Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.048 0.185 0.257 1.0 -0.38 90.0 91.0 MAP3K8 0.017 0.055 0.174 1.0 -0.31 13.0 14.0 FOS -0.039 0.146 0.24 2.0 -0.371 54.0 56.0 PRKCA 0.005 0.07 -9999.0 0.0 -0.31 22.0 22.0 PTPN7 0.024 0.039 0.173 22.0 -9999.0 0.0 22.0 HRAS 0.028 0.017 0.173 6.0 -9999.0 0.0 6.0 PRKCB -0.051 0.138 -9999.0 0.0 -0.311 107.0 107.0 NRAS 0.026 0.016 -9999.0 0.0 -0.317 1.0 1.0 RAS family/GTP 0.041 0.028 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.01 0.093 -9999.0 0.0 -0.359 9.0 9.0 MAP2K1 -0.081 0.207 -9999.0 0.0 -0.433 105.0 105.0 ELK1 0.017 0.023 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.065 0.18 -9999.0 0.0 -0.408 90.0 90.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.004 84.0 84.0 MAPK1 -0.015 0.109 -9999.0 0.0 -0.417 16.0 16.0 RAF1 -0.071 0.183 -9999.0 0.0 -0.396 101.0 101.0 KRAS 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0