Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.146 0.199 0.387 149.0 -9999.0 0.0 149.0 KIRREL -0.004 0.047 -9999.0 0.0 -0.54 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.146 0.199 -9999.0 0.0 -0.388 149.0 149.0 PLCG1 0.019 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.019 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.019 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.096 0.15 -9999.0 0.0 -0.277 150.0 150.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.084 0.141 -9999.0 0.0 -0.255 149.0 149.0 FYN -0.096 0.14 -9999.0 0.0 -0.266 149.0 149.0 mol:Ca2+ -0.095 0.148 -9999.0 0.0 -0.274 149.0 149.0 mol:DAG -0.095 0.149 -9999.0 0.0 -0.275 149.0 149.0 NPHS2 -0.019 0.026 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.095 0.149 -9999.0 0.0 -0.275 149.0 149.0 regulation of endocytosis -0.079 0.135 -9999.0 0.0 -0.243 149.0 149.0 Nephrin/NEPH1/podocin/Cholesterol -0.106 0.147 -9999.0 0.0 -0.284 149.0 149.0 establishment of cell polarity -0.146 0.199 -9999.0 0.0 -0.387 149.0 149.0 Nephrin/NEPH1/podocin/NCK1-2 -0.076 0.139 -9999.0 0.0 -0.244 149.0 149.0 Nephrin/NEPH1/beta Arrestin2 -0.08 0.137 -9999.0 0.0 -0.246 149.0 149.0 NPHS1 -0.211 0.268 -9999.0 0.0 -0.539 147.0 147.0 Nephrin/NEPH1/podocin -0.096 0.141 -9999.0 0.0 -0.267 149.0 149.0 TJP1 0.019 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.019 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.019 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.095 0.15 -9999.0 0.0 -0.276 149.0 149.0 CD2AP 0.017 0.029 -9999.0 0.0 -0.537 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 -0.095 0.15 -9999.0 0.0 -0.276 149.0 149.0 GRB2 0.019 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.099 0.138 -9999.0 0.0 -0.26 149.0 149.0 cytoskeleton organization -0.104 0.171 -9999.0 0.0 -0.311 149.0 149.0 Nephrin/NEPH1 -0.101 0.141 -9999.0 0.0 -0.272 149.0 149.0 Nephrin/NEPH1/ZO-1 -0.104 0.162 -9999.0 0.0 -0.3 149.0 149.0