Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.009 0.105 0.225 91.0 -0.188 1.0 92.0 KIRREL -0.036 0.134 -9999.0 0.0 -0.315 91.0 91.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.009 0.106 0.189 1.0 -0.225 91.0 92.0 PLCG1 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.008 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.025 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.021 0.095 0.226 1.0 -0.168 90.0 91.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.015 0.078 -9999.0 0.0 -0.187 80.0 80.0 FYN -0.028 0.068 0.215 12.0 -0.165 72.0 84.0 mol:Ca2+ 0.019 0.092 0.218 1.0 -0.166 89.0 90.0 mol:DAG 0.02 0.093 0.222 1.0 -0.166 89.0 90.0 NPHS2 -0.003 0.033 0.181 3.0 -9999.0 0.0 3.0 mol:IP3 0.02 0.093 0.222 1.0 -0.166 89.0 90.0 regulation of endocytosis 0.006 0.079 -9999.0 0.0 -0.15 92.0 92.0 Nephrin/NEPH1/podocin/Cholesterol 0.01 0.087 0.208 1.0 -0.163 91.0 92.0 establishment of cell polarity -0.009 0.105 0.188 1.0 -0.225 91.0 92.0 Nephrin/NEPH1/podocin/NCK1-2 0.03 0.092 0.231 1.0 -0.155 86.0 87.0 Nephrin/NEPH1/beta Arrestin2 0.008 0.081 -9999.0 0.0 -0.152 92.0 92.0 NPHS1 0.004 0.042 0.189 11.0 -9999.0 0.0 11.0 Nephrin/NEPH1/podocin 0.007 0.083 0.173 1.0 -0.159 92.0 93.0 TJP1 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.021 0.094 0.226 1.0 -0.167 89.0 90.0 CD2AP 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.022 0.094 0.226 1.0 -0.167 88.0 89.0 GRB2 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.05 0.095 0.223 12.0 -0.195 116.0 128.0 cytoskeleton organization -0.028 0.075 0.204 3.0 -0.195 77.0 80.0 Nephrin/NEPH1 0.0 0.074 0.129 10.0 -0.149 91.0 101.0 Nephrin/NEPH1/ZO-1 0.01 0.091 0.184 1.0 -0.177 89.0 90.0