1/podocin -0.042 0.11 -9999.0 0.0 -0.31 16.0 16.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.026 -9999.0 0.0 -0.573 1.0 1.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.039 0.115 -9999.0 0.0 -0.321 16.0 16.0 CD2AP 0.013 0.001 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.039 0.115 -9999.0 0.0 -0.324 15.0 15.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.079 0.158 -9999.0 0.0 -0.419 57.0 57.0 cytoskeleton organization -0.029 0.115 -9999.0 0.0 -0.392 5.0 5.0 Nephrin/NEPH1 -0.045 0.106 -9999.0 0.0 -0.24 112.0 112.0 Nephrin/NEPH1/ZO-1 -0.043 0.121 -9999.0 0.0 -0.334 14.0 14.0