Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.3 0.312 0.638 117.0 -9999.0 0.0 117.0 KIRREL -0.052 0.096 -9999.0 0.0 -0.38 17.0 17.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.301 0.313 -9999.0 0.0 -0.639 117.0 117.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.275 0.295 -9999.0 0.0 -0.545 128.0 128.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.211 0.23 -9999.0 0.0 -0.423 128.0 128.0 FYN -0.26 0.279 -9999.0 0.0 -0.516 128.0 128.0 mol:Ca2+ -0.271 0.291 -9999.0 0.0 -0.538 128.0 128.0 mol:DAG -0.273 0.293 -9999.0 0.0 -0.542 128.0 128.0 NPHS2 -0.129 0.267 -9999.0 0.0 -0.846 31.0 31.0 mol:IP3 -0.273 0.293 -9999.0 0.0 -0.542 128.0 128.0 regulation of endocytosis -0.242 0.262 -9999.0 0.0 -0.482 128.0 128.0 Nephrin/NEPH1/podocin/Cholesterol -0.279 0.298 -9999.0 0.0 -0.552 128.0 128.0 establishment of cell polarity -0.3 0.312 -9999.0 0.0 -0.638 117.0 117.0 Nephrin/NEPH1/podocin/NCK1-2 -0.252 0.274 -9999.0 0.0 -0.5 128.0 128.0 Nephrin/NEPH1/beta Arrestin2 -0.246 0.267 -9999.0 0.0 -0.489 128.0 128.0 NPHS1 -0.367 0.401 -9999.0 0.0 -0.812 116.0 116.0 Nephrin/NEPH1/podocin -0.262 0.282 -9999.0 0.0 -0.519 128.0 128.0 TJP1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.275 0.295 -9999.0 0.0 -0.545 128.0 128.0 CD2AP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.275 0.295 -9999.0 0.0 -0.545 128.0 128.0 GRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.259 0.275 -9999.0 0.0 -0.506 130.0 130.0 cytoskeleton organization -0.276 0.301 -9999.0 0.0 -0.552 128.0 128.0 Nephrin/NEPH1 -0.225 0.236 -9999.0 0.0 -0.48 117.0 117.0 Nephrin/NEPH1/ZO-1 -0.246 0.258 -9999.0 0.0 -0.525 117.0 117.0